Foods

Abiraterone [1], foods ---> SmPC of [1] of EMA

ZYTIGA should be taken at least two hours after eating and no food should be eaten for at least one hour after taking the tablets. These should be swallowed whole with water.

Acamprosate, foods

The co-administration with foods decreases the bioavailibility

Acarbose [1], foods ---> SmPC of [1] of eMC

Acarbose tablets are administered orally and should be chewed with the first mouthful of food, or swallowed whole with a little liquid directly before the meal.

Acetazolamide, foods

Take with food; at least 6 hours before bedtime.

Activated dimeticone, foods

With or after each feed

Adenosine [1], foods ---> SmPC of [1] of eMC

Avoid caffeine, chocolate, cola and tea containing foods and drinks for at least 12 hours prior to use of adenosine

Afatinib [1], foods ---> SmPC of [1] of EMA

This medicinal product should be taken without food. Food should not be consumed for at least 3 hours before and at least 1 hour after taking this medicinal product

Alectinib [1], foods ---> SmPC of [1] of EMA

The hard capsules should be swallowed whole, and must not be opened or dissolved. They must be taken with food

Alendronate, foods

Patients must wait at least 30 minutes after taking alendronate before taking any other oral medicinal product

Alendronate, foods ---> SmPC of [alendronic acid/colecalciferol] of EMA

Alendronate must be taken with water only (not mineral water) at least 30 minutes before the first food, beverage, or medicinal product (including antacids, calcium supplements and vitamins) of the day.

Alendronate/colecalciferol [1], foods ---> SmPC of [1] of EMA

Patients must wait at least 30 minutes after taking alendronate before taking any other oral medicinal product

Alendronic acid, foods ---> SmPC of [alendronic acid/colecalciferol] of EMA

Alendronate must be taken with water only (not mineral water) at least 30 minutes before the first food, beverage, or medicinal product (including antacids, calcium supplements and vitamins) of the day.

Alendronic acid/colecalciferol [1], foods ---> SmPC of [1] of EMA

Alendronate must be taken with water only (not mineral water) at least 30 minutes before the first food, beverage, or medicinal product (including antacids, calcium supplements and vitamins) of the day.

Aliskiren [1], foods ---> SmPC of [1] of EMA

Concomitant administration of aliskiren with fruit juice or drinks containing plant extracts, including herbal teas, should be avoided.

Aliskiren/amlodipine [1], foods ---> SmPC of [1] of EMA

Meals (low or high fat content) have been shown to reduce the absorption of aliskiren substantially. Concomitant administration of aliskiren with fruit juice or drinks containing plant extracts, including herbal teas, should be avoided.

Aliskiren/amlodipine/hydrochlorothiazide [1], foods ---> SmPC of [1] of EMA

Meals (low or high fat content) have been shown to reduce the absorption of aliskiren substantially

Aliskiren/hydrochlorothiazide [1], foods ---> SmPC of [1] of EMA

Although meals (low or high fat content) have been shown to reduce the absorption of aliskiren substantially, the efficacy of aliskiren was shown to be similar when taken either with a light meal or without a meal

Allopurinol, foods

Take with a full glass of water.

Allopurinol/lesinurad [1], foods ---> SmPC of [1] of EMA

Duzallo should be taken in the morning with food and water.

Alogliptin/metformin [1], foods ---> SmPC of [1] of EMA

Vipdomet should be taken twice daily because of the pharmacokinetics of its metformin component. It should also be taken with meals to reduce the GI adverse reactions associated with metformin. The tablets should be swallowed whole with water.

Alpelisib [1], foods ---> SmPC of [1] of EMA

Piqray should be taken immediately after food, at approximately the same time each day (see section 5.2). The maximum recommended daily dose of Piqray is 300 mg.

Alprazolam, foods

Take with food

Ambrisentan [1], foods ---> SmPC of [1] of EMA

May be administered with or without food

Ambroxol, foods

Ambroxol syrup and drops should be taken with food.

Amifampridine [1], foods ---> SmPC of [1] of EMA

Tablets are to be taken with food.

Amiloride, foods

Take with food to reduce irritation.

Anagrelide [1], foods ---> SmPC of [1] of EMA

Food delays the absorption of anagrelide, but does not significantly alter systemic exposure.

Artemether/lumefantrine [1], foods ---> SmPC of [1] of eMC

Food enhances the absorption of both artemether and lumefantrine. Patients should be encouraged to take the medication with a normal diet as soon as food can be tolerated.

Asenapine [1], foods ---> SmPC of [1] of EMA

To ensure optimal absorption, eating and drinking should be avoided for 10 minutes after administration.

Atazanavir [1], foods ---> SmPC of [1] of EMA

To enhance bioavailability and minimise variability, REYATAZ is to be taken with food.

Atazanavir/cobicistat [1], foods ---> SmPC of [1] of EMA

To enhance bioavailability, EVOTAZ is to be taken with food.

