Basic compounds

E. Peris-García, R. Burgos-Gil, M.J. Ruiz-Ángel, M.C. García-Álvarez-Coque, “Hydrophilic liquid chromatography versus reversed-phase liquid chromatography in the absence and presence of 1‑hexyl-3-methylimidazolium chloride for the analysis of basic compounds”, Separations (Open Access) 79, 30 (2020).

N. Pankajkumar-Patel, E. Peris-García, M.J. Ruiz-Ángel, S. Carda-Broch, M.C. García-Álvarez-Coque, “Comparison of surfactant-mediated liquid chromatographic modes with sodium dodecyl sulphate for the analysis of basic drugs”. Analytical Methods 12, 2443‒2452 (2020).

O. Mompó-Roselló, A. Ribera-Castelló, E.F. Simó-Alfonso, M.J. Ruiz-Ángel, M.C. García-Álvarez-Coque, J.M. Herrero-Martínez, “Extraction of β-blockers from urine with a polymeric monolith modified with 1-allyl-3-methylimidazolium chloride in spin column format”. Talanta 214, 120860 (2020).

R. Burgos-Gil, E. Peris-García, M.J. Ruiz-Ángel, J.J. Baeza-Baeza, M.C. García-Álvarez-Coque, “Protocol to compare column performance applied to hydrophilic interaction liquid chromatography”. Microchemical Journal 149, 103973 (2019).

E. Peris-García, M.C. García-Álvarez-Coque, S. Carda-Broch, M.J. Ruiz-Ángel, “Effect of buffer nature and concentration on the chromatographic performance of basic compounds in the absence and presence of 1-hexyl-3-methylimidazolium chloride”. Journal of Chromatography A 1602, 397–408 (2019).

S. Carda-Broch, M.C. García-Álvarez-Coque, M.J. Ruiz-Ángel, ”Extent of the influence of phosphate buffer and ionic liquids on the reduction of the silanol effect in a C18 stationary phase”. Journal of Chromatography A 1559, 112–117 (2018).

S. Calabuig-Hernández, E. Peris-García, M.C. García-Álvarez-Coque, M.J. Ruiz-Ángel, “Suitability of 1-hexyl-3-methylimidazolium ionic liquids for the analysis of pharmaceutical formulations containing tricyclic antidepressants”. Journal of Chromatography A 1559, 118–127 (2018).

E. Peris-García, M.J. Ruiz-Ángel, S. Carda-Broch, M.C. García-Álvarez-Coque, “Analysis of basic drugs by liquid chromatography with environmentally friendly mobile phases in pharmaceutical formulations”. Microchemical Journal 134, 202–210 (2017).

S. Calabuig-Hernández, M.C. García-Álvarez-Coque, M.J. Ruiz-Ángel, “Performance of amines as silanol suppressors in reversed-phase liquid chromatography”. Journal of Chromatography A 1465, 98–106 (2016).

M.J. Ruiz-Ángel, E. Peris-García, M.C. García-Álvarez-Coque, “Reversed-phase liquid chromatography with mixed micellar mobile phases of Brij-35 and sodium dodecyl sulphate: A method for the analysis of basic compounds”. Green Chemistry 17, 3561–3570 (2015).

M.T. Úbeda-Torres, C. Ortiz-Bolsico, M.C. García-Álvarez-Coque, M.J. Ruiz-Ángel, “Gaining insight in the behaviour of imidazolium-based ionic liquids as additives in reversed-phase liquid chromatography for the analysis of basic compounds”. Journal of Chromatography A 1380, 96–103 (2015).

M.C. García-Álvarez-Coque, G. Ramis-Ramos, M.J. Ruiz-Ángel, “Liquid chromatography, ion pair chromatography”. Reference Module in Chemistry, Molecular Sciences and Chemical Engineering Series (edited by J. Reedijk), Elsevier, Waltham, MA (2015). ISBN: 978-0-12-409547-2; DOI: 10.1016/B978-0-12-409547-2.11687-7.

