Publications

1. Rajesh Singh Geeta Upadhyay, Amit Kapoor, Sanjeev Kumar, Ashok Kumar, Meenakshi Tiwari and Madan M. Godbole (2002) Hypothyroidism alters expression of Bcl-2 family genes to induce apoptosis in rat developing cerebellum. J Endocrinology 176(1): 39-46.

2. Rajesh Singh Geeta Upadhyay and Madan M. Godbole (2002) Hypothyroidism alters mitochondrial morphology to induce release of apoptogenic proteins in developing rat cerebellum. J Endocrinology 176(3):321-329.

3. Geeta Upadhyay, Rajesh Singh, Gaurav Agarwal, Lily Pal, Pradahn PK, Das BK, Saroj K. Misra and Madan M. Godbole (2002) Enhanced Expression of Sodium Iodide Symporter (hNIS) Gene in human breast carcinoma tissue. Breast Can Res Treatment 77:157-165.

4. Geeta Upadhyay, Rajesh Singh, Ramesh Sharma, Anil K Balapure, Madan M. Godbole (2002) Iodine acts directly on mitochondria from tumoral breast tissue to induce apoptosis independent of cytochrome c. Mitochondrion 2(3):199-210.

5. Geeta Upadhyay, Rajesh Singh, Amit Kapoor, Sanjeev Kumar, Ashok Kumar, Menakshi Tiwari and Madan M. Godbole (2004) Severe hyperthyroidism induces mitochondrial- mediated apoptosis in rat liver. Hepatalogy 39(4):1120-30.

6. Gupta S, Singh R*, Datta P, Zhang Z, Orr C, Lu Z, DuBois G, Zervos AS, Meisler MH, Srinivasula SM, Fernandes-Alnemri T, Alnemri ES (2004) The carboxy terminal tail of presenilin regulates Omi/HtrA2 protease activity. J Biol Chem. Oct 29;279(44):45844-54.

7. Kumar A, Sinha RA, Tiwari M, Pal L, Shrivastava A, Singh R, Kumar K, Kumar Gupta S, Godbole MM. (2006) Increased pro-Nerve Growth Factor and p75NTR levels in developing hypothyroid rat cerebral cortex are associated with enhanced apoptosis. Endocrinology 2006 Oct;147 (10):4893-903. Epub 2006 Jun 22

8. Kumar A, Sinha RA, Tiwari M, Singh R, Koji T, Manhas N, Rastogi L, Pal L, Shrivastava A, Sahu RP, Godbole MM. Hyperthyroidism induces apoptosis in rat liver through activation of death receptor-mediated pathways. J Hepatol. 2007 May;46(5):888-98. Epub 2007 Feb 5.

9. Tomar D, Singh R, Singh AK, Pandya CD, Singh R*. TRIM13 regulates ER stress induced autophagy and clonogenic ability of the cells. Biochim Biophys Acta. (Mol Cell Res) 2011 Dec 8;1823(2):316-326. [Epub ahead of print]

10. Singh AK, Singh R, Tomar D, Pandya CD, Singh R* (2012) The Leucine aminopeptidase of Staphylococcus aureus is secreted and contributes to biofilm formation. Int J Infect Dis. 2012 May;16(5):e375-81. Epub 2012 Mar 10.

11. Sripada L, Tomar D, Prajapati P, Singh R, Singh AK, Singh R* (2012) Systematic Analysis of Small RNAs Associated with Human Mitochondria by Deep Sequencing: Detailed Analysis of Mitochondrial Associated miRNA. PLoS ONE 7(9): e44873. doi:10.1371/journal.pone.0044873

12. Tomar D Prajapati P, Sripada L, Singh R, Singh AK, Singh R* (2012) Nucleo-cytoplasmic trafficking of TRIM8, a novel oncogene, is involved in positive regulation of TNF induced NF-κB pathway. PLoS One 2012;7(11):e48662. doi: 10.1371/journal.pone.0048662. Epub 2012 Nov 12

13. Sripada L, Tomar D, Singh R* (2012). Mitochondria: One of the destination of miRNA.

Mitochondrion Nov;12(6):593-9. doi: 10.1016/j.mito.2012.10.009. Epub 2012 Oct 17.

14. Tomar D Prajapati P, Sripada L, Singh R, Singh AK, Singh R* (2013) TRIM13 regulates caspase-8 ubiquitination, translocation to autophagosomes and activation during ER stress induced cell death. Biochim Biophys Acta. 2013 Sep 8;1833(12):3134-3144.

15. Rajpara N, Vinothkumar K, Mohanty P, Singh AK, Singh R, Sinha R, Nag D, Koley H, Kushwaha Bhardwaj A. Synergistic effect of various virulence factors leading to high toxicity of environmental V. cholerae non-O1/ non-O139 isolates lacking ctx gene : comparative study with clinical strains. PLoS One. 2013 Sep 23;8(9):e76200. doi: 10.1371/journal.pone.0076200.

16. Singh R, Sripada L, Singh R* (2013) "Side effects of antibiotics during bacterial infections: Mitochondria, the main target in host cell. Mitochondrion Nov 16. pii: S1567- 7249(13)00270-5. doi: 10.1016/j.mito.2013.10.005. [Epub ahead of print]

17. Bhatelia K, Singh A, Tomar D, Singh K, Sripada L, Chagtoo M, Prajapati P, Singh R, Godbole MM, Singh R*. Antiviral signaling protein MITA acts as a tumor suppressor in breast cancer by regulating NF-κB induced cell death. Mol Basis of Diseases (BBA). 2014 Feb;1842(2):144-53.

