Effects: Decreases all six of Isaac's major stats by a small amount

Effects: Increases all six of Isaac's major stats by a small amount

Effects: Temporarily grants Flight; this effect is removed after entering five new rooms

Effects: Decreases Isaac's damage by a small amount

Effects: Increases Isaac's damage by a small amount

Effects: Gives Isaac two Black Hearts

Effects: Removes one Broken Heart

Effects: Adds one Broken Heart

Effects: Has a small chance to spawn a pile of poop as Isaac is shooting, up to three times total

Effects: Temporarily removes Flight; this effect is removed after entering five new rooms 

Effects: Grants a random passive item from the Angel pool, which is removed when entering a new room

Effects: Drops currently-held trinket, then gives one of the following at random:

• Fragmented Card

• Bloody Crown

• Silver Dollar

• Holy Crown

• Wicked Crown

Effects: Randomizes the currently-held Active Item and Trinket

Effects: Gives a random, one-time use die as a pocket active item

• This is removed if it is not used before entering a new room

Effects: Replaces all Red Heart containers with Bone Hearts