· In module Family Medicine and Public Health
· Luca is a 4-year-old boy, who has been brought to his GP with an episode of fever. His mother is keen for him to have antibiotics.
· MAIN CASE
Guidance and Resources – Feverish child in the community
Case Introduction – Feverish child in the community
Further Case Information – Feverish child in the community
Background Science – Feverish child in the community
Case Conclusion – Feverish child in the community
Formative Assessment – Feverish child in the community
CASE COMPONENT
Guidance and Resources – Feverish child in the community MED 35
In case FM&PH – Feverish child in the community
Reference materials and Resources
Here is a list of useful links for your information or reminders about what you have already covered in relation to this case. They are listed here for ease of reference and you may wish to return to this page after you’ve worked through the case, but review of any of this material before you start the case is not compulsory.
You will be directed to specific information contained within some of these links as you work through this case, but can come back to this list if you want further information or are interested to know more.
Recommended essential Readings/Resources
· HealthAwareness/EducationalContent/vaccination/Pages/vaccination1.
· NHS Choices: Why vaccinate your kids?
· Short video produced by Public Health England to address parental concern about vaccines and their child’s immune system.
· NICE Guideline: ‘Traffic Light Table’
· Acute Sore Throat (See Murtagh) see chapter 73
Additional Reading/Resources
· Chapter 1 The Green Book: Immunity and How Vaccination Works
· Vaccine Safety and Adverse Reactions
· GMC 0-18 years: Guidance for all doctors
· Prescribing Handbook 1 and Prescribing Handbook 2 (iBook links)
· NICE Guideline: Fever in the under 5s, assessment and initial management
· Personal Child Health Record also known as ‘The Red Book’
What you have already covered related to this case
· UHSM Adult Antimicrobial Guide (App) – Select ‘University Hospital South Manchester’ from the list of hospital trusts
· Infectious diseases (eBook)
· You have already come across some of the issues relating to vaccinations and it is a good idea to refresh your memory relating to the issues around vaccinations.
· You have also come across the previous case of measles.
CASE COMPONENT
Case Introduction – Feverish child in the community MED 35
In case FM&PH – Feverish child in the community
Luca has just turned 4 years old. His mother, Sofia, has brought him to an emergency GP appointment with Dr Walsh. Sofia tells her that he has ‘a cold again’. His symptoms started 3 days ago with a cough, and for the past 2 days he has been complaining of a cough. He has had a temperature which started last night. Luca ‘always seems to be chesty’ and Sofia wants some antibiotics for Luca so that he gets better quicker and can go back to nursery.
He has been well in himself, playing and eating and drinking, and passing urine as normal. He has not had any stridor, shortness of breath, drooling or difficulty swallowing. He is chatty in the consultation, and does not appear to have any features to suggest immediate admission is required (including audible stridor, difficulty breathing or altered consciousness).
From the medical record, Dr Walsh sees that Luca is not up to date with his routine childhood immunisations.
Have a look at KSA Childhood Immunisation Schedule. This is constantly updated so always best to check on-line for most up-to-date version.
What are the benefits of population vaccination programmes?
· Protects against infection or reduces the severity of infection
· Several infections are life-threatening (tetanus, diphtheria, Hib meningitis, Pneumococcal pneumonia, meningococcal disease), others have severe but rare complications (ie measles, polio).
· The greater number of children vaccinated, the more children in the community will be protected against an illness (including those who cannot have the vaccination for a particular disease e.g. certain medical conditions or their age). This is critical for measles and pertussis. This concept is often referred to as ‘herd’ immunity. Tetanus and diphtheria are for individual protection only.
Adapted from: http://www.nhs.uk/Conditions/vaccinations/Pages/reasons-to-have-your-child-vaccinated.aspx
Not all children are up-to-date with their vaccinations.
Reasons parents may not have arranged vaccination could include:
IN PRACTICE:
Spend time with a practice nurse when giving immunisations. What does he/she tell the parents? How does she/he give the vaccination? What questions does she/he ask before administration of the vaccine?
Sofia reports that for the past three months, Luca has been snotty and unwell about once a month. This has coincided with him starting nursery. She has always brought him to the GP for an emergency appointment, like this appointment today, but has been told that the infection is viral each time and Sofia feels that she has been ‘fobbed off’. She is very concerned today as Luca has a raised temperature for the first time. She has wanted antibiotics each time, but never asked the GP, until now.
What is a normal temperature?
