NEW PROTOCOL FOR SCPD

SCPD (steady concentration peritoneal dialysis)

Presentations, forms, documentation and bibliography

Version Española aquí

Our method to increase ultrafiltration in peritoneal dialysis, that we call SCPD, steady concentration peritoneal dialysis, was first presented at the 2014 ISPD Congress and It was published in Peritoneal Dialysis International in 2016. We used a guideline inherited from our Peritoneal Nutrition studies in the 1980s, and we avoided with it the transfer to hemodialysis of patients unable to maintain their water balance with usual PD. In the years since 2014, experience has been accumulated on SCPD and mathematical models have been developed that allow us to better understand how it works and to adapt the original guideline to make it more effective and safe. We have developed a New Guideline optimizing SCPD, and we have prepared a presentation summarizing this history.

Here we supplement the information by adding the previous presentations of partial aspects in congresses, and providing access to a more complete bibliography, supporting documentation, nurses' guide, etc.

Previous presentations: 51 Congress of the Spanish Society of Nephrology SEN 2021 (Virtual)

P091.- [New guideline to increase UF and safety of steady concentration peritoneal dialysis SCPD]. V.Pérez Díaz et al. (Abstract) (Poster) (Explanatory audio)

P079.- [How steady concentration peritoneal dialysis SCPD is performed. Technical methodology and compliance with administrative requirements]. V. Oviedo Gómez et al. (Abstract) (Poster) (Explanatory audio)

Legal requirements:

Because concentrated glucose solutions and connections that are only available for intravenous use are used for SCPD, it is possible that the nephrologist must cover some specific legal requirement in each country to use them in PD. In Spain, the legal requirement to use drugs for use not included in their technical data sheet requires the physician to include in the patient's medical record 1) an explanation of the need to use them and 2) a consent form signed by the patient after informing him/her of the benefits and risks, attaching a copy of the technical data sheet.

Nurses’ Guidelines: Protocol of realization. Data collection sheet.

Bibliography

1. Pérez-Díaz V, Pérez-Escudero A, Sanz-Ballesteros S, Rodriguez Portela G, Valenciano-Martínez S, Palomo-Aparicio S, et al. A new method to increase ultrafiltration in peritoneal dialysis: Steady concentration peritoneal dialysis. Perit Dial Int [Internet]. 2016;36(5):555–61. Available from: https://doi.org/10.3747/pdi.2016.00007 (Paper)

2. De Alvaro F, Jimeno A, Pérez-Díaz V, Largo E, Ibañes E, Martin del Rio R, et al. Parenteral Nutrition via the Peritoneum with Dextrose and Amino Acids. Nephron [Internet]. 1987;46(1):49–56. Available from: https://www.karger.com/Article/FullText/184298 (Paper)

3. De Alvaro Moreno F, Pérez-Díaz V, Jimeno Carruez A, Largo Cabrerizo E, Martin del Rio R, Latorre A, et al. [Continuous peritoneal nutrition in CAPD patients]. Nefrologia [Internet]. 1988;8(Suppl 3):75–80. Available from: https://www.revistanefrologia.com/es-pdf-X0211699588041186?referer=buscador (Paper english & spanish)

4. Lee KJ, Shin DA, Lee HS, Lee JC. Computer simulations of steady concentration peritoneal dialysis. Perit Dial Int [Internet]. 2020;40(1):76–83. Available from: https://doi.org/10.1177/0896860819878635 (Paper)

5. Braide M. Steady Concentration PD (SCPD)—A New Concept with Interesting Opportunities. Perit Dial Int [Internet]. 2019 Nov 5;39(6):496–501. Available from: http://www.pdiconnect.com/lookup/doi/10.3747/pdi.2018.00265 (Paper)