Atazanavir/ritonavir, foods ---> SmPC of [atazanavir] of EMA

To enhance bioavailability and minimise variability, REYATAZ is to be taken with food.

Atovaquone [1], foods ---> SmPC of [1] of eMC

The importance of taking the full prescribed dose with food should be stressed to patients. The presence of food, particularly high fat food, increases bioavailability two to three fold.

Avatrombopag [1], foods ---> SmPC of [1] of EMA

Avatrombopag is recommended to be administered with food

Azithromycin, foods

Take on empty stomach, 1 hour before or 2 hours after meals.

Balsalazide, foods [2] ---> SmPC of [2] of eMC

Balsalazide should preferably be administered with food.

Bedaquiline [1], foods ---> SmPC of [1] of EMA

SIRTURO should be taken orally with food, as administration with food increases oral bioavailability by about 2-fold. SIRTURO tablets should be swallowed whole with water.

Betahistine, foods

Take this medication with food

Bexarotene [1], foods ---> SmPC of [1] of EMA

It is recommended that capsules be administered with food.

Bilastine [1], foods ---> SmPC of [1] of eMC

Food significantly reduces the oral bioavailability of bilastine by 30%.

Biphosphonates, foods

It is recommended that the tablets should be taken after an overnight fast (minimum 6 hours) and fasting should continue for at least 30 minutes after the dose has been taken

Boceprevir [1], foods ---> SmPC of [1] of EMA

Food enhanced the exposure of boceprevir. It should be administered with food

Bosutinib [1], foods ---> SmPC of [1] of EMA

Bosulif should be taken orally once daily with food (see section 5.2). If a dose is missed the patient should not be given an additional dose. The patient should take the usual prescribed dose on the following day.

Bromocriptine [1], foods ---> SmPC of [1] of eMC

Bromocriptine should always be taken with food.

Buprenorphine/naloxone [1], foods ---> SmPC of [1] of EMA

The tablet is to be placed under the tongue until completely dissolved. Patients should not swallow or consume food or drink until the tablet is completely dissolved.

Buspirone [1], foods ---> SmPC of [1] of eMC

Food increases the bioavailability of buspirone. Buspirone should be taken at the same time each day and consistently with or without food.

Cabotegravir [1], foods ---> SmPC of [1] of EMA

When administered with rilpivirine, cabotegravir tablets should be taken with a meal

Calcium carbonate [1], foods ---> SmPC of [1] of eMC

Certain foods (e.g. those containing oxalic acid, phosphate or phytinic acid) may reduce the absorption of calcium.

Canagliflozin [1], foods ---> SmPC of [1] of EMA

Invokana should be taken orally once a day, preferably before the first meal of the day. Tablets should be swallowed whole.

Cannabidiol [1], foods ---> SmPC of [1] of EMA

Food may increase cannabidiol levels and therefore it should be taken consistently either with or without food, including the ketogenic diet

Capecitabine [1], foods ---> SmPC of [1] of EMA

Since current safety and efficacy data are based upon administration with food, it is recommended that capecitabine be administered with food.

Cefpodoxime [1], foods ---> SmPC of [1] of eMC

The bioavailability increases if cefpodoxime is administered during meals.

Cefuroxime, foods

Optimum absorption occurs when cefuroxime is administered after a meal.

Celiprolol [1], foods ---> SmPC of [1] of eMC

It has been shown that the bioavailability of celiprolol is impaired when it is given with food.

Ceritinib [1], foods ---> SmPC of [1] of EMA

Ceritinib should be taken on an empty stomach. No food should be eaten for at least two hours before and two hours after the dose is taken.

Cholera vaccine (inactivated [1], oral), foods ---> SmPC of [1] of EMA

Food and drink should be avoided 1 hour before and 1 hour after vaccination

Cholic acid [1], foods ---> SmPC of [1] of EMA

Orphacol capsules must be taken with food at approximately the same time each day, in the morning and/or evening. Administration with food may increase cholic acid bioavailability and improve tolerability.

Cinacalcet [1], foods ---> SmPC of [1] of EMA

It is recommended that Mimpara be taken with food or shortly after a meal, as studies have shown that bioavailability of cinacalcet is increased when taken with food

Clodronate [1], foods ---> SmPC of [1] of eMC

Clodronate should in no case be taken with milk, food or drugs containing calcium or other divalent cations because they impair the absorption of clodronate.

Clodronic acid [1], foods ---> SmPC of [1] of eMC

Clodronate should in no case be taken with milk, food or drugs containing calcium or other divalent cations because they impair the absorption of clodronate.

Colesevelam [1], foods ---> SmPC of [1] of EMA

Cholestagel tablets should be taken orally with a meal and liquid.

Cyclosporine, foods

Fatty foods and the grapefruit juice increase absorption of ciclosporin

Cyproterone, foods

The tablets are to be taken with some liquid after meals.