18. Tomar D, Singh R*. TRIM13 regulates ubiquitination and turnover of NEMO to suppress TNF induced NF-κB activation. Cell Signal. 2014 Dec;26(12):2606-13. [Epub ahead of print]

19. Bhatelia K, Singh K, Singh R*. TLRs: Linking inflammation and breast cancer. Cell Signal. 2014 Aug 3;26(11):2350-2357. doi: 10.1016/j.cellsig.2014.07.035. [Epub ahead of print] Review.

20. Tomar D, Singh R. TRIM family proteins; Emerging class of RING E3 ligases as regulator of NF-κB pathway. Biol Cell. 2014 Oct 16. doi: 10.1111/boc.201400046. [Epub ahead of print]

21. Prajapati P, Sripada L, Singh K, Bhatelia K, Singh R, Singh R*. TNF-α regulates miRNA targeting mitochondrial complex-I and induces cell death in Dopaminergic cells. BBA - Molecular Basis of Disease. Biochim Biophys Acta. 2015 Mar;1852(3):451-61. doi: 10.1016/j.bbadis.2014.11.019. Epub 2014 Dec 4.

22. Singh K, Poteryakhina A, Zheltukhin A, Bhatelia K, Prajapati P, Sripada L, Tomar D, Singh R, Singh AK, Chumakov PM, Singh R*. NLRX1 acts as tumor suppressor by regulating TNF-α induced apoptosis and metabolism in cancer cells. Mol Cell Res Biochim Biophys Acta. 2015 May;1853(5):1073-86. doi: 10.1016/j.bbamcr.2015.01.016. Epub 2015 Jan 30.

23. Tomar D, Prajapati P, Lavie J, Singh K, Lakshmi S, Bhatelia K, Roy M, Singh R, Bénard G, Singh R*. TRIM4; a novel mitochondrial interacting RING E3 ligase, sensitizes the cells to hydrogen peroxide (H2O2) induced cell death. Free Radic Biol Med. 2015 Oct 31;89:1036- 1048.. [Epub ahead of print]

24. Sripada L, Singh K, Lipatova AV, Singh A, Prajapati P, Tomar D, Bhatelia K, Roy M, Singh R, Godbole MM, Chumakov PM, Singh R*. hsa-miR-4485 regulates mitochondrial functions and inhibits the tumorigenicity of breast cancer cells. J Mol Med (Berl). 2017 Jun;95(6):641- 651.

25. Bhatelia K, Singh K, Prajapati P, Sripada L, Roy M, Singh R*. MITA modulated autophagy flux promotes cell death in breast cancer cells. Cell Signal. 2017 Mar 30. pii: S0898- 6568(17)30093-1. doi: 10.1016/j.cellsig.2017.03.024.

26. Singh AK, Patel P, Tomar D, Singh R, Sripada L, Prajapati P, Singh K, Singh R*. TBK1 regulates p62/sqstm1 mediated autophagic clearance of intracellular ubiquitinated Staphylococcus aureus in human epithelial cells. Transl Genet Genom 2017 May [Online First]

27. Prajapati P, Sripada L, Singh K, Roy M, Bhatelia K, Dalwadi P, Singh R*. Systemic Analysis of miRNAs in PD Stress Condition: miR-5701 Modulates Mitochondrial-Lysosomal Cross Talk to Regulate Neuronal Death. Mol Neurobiol. 2017 Jul 14. doi: 10.1007/s12035- 017-0664-6.

28. Roy M, Tomar D, Singh K, Lakshmi S, Prajapati P, Bhatelia K, Gohel D, Singh R*. TRIM8 regulated autophagy modulates the level of cleaved Caspase-3 subunit to inhibit genotoxic stress induced cell death. Cellular Signalling Volume 48, August 2018, Pages 1–12

29. Singh K, Sripada L, Lipatova A, Roy M, Prajapati P, Gohel D, Bhatelia K, Chumakov P M, Singh R*. NLRX1 resides in mitochondrial RNA granules and regulates mitochondrial RNA processing and bioenergetic adaptation, Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, Volume 1865, Issue 9, 2018. Pages 1260-1276

30. D. Gohel, L. Sripada, P. Prajapati, K. Singh, and M. Roy,.. Singh R* “FMRpolyG alters mitochondrial transcripts level and respiratory chain complex assembly in Fragile X associated tremor / ataxia syndrome [ FXTAS ],” BBA - Mol. Basis Dis., vol. 1865, no. 6, pp. 1379–1388, 2019.

31. Singh K, Roy M, Prajapati P, Lipatova L, Sripada L, Gohel D, Singh A, Mane M, Goddbole M, Chumakov PM, Singh R*, “NLRX1 regulates TNF-α-induced mitochondria-lysosomal crosstalk to maintain the invasive and metastatic potential of breast cancer cells.” BBA - Mol. Basis Dis., vol. 1865, no. 6, pp. 1460–1476, 2019.

32. P. Prajapati, P. Dalwadi, D. Gohel, K. Singh, L. Sripada, and K. Bhatelia, Singh R* “Enforced lysosomal biogenesis rescues erythromycin and clindamycin induced mitochondria mediated cell death in human cells,” Mol. Cell. Biochem., no. 0123456789, 2019.