6. Yuste C, Caro Espada PJ, Rodriguez Gayo L, Aguado B, Aranda MJ, Bada Bosch T, et al. Overhydration treatment with combined crystalloid and colloid PD solution. Nephrol Dial Transplant [Internet]. 2020 Jun 1;35(Supplement_3):iii9. Available from: https://academic.oup.com/ndt/article/doi/10.1093/ndt/gfaa139.SO007/5851990 (Paper)

7. Johansson A-C, Braide M, de Leon C, Persson E, Wramner L. Peritoneal ultrafiltration with a stable glucose concentration using the Carry Life® UF System. Nephrol Dial Transplant [Internet]. 2018 May 1;33(suppl_1):i526–i526. Available from: https://doi.org/10.1093/ndt/gfy104.SP529 (Paper) (Poster)

8. Carlsson O, Heimbürger O, Johansson A-C, Martus G, Wilkie M, Hegbrant J, et al. Increased removal rates of fluid an sodium during Steady Concentration Peritoneal Dialysis compared to Icodextrin and peritoneal equilibration test. Nephrol Dial Transplant [Internet]. 2020;35(suppl 3):iii1484. Available from: https://doi.org/10.1093/ndt/gfaa142.P1160 (Paper)

9. Heimbürger O, Martus G, Wilkie ME, Hegbrant JB, Carlsson O, De Leon C, et al. Steady concentration peritoneal dialysis increases ultrafiltration and sodium removal compared with continuous ambulatory peritoneal dialysis (CAPD). J Am Soc Nephrol [Internet]. 2020;31(kidney week abstract suppl):51. Available from: https://www.asn-online.org/education/kidneyweek/archives/KW20Abstracts.pdf (Paper)

10. Johansson A-C, Martus G, Wilkie M, Hegbrant J, Johansson A, De Leon C, et al. Increased sodium removal with steady concentration peritoneal dialysis. Am J Kidney Dis [Internet]. 2020;75(4):592. Available from: https://www.ajkd.org/article/S0272-6386(20)30239-0/fulltext (Paper)

11. Heimbürger O, Martus G, Wilkie M, Hegbrant J, Johansson A, De Leon C, et al. Increased peritoneal ultrafiltration at a lower metabolic cost during steady concentration peritoneal dialysis. Am J Kidney Dis [Internet]. 2020;75(4):585. Available from: https://www.ajkd.org/article/S0272-6386(20)30215-8/fulltext#relatedArticles (Paper)

12. Pérez-Díaz V, Pérez-Escudero A, Sanz-Ballesteros S, Sánchez-García L, Hernández-García E, Oviedo-Gómez V, et al. Clinical relevance of marginal factors on ultrafiltration in peritoneal dialysis. Perit Dial Int [Internet]. 2021 Jan 12;41(1):86–95. Available from: http://journals.sagepub.com/doi/10.1177/0896860820904556 (Paper)

13. Pérez-Díaz V, Fernández-Reyes MJ, Pérez-Escudero A, Sánchez-García L, Rodríguez-Gómez A, Felipe-Fernández C, et al. Effect of intraperitoneal pressure on ultrafiltration of peritoneal equilibration test 4hour/3.86% glucose. Nephrol Dial Transplant [Internet]. 2018 May 1;33(suppl_1):i517–i517. Available from: https://doi.org/10.1093/ndt/gfy104.SP500 (Paper) (Poster)

14. Sobrino-Pérez A, Pérez-Escudero A, Fernández-Arroyo L, Dorado-García A, Martín-Alcón B, Gutiérrez-Martín C, et al. Intraperitoneal pressure: Stability over time and validation of Durand’s measurement method. Perit Dial Int J Int Soc Perit Dial [Internet]. 2020 Nov 28;41(4):427–31. Available from: http://journals.sagepub.com/doi/10.1177/0896860820973120 (Paper)