· 33.5ºC - 34.5ºC
· 34.5ºC - 35.5ºC
· 35.5ºC - 36.5ºC
· 36.5ºC - 37.5ºC
· 37.5ºC - 38.5ºC
IN PRACTICE:
See how the GP assesses children. What is asked in the history? What examinations are done? What features does the GP consider increase the chance of an infection being bacterial vs. viral? How does the GP communicate to a parent about viral illnesses and the use of antibiotics?
CASE COMPONENT
Further Case Information – Feverish child in the community
In case FM&PH – Feverish child in the community
Before Dr Walsh discusses management with Sofia, she needs to make a careful assessment, as with any child, and particularly for a child with a history of fever. This involves ‘triadic consulting’ skills, which is where there is a history from a third party.
Accurate assessment of a child with fever is essential.
NICE have produced a guideline to help with the assessment of a child with fever, which helps the healthcare professional in the community assess risk, and if the child needs immediate treatment, or to be assessed in hospital and how urgently. This is often referred to as the ‘Traffic Light System’. The NICE guidelines are crucial reading here.
There are also specific symptoms and signs which indicate serious diseases and should always be considered.
Consider the following diseases, and drag and drop each of the symptoms to the corresponding disease which the sing or symptom can indicate
Dr Walsh takes a more thorough history, to enquire about any additional symptoms which Sofia has not yet mentioned, and specifically those which could indicate a serious condition as outlined in the table above.
She asks her about fevers specifically, and Sofia says that usually the temperature is around 37 degrees at home, but last night for the first time it was over 37.5, at 37.8. She feels that this definitely means that Luca needs antibiotics.
Dr Walsh also finds out through the consultation that Luca is Sofia’s only child and she is single parent, age 21, living in a one bedroom flat with Luca. She came to the UK five years ago from Lithuania, and has struggled to make ends meet. She is now working part time (3 days a week) and she can’t afford to take any more time off her work as a waitress in order to look after Luca when he is ill. This is partly why she wants antibiotics this time.
Sofia smokes 12 cigarettes per day, and has done so since she was 17.
Dr Walsh asks more about the cough, and if Sofia has noticed Luca seeming short of breath, which he has not. She also outlines what signs to look for in terms of increased work of breathing for future, and checks that Sofia has not seen any of these signs.
What signs should Sofia be looking out for which might indicate increased work of breathing?
Tracheal tug, recession, increased respiratory rate, abdominal breathing, cyanosis
You should try to see as many clinical signs in children as you can on your GP placements, and also during your Acute Illness block next year as assessment of children will form part of your Foundation Doctor work and training.
Dr Walsh has been looking at Luca during the consultation so far, and has noticed that he is alert and interested in his surroundings. He has not been drooling and there are no features in the history which alert Dr Walsh to epiglottitis.
What features might suggest epiglottitis?
Until recently, the typical presentation has been a 2–4 year old child with a short history of fever, irritability, dyspnoea, dysphonia and dysphagia, pooling of oral secretions, and drooling of saliva. The child may be sitting forward, breathing carefully. As the use of Haemophilus influenzae type b conjugated vaccine increases, the typical person presenting with epiglottitis is an adult rather than a child. Sore throat is the most prominent symptom in older children and adults [Burns and Hendley, 2005; Crook, 2010]. In this case, as Luca has not been vaccinated, it might increase the chance of this being the cause of his sore throat, but happily no features in the history here to support this differential.
Why is it important that Dr Walsh considers epiglottis before examining Luca’s throat?
There is a rapidly progressive cellulitis of the epiglottis and adjacent structures that has the potential to cause abrupt and complete airway obstruction. People with suspected epiglottitis should not have their throat examined unless there are facilities for immediate intubation/tracheotomy because of the possibility of precipitating complete airway obstruction or cardiopulmonary arrest [Burns and Hendley, 2005; Crook, 2010]
Taken from: https://cks.nice.org.uk/sore-throat-acute#!diagnosisadditional:6 References: Burns, J.E. and Hendley, J.O. (2005) Epiglottitis. In: Mandell, G.L., Bennett, J.E. and Dolin, R. (Eds.) Mandell, Douglas, and Bennett's principles and practice of infectious diseases. Volume 1, 6th edn. Philadelphia: Elsevier Churchill Livingstone. Chapter 56. Crook, D.W. (2010) Haemophilus influenzae. In: Warrell, D.A., Cox, T.M., Firth, J.D. and IN FILE (Eds.) Oxford textbook of medicine. 5th edn. Oxford: Oxford University Press. 759-762.