Cysteamine [1], foods ---> SmPC of [1] of EMA

Cysteamine bitartrate should not be administered with food rich in fat or proteins, or with frozen food like ice-cream. Patients should try to consistently avoid meals and dairy products for at least 1 hour before and 1 hour after PROCYSBI dosing.

Dabrafenib [1], foods ---> SmPC of [1] of EMA

Patients should take dabrafenib at least 1 hour prior to or 2 hours after a meal due to the effect of food on dabrafenib absorption

Danazol, foods

The bioavailability increases when danazol is taken with a meal with a high fat content

Darolutamide [1], foods ---> SmPC of [1] of EMA

The tablets should be taken whole with food

Darunavir [1], foods ---> SmPC of [1] of EMA

Patients should be instructed to take PREZISTA with cobicistat or low dose ritonavir within 30 minutes after completion of a meal. The type of food does not affect the exposure to darunavir

Darunavir/cobicistat [1], foods ---> SmPC of [1] of EMA

When administered with food, the relative exposure of darunavir is 1.7-fold higher as compared to intake without food. Patients should be instructed to take REZOLSTA within 30 minutes after completion of a meal

Darunavir/cobicistat/emtricitabine/tenofovir alafenamide [1], foods ---> SmPC of [1] of EMA

Symtuza tablets should be taken with food. The type of food does not affect exposure to Symtuza.

Dasabuvir [1], foods ---> SmPC of [1] of EMA

To maximise absorption, Exviera tablets should be taken with food, without regard to fat and calorie content

Deferasirox [1], foods ---> SmPC of [1] of EMA

The bioavailability of deferasirox was increased to a variable extent when taken along with food. Deferasirox must therefore be taken on an empty stomach at least 30 minutes before food, preferably at the same time each day

Demeclocycline, foods [2] ---> SmPC of [2] of eMC

Absorption of demeclocycline is impaired by the concomitant administration of milk and dairy products, food, iron, calcium, zinc, magnesium and particularly aluminium salts commonly used as antacids.

Desmopressin, foods

A fat meal significantly decreased the absorption of desmopressin

Didanosine [1], foods ---> SmPC of [1] of eMC

To minimise the impact of food on the didanosine pharmacokinetics, didanosine should be administered on an empty stomach at least 2 hours before or 2 hours after a meal

Dimethyl fumarate [1], foods ---> SmPC of [1] of EMA

Food does not have a clinically significant effect on exposure of dimethyl fumarate. However, Tecfidera should be taken with food due to improved tolerability with respect to flushing or gastrointestinal adverse events

Dolutegravir [1], foods ---> SmPC of [1] of EMA

Dolutegravir is recommended to be taken with food by patients infected with HIV with integrase class resistance

Dolutegravir/rilpivirine [1], meal ---> SmPC of [1] of EMA

Juluca must be taken with a meal

Dronedarone [1], foods ---> SmPC of [1] of EMA

It is recommended to swallow the tablet whole with a drink of water during a meal. The tablet cannot be divided into equal doses.

Efavirenz [1], foods ---> SmPC of [1] of EMA

It is recommended that Efavirenz Teva be taken on an empty stomach, preferably at bedtime.

Elbasvir/grazoprevir [1], foods ---> SmPC of [1] of EMA

Elbasvir/grazoprevir may be taken without regard to food.

Eltrombopag [1], foods ---> SmPC of [1] of EMA

The tablets should be taken at least 2 hours before or 4 hours after any products such as antacids, dairy products (or other calcium containing food products), or mineral supplements containing polyvalent cations

Eluxadoline [1], foods ---> SmPC of [1] of EMA

The tablets should be taken with food in the morning and in the evening

Elvitegravir [1], foods ---> SmPC of [1] of EMA

Vitekta should be taken orally, once daily with food (see section 5.2). The film-coated tablet should not be chewed or crushed.

Elvitegravir/cobicistat/emtricitabine/tenofovir alafenamide [1], foods ---> SmPC of [1] of EMA

Genvoya should be taken orally, once daily with food. The film-coated tablet should not be chewed, crushed, or split.

Elvitegravir/cobicistat/emtricitabine/tenofovir disoproxil [1], foods ---> SmPC of [1] of EMA

Stribild should be taken orally, once daily with food. The film-coated tablet should not be chewed or crushed.

Empagliflozin/metformin [1], foods ---> SmPC of [1] of EMA

Synjardy should be taken twice daily with meals to reduce the gastrointestinal adverse reactions associated with metformin.

Emtricitabine/rilpivirine/tenofovir alafenamide [1], foods ---> SmPC of [1] of EMA

Odefsey should be taken orally, once daily with food. The film-coated tablet should not be chewed, crushed or split.

Emtricitabine/rilpivirine/tenofovir disoproxil [1], foods ---> SmPC of [1] of EMA

This medicinal product must be taken orally, once daily with food. It is recommended that the medicin be swallowed whole with water. The film-coated tablet should not be chewed or crushed as it may impact the absorption

Emtricitabine/tenofovir disoproxil [1], foods ---> SmPC of [1] of EMA

In order to optimise the absorption of tenofovir, it is recommended that Truvada should preferably be taken with food.

