Embedded Files
1. Pau Peiró Vila
2. Carlos Josué Tereba-Mamani
3. Adrián Gisbert-Alonso
4. Nikitaben Pankajkumar-Patel
5. José Antonio Navarro-Huerta
6. Ester Peris-García
7. Tamara Álvarez-Segura
8. Sergio Marco-Peiró
9. Casandra Ortiz-Bolsico
10. Inmaculada Casas-Breva
11. Alberto Ortín-Sebastián
12. Juan José Fernández-Navarro
13. Beatriz Beltrán-Martinavarro
14. María Rambla-Alegre
15. Sandra Pous-Torres
16. Victoria Concha Herrera
17. Gabriel Vivó Truyols
18. María Elisa Capella-Peiró
19. María José Ruiz-Ángel
20. Mayte Gil-Agustí
21. Rosendo David Caballero
22. Luis Álvarez-Rodríguez
23. Sagrario Torres-Cartas
24. Sergio López-Grío
25. Samuel Carda-Broch
26. Inmaculada Rapado-Martínez
27. José Ramón Torres-Lapasió
28. Yolanda Martín-Biosca
29. Llorenç Monferrer-Pons
30. Emilio Bonet-Domingo
31. María Ángeles Rius-Revert
32. Ernesto Francisco Simó-Alfonso
33. María José Medina-Hernández
Pau Peiró Vila
(from University of Valencia, Spain)
"Estrategias para mejorar la calidad de las separaciones de muestras complejas en cromatografía líquida"
Supervisors: José Ramón Torres-Lapasió and María Celia García-Álvarez-Coque
University of Valencia (Spain), start in September 2022.
Master in "Chemistry" at University of Valencia, June 2021.
Carlos Josué Tereba-Mamani
(from University of Valencia, Spain)
"Studies to increase the performance and sustainability in reversed-phase liquid chromatography"
Supervisors: María Celia García-Álvarez-Coque and María José Ruiz Ángel
University of Valencia (Spain), start in September 2021.
Master in "Experimental in Chemistry" at University of Valencia, June 2021.
Adrián Gisbert-Alonso
(from University of Valencia, Spain)
"Development of new strategies in liquid chromatography for the analysis of complex samples"
Supervisors: José Ramón Torres-Lapasió and María Celia García-Álvarez-Coque
University of Valencia (Spain), start in September 2019.
Master in "Experimental Techniques in Chemistry" at University of Valencia, June 2019.
A. Gisbert-Alonso, A. Navarro-Martínez, J.A. Navarro-Huerta, J.R. Torres-Lapasió, M.C. García-Álvarez-Coque, “Global modelling of retention for the interpretive optimization of the resolution of fingerprints for the analysis of medicinal herbs”. Journal of Chromatography A (sent October 2021).
A. Gisbert-Alonso, J.A. Navarro-Huerta, J.R. Torres-Lapasió, M.C. García-Álvarez-Coque, “Global retention models and their application to the prediction of chromatographic fingerprints”. Journal of Chromatography A 1637, 461845 (2021).
A. Gisbert-Alonso, J.A. Navarro-Huerta, J.R. Torres-Lapasió, M.C. García-Álvarez-Coque, “Testing experimental designs in liquid chromatography (II): Influence of the design geometry on the prediction performance of retention models”. Journal of Chromatography A 1654, 462458 (2021).
J.A. Navarro-Huerta, A. Gisbert-Alonso, J.R. Torres-Lapasió, M.C. García-Álvarez-Coque, “Testing experimental designs in liquid chromatography (I): Development and validation of a method for the comprehensive inspection of experimental designs”. Journal of Chromatography A 1624, 461180 (2020).
J.A. Navarro-Huerta, A. Gisbert-Alonso, J.R. Torres-Lapasió, M.C. García-Álvarez-Coque, “Benefits of solvent concentration pulses in retention time modelling of liquid chromatography”. Journal of Chromatography A 1597, 76‒88 (2019).
Nikitaben Pankajkumar Patel
(from Sardar Patel University, Vallabh Vidhyanagar, Gujarat, India)
"Development of methods in microemulsion liquid chromatography"
Supervisors: María Celia García-Álvarez-Coque and María José Ruiz-Ángel
University of Valencia (Spain), July 2021.
Master in "Analytical Chemistry" in Sardar Patel University, Vallabh Vidhyanagar, Gujarat (India).
N. Pankajkumar-Patel, E. Peris-García, M.J. Ruiz-Ángel, M.C. García-Álvarez-Coque, “Microemulsion liquid chromatography with imidazolium ionic liquid”. Journal of Chromatography A (sent October 2021).
N. Pankajkumar-Patel, E. Peris-García, M.J. Ruiz-Ángel, M.C. García-Álvarez-Coque, “Analysis of tricyclic antidepressants in pharmaceuticals by microemulsion liquid chromatography”, Microchemical Journal 160, 105659 (2021).
N. Pankajkumar-Patel, E. Peris-García, O. Schiopu, M.J. Ruiz-Ángel, J.J. Baeza-Baeza, M.C. García-Álvarez-Coque, “Performance and modelling of retention in microemulsion liquid chromatography”. Journal of Chromatography A 1634, 461651 (2020).
N. Pankajkumar-Patel, E. Peris-García, M.J. Ruiz-Ángel, S. Carda-Broch, M.C. García-Álvarez-Coque, “Comparison of surfactant-mediated liquid chromatographic modes with sodium dodecyl sulphate for the analysis of basic drugs”. Analytical Methods 12, 2443‒2452 (2020).
E. Peris-García, N. Pankajkumar-Patel, S. Carda-Broch, M.J. Ruiz-Ángel, M.C. García-Álvarez-Coque, ”Oil-in-water microemulsion liquid chromatography” (review). Separation and Purification Reviews 49, 89–111 (2020).
N. Pankajkumar-Patel, E. Peris-García, M.J. Ruiz-Ángel, S. Carda-Broch, M.C. García-Álvarez-Coque, “Modulation of retention and selectivity in oil-in-water microemulsion liquid chromatography”. Journal of Chromatography A 1592, 91–100 (2019).
José Antonio Navarro Huerta
(from University of Valencia, Spain)
"Design of optimisation strategies in liquid chromatography”
Supervisors: María Celia García-Álvarez-Coque and José Ramón Torres-Lapasió
University of Valencia (Spain), July 2021.
Master in "Experimental Techniques in Chemistry" at University of Valencia July 2016.
PhD grant, PROMETEO Project, Generalitat Valenciana, University of Valencia (December 2017–December 2018).
PhD grant, Talent attraction, University of Valencia (January 2019–March 2021).
Post-doc researcher, Novartis Pharma AG, Department of Chemical and Analytical Development, Basilea (Switzerland), start September 2021.
M.C. García-Álvarez-Coque, J.A. Navarro-Huerta, M.J. Ruiz-Ángel, J.R. Torres-Lapasió, “Secondary chemical equilibria in reversed-phase liquid chromatography”. Liquid Chromatography: Fundamentals and Instrumentation (edited by B. Chankvetadze, S. Fanali, P. Haddad, C.F. Poole, M.L. Riekkola), 3rd ed. (2022), Elsevier, Amsterdam.
M.C. García-Álvarez-Coque, J.A. Navarro-Huerta, M.J. Ruiz-Ángel, J.R. Torres-Lapasió, “Secondary chemical equilibria in reversed-phase liquid chromatography”. Liquid Chromatography: Fundamentals and Instrumentation (edited by B. Chankvetadze, S. Fanali, P. Haddad, C.F. Poole, M.L. Riekkola), 3rd ed. (2022), Elsevier, Amsterdam.
A. Gisbert-Alonso, A. Navarro-Martínez, J.A. Navarro-Huerta, J.R. Torres-Lapasió, M.C. García-Álvarez-Coque, “Global modelling of retention for the interpretive optimization of the resolution of fingerprints for the analysis of medicinal herbs”. Journal of Chromatography A (sent October 2021).
A. Gisbert-Alonso, J.A. Navarro-Huerta, J.R. Torres-Lapasió, M.C. García-Álvarez-Coque, “Testing experimental designs in liquid chromatography (II): Influence of the design geometry on the prediction performance of retention models”. Journal of Chromatography A 1654, 462458 (2021).
A. Gisbert-Alonso, J.A. Navarro-Huerta, J.R. Torres-Lapasió, M.C. García-Álvarez-Coque, “Global retention models and their application to the prediction of chromatographic fingerprints”. Journal of Chromatography A 1637, 461845 (2021).
J.A. Navarro-Huerta, A. Gisbert-Alonso, J.R. Torres-Lapasió, M.C. García-Álvarez-Coque, “Testing experimental designs in liquid chromatography (I): Development and validation of a method for the comprehensive inspection of experimental designs”. Journal of Chromatography A 1624, 461180 (2020).
M. Vergara-Barberán, J.A. Navarro-Huerta, J.R. Torres-Lapasió, E.F. Simó-Alfonso, M.C. García-Álvarez-Coque, “Classification of olive leaves and pulp extracts by comprehensive two-dimensional liquid chromatography of polyphenolic fingerprints”. Food Chemistry 320, 126630 (2020).
J.A. Navarro-Huerta, A.G. Vargas-García, J.R. Torres-Lapasió, M.C. García-Álvarez-Coque, “Interpretive search of optimal isocratic and gradient separations in micellar liquid chromatography in extended organic solvent domains”. Journal of Chromatography A 1616, 460784 (2020).
J.A. Navarro Huerta, E.J. Carrasco Correa, J.R. Torres Lapasió, J.M. Herrero Martínez, M.C. García Álvarez-Coque, “Modelling retention and peak shape of small polar solutes analysed by nano-HPLC using methacrylate monolithic columns”. Analytica Chimica Acta 1086, 142–155 (2018).
J.A. Navarro-Huerta, A. Gisbert-Alonso, J.R. Torres-Lapasió, M.C. García-Álvarez-Coque, “Benefits of solvent concentration pulses in retention time modelling of liquid chromatography”. Journal of Chromatography A 1597, 76–88 (2019).
J.A. Navarro-Huerta, J.R. Torres-Lapasió, M.C. García-Álvarez-Coque, “Estimation of peak capacity based on peak simulation”. Journal of Chromatography A 1574, 101–113 (2018).
M.C. García-Álvarez-Coque, J.R. Torres-Lapasió, J.A. Navarro-Huerta, “Secondary chemical equilibria in reversed-phase liquid chromatography”. Liquid Chromatography: Fundamentals and Instrumentation, 2nd edition (edited by S. Fanali, P. Haddad, C. Poole, M.L. Riekkola), Chapter 5 (pp. 125–146. Elsevier, Amsterdam (2017). ISBN: 978-0-12-805393-5.
