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The central objective of this project is to create a highly sensitive, high-throughput sensor using an innovative label free magnetic cell detection method based on magnetic microparticle-cell attachment for simultaneous, parallel detection of multiple pathogen cells. The sensor is expected to provide information of existence and concentration of multiple pathogen cells in a sample. To achieve the goals, in Year 3 our activities were divided into two major parts: (1) to research an innovative label free magnetic cell detection method based on magnetic microparticle-cell attachment for cell identification and development of a novel cell sensing surface, and (2) to study resistive pulse sensing method for pathogen cell detection. The details of the activities are described below.
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