15. Pérez-Díaz V, De Álvaro-Moreno F, Jimeno-Carruez A. Nutrición Peritoneal Total / Total Peritoneal Nutrition. In: Rodicio JL, editor. 25 Aniversario Servicio Nefrología Hospital “12 de Octubre”, Madrid (Spain) 1999. Madrid; 1999. (Presentarion English)

16 Rodriguez Portela G, Valenciano-Martínez S, Palomo-Aparicio S, Vasquez-Blandino DE, Sanz-Ballesteros S, Gordillo-Martin R, et al. Treatment of fluid overload in PD by the method of Continuous Peritoneal Nutrition. In: 15th Congress of the International Society for Peritoneal Dialysis. Madrid; 2014. p. 243.P. (Poster)

17 Braide M, Johansson A. Ultrafiltration and solute transport in steady concentration PD: Theoretical modelling and experimental data from PD patients. ISPD EuroPD 2021. Book of Abstracts P 95. (Paper) (Poster)

18 Wang T, Heimburger O, Cheng HH, Waniewski J, Bergstrom J, Lindholm B. Effect of increased dialysate fill volume on peritoneal fluid and solute transport. Kidney Int. 1997;52(4):1068–76. (Paper)

19 Sobrino-Pérez A, Pérez-Díaz V, Sánchez-García L, Sanz-Ballesteros S, Hernández-García E, Oviedo-Gómez V, et al. [Increasing the concentration of peritoneal solutions decreases the effect of intraperitoneal pressure on ultrafiltration]. In: XI Reunión Nacional de Diálisis Peritoneal y Hemodiálisis Domiciliaria. Zamora, Spain.; 2020. p. 69. (Paper) (Poster English & Español)

20. Heimbürger O, Martus G, Wilkie M, Hegbrant J, Johansson A, Carlsson O, et al. Increased ultrafiltration at lower metabolic cost durng steady concentration PD. ISPD EuroPD 2021. Book of Abstracts P 118. (Paper) (Poster)

21. Johansson A-C, Martus G, Wilkie M, Hegbrant J, Johansson A, De Leon C, et al. Increased sodium removal with steady concentration peritoneal dialysis. ISPD EuroPD 2021. Book of Abstracts P 117. (Paper) (Poster)

22. Martus G, Johansson A-C, Wilkie M, Hegbrant J, Johansson A, De Leon C, et al. Steady concentration peritoneal dialysis as an alternative to icodextrin. Am J Kidney Dis. 2020;75(4):605 (Paper)

23. Johansson A-C, Braide M, de Leon C, Persson E, Greatrex P, Wramner L. P-94 Peritoneal ultrafiltration with a stable glucose concentration using the Carry Life (r) System. In: ISPD EuroPD Meeting 2019 [Internet]. 2019. p. 103. Available from: http://www.europd.com/wp-content/uploads/2019/04/EuroPD-2019-Abstract-Book.pdf (Paper)

24. Yuste C, Caro Espada PJ, Rodriguez Gallo L, Aguado B, Aranda MJ, Bada Bosch T, et al. Tratamiento de la sobrehidratación mediante el uso de soluciones mixtas. In: XI Reunión Nacional de Diálisis Peritoneal y Hemodiálisis Domiciliaria. Zamora, Spain.; 2020. p. 85–6. (Paper)

25. Carlsson O, Johansson A-C, Heimbürger O, Martus G, Wilkie M, Hegbrant J, et al. Steady Concentration Peritoneal Dialysis increases ultrafiltration and sodium removal compared to CAPD. Nephrol Dial Transplant [Internet]. 2020 Jun 1;35(Supplement_3). Available from: https://academic.oup.com/ndt/article/doi/10.1093/ndt/gfaa144.P1131/5853821 (Paper)

26. Yuste C, Caro Espada PJ, Rodriguez Gayo L, Aguado B, Aranda MJ, Bada Bosch T, et al. Overhydration treatment with combined chrystalloid and colloid PD solution. ISPD EuroPD 2021. Book of Abstracts P 218. (Paper) (Poster)