G. Ramis-Ramos, M.C. García-Álvarez-Coque, J.A. Navarro-Huerta, “Solvent selection in liquid chromatography”. Liquid Chromatography: Fundamentals and Instrumentation, 2nd edition (edited by S. Fanali, P. Haddad, C. Poole, M.L.Riekkola), Chapter 13 (pp. 343–373. Elsevier, Amsterdam (2017). ISBN: 978-0-12-805393-5.
J.A. Navarro-Huerta, T. Álvarez-Segura, J.R. Torres-Lapasió, M.C. García-Álvarez-Coque, “Study of the performance of a resolution criterion to characterise complex chromatograms with unknowns or without standards”. Analytical Methods 9, 4293–4303 (2017).
J.A. Navarro-Huerta, J.R. Torres-Lapasió, S. López-Ureña, M.C. García-Álvarez-Coque, “Assisted baseline subtraction in complex chromatograms using the BEADS algorithm”. Journal of Chromatography A 1507, 1–10 (2017).
Ester Peris-García
(from University of Valencia, Spain)
"Widening the possibilities of liquid chromatography through the use of secondary equilibria with additives and hydrophilic interaction chromatography”
Supervisors: María Celia-García Álvarez-Coque, María José Ruiz Ángel and Samuel Carda-Broch
University of Valencia (Spain), November 2019.
Master in "Experimental Techniques in Chemistry" at the University od Valencia, June 2014.
PhD grant, Talent attraction, University of Valencia (June 2016–November 2019).
PhD grant, Talent attraction, University of Valencia (December 2019–November 2020).
Innovation Projects Technician, Parque Científico Tecnológico y Empresarial (ESPAITEC), University Jaume I, Castellón, Spain.
N. Pankajkumar-Patel, E. Peris-García, M.J. Ruiz-Ángel, M.C. García-Álvarez-Coque, “Microemulsion liquid chromatography with imidazolium ionic liquid”. Journal of Chromatography A (sent October 2021).
E. Peris-García, M.J. Ruiz-Ángel, J.J. Baeza-Baeza, M.C. García-Álvarez-Coque, “Comparison of the fitting performance of retention models and elution strength behaviour in hydrophilic-interaction and reversed-phase liquid chromatography”, Separations 8, 54 (2021).
N. Pankajkumar-Patel, E. Peris-García, M.J. Ruiz-Ángel, M.C. García-Álvarez-Coque, “Analysis of tricyclic antidepressants in pharmaceuticals by microemulsion liquid chromatography”, Microchemical Journal 160, 105659 (2021).
N. Pankajkumar-Patel, E. Peris-García, O. Schiopu, M.J. Ruiz-Ángel, J.J. Baeza-Baeza, M.C. García-Álvarez-Coque, “Performance and modelling of retention in microemulsion liquid chromatography”. Journal of Chromatography A 1634, 461651 (2020).
E. Peris-García, R. Burgos-Gil, M.J. Ruiz-Ángel, M.C. García-Álvarez-Coque, “Hydrophilic liquid chromatography versus reversed-phase liquid chromatography in the absence and presence of 1‑hexyl-3-methylimidazolium chloride for the analysis of basic compounds”. Separations (open access) 7, 30 (2020).
N. Pankajkumar-Patel, E. Peris-García, M.J. Ruiz-Ángel, M.C. García-Álvarez-Coque, “Comparison of surfactant-mediated liquid chromatographic modes with sodium dodecyl sulphate for the analysis of basic drugs”. Analytical Methods 12, 2443‒2452 (2020).
E. Peris-García, N. Pankajkumar-Patel, M.J. Ruiz-Ángel, S. Carda-Broch, M.C. García-Álvarez-Coque, “Oil-in-water microemulsion liquid chromatography”. Separation and Purification Reviews 49, 89‒111 (2020).
R. Burgos-Gil, E. Peris-García, M.J. Ruiz-Ángel, J.J. Baeza-Baeza, M.C. García-Álvarez-Coque, “Protocol to compare column performance applied to hydrophilic interaction liquid chromatography”. Microchemical Journal 149, 103973 (2019).
E. Peris-García, M.C. García-Álvarez-Coque, S. Carda-Broch, M.J. Ruiz-Ángel, “Effect of buffer nature and concentration on the chromatographic performance of basic compounds in the absence and presence of 1-hexyl-3-methylimidazolium chloride”. Journal of Chromatography 1602, 397–408 (2019).
N. Pankajkumar-Patel, E. Peris-García, M.J. Ruiz-Ángel, S. Carda-Broch, M.C. García-Álvarez-Coque, “Modulation of retention and selectivity in oil-in-water microemulsion liquid chromatography”. Journal of Chromatography A 1592, 91–100 (2019).
M.C. García-Álvarez-Coque, M.J. Ruiz-Ángel, E. Peris-García, “Micellar liquid chromatography”. Encyclopedia of Analytical Chemistry (edited by P.J. Worsfold, A. Townshend, C. Poole, M. Miró), Vol. 6 (pp. 133–142). Elsevier, Waltham, MA (2019). ISBN: 978-0-0810-1983-2. Also in Reference Module in Chemistry, Molecular Sciences and Chemical Engineering Series (edited by J. Reedijk).
J. Rodríguez-Martínez, J.J. Baeza-Baeza, M.C. García-Álvarez-Coque, M.J. Ruiz- Ángel, ”Search of new non-ionic surfactants for micellar liquid chromatography”. Analytical and Bioanalytical Chemistry 410, 5043–5057 (2018).
S. Calabuig-Hernández, E. Peris-García, M.C. García-Álvarez-Coque, M.J. Ruiz-Ángel, ”Suitability of 1-hexyl-3-methylimidazolium ionic liquids for the analysis of pharmaceutical formulations containing tricyclic antidepressants”. Journal of Chromatography A 1559, 118–127 (2018).
E. Peris-García, M.J. Ruiz-Ángel, S. Carda-Broch, M.C. García-Álvarez-Coque, “Analysis of basic drugs by liquid chromatography with environmentally friendly mobile phases in pharmaceutical formulations”. Microchemical Journal 134, 202–210 (2017).
E. Peris-García, M.T. Úbeda-Torres, M.J. Ruiz-Ángel, M.C. García-Álvarez-Coque, “Effect of sodium dodecyl sulphate and Brij-35 on the analysis of sulphonamides in physiological samples using direct injection and acetonitrile gradients”. Analytical Methods 8, 3941–3952 (2016).
E. Peris-García, C. Ortiz-Bolsico, J.J. Baeza-Baeza, M.C. García-Álvarez-Coque, “Isocratic and gradient elution in micellar liquid chromatography with Brij-35”. Journal of Separation Science 38, 2059–2067 (2015).
M.J. Ruiz-Ángel, E. Peris-García, M.C. García-Álvarez-Coque, “Reversed-phase liquid chromatography with mixed micellar mobile phases of Brij-35 and sodium dodecyl sulphate: a method for the analysis of basic compounds”. Green Chemistry 17, 3561–3570 (2015).
Tamara Álvarez-Segura
(from University of Valencia, Spain)
"Multi-column strategies to increase the resolution of complex samples”
Supervisors: María Celia-García Álvarez-Coque and José Ramón Torres-Lapasió
University of Valencia (Spain), start in September 2014
Master in "Experimental Techniques in Chemistry", June 2014.
PhD grant, Val+i+d Generalitat Valenciana (January 2016-May 2016
PhD grant. Talent Attraction, University of Valencia (June 2016-December 2019)
Post-doc grant. Talent Attraction, University of Valencia (February-October 2019)
Post-doc technician, La Fe Hospital, Fundació Investigació Sanitària, Valencia, October 2019-May 2021
S. López-Ureña, J.R. Torres-Lapasió, T. Álvarez-Segura, M.C. García Álvarez-Coque, “Multi-scale Optimisation vs. Genetic Algorithms in the separation of diuretics by Reversed-Phase Liquid Chromatography”. Journal of Chromatography A 1609, 460427 (2020).
T. Álvarez-Segura, E. Cabo-Calvet, J.J. Baeza-Baeza, M.C. García-Álvarez-Coque, “Study of the efficiency using gradient elution based on Van Deemter plots”. Journal of Chromatography 1584, 126–13413 (2019).
T. Álvarez Segura, X. Subirats, M. Rosés, Retention-pH profiles of acids and bases in hydrophilic interaction liquid chromatography. Analytica Chimica Acta 1050, 176‒184 (2019).
T. Álvarez-Segura, J.R. Torres-Lapasió, M.C. García-Álvarez-Coque, ”Updating chromatographic predictions by accounting ageing for single and serially-coupled columns”. Journal of Separation Science 41, 2719–2730 (2018).
T. Álvarez-Segura, C. Camacho-Molinero, J.R. Torres-Lapasió, M.C. García-Álvarez-Coque, “Analysis of amino acids using serially-coupled columns”. Journal of Separation Science 40, 2741–2751 (2017).
J.A. Navarro-Huerta, T. Álvarez-Segura, J.R. Torres-Lapasió, M.C. García-Álvarez-Coque, “Study of the performance of a resolution criterion to characterise complex chromatograms with unknowns or without standards”. Analytical Methods 9, 4293–4303 (2017).
T. Álvarez-Segura, M.D. Peris-Díaz, M.C. García-Álvarez-Coque, J.J. Baeza-Baeza, "New approaches to evaluate the dispersion parameters in liquid chromatography based on the information obtained from a set of compounds”. Current Chromatography 4, 156‒166 (2017).
T. Álvarez-Segura, J.R. Torres-Lapasió, M.C. García-Álvarez-Coque, “Optimisation of chromatographic resolution using objective functions including both time and spectral information. Part 2: Compounds exhibiting small spectral differences”. Current Chromatography 3, 34–43 (2016).
T. Álvarez-Segura, J.R. Torres-Lapasió, C. Ortiz-Bolsico, M.C. García-Álvarez-Coque, “Stationary phase modulation in liquid chromatography through the serial coupling of columns” (review). Analytica Chimica Acta 923, 1–23 (2016).
T. Álvarez-Segura, E. Cabo-Calvet, J.R. Torres-Lapasió, M.C. García-Álvarez-Coque, “An approach to evaluate the information in chromatographic fingerprints: Application to the optimisation of the extraction and conservation conditions of medicinal herbs”. Journal of Chromatography A 1422, 178–185 (2015).
