Brass Key
"I wonder what this opens..."
Embedded Files
Effect: When entering a new floor, has a chance to spawn a key in the starting room; there is a small chance this is replaced with a golden key
When holding Mom's Box, these chances are doubled
Cherry Bomb
"Just a bit of boom!"
"Just a bit of boom!"
Effect: When entering a new floor, has a chance to spawn a bomb in the starting room; there is a small chance this is replaced with a golden bomb
When holding Mom's Box, these chances are doubled
Crook
"From a shepherd figurine..."
"From a shepherd figurine..."
Effect: If Isaac has no Soul Hearts when entering a new floor, spawns a Soul Heart in the starting room
When holding Mom's Box, a Soul Heart will be spawned regardless of Isaac's health
Empty Syringe
"It's been used..."
"It's been used..."
Effect: When entering a new room, has a luck-based chance to apply Poison to enemies for a short time
When holding Mom's Box, this chance is doubled
Ghost Plushie
"Spooky!"
"Spooky!"
Effect: When entering a new room, has a luck-based chance to apply Fear to enemies for a short time
When holding Mom's Box, this chance is doubled
Goodie Bag
"Prize inside!"
"Prize inside!"
Effect: When entering a new floor, has a chance to spawn a random core pick-up in the starting room; there is a small chance Isaac instead receives one of each core pick-up
When holding Mom's Box, these chances are doubled
Heart of Gold
"It's leaking..."
"It's leaking..."
Effect: When entering a new room, has a luck-based chance to apply Midas Freeze to enemies for a short time
When holding Mom's Box, this chance is doubled
Letter Magnet
"It fell off the fridge.."
"It fell off the fridge.."
Effect: When entering a new room, has a luck-based chance to apply Magnetized to some enemies
When holding Mom's Box, this chance is doubled
Library Card
"I hope they're open!"
"I hope they're open!"
Effect: While held, automatically unlocks and opens Library doors
Love Letter
"Be my Valentine?"
"Be my Valentine?"
Effect: When entering a new room, has a luck-based chance to apply Charm to enemies for a short time
When holding Mom's Box, this chance is doubled
Makeshift Target
"Get 'em, boys!"
"Get 'em, boys!"
Effect: When entering a new room, has a luck-based chance to apply Baited to some enemies
When holding Mom's Box, this chance is doubled
Paring Knife
"Cut 'em up..."
"Cut 'em up..."
Effect: When entering a new room, has a luck-based chance to apply Bleed to some enemies
When holding Mom's Box, this chance is doubled
Participation Award
"I tried..."
"I tried..."
Effect: Increases Luck; each time Isaac takes damage on the floor, this bonus decreases, and is reset at the start of the next floor.
Has a chance to spawn after defeating a boss if Isaac is not awarded with Perfection or a health upgrade
Pet Snail
"Her name is Shelly..."
"Her name is Shelly..."
Effect: When entering a new room, has a luck-based chance to apply Slow to some enemies for a short time
When holding Mom's Box, this chance is doubled
Pet Snake
"His name is Gorgon..."
"His name is Gorgon..."
Effect: When entering a new room, has a luck-based chance to apply Freeze to enemies for a short time
When holding Mom's Box, this chance is doubled
Puzzle Piece
"It's confusing..."
"It's confusing..."
Effect: When entering a new room, has a luck-based chance to apply Shrink to enemies for a short time
When holding Mom's Box, this chance is doubled
Rabbit's Foot
"Lucky Charm"
"Lucky Charm"
Effect: Increases Luck
When holding Mom's Box, this bonus is doubled
Toy Blaster
"Shrink Ray"
"Shrink Ray"
Effect: When entering a new room, has a luck-based chance to apply Shrink to enemies for a short time
When holding Mom's Box, this chance is doubled
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