Dr Walsh examines Luca and notes the following:
· Red cheeks
· Snotty nose
· No photophobia
· No drooling
· Red enlarged tonsils but no exudates
· No neck stiffness
· No enlarged lymph glands
· Temperature is 37.7°C
· Respiratory rate is 24 breaths/minute, sat 99%, no increased work of breathing, chest is clear
· Heart rate is 100 beats/minute, heart sounds normal
· Warm, pink peripheries
· Capillary refill normal
· No rashes on full exposure
· Alert and smiling
· Abdomen soft, non-tender, normal bowel sounds
For children, it is important to consider a full examination and documentation of key findings, and including key negative findings.
What is the most likely diagnosis based on the history of sore throat, cough, coryzal symptoms and one episode of fever, and in combination with the examination findings above?
· Pneumonia
Pneumonia is not the most likely diagnosis. Although there is a history of cough, there is no increased work of breathing or Tachypnoea. The chest is clear with normal saturations. Heart rate is also normal. Another diagnosis is therefore more likely.
· Meningococcal septicaemia
.This is not the most likely diagnosis given the lack of symptoms which are consistent with this diagnosis (see table above), lack of supporting signs on examination (see table above) and normal physiological parameters (review the traffic light system above to check). However, it is always important to consider diagnoses that you wouldn’t want to miss.
· Tonsillitis/Pharyngitis
.
Correct answer.
This is a likely diagnosis given the history of sore throat, enlarged tonsils and fever. The physiological papameters put Luca in the low risk group, and so can at this stage be managed in the community and with his mum, without further specialist assessment.
Dr Walsh outlines to Sofia that she thinks that Luca has a throat infection. Sofia smiles and says ‘Great, I knew it. What antibiotic does Luca need?’
Does Luca require antibiotics?
Most sore throats are caused by viruses, and it is useful to outline this and the fact that antibiotics to do not help cure viruses any quicker than a person’s own immune system, and can be associated themselves with other unwanted effects, such as stomach upset.
There are different tools available which can be used to help decide if and when antibitoics are likely to be of benefit. CKS Guidelines suggest Centor Criteria, and Public Health England suggest FeverPAIN scoring systems. Please click on the links to discover more about these systems before you continue.
The GP might also consider antibiotics in certain other situations, including immunocompromise, systemic upset or valvular heart disease. A peritonsillar abscess or cellulitis on examination would require immediate admission.
What is the Centor Criteria?
The Centor criteria were developed to predict bacterial infection in people with acute sore throat (validated for children over 3 years). The four Centor criteria are:
· Presence of tonsillar exudate.
· Presence of tender anterior cervical lymphadenopathy or lymphadenitis.
· History of fever.
· Absence of cough.
The presence of three or four of these clinical signs (Centor score 3 or 4) suggests that the person may have bacterial infection (40–60% chance) and may benefit from antibiotics treatment.
The absence of three or four of these signs suggests that the person is unlikely to have an infection (80% chance), and antibiotics treatment is unlikely to be necessary.
An alternative is: FeverPAIN Score: Fever in last 24h
Purulence
Attend rapidly under 3d
severely Inflamed tonsils,
No cough or coryza.
Score:
0-1: 13-18% streptococci, use NO antibiotic strategy;
2-3: 34-40% streptococci, use 3 day back-up antibiotic;
4 or more: 62-65% streptococci, use immediate antibiotic if severe, or 48hr short back-up prescription
Always share self-care advice & safety net.
What is Luca’s Centor Criteria score?
· 1
· 2
· 3
· 4
1
The only one of the features that Luca has is fever.
Dr Walsh explains to Sofia that infections can be caused by different bugs, and antibiotics only work for infections caused by bacteria. Viruses are also commonly the cause of sore throat infections, and antibiotics do not do any good to fight viruses; Luca’s immune system will do the job. Dr Walsh outlines that she has listened carefully to what Sofia has told her, and examined Luca thoroughly. Dr Walsh explains that she thinks that Luca’s sore throat is caused by a virus, and that there are certain criteria which help us decide if antibiotics are going to be useful or not. She outlines that with a cough and without sore raised glands, and without white pus on the tonsils, the infection is more likely due to a virus than a bacteria. This means that antibiotics are unlikely to help get rid of the infection any quicker, and antibiotics themselves can cause other unwanted effects, such as tummy upset.
