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Essential Idea: Metabolic reactions are regulated in response to the cell’s needs
Essential Idea: Metabolic reactions are regulated in response to the cell’s needs
Understandings:
- Metabolic pathways consist of chains and cycles of enzyme-catalysed reactions.
- Enzymes lower the activation energy of the chemical reactions that they catalyse.
- Enzyme inhibitors can be competitive or non-competitive.
- Metabolic pathways can be controlled by end-product inhibition.
Applications:
- End-product inhibition of the pathway that converts threonine to isoleucine.
- Use of databases to identify potential new anti-malarial drugs.
Skills:
- Calculating and plotting rates of reaction from raw experimental results.
- Distinguishing different types of inhibition from graphs at specified substrate concentration.
Nature of science:
Developments in scientific research follow improvements in computing - developments in bioinformatics, such as the interrogation of databases, have facilitated research into metabolic pathways.
Introductory video:
Introductory video:
Powerpoint
Powerpoint
Useful Videos:
Useful Videos:
Skills and Application:
Skills and Application:
8.1 Metabolism Notes.pdfGoogle Sites
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