T. Álvarez-Segura, C. Ortiz-Bolsico, J.R. Torres-Lapasió, M.C. García-Álvarez-Coque, “Serial versus parallel columns using isocratic elution: A comparison of multi-column approaches in mono-dimensional liquid chromatography”. Journal of Chromatography A 1390, 95–102 (2015).
T. Álvarez-Segura, M.C. García-Álvarez-Coque, C. Ortiz-Bolsico, J.R. Torres-Lapasió, “Interpretive approaches to optimize serially-coupled columns in reversed-phase liquid chromatography”. Current Chromatography 2,110–121 (2015).
T. Álvarez-Segura, A. Gómez-Díaz, C. Ortiz-Bolsico, J.R. Torres-Lapasió, M.C. García-Álvarez-Coque, “A chromatographic objective function to characterise chromatograms with unknown compounds or without standards available”. Journal of Chromatography A 1409, 79–88 (2015).
Sergio Marco-Peiró
(from University Jaume I, Castellón, Spain)
"Analytical applications of micellar liquid chromatography in Health Sciences”
Supervisors: Samuel Carda-Broch, Josep Esteve-Romero, Juan Peris-Vicente
University Jaume I (Castellón, Spain), May 2015.
Titular pharmacist in a pharmacy in Castellón, Spain
President of the Official College of Pharmaxists in Castellón, Spain
N. Agrawal, S. Marco-Peiró, J. Esteve-Romero, A. Durgbanshi, D. Bose, J. Peris-Vicente, S. Carda-Broch, “Determination of paroxetine in blood and urine using micellar liquid chromatography with electrochemical detection”. Journal of Chromatographic Science 52, 1217–1223 (2014).
B. Beltrán-Martinavarro, J. Peris-Vicente, M. Rambla-Alegre, S. Marco-Peiró, J. Esteve-Romero, S. Carda-Broch, “Quantification of melamine in drinking and wastewater by micellar liquid chromatography”, Journal of AOAC (Association of Official Analytical Chemists) International 96, 870–874 (2013).
J. Peris-Vicente, S. Carda-Broch, J. Esteve-Romero, M. Rambla-Alegre, D. Bose, B. Beltrán-Martinavarro, S. Marco-Peiró, A. Martinavarro-Domínguez, E. Ochoa-Aranda, M.L. Chin-Chen, “Validation of micellar LC-based methods applied to analyze foodstuffs”, Bioanalysis 5, 481–494 (2013).
M.L. Chin-Chen, S. Carda-Broch, J. Peris-Vicente, M. Rambla-Alegre, J. Esteve-Romero, S. Marco-Peiro, “Evaluation of biogenic amines in fish sauce by derivatization with 3,5-dinitrobenzoyl chloride and micellar liquid chromatography”, Journal of Food Composition and Analysis 29, 32–36 (2013).
J. Esteve-Romero, S. Marco-Peiró, M. Rambla-Alegre, A. Durgbanshi, D. Bose, S.K. Mourya, “A micellar liquid chromatographic method for the determination of carbaryl and 1-naphthol in biological samples”, Journal of Liquid Chromatography and Related Technologies 35, 355–361 (2012).
S. Marco-Peiró, S. Beltrán-Martinavarro, M. Rambla-Alegre, J. Peris-Vicente, J. Esteve-Romero, “Validation of an analytical methodology to quantify melamine in body fluids using micellar liquid chromatography”, Talanta 88, 617–622 (2012).
B. Beltrán-Martinavarro, J. Peris-Vicente, S. Marco-Peiró, J. Esteve-Romero, M. Rambla-Alegre, S. Carda-Broch, “Use of micellar mobile phases for the chromatographic determination of melamine in dietetic supplements”, Analyst 137, 269–274 (2012).
M. Rambla-Alegre, S. Marco-Peiró, J. Peris-Vicente, B. Beltrán-Martinavarro, M.A. Collado. Sánchez, S. Carda-Broch, J. Esteve-Romero, “Analytical determination of hydroxytyrosol in olive extract samples by micellar liquid chromatography”, Food Chemistry 129, 614–618 (2011).
M. Rambla-Alegre, J. Peris-Vicente, S. Marco-Peiró, B. Beltrán-Martinavarro, J. Esteve-Romero, “Development of an analytical methodology to quantify melamine in milk using micellar liquid chromatography and validation according to EU Regulation 2002/654/EC”, Talanta 81, 894–900 (2010).
Casandra Ortiz-Bolsico
(from University of Valencia, Spain)
"Strategies to improve column performance in high-performance liquid chromatography”
Supervisors: María Celia-García Álvarez-Coque, José Ramón Torres-Lapasió and María José Ruiz Ángel
University of Valencia (Spain), July 2015.
Master in "Experimental Techniques in Chemistry", June 2011.
PhD grant, Ministerio de Innovación y Ciencia, September 2011–June 2014.
Analyst in “Aguas de Valencia” (Paterna, Valencia, Spain), July 2014–.
C. Ortiz-Bolsico, M.J. Ruiz-Ángel, M.C. García-Álvarez-Coque, “Adsorption of the anionic surfactant sodium dodecyl sulphate on a C18 column under micellar and high submicellar conditions". Journal of Separation Science 38, 550–555 (2015).
T. Álvarez-Segura, M.C. García-Álvarez-Coque, C. Ortiz-Bolsico, J.R. Torres-Lapasió, “Interpretive approaches to optimize serially-coupled columns in reversed-phase liquid chromatography”. Current Chromatography 2,110–121 (2015).
T. Álvarez-Segura, A. Gómez-Díaz, C. Ortiz-Bolsico, J.R. Torres-Lapasió, M.C. García-Álvarez-Coque, “A chromatographic objective function to characterise chromatograms with unknown compounds or without standards available”. Journal of Chromatography A 1409, 79–88 (2015).
M.T. Úbeda-Torres, C. Ortiz-Bolsico, M.C. García-Álvarez-Coque, M.J. Ruiz-Ángel, “Gaining insight in the behaviour of imidazolium-based ionic liquids as additives in reversed-phase liquid chromatography for the analysis of basic compounds”. Journal of Chromatography A 1380, 96–103 (2015).
J.R. Torres-Lapasió, S. Pous-Torres, C. Ortiz-Bolsico, M.C. García-Álvarez-Coque, “Optimisation of chromatographic resolution using objective functions including both time and spectral information”. Journal of Chromatography A 1377, 75–84 (2015).
M.C. García-Álvarez-Coque, G. Ramis Ramos, J.R. Torres-Lapasió, C. Ortiz Bolsico, "Modelling the chromatographic behaviour in RPLC". Analytical Separation Science Series (edited by J.L. Anderson, A. Berthod, A. Stalcup, V. Pino-Estévez), Volume 1 (Liquid Chromatography), Chapter 9, pp. 199–225, Wiley-VCH, New York (2015). ISBN: 978-3-527-33374-5.
C. Ortiz-Bolsico, J.R. Torres-Lapasió, M.C. García-Álvarez-Coque, “Optimisation of gradient elution with serially-coupled columns. Part II: Multi-linear gradients”. Journal of Chromatography A 1373, 51–60 (2014).
C. Ortiz-Bolsico, J.R. Torres-Lapasió, M.C. García-Álvarez-Coque, “Optimisation of gradient elution with serially-coupled columns. Part I: Single linear gradients”. Journal of Chromatography A 1350, 51–60 (2014).
J. Rodenas-Montano, C. Ortiz-Bolsico, M.J. Ruiz-Ángel, M.C. García-Álvarez-Coque, “Implementation of gradients of organic solvent in micellar liquid chromatography using DryLab®: Separation of basic compounds in urine samples”. Journal of Chromatography A 1344, 31–41 (2013).
E. Cabo-Calvet, C. Ortiz-Bolsico, J.J. Baeza-Baeza, M.C. García-Álvarez-Coque, “Description of the retention and peak profile for Chromolith columns in isocratic and gradient elution using mobile phase composition and flow rate as factors”. Chromatography (Open access) 1, 194–210 (2014).
J.J. Baeza-Baeza, C. Ortiz-Bolsico, M.C. García-Álvarez-Coque, “New approaches based on modified Gaussian models for the prediction of chromatographic peaks”. Analytica Chimica Acta, 758, 36–44 (2013).
C. Ortiz-Bolsico, J.R. Torres-Lapasió, M.C. García-Álvarez-Coque, “Simultaneous optimization of mobile phase composition, column nature and length to analyse complex samples using serially coupled columns”. Journal of Chromatography A 1317, 39-48 (2013).
J.J. Baeza-Baeza, C. Ortiz-Bolsico, J.R. Torres-Lapasió, M.C. García-Álvarez-Coque, “Approaches to model the retention and peak profile in linear gradient reversed-phase liquid chromatography”. Journal of Chromatography A 1284, 28–35 (2013).
C. Ortiz-Bolsico, J.R. Torres-Lapasió, M.J. Ruiz-Ángel, M.C. García-Álvarez-Coque, “Comparison of two serially-coupled column systems and optimization software in isocratic liquid chromatography for resolving complex mixtures”. Journal of Chromatography A 1281, 94–105 (2013).
C. Ortiz-Bolsico, J.R. Torres-Lapasió, M.C. García-Álvarez-Coque, “Approaches to find complementary separation conditions for resolving complex mixtures by high-performance liquid chromatography”. Journal of Chromatography A 1229, 180–189 (2012).
Inmaculada Casas-Breva
(from University Jaume I, Castellón, Spain)
"Analysis of drugs in plasma and serum used in AIDS treatment by micellar liquid chromatography”
Supervisors: Samuel Carda-Broch, Josep Esteve-Romero, Juan Peris-Vicente
University Jaume I (Castellón, Spain), May 2015.
Pharmacist in the Hospital de la Plana, Villarreal, Castellón, Spain
J. Peris-Vicente, M. Villarreal-Traver, I. Casas-Breva, S. Carda-Broch, J. Esteve-Romero, “Use of micellar liquid chromatography to analyze darunavir, ritonavir, emtricitabine, and tenofovir in plasma”. Journal of Separation Science 37, 2825–2832 (2014).
J. Peris-Vicente, M. Villarreal-Traver, I. Casas-Breva, S. Carda-Broch, J. Esteve-Romero, “A micellar liquid chromatography method for the quantification of abacavir, lamivudine and raltegravir in plasma”. Journal of Pharmaceutical and Biomedical Analysis 98, 351–355 (2014).
J. Peris-Vicente, I. Casas-Breva, P. Roca-Genovés, J. Esteve-Romero, “Application of micellar liquid chromatography for the determination of antitumoral and antiretroviral drugs in plasma”. Bioanalysis 6, 1975–1988 (2014).
