OutlookShortcutKeys
Ctrl + Shift + I will take you straight to the Inbox.
Ctrl + Shift + O will put you into the Outbox.
Once you're in a mailbox:
Enter (while a message is highlighted) will open the message.
Ctrl + N will open a new e-mail message.
Ctrl + R will reply to the current message (either highlighted or already opened).
Ctrl + F will forward the current message (either highlighted or already opened).
Once you're in a message:
Tab will advance you one field forward (from the To: field to the Cc: field, etc).
Shift + Tab will send you one field backwards.
And finally (at least for this tip):
Ctrl + Enter will send your e-mail message.
OUTLOOK
Ctrl+Y Open folder window
Ctrl+D Delete message
Ctrl+S Save as draft
Ctrl+Q Mark as read or unread
Ctrl+K Check names typed in To, Cc and Bcc lists
F3 Launch Find
F7 Spell Check