Entrectinib [1], foods ---> SmPC of [1] of EMA

Rozlytrek can be taken with or without food (see section 5.2) but should not be taken with grapefruit or grapefruit juice (see section 4.5).

Enzyme, foods

It is recommended to take the enzymes during or immediately after the meals.

Erlotinib [1], foods ---> SmPC of [1] of EMA

The recommended daily dose of Tarceva is 150 mg taken at least one hour before or two hours after the ingestion of food.

Estramustine, foods

Take on an empty stomach. Do not take with milk or milk products

Ethosuximide, foods

Take with food

Etidronate [1], foods ---> SmPC of [1] of eMC

Food in the stomach or upper portions of the small intestine, particularly materials with a high calcium content such as milk, may reduce absorption of etidronate disodium.

Etidronic acid [1], foods ---> SmPC of [1] of eMC

Food in the stomach or upper portions of the small intestine, particularly materials with a high calcium content such as milk, may reduce absorption of etidronate disodium.

Etravirine [1], foods ---> SmPC of [1] of EMA

The systemic exposure (AUC) to etravirine was decreased by about 50% when etravirine was administered under fasting conditions, as compared to administration following a meal. Therefore, etravirine should be taken following a meal.

Everolimus [1], foods ---> SmPC of [1] of EMA

High fat meals reduce systemic exposure to everolimus

Fampridine [1], foods ---> SmPC of [1] of EMA

It is recommended to take Fampyra without food

Fedratinib [1], foods ---> SmPC of [1] of EMA

Administration with a high fat meal may reduce the incidence of nausea and vomiting, therefore it is recommended to be taken with food.

Fenofibrate [1], foods ---> SmPC of [1] of eMC

Fenofibrate should always be taken with food, because it is less well absorbed from an empty stomach.

Ferric maltol [1], foods ---> SmPC of [1] of EMA

Feraccru capsules should be taken whole on an empty stomach (with half a glass of water), as the absorption of iron is reduced when Feraccru is taken with food

Flurbiprofen, foods

Take with food to reduce gastric irritation.

Foods, fostamatinib [2] ---> SmPC of [2] of EMA

The tablets should be taken twice daily, whole with or without food. In the event of gastric upset, tablets may be taken with food.

Foods, fostemsavir [2] ---> SmPC of [2] of EMA

Fostemsavir can be taken with or without food (see section 5.2). The prolonged-release tablet should be swallowed whole with water, and not chewed, crushed or split.

Foods, furosemide

Take with food to reduce irritation.

Foods, fusidic acid

Take with food to reduce irritation.

Foods, galantamine [2] ---> SmPC of [2] of eMC

It is recommended that galantamine be taken with food in order to minimize cholinergic undesirable effects.

Foods, gemfibrozil [2] ---> SmPC of [2] of eMC

As the presence of food alters the bioavailability slightly gemfibrozil should be taken 30 minutes before a meal.

Foods, glecaprevir/pibrentasvir [2] ---> SmPC of [2] of EMA

Take the tablets with food.

Foods, glimepiride [2] ---> SmPC of [2] of eMC

Glimepiride must be taken shortly before or during a meal.

Foods, guanfacin [2] ---> SmPC of [2] of EMA

Intuniv should not be administered with high fat meals due to increased exposure, as it has been shown that high fat meals have a significant effect on the absorption of guanfacine.

Foods, hydrocortisone

Take with food to reduce irritation.

Foods, hydroxycarbamide [2] ---> SmPC of [2] of EMA

The tablet should be taken once daily, preferably in the morning before breakfast and, where necessary, with a glass of water or a very small amount of food.

Foods, hydroxychloroquine

Each dose should be taken with a meal or glass of milk.

Foods, ibandronic acid [2] ---> SmPC of [2] of EMA

It is recommended that the tablets should be taken after an overnight fast (minimum 6 hours) and fasting should continue for at least 30 minutes after the dose has been taken

Foods, ibuprofen

The co-administration of ibuprofen with foods decreases the absorption rate

Foods, idebenone [2] ---> SmPC of [2] of EMA

Food increases the bioavailability of idebenone by approximately 5-7-fold and therefore, Raxone should always be administered with food. The tablets should not be broken or chewed.

Foods, imatinib [2] ---> SmPC of [2] of EMA

The prescribed dose should be administered orally with a meal and a large glass of water to minimise the risk of gastrointestinal irritations.

Foods, indinavir [2] ---> SmPC of [2] of EMA

For optimal absorption, CRIXIVAN should be administered without food but with water 1 hour before or 2 hours after a meal. Alternatively, CRIXIVAN may be administered with a low-fat, light meal.

Foods, isoniazid

Decreased absorption of isoniazid. Isoniazid must therefore be taken on an empty stomach

Foods, itraconazol [2] ---> SmPC of [2] of eMC

A maximum oral bioavailability is achieved if itraconazole is taken directly after a meal.

