Publications

* indicates mentored undergraduate or research associate co-author

^ indicates mentored graduate student or post-doctoral scholar co-author

# indicates last/corresponding author 

E. Kish*, T. Lee*, A. M. Ziemba^, A. Boamah*, B. Figuera*, M. Piccardi^, C.E. Dougan^, S.J. Moore, M.E. Buck#. “Combinatorial Synthesis of Protein-Polymer Conjugates by Post-Polymerization Modification of Poly(Pentafluorophenyl Acrylate)s.” ACS Omega, 2026. https://doi.org/10.1021/acsomega.5c07215 (Published as part of ACS Omega special issue “Undergraduate Research as the Stimulus for Scientific Progress in the USA”.)

R. Silvestri, M. Piccardi^, A.Laurenza, F. Rea, A.R. Sirois^, M. Lari, F. Bartoli, G. Signore, L. Tedeschi, E. Ferraro, P.A. Erba, R. Giovannoni, S. Landi, F. Gemignani#, S.J. Moore#. “Development of an engineered scaffold protein as a theranostic for pleural mesothelioma.” Bioconjugate Chemistry, 2025. https://doi.org/10.1021/acs.bioconjchem.5c00425

M. Piccardi^, V. Butera, I. Sardo, S. Landi, F. Gemignani, G. Barone, A. Spinello#, S.J. Moore#. “Computational modeling and experimental validation of the interaction between tumor biomarker mesothelin and an engineered targeting protein with therapeutic activity.” Protein Science, 2025. 34(9): e70263. https://doi.org/10.1002/pro.70263

A.R. Sirois^, D.A. Deny*, Y. Li*, Y. Fall*, S.J. Moore#. “Engineered Fn3 protein has targeted therapeutic effect on mesothelin-expressing cancer cells and increases tumor cell sensitivity to chemotherapy.” Biotechnology and Bioengineering, 2020. 117(2): 330-341. https://doi.org/10.1002/bit.27204. PMID: 31631324.

J. Kim*, A.R. Sirois^, A. Vazquez Cegla*, E. Jumai’an*, N. Murata*, M.E. Buck#, S.J. Moore#. “Protein-polymer conjugates synthesized using water-soluble azlactone-functionalized polymers enable receptor-specific cellular uptake toward targeted drug delivery.” Bioconjugate Chemistry, 2019. 30(4): 1220-1231. https://pubs.acs.org/doi/10.1021/acs.bioconjchem.9b00155.

A.R. Sirois^, D.A. Deny*, S.R. Baierl*, K.S. George*, S.J. Moore#. “Fn3 proteins engineered to recognize tumor biomarker mesothelin internalize upon binding.” PLOS ONE, 2018. 13(5): e0197029. https://doi.org/10.1371/journal.pone.0197029. 

S.J. Moore, M.G. Hayden Gephart, J.M. Bergen, Y.S. Su, H. Rayburn, M.P. Scott, J.R. Cochran. “Engineered knottin peptide enables non-invasive optical imaging of intracranial medulloblastoma.” Proc. Natl. Acad. Sci. USA, 2013.  110(36): 14598-14603.

S.J. Moore, C.L. Leung, H.K. Norton*, and J.R. Cochran.  “Engineering Agatoxin, a cystine-knot peptide from spider venom, as a molecular probe for in vivo tumor imaging.” PLOS ONE, 2013. 8: e60498.

H. Jiang, S.J. Moore, S. Liu, H. Liu, Z. Miao, F.V. Cochran, Y. Liu, M. Tian, J.R. Cochran, H. Zhang, and Z. Cheng. “A novel radiofluorinated agouti-related protein for tumor angiogenesis imaging.” Amino Acids, 2013. DOI: 10.1007/s00726-012-1391-y.

S.J. Moore and J.R. Cochran. “Engineering Knottins as Novel Binding Agents.” Methods in Enzymology, 2012. 503: 223-251.

S.J. Moore, C.L. Leung, and J.R. Cochran.  “Knottins: Disulfide-bonded Therapeutic and Diagnostic Peptides.” Drug Discovery Today: Technologies, 2012. 9: e3-e11.

S.J. Moore, M.J. Olsen, J.R. Cochran, and F.V. Cochran. (2009) “Cell Surface Display Systems for Protein Engineering” in Protein Engineering and Design, Sheldon J. Park and Jennifer R. Cochran, eds., Taylor and Francis, Boca Raton. Release date: September 25, 2009.