Schmidt & Brown (2021). Evidence-Based Practice for Nurses:
Chapter 4.3: Formulating EBP Questions
Describe the PICOT method
= A model in EBP used to formulate EBP questions; the mnemonic stands for patient population, intervention of interest, comparison of interest, outcome of interest, and time frame used to formulate EBP
P = Patient population or patient condition of interest
Needs to be carefully delineated so that the search for evidence yields relevant information and prevents retrieval of too broad or off-target information
Important to keep in mind that findings may not be generalizable to a specific patient
I = Intervention of interest
Requires similar delineation to yield focused, relevant information
When conducting a literature search, consider the main intervention or treatment, diagnostic test, procedure, or exposure
Consider any factors that may influence the prognosis, such as age, gender, ethnicity, coexisting conditions, and exposures to risk factors, such as cigarette smoke, asbestos, or other toxins
C = Comparison of interest
The intervention of interest can also be compared to the standard of care
A comparison with another intervention or treatment
Best to select the main alternative to the proposed intervention
O = Outcome of interest
The desired accomplishment, measurement, or improvement as a result of the selected intervention or treatment approach
Important to identify clear outcome measures to evaluate the efficacy of the intervention with the identified comparison
Specifying the desired outcome measures further refines the literature search
T = Time
This element is not always included
Timing, duration, or date of publication
Examples of PICOT Questions