I. Casas-Breva, J. Peris-Vicente, M. Rambla-Alegre, S. Carda-Broch, J. Esteve-Romero, “Monitoring of HAART regime antiretrovirals in serum of acquired immunodeficiency syndrome patients by micellar liquid chromatography”. Analyst 137, 4327–4334 (2012).
Mei Liang Chin-chen
(from University Jaume I, Castellón, Spain)
“Micellar liquid chromatography: a versatil technique for food analysis”
Supervisors: J. Esteve-Romero and S. Carda-Broch
University Jaume I, Castellón (Spain), October 2014
M.L. Chin-Chen, S. Carda-Broch, J. Peris-Vicente, M. Rambla-Alegre, J. Esteve-Romero, S. Marco-Peiró, “Evaluation of biogenic amines in fish sauce by derivatization with 3,5-dinitrobenzoyl chloride and micellar liquid chromatography”. Journal of Food Composition and Analysis 29, 32–36 (2013).
J. Peris-Vicente, S. Carda-Broch, J. Esteve-Romero, M. Rambla-Alegre, D. Bose, B. Beltrán-Martinavarro, S. Marco-Peiró, A. Martinavarro-Domínguez, E. Ochoa-Aranda, M.L. Chin-Chen, “Validation of micellar LC-based methods applied to analyze foodstuffs” (review). Bioanalysis 5, 481–494 (2013).
M.L. Chin Chen, S. Carda-Broch, D. Bose, J. Esteve-Romero, “Direct injection and determination of the active principles of spices using micellar liquid chromatography”. Food Chemistry 120, 915–920 (2010).
M.L. Chin Chen, M. Rambla-Alegre, A. Durgavanshi, D. Bose, J. Esteve-Romero, “Rapid and sensitive determination of nicotine in formulations and biological fluid using micellar liquid chromatography with electrochemical detection”. Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences 878, 2397–2402 (2010).
M.L. Chin-Chen, J. Esteve-Romero, S. Carda-Broch, “Determination of the insecticide imidacloprid in fruit juices using micellar liquid chromatography”. Journal of AOAC International 92, 1551–1556 (2009).
Alberto Ortín-Sebastián
(Telecommunications Engineer from Polytechnic University of Valencia, Spain)
“Improvements on the detection and data treatment in high-temperature separation techniques for the characterization of polyolefins”
Supervisors: María Celia García-Álvarez-Coque and José Ramón Torres-Lapasió
University of Valencia (Spain), April 2014
Engineer, Polymer Char (Paterna, Valencia, Spain) (August 1994–).
Master in "Experimental Techniques in Chemistry", September 2010.
A. Ortín, J. Montesinos, E. López, P. del Hierro, B. Monrabal, J.R. Torres-Lapasió, M.C. García-Álvarez-Coque, “Characterization of chemical composition along the molar mass distribution in polyolefin copolymers by GPC using a modern filter-based IR detector”. Macromolecular Symposia 330, 63–80 (2013).
L. Romero, A. Ortín, B. Monrabal, J.R. Torres-Lapasió, M.C. García-Álvarez-Coque, “A new calibration method for the accurate determination of ethylene content in ethylene-propylene copolymers by CRYSTEX-IR”. Macromolecular Symposia 312, 157–166 (2012).
A. Ortín, L. Romero, B. Monrabal, J.R. Torres-Lapasió, M.C. García-Álvarez-Coque, “Filter-based IR detectors for high temperature SEC analysis of polyolefins: calibration with a small number of standards and error analysis”. Journal of Chromatography A 1257, 66–73 (2012).
A. Ortín, P. del Hierro, W.W. Yau, “Chemical composition analysis of polyolefins by multiple detection GPC-IR5”. LCGC The Application Notebook, Junio, 2011.
A. Ortín, B. Monrabal, J. Montesinos, M.P. del Hierro, “Application of a multiple linear regression model to fixed bands IR detector data in GPC-IR analysis of polyolefins”. Macromolecular Symposia 282, 65–70 (2009).
A. Ortín, B. Monrabal, J. Sancho-Tello, “Development of an automated cross-fractionation apparatus, TREF-GPC, for a full characterization of the bivariate distribution of polyolefins”. Macromolecular Symposia 257, 13–28 (2007).
Beatriz Beltrán-Martinavarro
(from University Jaume I, Castellón, Spain)
"Chromatographic determination of melamine in food and physiological samples”
Supervisors: Josep Esteve-Romero and Samuel Carda-Broch
University of Valencia (Spain), April 2014
Pharmacist in a pharmacy, Castellón, Spain
B. Beltrán-Martinavarro, J. Peris-Vicente, S. Carda-Broch, J. Esteve-Romero, "Development and validation of a micellar liquid chromatography-based method to quantify melamine in swine kidney". Food Control 46, 168-173 (2014).
J. Peris-Vicente, S. Carda-Broch, J. Esteve-Romero, M. Rambla-Alegre, D. Bose, B. Beltrán-Martinavarro, S. Marco-Peiró, A. Martinavarro-Domínguez, E. Ochoa-Aranda, M.L. Chin-Chen, “Validation of micellar LC-based methods applied to analyze foodstuffs” (review). Bioanalysis 5, 481–494 (2013).
B. Beltrán-Martinavarro, J. Peris-Vicente, M. Rambla-Alegre, S. Marco-Peiró, J. Esteve-Romero, S. Carda-Broch, “Quantification of melamine in drinking water and wastewater by micellar liquid chromatography”. Journal of AOAC International 96, 870–874 (2013).
S. Marco-Peiró, B. Beltrán-Martinavarro, M. Rambla-Alegre, J. Peris-Vicente, J. Esteve-Romero, “Validation of an analytical methodology to quantify melamine in body fluids using micellar liquid chromatography”. Talanta 88, 617–622 (2012).
B. Beltrán-Martinavarro, J. Peris-Vicente, S. Marco-Peiró, J. Esteve-Romero, M. Rambla-Alegre, S. Carda‑Broch, “Use of micellar mobile phases for the chromatographic determination of melamine in dietetic supplements”. Analyst 137, 269–274 (2012).
M. Rambla-Alegre, S. Marco-Peiró, J. Peris-Vicente, B. Beltrán-Martinavarro, M.A. Collado-Sánchez, S. Carda-Broch, J. Esteve-Romero, “Analytical determination of hydroxytyrosol in olive extract samples by micellar liquid chromatography”. Food Chemistry 129, 614–618 (2011).
M. Rambla-Alegre, J. Peris-Vicente, S. Marco-Peiró, B. Beltrán-Martinavarro, J. Esteve-Romero, “Development of an analytical methodology to quantify melamine in milk using micellar liquid chromatography and validation according to EU Regulation 2002/654/EC”. Talanta 81, 894-900 (2010).
Juan José Fernández-Navarro
(from University of Valencia, Spain)
“Study of the effect of ionic liquids and surfactants on the chromatographic behaviour of basic drugs”
Supervisors: María Celia García-Álvarez-Coque and María José Ruiz-Ángel
University of Valencia (Spain), November 2012
Master in "Experimental Techniques in Chemistry", September 2010.
J.J. Fernández-Navarro, M.J. Ruiz-Ángel, M.C. García-Álvarez-Coque, “Reversed-phase liquid chromatography without organic solvent for determination of tricyclic antidepressants”. Journal of Separation Science 35, 1303–1309 (2012).
J.J. Fernández-Navarro, J.R. Torres-Lapasió, M.J. Ruiz-Ángel, M.C. García-Álvarez-Coque, “1‑Hexyl-3-methyl imidazolium tetrafluoroboratA: an efficient column enhancer in the separation of basic drugs by reversed-phase liquid chromatography”. Journal of Chromatography A 1258, 168–174 (2012).
J.J. Fernández-Navarro, J.R. Torres-Lapasió, M.J. Ruiz-Ángel, M.C. García-Álvarez-Coque, “Silanol suppressing potency of alkyl-imidazolium ionic liquids on C18 stationary phases”. Journal of Chromatography A 1232, 166–175 (2012).
J.J. Baeza-Baeza, Y. Dávila, J.J. Fernández-Navarro, M.C. García-Álvarez-Coque, “Measurement of the elution strength and peak shape enhancement at increasing modifier concentration and temperature in RPLC”. Analytical and Bioanalytical Chemistry 404, 2973–2984 (2012).
J.J. Fernández-Navarro, M.C. García-Álvarez-Coque, M.J. Ruiz-Ángel, “The role of the dual nature of ionic liquids in the reversed-phase liquid chromatographic separation of basic drugs”. Journal of Chromatography A 1218, 398–407 (2011).
María Rambla-Alegre
(from University Jaume I, Castellón, Spain)
"Determination of physico-chemical, chromatographic and analytical parameters of antibiotics by micellar liquid chromatography in physiological and food samples”
Supervisor. Josep Esteve-Romero and Samuel Carda-Broch
University Jaume I, Castellón (Spain), March 2011
PhD grant, Ministerio de Innovación y Ciencia (September 2007–July 2011)
Post-doctorate stay with Prof. Pat Sandra at the Research Institute for Chromatography, Kortrijk (Belgium), since July 2011, Research position at the Institute.
M. Rambla-Alegre, J. Esteve-Romero, S. Carda-Broch, “Is it really necessary to validate an analytical method or not? That is the question”. Journal of Chromatography A 1232,101–109 (2012).
B. Beltrán-Martinavarro, J. Peris-Vicente, S. Marco-Peiró, J. Esteve-Romero, M. Rambla-Alegre, S. Carda‑Broch, “Use of micellar mobile phases for the chromatographic determination of melamine in dietetic supplements”. Analyst 137, 269–274 (2012).
M. Rambla-Alegre, S. Carda-Broch, “Bioanalysis young investigator: Maria Rambla-Alegre”. Bioanalysis 4, 1159–1160 (2012).
M. Rambla-Alegre, R. Martí-Centelles, J. Esteve-Romero, S. Carda-Broch, “Application of a liquid chromatographic procedure for the analysis of penicillin antibiotics in biological fluids and pharmaceutical formulations using sodium dodecyl sulphate/propanol mobile phases and direct injection”. Journal of Chromatography A 1218, 4972–4981 (2011).
M. Rambla-Alegre, M.A. Collado-Sánchez, J. Esteve-Romero, S. Carda-Broch, “Quinolones control in milk and eggs samples by liquid chromatography using a surfactant-mediated mobile phase”. Analytical and Bioanalytical Chemistry 400, 1303–1313 (2011).