M.J. Ruiz-Ángel, S. Pous-Torres, S. Carda-Broch, M.C. García-Álvarez-Coque, “Performance of different C18 columns in reversed-phase liquid chromatography with hydro-organic and micellar-organic mobile phases”. Journal of Chromatography A 1344, 76–82 (2014).

J.J. Baeza-Baeza, M.J. Ruiz-Ángel, S. Carda-Broch, M.C. García-Álvarez-Coque, “Half-width plots, a simple tool to predict peak shape, reveal column kinetics and characterise chromatographic columns in liquid chromatography: State of the art and new results”. Journal of Chromatography A 1314, 142–153 (2013).

M.J. Ruiz-Ángel, S. Carda-Broch, M.C. García-Álvarez-Coque, “Chromatographic efficiency in micellar liquid chromatography: should it be still a topic of concern?”. Separation and Purification Reviews 42, 1–27 (2013).

S. Pous-Torres, J.R. Torres-Lapasió, M.C. García-Álvarez-Coque, “Comparison of the performance of Chromolith Performance RP-18e, 1.8μm Zorbax Eclipse XDB-C18 and XTerra MS C18, based on modelling approaches”. Analytical and Bioanalytical Chemistry 405, 2219–2231 (2013).

J.J. Fernández-Navarro, J.R. Torres-Lapasió, M.J. Ruiz-Ángel, M.C. García-Álvarez-Coque, “1‑Hexyl-3-methyl imidazolium tetrafluoroborate: An efficient column enhancer in the separation of basic drugs by reversed-phase liquid chromatography”. Journal of Chromatography A 1258, 168―174 (2012).

J.J. Fernández Navarro, J.R. Torres-Lapasió, M.J. Ruiz-Ángel, M.C. García-Álvarez-Coque, “Silanol suppressing potency of alkyl-imidazolium ionic liquids on C18 stationary phases”. Journal of Chromatography A 1232, 166–175 (2012).

J.J. Fernández Navarro, M.C. García-Álvarez-Coque, M.J. Ruiz-Ángel, “The role of the dual nature of ionic liquids in the reversed-phase liquid chromatographic separation of basic drugs”. Journal of Chromatography A 1218, 398–407 (2011).

M.J. Ruiz-Ángel, M.C. García-Álvarez-Coque, “Comparison of the performance of non-ionic and anionic surfactant as mobile phase additives in the RPLC analysis of basic drugs”. Journal of Separation Science 34, 623–630 (2011).

M.C. García-Álvarez-Coque, M.J. Ruiz-Ángel, “Reliable measurement of silanol suppression potency in alkyl-bonded stationary phases”. LCGC’ The Column (digital journal, Ed. Advanstar Communications, ISSN 2050-280X), 7, 2–8 (2011).

M.J. Ruiz-Ángel, J.R. Torres-Lapasió, S. Carda-Broch, M.C. García-Álvarez-Coque, “Performance of short-chain alcohols versus acetonitrile in the surfactant-mediated reversed-phase liquid chromatographic separation of β-blockers”. Journal of Chromatography A 1217, 7090–7099 (2010).

M.J. Ruiz-Ángel, S. Carda-Broch, M.C. García-Álvarez-Coque, “Effect of short-chain alcohols on surfactant-mediated reversed-phase liquid chromatographic systems”. Journal of Chromatography A 1217, 7082–7089 (2010).

M.J. Ruiz-Ángel, S. Carda-Broch, M.C. García-Álvarez-Coque, “Peak half-width plots to study the effect of organic solvents on the peak performance of basic drugs in micellar liquid chromatography”. Journal of Chromatography A 1217, 1786–1798 (2010).