Foods, ivabradine [2] ---> SmPC of [2] of EMA

The intake during meals is recommended

Foods, ivacaftor [2] ---> SmPC of [2] of EMA

Kalydeco should be taken with fat-containing food. Food containing grapefruit or Seville oranges should be avoided during treatment with Kalydeco. Patients should be instructed to swallow the tablets whole

Foods, ivacaftor/tezacaftor/elexacaftor [2] ---> SmPC of [2] of EMA

Kaftrio tablets should be taken with fat-containing food.

Foods, ixazomib [2] ---> SmPC of [2] of EMA

NINLARO should be taken at approximately the same time on days 1, 8, and 15 of each treatment cycle at least 1 hour before or at least 2 hours after food

Foods, kebuzone

The intake during meals is recommended

Foods, lapatinib [2] ---> SmPC of [2] of EMA

The daily dose of lapatinib should not be divided. Lapatinib should be taken either at least one hour before, or at least one hour after food.

Foods, laropiprant/nicotinic acid [2] ---> SmPC of [2] of EMA

The tablets should be taken whole, with food, in the evening or at bedtime.

Foods, larotrectinib [2] ---> SmPC of [2] of EMA

The capsules can be taken with or without food but should not be taken with grapefruit or grapefruit juice.

Foods, lefamulin [2] ---> SmPC of [2] of EMA

Xenleta should be taken on an empty stomach, at least 1 hour before or 2 hours after a meal. This is because food and some drinks can affect the way medicines work.

Foods, lesinurad [2] ---> SmPC of [2] of EMA

Zurampic should be taken in the morning with food and water.

Foods, levodopa

High protein or iron meals may decrease the absorption of levodopa.

Foods, levodopa/benserazide [2] ---> SmPC of [2] of eMC

The peak levodopa plasma concentration is 30% lower and occurs later when levodopa/benserazide is administered after a standard meal. Food intake generally reduces the extent of levodopa absorption by 15% but this can be variable.

Foods, levodopa/carbidopa [2] ---> SmPC of [2] of EMA

Administration with a high-fat, high-calorie meal delays levodopa absorption by up to 2 hours

Foods, levodopa/carbidopa/entacapone [2] ---> SmPC of [2] of EMA

Meals rich in large neutral amino acids may delay and reduce the absorption of levodopa. Food does not significantly affect the absorption of entacapone.

Foods, levosulpiride

Should be taken at least 20 minutes before a meal

Foods, light paraffin

It should be administered 2 hours before or 2 hours after eating

Foods, linaclotide [2] ---> SmPC of [2] of EMA

The capsule should be taken at least 30 minutes before a meal

Foods, linagliptin/metformin [2] ---> SmPC of [2] of EMA

Jentadueto should be taken twice daily with meals to reduce the gastrointestinal adverse reactions associated with metformin

Foods, lisuride

Lisuride tablets should always be taken together with a snack or meal.

Foods, lixisenatide [2] ---> SmPC of [2] of EMA

Lixisenatide slows gastric emptying thereby reducing the rate at which meal-derived glucose appears in the circulation.

Foods, lomitapide [2] ---> SmPC of [2] of EMA

Administration with food may increase exposure to Lojuxta. Lojuxta should be taken on an empty stomach, at least 2 hours after the evening meal because the fat content of a recent meal may adversely impact gastrointestinal tolerability.

Foods, lopinavir

Take with food

Foods, lopinavir/ritonavir [2] ---> SmPC of [2] of EMA

Kaletra is administered orally and should always be taken with food

Foods, lornoxicam

Foods may decrease the absorption by ca. 20% and increase Tmax

Foods, lumacaftor/ivacaftor [2] ---> SmPC of [2] of EMA

Orkambi should be taken with fat-containing food. A fat-containing meal or snack should be consumed just before or just after dosing

Foods, lurasidone [2] ---> SmPC of [2] of EMA

Latuda film-coated tablets are for oral use, to be taken once daily together with a meal. If taken without food, it is anticipated that lurasidone exposure will be significantly lower as compared to when taken with food

Foods, manidipine

The absorption of manidipine increases in the presence of food in the gastrointestinal tract

Foods, mebeverine

Take mebeverine approximately 20 minutes before meals.

Foods, mecasermin [2] ---> SmPC of [2] of EMA

Mecasermin should be administered shortly before or after a meal or snack, because it may have insulin-like hypoglycaemic effects.

Foods, melatonin [2] ---> SmPC of [2] of EMA

The presence of food delayed the absorption of the melatonin resulting in a later and lower peak plasma concentration in the fed state

Foods, mercaptopurine [2] ---> SmPC of [2] of EMA

Xaluprine may be taken with food or on an empty stomach, but patients should standardise the method of administration. The dose should not be taken with milk or dairy products since they contain xanthine oxidase

Foods, mesalazine [2] ---> SmPC of [2] of eMC

Mesalazine is recommended to be administered with food

Foods, metformin [2] ---> SmPC of [2] of eMC

Food decreases the extent and slightly delays the absorption of metformin.