M. Rambla-Alegre, S. Marco-Peiró, J. Peris-Vicente, B. Beltrán-Martinavarro, M.A. Collado-Sánchez, S. Carda-Broch, J. Esteve-Romero, “Analytical determination of hydroxytyrosol in olive extract samples by micellar liquid chromatography”. Food Chemistry 129, 614–618 (2011).
M. Rambla-Alegre, J. Esteve-Romero, S. Carda-Broch, “Development and validation of micellar liquid chromatographic methods for the determination of antibiotics in different matrixes”. Journal of AOAC International 94, 775–785 (2011).
M. Rambla-Alegre, J. Peris Vicente, J. Esteve-Romero, S. Carda-Broch, “Analysis of selected veterinary antibiotics in fish by micellar liquid chromatography with fluorescence detection and validation in accordance with regulation 2002/657/EC”. Food Chemistry 123, 1294–1302 (2010).
M.A. Collado-Sánchez, M. Rambla-Alegre, S. Carda-Broch, J. Esteve-Romero, “Simultaneous separation and determination of quinolones in pharmaceuticals by micellar liquid chromatography”. Journal of Liquid Chromatography and Related Technologies 33, 513–525 (2010).
M. Rambla-Alegre, J. Esteve-Romero, S. Carda-Broch, “Analysis of omeprazole and its main metabolites by liquid chromatography using hybrid micellar mobile phases”. Analytical Chimica Acta 633, 250–256 (2009).
M. Rambla-Alegre, J. Esteve-Romero, S. Carda-Broch, “Validation of a MLC method with fluorescence detection for the determination of quinolones in urine samples by direct injection”. Journal of Chromatography B 877, 3975–3981 (2009).
M. Rambla-Alegre, S. Carda-Broch, J. Esteve-Romero, “Column classification and selection for the determination of antibiotics by micellar liquid chromatography”. Journal of Liquid Chromatography and Related Technologies 32, 1127–1140 (2009).
M. Rambla-Alegre, S. Carda-Broch, J. Esteve-Romero, “Development of a direct and validated method of amoxicillin in physiological fluids using Micelar Liquid Chromatography”. Journal of Separation Science 31, 2813–2819 (2008).
M.A. Raviolo, M. Rambla-Alegre, J. Clausell-Tormos, M.E. Capella-Peiró, S. Carda-Broch, J. Esteve-Romero, “Determination of sulfonamides in milk after precolumn derivatisation by micellar liquid chromatography”. Analytica Chimica Acta 593, 152–156 (2007).
M. Rambla-Alegre, M.T. Gil-Agustí, M.E. Capella-Peiró, S. Carda-Broch, J.S. Esteve-Romero, “Micellar liquid chromatographic determination of five antianginals in pharmaceuticals”. Journal of Chromatography B 839, 89–94 (2006).
Sandra Pous-Torres
(from University of Valencia, Spain)
““Fundamental studies on the resolution capability of reversed-phase liquid chromatography”
Supervisors: María Celia García-Álvarez-Coque, José Ramón Torres-Lapasió and Juan José Baeza-Baeza
University of Valencia (Spain), September 2009
PhD grant, Ministerio de Educación y Ciencia of Spain (September 2005–August 2009).
Three years as Chemistry teacher at Secondary school.
Post-doctorate stay with Prof. García-Álvarez-Coque at the Department of Analytical Chemistry, University of Valencia (Spain) (June 2012–August 2012, and March 2014–May 2014), and with Prof. Peter Schoenmarkers at Van’t Hoff Institute for Molecular Sciences, University of Amsterdam (The Netherlands) (September 2012–February 2012), granted with a val+i+d grant, Generalitat Valenciana (June 2012–February 2014).
Associate Scientist in Analytical Method Development in Octoplus, subsidiary of Dr. Reddy's Laboratories Ltd. (Leiden, The Netherlands) (March 2014–August 2015).
Research Analyst at Analytical Bioscience Division, Biomedical Metabolomics Facility, Analytical Bioscience Division, Leiden University, The Netherlands (September 2015–)
S. Pous-Torres, J.R. Torres-Lapasió, M.J. Ruiz-Ángel, M.C. García-Álvarez-Coque, “Correction of the deviations in the retention times with Chromolith columns associated to the flow rate: Implications in the modelling of the retention behaviour”. Journal of Separation Science 34, 931–938 (2011).
S. Pous-Torres, J.R. Torres-Lapasió, M.J. Ruiz-Ángel, M.C. García-Álvarez-Coque, “Origin and correction of the deviations in retention times at increasing flow rate with Chromolith columns”. Journal of Chromatography A 1217, 5440–5443 (2010).
J.M. Pallicer, S. Pous-Torres, J. Sales, M. Rosés, C. Ràfols, E. Bosch, “Determination of the hydrophobicity of organic compounds measured as log Po/w through a new chromatographic method”. Journal of Chromatography A 1217, 3026–3037 (2010).
J.J. Baeza-Baeza, S. Pous-Torres, J.R. Torres-Lapasió, M.C. García-Álvarez-Coque, “Approaches to characterise chromatographic column performance based on global parameters accounting for peak broadening and skewness”. Journal of Chromatography A 1217, 2147–2157 (2010).
S. Pous-Torres, J.R. Torres-Lapasió, J.J. Baeza-Baeza, M.C. García-Álvarez-Coque, “Combined effect of solvent content, temperature and pH on the chromatographic behaviour of ionisable compounds. III: Considerations about robustness”. Journal of Chromatography A 1216, 8891–8903 (2009).
S. Pous-Torres, J.R. Torres-Lapasió, J.J. Baeza-Baeza, M.C. García-Álvarez-Coque, “Alternating iterative regression method for dead time estimation from experimental designs”. Analytical and Bioanalytical Chemistry 394, 625–636 (2009).
S. Pous-Torres, M.J. Ruiz-Ángel, J.R. Torres-Lapasió, M.C. García-Álvarez-Coque, “Performance of a Chromolith RP-18e column for the screening of β‑blockers”. Journal of Separation Science 32, 2841–2853 (2009).
S. Pous-Torres, J.R. Torres-Lapasió, M.J. Ruiz-Ángel, M.C. García-Álvarez-Coque, “Interpretive optimisation of organic solvent content and flow-rate in the separation of β‑blockers with a Chromolith RP‑18e column”. Journal of Separation Science 32, 2793–2803 (2009).
S. Pous-Torres, J.R. Torres-Lapasió, M.C. García-Álvarez-Coque, “Performance of markers and the homologous series method for dead time estimation in reversed-phase liquid chromatography”. Journal of Liquid Chromatography and Related Technologies 32, 1065–1083 (2009).
S. Pous-Torres, J.J. Baeza-Baeza, J.R. Torres-Lapasió, M.C. García-Álvarez-Coque, “Peak capacity estimation in isocratic elution”. Journal of Chromatography A 1205, 78–89 (2008).
S. Pous-Torres, J.R. Torres-Lapasió, J.J. Baeza-Baeza, M.C. García-Álvarez-Coque, “Combined effect of solvent content, temperature and pH on the chromatographic behaviour of ionisable compounds. II: Benefits of the simultaneous optimisation”. Journal of Chromatography A 1193, 117–128 (2008).
S. Pous-Torres, J.R. Torres-Lapasió, J.J. Baeza-Baeza, M.C. García-Álvarez-Coque, “Combined effect of solvent content, temperature and pH on the chromatographic behaviour of ionisable compounds”. Journal of Chromatography A 1163, 49–62 (2007).
Victoria Concha-Herrera
(from University of Zacatecas, Mexico)
“Optimisation of chromatographic methods for the determination of amino acids and thiols”
Supervisors: María Celia García-Álvarez-Coque and José Ramón Torres-Lapasió
University of Valencia (Spain), July 2005
PhD grant, University of Zacatecas (Mexico) (February 2001–July 2005).
Professor of Department of Chemistry at the University of Zacatecas (Mexico).
V. Concha-Herrera, J.R. Torres-Lapasió, G. Vivó-Truyols, M.C. García-Álvarez-Coque, “A comparative study of the performance of acetonitrile and methanol in the multi-linear gradient separation of proteic primary amino acids”. Analytica Chimica Acta 582, 250–258 (2007).
V. Concha-Herrera, J.R. Torres-Lapasió, G. Vivó-Truyols, M.C. García-Álvarez-Coque, “Separation of proteic primary amino acids under several reversed-phase liquid chromatographic conditions”. Journal of Liquid Chromatography and Related Technologies 29, 2521–2536 (2006).
G. Vivó-Truyols, V. Concha-Herrera, J.R. Torres-Lapasió, M.C. García-Álvarez-Coque, “Robust interpretive optimisation in high-performance liquid chromatography considering uncertainties in peak position”. Journal of Chromatography A 1096, 123–132 (2005).
V. Concha-Herrera, G. Vivó-Truyols, J.R. Torres-Lapasió, M.C. García-Álvarez-Coque, “Limits of multi-linear gradient optimisation in reversed-phase liquid chromatography”. Journal of Chromatography A 1063, 79–88 (2005).
V. Concha-Herrera, G. Vivó-Truyols, J.R. Torres-Lapasió, M.C. García-Álvarez-Coque, “Enhancement of retention predictions in reversed-phase liquid chromatography using reference compounds”. Analytica Chimica Acta 518, 191–197 (2004).
V. Concha-Herrera, J.R. Torres-Lapasió, M.C. García-Álvarez-Coque, “Chromatographic determination of thiols after pre-column derivatization with o-phthalaldehyde and isoleucine”. Journal of Liquid Chromatography and Related Technologies 27, 1593–1609 (2004).
Gabriel Vivó-Truyols
(from University of Palma de Mallorca, Spain)
“Modelling and optimisation in micellar liquid chromatography”
Supervisors: María Celia García-Álvarez-Coque and José Ramón Torres-Lapasió
University of Valencia (Spain), April 2004
PhD. award and Massart award to the best PhD. thesis on Chemometrics (Belgian Society of Chemistry).
Associate Professor at Department of Chemistry, University of Navarra, Pamplona (Spain).
PhD grant, Generalitat Valenciana (July 2002–April 2004).
Post-doctorate stay with Prof. Peter Schoenmarkers at Van’t Hoff Institute for Molecular Sciences, University of Amsterdam (The Netherlands) (July 2004–September 2006), granted initially by the Ministerio de Innovación y Ciencia of Spain; later with the Marie Curie Fellowship (ERC Council).
Ramón y Cajal research position at the Department of Chemistry, University of Balearic Island, Palma de Mallorca (Spain).
Associate Professor at Van’t Hoff Institute for Molecular Sciences, University of Amsterdam (The Netherlands).
