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By AurametrixAccording to the recent Results From Annual Screens (April 2009), screening tests for ovarian cancer fail to detect the early signs of the disease, yet positive screens often result in unnecessary surgery.
Better tests are needed and you can help to develop the technology.
If you are a woman with endometriosis,polycystic ovarian syndrome, recurrent biopsy-confirmed ovarian cancer, fallopian tube cancer, or primary peritoneal cancer, we invite you to be a research volunteer, to help in the discovery of a simple non-invasive test for diagnostics of ovarian cancer and related conditions. The study will last two years, and will involve up to 4 visits to San Anselmo, California.
All you do is breathe in a tube for a few minutes. Chemicals in the breath will be used to develop a test for early diagnostics of ovarian cancer. Ashley McKnight, the study coordinator, can be reached at (415) 342-0886.
Read more about the study here:
http://www.pinestreetfoundation.org/recruitment/patient.html
http://clinicaltrials.gov/ct2/show/NCT00757952
Location: 124 Pine St, San Anselmo, CA
O (Oprah) Magazine featured a story about this study in June 2009 issue.
Other Currently Recruiting Diagnostic Clinical Trials
http://clinicaltrials.gov/ct2/show/NCT00267072
Ovarian Screening Study (James Graham Brown Cancer Center)
Objectives:To identify women at increased risk for developing ovarian cancer; To detect ovarian cancers at an early stage; To investigate the role of tumor membrane fragments as tumor markers for early ovarian carcinoma
http://clinicaltrials.gov/ct2/show/NCT00039559
Clinical Trial to Screen Participants Who Are at High Genetic Risk for Ovarian Cancer (Massachusetts General Hospital)
Interventions: screening questionnaire administration ; study of high risk factors
http://clinicaltrials.gov/ct2/show/NCT00045214
Study of Individuals and Families at High Risk for Breast or Ovarian Cancer (National Cancer Institute, NCI)
Interventions: gene mapping, mutation analysis, questionnaire administration; biopsy, breast duct lavage, breast imaging study, magnetic resonance imaging, mammography, study of high risk factors
http://clinicaltrials.gov/ct2/show/NCT00539162
CA 125 Algorithm for the Early Detection of Ovarian Cancer (MD Anderson Cancer Center)
Intervention: Questionnaire
Currently Available Preventive Screening Tests
For women with a BRCA mutation, American College if Obstetricians and Gynecologists recommends periodic screening with CA-125 test and transvaginal ultrasonography beginning between the ages of 30 and 35 years or 5-10 years earlier than the earliest age of first diagnosis of ovarian cancer in the family.
Risk-reducing salpingo-oophorectomy surgery—which removes both of the ovaries and fallopian tubes—can reduce the risk of ovarian and fallopian tube cancer by about 85% to 90% among BRCA carriers. Women who have BRCA1or BRCA2mutations or HNPCC mutation should be offered risk-reducing salpingo-oophorectomy by age 40/45 or when childbearing is complete. The ideal time for this surgery depends on the type of gene mutation.
Routine Screening for Hereditary Breast and Ovarian Cancer Recommended
Many Factors to Consider Before Removing Ovaries to Reduce Cancer Risk
Removing Ovaries before menopause can lead to memory and movement problems – Science News
Statistics:
85-90% of ovarian cancers occur in women without a family history. There is a 1.5% probability that a woman develops ovarian cancer by the age of 70; it’s 5% if it runs in your family ; 18 to 50% if it is in your genes. The risk is higher for obese women (BMI >30), those that have used fertility drugs, hormones, and some endometriosis medications, and it goes up with age.
Ovarian cancer hotline
Women or family members interested in volunteering for the hotline can contact Theresa Conti at ovarianconsultant@sharecancersupport.org or leave a message on the hotline stating their interest. Women who wish to speak with an ovarian cancer survivor can call the toll-free Ovarian Cancer Hotline at (866)-53SHARE.
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