Ionizable compounds

M.J. Ruiz-Ángel, S. Carda-Broch, A. Levet, A. Berthod, “Hydrophobicity of ionisable compounds studied by countercurrent chromatography”. Journal of Chromatography A 1218, 6044–6052 (2011).

J.R. Torres-Lapasió, S. Pous-Torres, J.J. Baeza-Baeza, M.C. García-Álvarez-Coque, “Optimal experimental designs in RPLC at variable solvent content and pH based on prediction error surfaces”. Analytical and Bioanalytical Chemistry 400, 1217–1230 (2011).

M.J. Ruiz-Ángel, J.R. Torres-Lapasió, M.C. García-Álvarez-Coque, “The midpoint method: a shortcut approach to calculate the pH”. The Chemical Educator 15, 90–99 (2010).

S. Pous-Torres, J.R. Torres-Lapasió, J.J. Baeza-Baeza, M.C. García-Álvarez-Coque, “Combined effect of solvent content, temperature and pH on the chromatographic behaviour of ionisable compounds. III: Considerations about robustness”. Journal of Chromatography A 1216, 8891–8903 (2009).

S. Pous-Torres, J.R. Torres-Lapasió, J.J. Baeza-Baeza, M.C. García-Álvarez-Coque, “Combined effect of solvent content, temperature and pH on the chromatographic behaviour of ionisable compounds. II: Benefits of the simultaneous optimisation”. Journal of Chromatography A 1193, 117–128 (2008).

J.R. Torres-Lapasió, M.C. García-Álvarez-Coque, E. Bosch, M. Rosés, “Considerations on the modelling and optimisation of resolution of ionisable compounds in extended pH-range columns”. Journal of Chromatography A 1089, 170–186 (2005).

S. Pous-Torres, J.R. Torres-Lapasió, J.J. Baeza-Baeza, M.C. García-Álvarez-Coque, “Combined effect of solvent content, temperature and pH on the chromatographic behaviour of ionisable compounds”. Journal of Chromatography A 1163, 49–62 (2007).

M.J. Ruiz-Ángel, S. Carda-Broch, M.C. García-Álvarez-Coque, A. Berthod, “Micellar versus hydro‑organic mobile phases for retention-hydrophobicity relationship studies with ionizable diuretics and an anionic surfactant”. Journal of Chromatography A 1030, 279–288 (2004).

M.J. Ruiz-Ángel, J.R. Torres-Lapasió, M.C. García-Álvarez-Coque, “Effect of pH and the presence of micelles on the resolution of diuretics by reversed-phase liquid chromatography”. Journal of Chromatography A 1022, 51–65 (2004).

J.J. Baeza-Baeza, M.C. García-Álvarez-Coque, “Some observations on the prediction of retention in reversed-phase liquid chromatography using the pH as main factor”. Analytica Chimica Acta 521, 61–68 (2004).

J.R. Torres-Lapasió, D.L. Massart, J.J. Baeza-Baeza, M.C. García-Álvarez-Coque, “A three-factor optimisation strategy for micellar liquid chromatography”. Chromatographia 51, 101–110 (2000).

A. Berthod, S. Carda-Broch, M.C. García-Álvarez-Coque, “Hydrophobicity of ionizable compounds: A theoretical study and measurements of diuretic octanol-water partition coefficients by countercurrent chromatography”. Analytical Chemistry 71, 879–888 (1999).

J.R. Torres-Lapasió, J.J. Baeza-Baeza, M.C. García-Álvarez-Coque, “Description of the retention behaviour in micellar liquid chromatography as a function of pH, surfactant and modifier concentration”. Journal of Chromatography A 769, 155–168 (1997).

J.S. Esteve-Romero, G. Ramis-Ramos, M.C. García-Álvarez-Coque, “Acid-base properties of azo dyes in the presence of surfactants”. Journal of Colloid and Interface Science 141, 44–49 (1991).

M.C. García, G. Ramis, C. Mongay, “Spectrophotometric determination of protonation constants of monoprotic systems in strong acid and strong basic media”. Spectrochimica Acta 38A, 1005–1009 (1982).