Foods, metformin/saxagliptin/dapagliflozin [2] ---> SmPC of [2] of EMA

Qtrilmet dose is taken orally once daily at the same time of the day with food to reduce the gastrointestinal adverse reactions associated with metformin. Each tablet is to be swallowed whole.

Foods, methylphenidate [2] ---> SmPC of [2] of eMC

Ingestion together with food with a high fat content delays its absorption (Tmax) by approximately one hour and increases the maximum concentration (Cmax) by approximately 30% and the amount absorbed (AUC) by approximately 17%

Foods, metronidazole

Take with food to reduce irritation.

Foods, midostaurin [2] ---> SmPC of [2] of EMA

Rydapt is recommended to be administered with food.

Foods, migalastat [2] ---> SmPC of [2] of EMA

Galafold exposure is decreased by approximately 40% when taken with food, therefore it should not be taken within 2 hours before and after food.

Foods, mitotane [2] ---> SmPC of [2] of EMA

The administration with fat-rich food enhances absorption of mitotane

Foods, naloxegol [2] ---> SmPC of [2] of EMA

Moventig should be taken on an empty stomach at least 30 minutes prior to the first meal of the day or 2 hours after the first meal of the day.

Foods, naltrexone/bupropion [2] ---> SmPC of [2] of EMA

Clinical experience included varying prandial conditions and supports the use of naltrexone / bupropion tablets with food.

Foods, nateglinide [2] ---> SmPC of [2] of EMA

It is recommended to administer prior to meals

Foods, nelfinavir [2] ---> SmPC of [2] of EMA

VIRACEPT is administered orally and should always be ingested with food

Foods, neratinib [2] ---> SmPC of [2] of EMA

Nerlynx should be taken with food, preferably in the morning.

Foods, nevirapine [2] ---> SmPC of [2] of EMA

The absorption of nevirapine is not affected by food, antacids or medicinal products which are formulated with an alkaline buffering agent.

Foods, nilotinib [2] ---> SmPC of [2] of EMA

The absorption and bioavailability of Tasigna are increased if it is taken with food, resulting in a higher serum concentration. Grapefruit juice and other foods that are known to inhibit CYP3A4 should be avoided.

Foods, nintedanib [2] ---> SmPC of [2] of EMA

Nintedanib capsules must be taken orally, preferably with food, swallowed whole with water, and must not be chewed or crushed.

Foods, nitisinone [2] ---> SmPC of [2] of EMA

Nitisinone has been co-administered with food during the generation of efficacy and safety data. Therefore, it is recommended that if nitisinone treatment with Orfadin hard capsules is initiated with food, this should be maintained on a routine basis

Foods, NSAID

Take with food to reduce the gastrointestinal irritation

Foods, olaparib [2] ---> SmPC of [2] of EMA

It is recommended that patients take Lynparza at least 1 hour after food, and refrain from eating preferably for up to 2 hours afterwards

Foods, ombitasvir/paritaprevir/ritonavir [2] ---> SmPC of [2] of EMA

To maximise absorption, Viekirax tablets should be taken with food, without regard to fat and calorie content

Foods, oral cholera vaccine

Food and drink should be avoided 1 hour before and 1 hour after vaccination

Foods, orlistat [2] ---> SmPC of [2] of EMA

Orlistat can be taken immediately before, during a meal or up to one hour after a meal. The capsule should be swallowed with water.

Foods, ospemifene [2] ---> SmPC of [2] of EMA

One tablet should be swallowed whole once daily with food and should be taken at the same time each day.

Foods, oxybutynine

Take with food.

Foods, palbociclib [2] ---> SmPC of [2] of EMA

IBRANCE is for oral use. It should be taken with food, preferably a meal to ensure consistent palbociclib exposure (see section 5.2). Palbociclib should not be taken with grapefruit or grapefruit juice

Foods, pancreas powder [2] ---> SmPC of [2] of EMA

Enzepi should be taken during meals or snacks, with a drink of water or juice. For paediatric patients below 1 year of age, Enzepi must be administered immediately prior to each feed.

Foods, patiromer [2] ---> SmPC of [2] of EMA

Veltassa should be taken with food. It should not be heated (e.g. microwaved) or added to heated foods or liquids. It should not be taken in its dry form.

Foods, pazopanib [2] ---> SmPC of [2] of EMA

Pazopanib should be taken without food, at least one hour before or two hours after a meal

Foods, peanut protein [2] ---> SmPC of [2] of EMA

Each dose taken at home should be consumed daily with a meal at approximately the same time each day, preferably in the evening. PALFORZIA should not be taken on an empty stomach or after fasting.

Foods, pentosan polysulfate

Administer on empty stomach at least 1 hour before or 2 hours after food.