G. Vivó-Truyols, J.R. Torres-Lapasió, A.M. van Nederkassel, Y. vander Heyden, D.L. Massart, “Automatic program for peak detection and deconvolution of multi–overlapped chromatographic signals. Part II: Peak model and deconvolution algorithms”. Journal of Chromatography A 1096, 146–155 (2005).
G. Vivó-Truyols, J.R. Torres-Lapasió, A.M. van Nederkassel, Y. vander Heyden, D.L. Massart, “Automatic program for peak detection and deconvolution of multi-overlapped chromatographic signals. Part I: Peak detection”. Journal of Chromatography A 1096, 133–145 (2005).
G. Vivó-Truyols, V. Concha-Herrera, J.R. Torres-Lapasió, M.C. García-Álvarez-Coque, “Robust interpretive optimisation in high-performance liquid chromatography considering uncertainties in peak position”. Journal of Chromatography A 1096, 123–132 (2005).
V. Concha-Herrera, G. Vivó-Truyols, J.R. Torres-Lapasió, M.C. García-Álvarez-Coque, “Limits of multi-linear gradient optimisation in reversed-phase liquid chromatography”. Journal of Chromatography A 1063, 79–88 (2005).
G. Vivó-Truyols, J.R. Torres-Lapasió, M.C. García-Álvarez-Coque, “Estimation of significant solvent concentration ranges and its application to the enhancement of the accuracy of gradient predictions”. Journal of Chromatography A 1057, 31–39 (2004).
V. Concha-Herrera, G. Vivó-Truyols, J.R. Torres-Lapasió, M.C. García-Álvarez-Coque, “Enhancement of retention predictions in reversed-phase liquid chromatography using reference compounds”. Analytica Chimica Acta 518, 191–197 (2004).
G. Vivó-Truyols, J.R. Torres-Lapasió, M.C. García-Álvarez-Coque, “Enhanced calculation of optimal gradient programs in reversed-phase liquid chromatography”. Journal of Chromatography A 1018, 183–196 (2003).
G. Vivó-Truyols, J.R. Torres-Lapasió, M.C. García-Álvarez-Coque, “Error analysis and performance of different retention models in the transference of data from/to isocratic/gradient elution”. Journal of Chromatography A 1018, 169–181 (2003).
G. Vivó-Truyols, J.R. Torres-Lapasió, M.C. García-Álvarez-Coque, “Net analyte signal as a deconvolution-oriented resolution criterion in the optimisation of chromatographic techniques”. Journal of Chromatography A 991, 47–59 (2003).
G. Vivó-Truyols, J.R. Torres-Lapasió, R.D. Caballero, M.C. García-Álvarez-Coque, “Peak deconvolution in one-dimensional chromatography using a two-way data approach”. Journal of Chromatography A 958, 35–49 (2002).
G. Vivó-Truyols, J.R. Torres-Lapasió, M.C. García-Álvarez-Coque, “Towards the optimization of complementary systems in reversed-phase liquid chromatography”. Chromatographia 56, 699–707 (2002).
S.J. López-Grío, G. Vivó-Truyols, J.R. Torres-Lapasió, M.C. García-Álvarez-Coque, “Resolution assessment and performance of several organic modifiers in hybrid micellar liquid chromatography”. Analytica Chimica Acta 433, 187–198 (2001).
G. Vivó-Truyols, J.R. Torres-Lapasió, A. Garrido-Frenich, M.C. García-Álvarez-Coque, “A hybrid genetic algorithm with local search. II. Continuous variables: Multibatch peak deconvolution”. Chemometrics and Intelligent Laboratory Systems 59, 107–120 (2001).
G. Vivó-Truyols, J.R. Torres-Lapasió, M.C. García-Álvarez-Coque, “A hybrid genetic algorithm with local search. I. Discrete variables: Optimisation of complementary mobile phases”. Chemometrics and Intelligent Laboratory Systems 59, 89–106 (2001).
G. Vivó-Truyols, J.R. Torres-Lapasió, M.C. García-Álvarez-Coque, “Complementary mobile-phase optimisation for resolution enhancement in high-performance liquid chromatography”. Journal of Chromatography A 876, 17–35 (2000).
María Elisa Capella-Peiró
(from University Jaume I, Castellón, Spain)
"Determination of compounds with diverse hydrophobicities by micellar liquid chromatography”
Supervisors: Josep Esteve-Romero and Samuel Carda-Broch
University Jaume I, Castellón (Spain), June 2003
Chemistry teacher at Secondary school
A. Martinavarro-Domínguez, D. Bose, A. Durgbanshi, M. Gil-Agustí, M.E. Capella-Peiró, S. Carda-Broch, J. Esteve-Romero, “Monitoring bronchodilators with direct injection”. Journal of Chromatography A 1073, 309–315 (2005).
M.E. Capella-Peiró, D. Bose, M. Gil-Agustí, J. Esteve-Romero, S. Carda-Broch, “Direct injection determination of benzoylecgonine, heroin, 6-monoacetyl-morphine and morphine in serum by micellar liquid chromatography”. Journal of Chromatography A 1073, 277–283 (2005).
M.E. Capella-Peiró, D. Bose, A. Durgbanshi, A. Martinavarro-Domínguez, M. Gil-Agustí, J. Esteve-Romero, S. Carda-Broch, “Simultaneous determination of three opiates in serum by micellar liquid chromatography using direct injection”. Journal of AOAC International 88, 428–435 (2005).
M.E. Capella-Peiró, S. Carda-Broch, Ll. Monferrer-Pons, J. Esteve-Romero, “Micellar liquid chromatography determination of nicotinic acid and nicotinamide after precolumn König reaction derivatization”. Analytica Chimica Acta 517, 81–87 (2004).
D. Bose, A. Durgbanshi, M.E. Capella-Peiró, M. Gil-Agustí, J. Esteve-Romero, S. Carda-Broch, “Micellar liquid chromatography determination of some biogenic amines with electrochemical detection”. Journal of Pharmaceutical and Biomedical Analysis 36, 357–363 (2004).
M.E. Capella-Peiró, D. Bose, A. Durgbanshi, M. Gil-Agustí, S. Carda-Broch, J. Esteve-Romero, “Determination of carbamate pesticides using micellar liquid chromatography”. Indian Journal of Chemistry, Section A: Inorganic, Bio-inorganic, Physical, Theoretical & Analytical Chemistry 42A, 1417–1422 (2004).
D. Bose, A. Durgbanshi, M.E. Capella-Peiró, M. Gil-Agustí, S. Carda-Broch, J. Esteve-Romero, “Determination of drugs in pharmaceuticals and pesticides by micellar liquid chromatography”. Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry 43B, 1973–1982 (2004).
E. Capella-Peiró, Ll. Monferrer-Pons, M.C. García-Álvarez-Coque, J. Esteve-Romero, “Flow-injection spectrophotometric determination of nicotinic acid in micellar medium of N‑cetylpyridinium chloride”. Analytica Chimica Acta 427, 93–100 (2001).
M. Gil-Agustí, M.E. Capella-Peiró, L. Monferrer-Pons, M.C. García-Álvarez-Coque, J. Esteve-Romero, “Chromatographic analysis of phenethylamine-antihistamine combinations using C8, C18 or cyano columns and micellar sodium dodecyl sulfate-pentanol mixtures”. Analyst 126, 457–464 (2001).
María José Ruiz-Ángel
(from University of Valencia, Spain)
“Micellar liquid chromatography: A competitive technique against classical reversed-phase liquid chromatography”
Supervisors: María Celia García-Álvarez-Coque and Ernesto Francisco Simó-Alfonso
University of Valencia (Spain), July 2003
PhD grant, Ministerio de Educación y Ciencia of Spain (January 1989–December 2003)
PhD. award
Post-doctorate stay with Dr. Alain Berthod at the Laboratoire des Sciences Analytiques. Université Claude Bernard, Lyon I, Villeurbanne Cedex (France), granted by Generalitat Valenciana.
Ramón y Cajal position at Department of Analytical Chemistry, University of Valencia (Spain).
Professor at the Department of Analytical Chemistry, University of Valencia (Spain).
M.J. Ruiz-Ángel, S. Carda-Broch, M.C. García-Álvarez-Coque, A. Berthod, “Micellar versus hydro-organic mobile phases for retention-hydrophobicity relationship studies with ionizable diuretics and an anionic surfactant”. Journal of Chromatography A 1030, 279–288 (2004).
R. Ruiz, M.J. Ruiz-Ángel, M.C. García-Álvarez-Coque, C. Ràfols, M. Rosés, E. Bosch, “Hydrophobic and cation exchange mechanisms in the retention of basic compounds in a polymeric column”. Journal of Chromatography A 1028, 139–148 (2004).
M.J. Ruiz-Ángel, J.R. Torres-Lapasió, M.C. García-Álvarez-Coque, “Effect of pH and the presence of micelles on the resolution of diuretics by reversed-phase liquid chromatography”. Journal of Chromatography A 1022, 51–65 (2004).
M.J. Ruiz-Ángel, S. Carda-Broch, E.F. Simó-Alfonso, M.C. García-Álvarez-Coque, “Optimised procedures for the reversed-phase liquid chromatographic analysis of formulations containing tricyclic antidepressants”. Journal of Pharmaceutical and Biomedical Analysis 32, 71–84 (2003).
M.J. Ruiz-Ángel, J.R. Torres-Lapasió, S. Carda-Broch, M.C. García-Álvarez-Coque, “Improvement of peak shape and separation performance of b-blockers in conventional reversed-phase columns using solvent modifiers”. Journal of Chromatographic Science 41, 350–358 (2003).
M.J. Ruiz-Ángel, R.D. Caballero, E. Simó-Alfonso, M.C. García-Álvarez-Coque, “Micellar liquid chromatography: Suitable technique for screening analysis”. Journal of Chromatography A 947, 31–45 (2002).
M.J. Ruiz-Ángel, S. Carda-Broch, J.R. Torres-Lapasió, E.F. Simó-Alfonso, M.C. García-Álvarez-Coque, “Micellar-organic versus aqueous-organic mobile phases for the screening of β-blockers”. Analytica Chimica Acta 454, 109–123 (2002).
S. Carda-Broch, J. Esteve-Romero, M.J. Ruiz-Ángel, M.C. García-Álvarez-Coque, “Determination of furosemide in urine samples by direct injection in a micellar liquid chromatographic system”. Analyst 127, 29–34 (2002).
M.J. Ruiz-Ángel, P. Fernández-López, J.A. Murillo-Pulgarín, M.C. García-Álvarez-Coque, “Control of propranolol intake by direct chromatographic detection of α-naphthoxylactic acid in urine”. Journal of Chromatography B 767, 277–283 (2002).
