adversereactiontotransfusiongeneral:
Adverse Reaction to Transfusion general
ADVERSE REACTIONS TO BLOOD TRANSFUSION:
ADVERSE REACTIONS TO BLOOD TRANSFUSION:
Any adverse reaction that occurs during the administration of blood and blood component must be considered as transfusion reaction unless proved otherwise.
Transfusion reactions occur in 7% to 10% of all recipient of blood or blood components.
Fortunately, majority of them are minor reactions.
10% of these reactions are hemolytic and 90% of these are nonhemolytic reactions.
Incidence of ABO mismatch blood being infused is 1 : 30,000 blood bag.
1 out of 10 ABO mismatch transfusion is fatal .
Transfusion reactions may be divided as follows :
Transfusion reactions may be divided as follows :
ACUTE (<24 hrs):
ACUTE (<24 hrs):
clinical pearls:
clinical pearls:
any reaction which occurs during transfusion is a transfusion reaction unless proved other wise.
Delayed adverse reactions to Transfusion (<24 hrs) :
Delayed adverse reactions to Transfusion (<24 hrs) :
Nonimmunologic :
Nonimmunologic :
Iron overload
Transfusion transmitted diseases
multiple transfusion.
Hepatitis, HIV cytomegalovirus etc.