Since the first report of Dengue case in 1968, dengue has become a public health problem in Thailand almost fifty years. Every year at least 30,000 dengue cases, i.e. dengue fever, dengue hemorrhagic fever and dengue shock syndrome, were reported and four dengue serotypes were found among them. In 2018, the dengue situation is much worse than previous two years; number of report dengue cases in the first trimester was higher than the previous. Although Thai Ministry of Public Health has implement several dengue prevention and control measures, the country cannot win the disease. However in some areas of the central part of Thailand have reported dengue free zone for 20 years continually. Those areas implemented dual surveillance systems, Integrate Vector Management (IVM), Community Participation approach, and Surveillance Rapid Response Team. The lesson learns will be demonstrated through concepts, system, and actual practice and differentiated factors with those failure areas.