IN PRACTICE:
Watch how your GP communicates the risks of giving versus not giving antibiotics. How does the GP achieve shared partnerships with patients and their carers around investigation and management plans?
Sofia appreciates Dr Walsh taking the time to explain, and feels very reassured by what has been said. She outlines that she wouldn’t want to give Luca any medications if they are not going to definitely help.
Dr Walsh takes the opportunity to explore Sofia’s ideas, concerns and expectations around vaccination. Sofia says that she has been meaning to get Luca vaccinated, but has moved around the country and never ‘got round to it’. She was worried that because she’d missed her invitations, she had a ‘black mark against her name’ and wouldn’t now be allowed to get them. Dr Walsh reassured her that this was not the case, and invited her to make an appointment with the practice nurse to go through which vaccinations were required and provide any that were missing. Dr Walsh asked Sofia if she could bring along her ‘Red Book’ which Sofia said she would.
The Red Book
The Personal Child Health Record (PCHR), also known as ‘The Red Book’ is given out to all parents at the time of the baby’s birth, and is a record of health and development. It contains information about growth, including growth charts, and vaccinations. The parent keeps the record; it is not kept at the hospital or GP Surgery. An electronic version is currently being trialled.
IN PRACTICE:
If your practice does baby checks or vaccination clinics. See if you can watch what happens and have a look at a ‘Red Book’.
Dr Walsh also asks if Sofia would like to discuss her smoking, as she had mentioned it earlier in the consultation. Sofia says that she would not today as her priority is Luca. Dr Walsh leaves an open invitation to return in future if she would like to.
Dr Walsh advises that Sofia make sure that Luca rest and drink plenty, and advises paracetamol for fever and pain of the sore throat. In addition, ibuprofen could be tried. Sofia has both of these medications at home already, having bought them over the counter and had instructions on their use from the Pharmacist.
Read about prescribing for paediatric patients in Prescribing skills handbook 2. It is also a good idea to Familiarise yourself with the Children’s BNF
Dr Walsh makes sure that Sofia knows about the maximum doses. Dr Walsh also advises Sofia how to seek medical attention, either by contacting the GP surgery, if she is concerned about Luca and in particular if he develops any new symptoms, seems unwell in himself, seems unable to swallow, has noisy breathing or reduced oral intake. He advises her that Luca should be improved over the next 3 days, and if not Sofia should also contact the GP Surgery.
CASE COMPONENT
Background Science – Feverish child in the community MED 35
In case FM&PH – Feverish child in the community
Please ensure that you are familiar with the important information which we have covered in this case so far in relation to assessing children with fever, and the NICE guidelines are a very useful resource: NICE Guideline: ‘Traffic Light Table’. In addition, try to see your GP tutor assessing as many children as you can during your placement.
Primary Prevention is concerned with prevention of the onset of disease. As such, vaccination programmes are a good example, and occur at a population level.
You have already come across some of the issues relating to vaccinations and it is a good idea to refresh your memory relating to the issues around vaccination programmes.
You might also want to look at Green Book; ‘Immunisation against Infectious Disease’ Chapter 1 which outlines the principles of immunisations.
Chapter 2 outlines issues relating to consent.
CASE COMPONENT
Case Conclusion – Feverish child in the community MED 35
In case FM&PH – Feverish child in the community
Sofia books in with Dr Walsh eleven months later for a contraception review. Since seeing Dr Walsh, she has stopped smoking, moved into her own flat with a new partner and is feels as though her life has ‘turned around’. She thanks Dr Walsh for encouraging her to start thinking about stopping smoking. She says that Luca has been much better too since she was last in, and doesn’t seem to be having so many infections; in fact, he hasn’t had any for the past 6 months. He has caught up with his vaccinations. She has made friends with other mums now that Luca has started school, and feels that life is currently going well.
Formative Assessment – Feverish child in the community
What is the normal capillary refill time for a child of 2 years?
· <1 second
· <2 seconds
· <3 seconds
· <4 seconds
· <2 seconds
What serious underlying pathology would the following alert the GP to consider?
Non-blanching rash, particularly with 1 or more of the following:
• an ill-looking child
• lesions larger than 2 mm in diameter (purpura)
• capillary refill time of ≥3 seconds
• neck stiffness
· Bacterial meningitis
· Kawasaki disease
· Meningococcal septicaemia
· Pneumonia
Meningococcal septicaemia