Mayte Gil-Agustí
(from University Jaume I, Castellón, Spain)
“Micellar liquid chromatographt for the control of pharmaceutical products”
Supervisors: María Celia García-Álvarez-Coque and Josep Esteve-Romero
University Jaume I, Castellón (Spain), March, 2001
PhD. award
Post-doctorate stays with Pier Giorgio Righetti at the Department of Agricultural and Industrial Biotechnology, University of Verona (Italy), and with Michael H. Abraham at the Department of Chemistry, University College London (United Kingdom)-
Associate researcher at the Department of Physical and Analytical Chemistry, University Jaume I, Castellón (Spain)-
Project coordinator at Energy Technological Institute, Paterna, Valencia (Spain).
M. Gil-Agustí, M.E. Capella-Peiró, L. Monferrer-Pons, M.C. García-Álvarez-Coque, J. Esteve-Romero, “Chromatographic analysis of phenethylamine-antihistamine combinations using C8, C18 or cyano columns and micellar sodium dodecyl sulfate-pentanol mixtures”. Analyst 126, 457–464 (2001).
M. Gil-Agustí, Ll. Monferrer-Pons, M.C. García-Álvarez-Coque, J. Esteve-Romero, “Determination of active ingredients in cough-cold preparations by micellar liquid chromatography”. Talanta 54, 621–630 (2001).
M. Gil-Agustí, Ll. Monferrer-Pons, J. Esteve-Romero, M.C. García-Álvarez-Coque, “Quantitation of antihistamines in pharmaceutical preparations by liquid chromatography with a micellar mobile phase of sodium dodecyl sulfate and pentanol”. Journal of AOAC International 84, 1687–1694 (2001).
M. Gil-Agustí, J.R. Torres-Lapasió, M.C. García-Álvarez-Coque, J. Esteve-Romero, “Comparison of the performance of butanol and pentanol as modifiers in the micellar liquid chromatographic determination of some phenethylamines”. Journal of Chromatography A 866, 35–49 (2000).
M. Gil-Agustí, M.C. García-Álvarez-Coque, J. Esteve-Romero, “Correlation between hydrophobicity and retention data of several antihistamines in reversed-phase liquid chromatography with aqueous-organic and micellar-organic mobile phases”. Analytica Chimica Acta 421, 45–55 (2000).
M. Gil-Agustí, S. Carda-Broch, M.C. García-Álvarez-Coque, J. Esteve-Romero, “Use of micellar mobile phases for the chromatographic determination of clorazepate, diazepam, and diltiazem in pharmaceuticals”. Journal of Chromatographic Science 38, 521–527 (2000).
M. Gil-Agustí, S. Carda-Broch, M.C. García-Álvarez-Coque, J. Esteve-Romero, “Micellar liquid chromatographic determination of anti-convulsant drugs in pills and capsules”. Journal of Liquid Chromatography and Related Technologies 23, 1387–1401 (2000).
J. Esteve-Romero, M. Gil-Agustí, S. Carda-Broch, J.R. Torres-Lapasió, M.C. García-Álvarez-Coque, “Analysis of pharmaceuticals by micellar liquid chromatography”. Recent Research Developments in Pure and Applied Analytical Chemistry, 3, pp. 157–168 (2001), Transworld Research Network, Trivandrum (India). ISBN: 81-86846-97-2.
Rosendo David Caballero
(from National University of Entre Ríos, Gualeguaychú, Entre Ríos, Argentina)
“Determination of antibacterial reagents in foods by micellar liquid chromatography”
Supervisors: María Celia García-Álvarez-Coque and Juan José Baeza-Baeza
University of Valencia (Spain), October 2001
PhD grant, Instituto de Cooperación Iberoamericana of Spain (October 1997–June 2001).
Laboratory director in a detergent industry (Industrias jaboneras LINASA, in Murcia, Spain)
G. Vivó-Truyols, J.R. Torres-Lapasió, R.D. Caballero, M.C. García-Álvarez-Coque, “Peak deconvolution in one-dimensional chromatography using a two-way data approach”. Journal of Chromatography A 958, 35–49 (2002).
R.D. Caballero, M.C. García-Álvarez-Coque, J.J. Baeza-Baeza, “Parabolic-Lorentzian modified Gaussian model for describing and deconvolving chromatographic peaks”. Journal of Chromatography A 954, 59–76 (2002).
M.J. Ruiz-Ángel, R.D. Caballero, E. Simó-Alfonso, M.C. García-Álvarez-Coque, “Micellar liquid chromatography: Suitable technique for screening analysis”. Journal of Chromatography A 947, 31–45 (2002).
R.D. Caballero, J.R. Torres-Lapasió, M.C. García-Álvarez-Coque, G. Ramis-Ramos, “Rapid liquid chromatographic determination of tetracyclines in animal feeds using a surfactant solution as mobile phase”. Analytical Letters 35, 687–705 (2002).
R.D. Caballero, S. Carda-Broch, M.C. García-Álvarez-Coque, “Hydro-organic and micellar-organic reversed-phase liquid cromatographic procedures for the evaluation of sulphonamides in pharmaceuticals”. Analytical Letters 34, 1189–1203 (2001).
R.D. Caballero, S.J. López-Grío, J.R. Torres-Lapasió, M.C. García-Álvarez-Coque, “Single-peak resolution criteria for optimization of mobile phase composition in liquid chromatography”. Journal of Liquid Chromatography and Related Technologies 24, 1895–1919 (2001).
R.D. Caballero, J.R. Torres-Lapasió, J.J. Baeza-Baeza, M.C. García-Álvarez-Coque, “Micellar chromatographic procedure with direct injection for the determination of sulfonamides in milk and honey samples”. Journal of Liquid Chromatography and Related Technologies 24, 117–131 (2001).
Luis Álvarez-Rodríguez
(from University of Badajoz, Spain)
“Spectrophotometric determination of phenols, carbamates, pyridines and nitrobenzens by derivatization in micellar media"
Supervisors:María Celia García-Álvarez-Coque and Josep Esteve-Romero
University Jaume I, Castellón (Spain), April 1999
PhD. award
Chemistry teacher at Secondary school
Associate Professor at the Department of Physical and Analytical Chemistry, University Jaume I, Castellón (Spain)
Ll. Monferrer-Pons, L. Álvarez-Rodríguez, J.S. Esteve-Romero, M.C. García-Álvarez-Coque, “Flow-injection analysis of pyridoxine hydrochloride by coupling with the diazonium ion of p‑sulfanilic acid”. Analytical Letters 33, 539–552 (2000).
L. Álvarez-Rodríguez, J. Esteve-Romero, I. Escrig-Tena, M.C. García-Álvarez-Coque, “Flow-injection spectrophotometric determination of phenolic drugs and carbamate pesticides by coupling with diazotized 2,4,6,-trimethylaniline”. Journal of AOAC International 82, 937–947 (1999).
Ll. Monferrer-Pons, L. Álvarez-Rodríguez, J.S. Esteve-Romero, M.C. García-Álvarez-Coque, “Spectrophotometric determination of B6 vitamins by coupling with diazotized p-sulfanilic acid in micellar medium of N-cetylpyridinium chloride”. Analytical Letters 32, 51–63 (1999).
I. Escrig-Tena, L. Álvarez-Rodríguez, J.S. Esteve-Romero, M.C. García-Álvarez-Coque, “Micellar modified spectrophotometric determination of nitrobenzenes based upon reduction with tin(II), diazotisation and coupling with the Bratton-Marshall reagent”. Talanta 47, 43–52 (1998).
L. Álvarez-Rodríguez, Ll. Monferrer-Pons, J.S. Esteve-Romero, M.C. García-Álvarez-Coque, G. Ramis‑Ramos, “Spectrophotometric determination of carbamate pesticides with diazotized trimethylaniline in a micellar medium of sodium dodecyl sulfate”. Analyst 122, 459–463 (1997).
J.S. Esteve-Romero, L. Álvarez-Rodríguez, M.C. García-Álvarez-Coque, G. Ramis-Ramos, “Spectrophotometric determination of phenols by coupling with diazotized 2,4,6−trimethylaniline in a micellar medium”. Analyst 119, 1381–1386 (1994).
Sagrario Torres-Cartas
(from University of Valencia, Spain)
“Chromatographic determination of steroids with micellar mobile phases”
Supervisors: María Celia García-Álvarez-Coque and Rosa María Villanueva-Camañas
University of Valencia (Spain), June1999
PhD grant, Ministerio de Educación y Ciencia of Spain (January 1994–December 1997)
Professor at the Department of Chemistry of the Polytechnic University of Valencia (Spain)
S. Torres-Cartas, R.M. Villanueva-Camañas, M.C. García-Álvarez-Coque, “Determination of steroidal hormones in urine samples by micellar liquid chromatography following solid-phase extraction”. Journal of Liquid Chromatography and Related Technologies 24,1089–1103 (2001).
S. Torres-Cartas, R.M. Villanueva-Camañas, M.C. García-Álvarez-Coque, “Retention-structure relationship studies for some steroidal hormones in micellar liquid chromatography”. Chromatographia 51, 577–585 (2000).
S. Torres-Cartas, J.R. Torres-Lapasió, R.M. Villanueva-Camañas, M.C. García-Álvarez-Coque, “Resolution of mixtures of steroidal hormones with micellar eluents of sodium dodecyl sulphate and acetonitrile or pentanol”. Chromatographia 52, 185–189 (2000).
S. Torres-Cartas, R.M. Villanueva-Camañas, M.C. García-Álvarez-Coque, “Sensitized lanthanide fluorescence detection of steroidal hormones”. Journal of Liquid Chromatography and Related Technologies 23, 1171–1186 (2000).
S. Torres-Cartas, R.M. Villanueva-Camañas, M.C. García-Álvarez-Coque, “Modelling and optimization of the separation of steroids eluted with a micellar mobile phase of sodium dodecyl sulphate containing acetonitrile”. Analytica Chimica Acta 333, 31–40 (1996).
S. Torres-Cartas, M.C. García-Álvarez-Coque, R.M. Villanueva-Camañas, “Determination of anabolic steroids in pharmaceuticals by liquid chromatography with a microemulsion of sodium dodecyl sulfate and pentanol as mobile phase”. Analytica Chimica Acta 302, 163–172 (1995).