Foods, pentosan polysulfate sodium [2] ---> SmPC of [2] of EMA

Take the capsules whole with one glass of water, at least 1 hour before or 2 hours after meals.

Foods, pentosan sulfate

Administer on empty stomach at least 1 hour before or 2 hours after food.

Foods, pidotimod

Decreased bioavailibility of pidotimod

Foods, pinaverium

Always take your tablets in the middle of a meal.

Foods, pioglitazone/metformin [2] ---> SmPC of [2] of EMA

Tablets should be swallowed with a glass of water. Taking Competact with, or just after food, may reduce gastrointestinal symptoms associated with metformin.

Foods, piperaquine/artenimol [2] ---> SmPC of [2] of EMA

Should be administered with water no less than 3 hours after the last food intake, and no food should be taken within 3 hours after each dose

Foods, pirfenidone [2] ---> SmPC of [2] of EMA

It is recommended to take with food to reduce the incidence of nausea and dizziness

Foods, piroxicam

Take with food

Foods, posaconazole [2] ---> SmPC of [2] of EMA

The absorption of posaconazole is significantly increased by food. Posaconazole should be taken with food or a nutritional supplement

Foods, potassium sodium hydrogen citrate

To be taken after eating

Foods, pretomanid [2] ---> SmPC of [2] of EMA

Pretomanid should be taken with food (see section 5.2). Tablets should be swallowed with water.

Foods, raltegravir [2] ---> SmPC of [2] of EMA

May be administered with or without food

Foods, reboxetine [2] ---> SmPC of [2] of eMC

Food intake delayed the absorption of reboxetine, but did not significantly influence the extent of absorption.

Foods, regorafenib [2] ---> SmPC of [2] of EMA

Stivarga should be taken at the same time each day. The tablets should be swallowed whole with water after a light meal that contains less than 30% fat.

Foods, repaglinide [2] ---> SmPC of [2] of EMA

Repaglinide should be taken before main meals (i.e. preprandially). Doses are usually taken within 15 minutes of the meal but time may vary from immediately preceding the meal to as long as 30 minutes before the meal

Foods, retinoids

The bioavailability of the retinoid increases in the presence of food. It is recommended that the retinoid be administered with a meal or shortly thereafter

Foods, ribavirin [2] ---> SmPC of [2] of EMA

The oral bioavailability was increased by coadministration of a high fat meal.

Foods, rifampicin

Rifampicin preferably be taken at least 30 minutes before a meal or 2 hours after a meal to ensure rapid and complete absorption.

Foods, rilpivirine [2] ---> SmPC of [2] of EMA

EDURANT must be taken with a meal to obtain optimal absorption

Foods, riluzole [2] ---> SmPC of [2] of EMA

The rate and extent of absorption is reduced when riluzole is administered with high-fat meals (decrease in Cmax of 44%, decrease in AUC of 17%).

Foods, risedronate [2] ---> SmPC of [2] of eMC

Foods interfere with the absorption of bisphosphonates and should not be taken at the same time

Foods, ritonavir [2] ---> SmPC of [2] of EMA

Ritonavir is recommended to be taken with food

Foods, rivastigmine [2] ---> SmPC of [2] of EMA

Administration of rivastigmine with food delays absorption (tmax) by 90 min and lowers Cmax and increases AUC by approximately 30%.

Foods, rufinamide [2] ---> SmPC of [2] of EMA

As a food effect was observed, Inovelon should be administered with food

Foods, sapropterin [2] ---> SmPC of [2] of EMA

The tablets should be administered with a meal as a single daily dose, to increase the absorption, and at the same time each day preferably in the morning.

Foods, saquinavir [2] ---> SmPC of [2] of EMA

Take this medication with food.

Foods, saxagliptin/metformin [2] ---> SmPC of [2] of EMA

Komboglyze should be given twice daily with meals to reduce the gastrointestinal adverse reactions associated with metformin.

Foods, selexipag [2] ---> SmPC of [2] of EMA

To improve tolerability, it is recommended to take Uptravi with food and, at the beginning of each up-titration phase, to take the first increased dose in the evening.

Foods, sevelamer carbonate [2] ---> SmPC of [2] of EMA

Renvela must be taken three times per day with meals.

Foods, simeprevir [2] ---> SmPC of [2] of EMA

Simeprevir must be taken with food. The type of food does not affect exposure to simeprevir.

Foods, simeticone

With or after each feed

Foods, sodium phenylbutyrate [2] ---> SmPC of [2] of EMA

PHEBURANE should be administered orally. Because of its slow dissolution, PHEBURANE should not be administered by nasogastric or gastrostomy tubes. The total daily dose should be divided into equal amounts and given with each meal or feeding

Foods, sofosbuvir [2] ---> SmPC of [2] of EMA

The film-coated tablet should not be chewed or crushed, due to the bitter taste of the active substance. The tablet should be taken with food

Foods, sofosbuvir/velpatasvir [2] ---> SmPC of [2] of EMA

Epclusa can be administered without regard to food.