M.J. Ruiz-Ángel, J.R. Torres-Lapasió, M.C. García-Álvarez-Coque, S. Carda-Broch, “Submicellar and micellar reversed-phase liquid chromatographic modes applied to the separation of β-blockers”. Journal of Chromatography A 1216, 3199–3209 (2009).

M.J. Ruiz-Ángel, J.R. Torres-Lapasió, M.C. García-Álvarez-Coque, S. Carda-Broch, “Retention mechanisms for basic drugs in the submicellar and micellar reversed-phase liquid chromatographic modes”. Analytical Chemistry 80, 9705–9713 (2008).

S. Pous-Torres, J.R. Torres-Lapasió, M.J. Ruiz-Ángel, M.C. García-Álvarez-Coque, “Interpretive optimisation of organic solvent content and flow-rate in the separation of β‑blockers with a Chromolith RP–18e column”. Journal of Separation Science 32, 2793–2803 (2009).

S. Pous-Torres, M.J. Ruiz-Ángel, J.R. Torres-Lapasió, M.C. García-Álvarez-Coque, “Performance of a Chromolith RP-18e column for the screening of β‑blockers”. Journal of Separation Science 32, 2841–2853 (2009).

M.J. Ruiz-Ángel, S. Carda-Broch, A. Berthod, “Ionic liquids versus triethyilamine as mobile phase additives in the analysis of β-blockers”. Journal of Chromatography A 1119, 202–208 (2006).

R. Ruiz, M.J. Ruiz-Ángel, M.C. García-Álvarez-Coque, C. Ràfols, M. Rosés, E. Bosch, “Hydrophobic and cation exchange mechanisms in the retention of basic compounds in a polymeric column”. Journal of Chromatography A 1028, 139–148 (2004).

S. Carda-Broch, A. Berthod, “pH dependence of the hydrophobicity of β-blocker amine compounds measured by counter-current chromatography”. Journal of Chromatography A 995, 55–66 (2003).

M.J. Ruiz-Ángel, J.R. Torres-Lapasió, S. Carda-Broch, M.C. García-Álvarez-Coque, “Improvement of peak shape and separation performance of β-blockers in conventional reversed-phase columns using solvent modifiers”. Journal of Chromatographic Science 41, 350–358 (2003).

M.J. Ruiz-Ángel, S. Carda-Broch, J.R. Torres-Lapasió, E.F. Simó-Alfonso, M.C. García-Álvarez-Coque, “Micellar-organic versus aqueous-organic mobile phases for the screening of β-blockers”. Analytica Chimica Acta 454, 109–123 (2002).

A. Detroyer, Y. vander Heyden, S. Carda-Broch, M.C. García-Álvarez-Coque, D.L. Massart, “Quantitative structure-retention and retention-activity relationships of β-blocking agents by micellar liquid chromatography”. Journal of Chromatography A 912, 211–221 (2001).

M. Gil-Agustí, J.R. Torres-Lapasió, M.C. García-Álvarez-Coque, J. Esteve-Romero, “Comparison of the performance of butanol and pentanol as modifiers in the micellar liquid chromatographic determination of some phenethylamines”. Journal of Chromatography A 866, 35–49 (2000).

I. Rapado-Martínez, R.M. Villanueva-Camañas, M.C. García-Álvarez-Coque, “Micellar liquid chromatography: A worthy technique for the determination of b-antagonists in urine samples”. Analytical Chemistry 71, 319–326 (1999).

I. Rapado-Martínez, M.C. García-Álvarez-Coque, R.M. Villanueva-Camañas, “Liquid chromatographic procedure for the evaluation of β-blockers in pharmaceuticals using hybrid micellar mobile phases”. Journal of Chromatography A 765, 221–231 (1997).

I. Rapado-Martínez, M.C. García-Álvarez-Coque, R.M. Villanueva-Camañas, “Performance of micellar mobile phases in reversed-phase chromatography for the analysis of pharmaceuticals containing β-blockers and other antihypertensive drugs”. Analyst 121, 1677–1682 (1996).