A: Although I separate the Myo-Inositol powder from the Magnesium Citrate powder in the supplement guide, if you find that it is easier for you to combine them for bedtime consumption, I’ve not seen any issues with doing this.A: There is no difference in terms of what it does for you. Whether you're getting capsulated or powdered, you're going to want to make sure that there aren’t any potentially harmful additives. I find that it's nice to have powder forms of some supplements when you are taking so many capsules throughout the day. This is totally a personal preference. Some people like to have the magnesium drink at night, because it is flavored. So, it's just your own preference as to what you would like to take.