Foods, sofosbuvir/velpatasvir/voxilaprevir [2] ---> SmPC of [2] of EMA

The recommended dose of Vosevi is one tablet, taken orally, once daily with food

Foods, sonidegib [2] ---> SmPC of [2] of EMA

The bioavailability of sonidegib is increased in the presence of food (see section 5.2). Odomzo must be taken at least two hours after a meal and at least one hour before the following meal.

Foods, sorafenib [2] ---> SmPC of [2] of EMA

Take the tablets at least 1 hour before or 2 hours after the meal.

Foods, stavudine [2] ---> SmPC of [2] of EMA

Should be taken on an empty stomach, and preferably at least 1 hour before a meal

Foods, stiripentol [2] ---> SmPC of [2] of EMA

The capsule should be swallowed whole with a glass of water during a meal. Stiripentol must always be taken with food as it degrades rapidly in an acidic environment (e.g. exposure to gastric acid in an empty stomach).

Foods, strontium ranelate [2] ---> SmPC of [2] of EMA

Food, milk and derivative products, and medicinal products containing calcium may reduce the bioavailability of strontium ranelate by approximately 60-70%. Therefore, administration of ranelate and such products should be separated by at least 2 hours

Foods, sucroferric oxyhydroxide [2] ---> SmPC of [2] of EMA

Velphoro is a chewable tablet that must be taken with meals.

Foods, sulindac

Decreased plasma levels of sulindac

Foods, tasimelteon [2] ---> SmPC of [2] of EMA

HETLIOZ should be taken without food; if patients eat a high-fat meal, it is recommended to wait at least 2 hours before taking HETLIOZ.

Foods, tegafur

Tegafur should be taken at least 1 hour before or 1 hour after a meal

Foods, tegafur/gimeracil/oteracil [2] ---> SmPC of [2] of EMA

The capsules should be taken by mouth with water at least 1 hour before or 1 hour after a meal

Foods, telaprevir [2] ---> SmPC of [2] of EMA

Telaprevir should be taken with food.

Foods, telotristat ethyl [2] ---> SmPC of [2] of EMA

Always take this medicine with a meal or some food.

Foods, temozolomide [2] ---> SmPC of [2] of EMA

Should be administered without food

Foods, tenofovir alafenamide [2] ---> SmPC of [2] of EMA

Vemlidy film-coated tablets should be taken with food.

Foods, tenofovir disoproxil [2] ---> SmPC of [2] of EMA

Tenofovir must be taken with food, as food enhances the bioavailability of tenofovir

Foods, testosterone undecanoate [2] ---> SmPC of [2] of eMC

Testosterone undecanoate be taken with a normal meal to ensure absorption.

Foods, tetracyclines

Decreased absorption of tetracycline. It is recommended to administer the two substances at least 3 hours apart.

Foods, tezacaftor/ivacaftor [2] ---> SmPC of [2] of EMA

Both Symkevi and ivacaftor tablets should be taken with fat-containing food, such as food recommended in standard nutritional guidelines

Foods, tipranavir [2] ---> SmPC of [2] of EMA

Should be given with food

Foods, tolperisone

The bioavailability increases when tolperisone is taken with a meal

Foods, trametinib [2] ---> SmPC of [2] of EMA

Patients should take trametinib as monotherapy or in combination with dabrafenib at least one hour prior to or two hours after a meal due to the effect of food on trametinib absorption

Foods, trientine [2] ---> SmPC of [2] of EMA

It is important that Cuprior is given on an empty stomach, at least one hour before meals or two hours after meals and at least one hour apart from any other medicinal product, food, or milk

Foods, trifluridine/tipiracil [2] ---> SmPC of [2] of EMA

In clinical studies Lonsurf was administered within 1 hour after completion of the morning and evening meals

Foods, troglitazone

Should be administered with food

Foods, venetoclax [2] ---> SmPC of [2] of EMA

The tablets should be taken with a meal in order to avoid a risk for lack of efficacy. The tablets should not be chewed, crushed, or broken before swallowing.

Foods, vildagliptin/metformin [2] ---> SmPC of [2] of EMA

Taking Icandra with or just after food may reduce gastrointestinal symptoms associated with metformin

Foods, voriconazole [2] ---> SmPC of [2] of EMA

VFEND film-coated tablets are to be taken at least one hour before, or one hour following, a meal.

Foods, zinc [2] ---> SmPC of [2] of EMA

Wilzin must be taken on an empty stomach, at least 1 hour before or 2-3 hours after meals.

Foods, zofenopril

Foods may reduce the rate but not the extent of absorption of zofenopril calcium.

Foods, zolpidem

Should not be administered with or immediately after a meal.

Irinotecan [1], meal ---> SmPC of [1] of EMA

Avoid eating grapefruits and drinking grapefruit juice while you are receiving ONIVYDE as it may increase the availability of the active substance of ONIVYDE in your body.