This page reviews a line of investigation initiated with peritoneal nutrition and followed by its effect on ultrafiltration and the effect that intraperitoneal pressure has on it. From here we can go to each of the chapters. In addition, we have prepared some presentations showing an overview of all the research, one updated to 2018 and the other to 2021.
1.- CONTINUOUS PERITONEAL NUTRITION.- Since 1983 we have been developing an effective and safe method of complete parenteral nutrition through the peritoneal membrane as safe and efficient as universally used intravenous parenteral nutrition, which could also be combined with peritoneal dialysis. In 2013 we tried to re-disseminate those investigations among nephrologists. On this page we present the technique, the bibliography generated and our presentations of 2013-14 recalling the technique.
2.- SCPD. INCREASING ULTRAFILTRATION IN PD: Continuous Peritoneal Nutrition always caused an increase in ultrafiltration that had to be monitored. Since 2014 we took advantage of this feature to avoid transfer to HD of patients with refractory fluid overload. We call our method SCPD, Steady Concentration Peritoneal Dialysis. This method may become a useful tool to treat events of fluid overload in peritoneal dialysis patients and for the long-term management of peritoneal dialysis patients with compromised UF.
Since 2014, several clinical applications and mathematical models of SCPD have been published which, together with our own experiences and our studies on the factors that modulate UF in SCPD, have allowed us to propose in 2021 a new, more effective and safer protocol for performing SCPD.
3.- INTRAPERITONEAL PRESSURE (IPP) IN PERITONEAL DIALYSIS AND ITS EFFECT ON ULTRAFILTRATION. The effect of SCPD varies greatly even in the same patient. One of the factors responsible was the intraperitoneal pressure produced by the UF itself. Other factors were the degree of overhydration and hypoalbuminemia. And there was a strange influence of sex.
(Go to TFG and subject review)
(Go to IPP Experiment with 1.5 and 2.5L 2.27% glucose)
(Go to PET Experiment 3.86% with 1 and 2L)
4.- THE PIPDPCyL WORKING GROUP. Along the way we built a network of collaborators, the PIPDPCyL Group, acronym in Spanish for intraperitoneal pressure, peritoneal dialysis and Castilla y León, where all the associated centers are located.