A: In the Specific Symptom Solutions Guide (in the Portal under the Handouts tab) there is information on how to use benfotiamine. The really interesting thing is that it can be a weight-based response. For example, my target dose was about 600 milligrams when I weighed about a hundred pounds. When my weight increased to about 120 pounds, that dose did not work as well for me anymore. I have a dosing table.
There was a study done by the Journal of Alternative and Complementary Medicine looking at thiamine and its individual target dose that found out it was actually weight-based. Depending on the person's body size, the dose ranges from 600 milligrams to 1500 milligrams per day.
Not sure if this is relevant for you, but essentially if your weight is above 60 kilograms, which is 132 pounds, then you might need a higher dose than 600 milligrams a day. The way they determined the target dose was by starting a person at 600 milligrams a day. Then every two days they would look at whether the person's fatigue and blood pressure issues had resolved. If they had not, they would increase the dose and check the person's heart rate to help determine the correct dose. If the dose was too high for the person, they would have an increased heart rate of more than a hundred beats per minute.
For the average person, if you're already at 600 milligrams a day, you weigh more than 120 or 130 pounds, and your fatigue and low blood pressure have not resolved yet, you may want to incrementally keep increasing the dose. If you have 50 milligram or 100 milligram capsules, increase it by that much, and check your fatigue and blood pressure every two days, while you keep monitoring your heart rate. If you're working with a practitioner, it may be helpful for them to help you monitor that as well.