Sergio López-Grío
(from University of Leon, Nicaragua)
“Modelling and resolution in micellar liquid chromatoghraphy with hybrid mobile phases”
Supervisors: María Celia García-Álvarez-Coque and Juan José Baeza-Baeza
University of Valencia (Spain), September 1999
PhD grant, Instituto de Cooperación Iberoamericana (November 1995–October 1998) and Generalitat Valenciana (January 1996–December 1999)
Professor at the Department of Chemistry of the University of Leon (Nicaragua)
S.J. López-Grío, G. Vivó-Truyols, J.R. Torres-Lapasió, M.C. García-Álvarez-Coque, “Resolution assessment and performance of several organic modifiers in hybrid micellar liquid chromatography”. Analytica Chimica Acta 433, 187–198 (2001).
S. López-Grío, J.J. Baeza-Baeza, M.C. García-Álvarez-Coque, “Evaluation of the elution strength of the surfactant and organic solvent in hybrid micellar mobile phases”. Journal of Liquid Chromatography and Related Technologies 24, 2765–2783 (2001).
S. López-Grío, M.C. García-Álvarez-Coque, W.L. Hinze, F.H. Quina, A. Berthod, “Effect of a variety of organic additives on retention and efficiency in micellar liquid chromatography”. Analytical Chemistry 72, 4826–4835 (2000).
S. López-Grío, J.R. Torres-Lapasió, J.J. Baeza-Baeza, M.C. García-Álvarez-Coque, “Micellar liquid chromatography separation of amino acids using pre- and post-column o‑phthalaldehyde/N-acetylcysteine derivatization”. Analytica Chimica Acta 418, 153–165 (2000).
S. López-Grío, J.J. Baeza-Baeza, M.C. García-Álvarez-Coque, “Modelling of the elution behaviour in hybrid micellar eluents with different organic modifiers”. Analytica Chimica Acta 381, 275–285 (1999).
S. López-Grío, J.J. Baeza-Baeza, M.C. García-Álvarez-Coque, “Influence of the addition of modifiers on solute-micelle interaction in hybrid micellar liquid chromatography”. Chromatographia 48, 655–663 (1998).
Samuel Carda-Broch
(from University Jaume I, Castellón, Spain)
“Analysis of samples containing diuretics by direct injection in a micellar chromatographic system”
Supervisors: María Celia García-Álvarez-Coque and Josep Esteve-Romero
University of Valencia (Spain), December 1999
PhD grant, Generalitat Valenciana (January 1996–December 1999)
PhD. award
Analyst in the research and development laboratory of the pharmaceutical industry Italfármaco (Madrid, Spain)
Post-doctorate stays with Dr. Alain Berthod at the Laboratoire des Sciences Analytiques. Université Claude Bernard, Lyon I, Villeurbanne Cedex (France), and Daniel W. Armstrong at the Department of Chemistry, Iowa State University, Ames, IA (USA).
Marie Curie Fellowship (ERC Council)
Professor at the Department of Physical and Analytical Chemistry, University Jaume I, Castellón (Spain).
A. Detroyer, Y. vander Heyden, S. Carda-Broch, M.C. García-Álvarez-Coque, D.L. Massart, “Quantitative structure-retention and retention-activity relationships of β-blocking agents by micellar liquid chromatography”. Journal of Chromatography A 912, 211–221 (2001).
R.D. Caballero, S. Carda-Broch, M.C. García-Álvarez-Coque, “Hydro-organic and micellar-organic reversed-phase liquid cromatographic procedures for the evaluation of sulphonamides in pharmaceuticals”. Analytical Letters 34, 1189–1203 (2001).
J. Esteve-Romero, M. Gil-Agustí, S. Carda-Broch, J.R. Torres-Lapasió, M.C. García-Álvarez-Coque, “Analysis of pharmaceuticals by micellar liquid chromatography”. Recent Research Developments in Pure and Applied Analytical Chemistry, 3, pp. 157–168 (2001), Transworld Research Network, Trivandrum (India). ISBN: 81-86846-97-2.
S. Carda-Broch, J.R. Torres-Lapasió, J.S. Esteve-Romero, M.C. García-Álvarez-Coque, “Use of a three-factor interpretive optimisation strategy in the development of an isocratic chromatographic procedure for the screening of diuretics in urine samples using micellar mobile phases”. Journal of Chromatography A 893, 321–337 (2000).
S. Carda-Broch, J. Esteve-Romero, M.C. García-Álvarez-Coque, “Furosemide assay in pharmaceuticals by micellar liquid chromatography: Study of the stability of the drug”. Journal of Pharmaceutical and Biomedical Analysis 23, 803–817 (2000).
M. Gil-Agustí, S. Carda-Broch, M.C. García-Álvarez-Coque, J. Esteve-Romero, “Use of micellar mobile phases for the chromatographic determination of clorazepate, diazepam, and diltiazem in pharmaceuticals”. Journal of Chromatographic Science 38, 521–527 (2000).
M. Gil-Agustí, S. Carda-Broch, M.C. García-Álvarez-Coque, J. Esteve-Romero, “Micellar liquid chromatographic determination of anti-convulsant drugs in pills and capsules”. Journal of Liquid Chromatography and Related Technologies 23, 1387–1401 (2000).
A. Berthod, S. Carda-Broch, M.C. García-Álvarez-Coque, “Hydrophobicity of ionizable compounds. A theoretical study and measurements of diuretic octanol-water partition coefficients by countercurrent chromatography”. Analytical Chemistry 71, 879–888 (1999).
S. Carda-Broch, J.R. Torres-Lapasió, M.C. García-Álvarez-Coque, “Evaluation of several global resolution functions for liquid chromatography”. Analytica Chimica Acta 396, 61–74 (1999).
M.C. García-Álvarez-Coque, S. Carda-Broch, “Direct injection of physiological fluids in micellar liquid chromatography” (review). Journal of Chromatography B 736, 1–18 (1999).
I.M. Lomniczi-de-Upton, J.R. de la Fuente, J.S. Esteve-Romero, M.C. García-Álvarez-Coque, S. Carda-Broch, “Chromatographic detection of sesquiterpene lactones in Parthenium plants from northwest Argentina”. Journal of Liquid Chromatography and Related Technologies 22, 909–921 (1999).
S. Carda-Broch, I. Rapado-Martínez, J. Esteve-Romero, M.C. García-Álvarez-Coque, “Analysis of urine samples containing cardiovascular drugs by micellar liquid chromatography with fluorimetric detection”. Journal of Chromatographic Science 37, 93–102 (1999).
S. Carda-Broch, J.S. Esteve-Romero, M.C. García-Álvarez-Coque, “Chromatographic determination of diuretics in urine samples using hybrid micellar mobile phases with fluorimetric detection”. Analytica Chimica Acta 375, 143–154 (1998).
S. Carda-Broch, J.S. Esteve-Romero, M.C. García-Álvarez-Coque, “Liquid chromatographic determination of some thiazide diuretics in pharmaceuticals with a sodium dodecyl sulfate mobile phase”. Analyst 123, 301–306 (1998).
S. Carda-Broch, M.C. García-Álvarez-Coque, E.F. Simó-Alfonso, J.S. Esteve-Romero, “Micellar liquid chromatographic determination of diuretics by diazotization and coupling with the Bratton-Marshall reagent”. Analytica Chimica Acta 353, 215–226 (1997).
Inmaculada Rapado-Martínez
(from University of Valencia, Spain)
“Use of organised media for the determination of β-blockers”
Supervisors: María Celia García-Álvarez-Coque and Rosa María Villanueva-Camañas
University of Valencia (Spain), May 1997
Specialist in Clinical Analysis, Hospital 12 de Octubre, Madrid, Spain
I. Rapado-Martínez, R.M. Villanueva-Camañas, M.C. García-Álvarez-Coque, “Micellar liquid chromatography: A worthy technique for the determination of β-antagonists in urine samples”. Analytical Chemistry 71, 319–326 (1999).
S. Carda-Broch, I. Rapado-Martínez, J. Esteve-Romero, M.C. García-Álvarez-Coque, “Analysis of urine samples containing cardiovascular drugs by micellar liquid chromatography with fluorimetric detection”. Journal of Chromatographic Science 37, 93–102 (1999).
I. Rapado-Martínez, M.C. García-Álvarez-Coque, R.M. Villanueva-Camañas, “Liquid chromatographic procedure for the evaluation of β-blockers in pharmaceuticals using hybrid micellar mobile phases”. Journal of Chromatography A 765, 221–231 (1997).
I. Rapado-Martínez, M.C. García-Álvarez-Coque, R.M. Villanueva-Camañas, “Performance of micellar mobile phases in reversed-phase chromatography for the analysis of pharmaceuticals containing β-blockers and other antihypertensive drugs”. Analyst 121, 1677–1682 (1996).
I. Rapado-Martínez, R.M. Villanueva-Camañas, M.C. García-Álvarez-Coque, “Micelle-stabilized room-temperature phosphorimetric procedure for the determination of naproxen and propranolol in pharmaceutical preparations”. Analyst 119, 1093–1097 (1994).
José Ramón Torres-Lapasió
(from University of Valencia, Spain)
“Modelling and optimisation in micellar liquid chromatography”
Supervisors: María Celia García-Álvarez-Coque and Juan José Baeza-Baeza
University of Valencia (Spain), February 1996
PhD. award
Post-doctorate position with Prof. Guillermo Ramis, Department of Analytical Chemistry, University of Valencia (Spain)
Post-doctorate stay with Prof. Víctor Cerdà, Department of Chemistry, University of Balearic Islands, Palma de Mallorca (Spain), and Prof. Desirée Luc Massart at FABI, Pharmaceutical Institute, Faculty of Medicine and Pharmacy, Vrije Universiteit, Brussel (Belgium).
Associate Professor at Department of Chemistry, University of Navarra, Pamplona (Spain).
Ramón y Cajal position at Department of Analytical Chemistry, University of Valencia (Spain).
Professor at the Department of Analytical Chemistry, University of Valencia (Spain).
J.R. Torres-Lapasió, J.J. Baeza-Baeza, M.C. García-Álvarez-Coque, “A model for the description, simulation and deconvolution of skewed chromatographic peaks”. Analytical Chemistry 69, 3822–3831 (1997).
M.C. García-Álvarez-Coque, J.R. Torres-Lapasió, J.J. Baeza-Baeza, “Modelling of retention behaviour of solutes in micellar liquid chromatography” (review). Journal of Chromatography A 780, 129–148 (1997).
J.R. Torres-Lapasió, J.J. Baeza-Baeza, M.C. García-Álvarez-Coque, “Description of the retention behaviour in micellar liquid chromatography as a function of pH, surfactant and modifier concentration”. Journal of Chromatography A 769, 155–168 (1997).
J.R. Torres-Lapasió, M.C. García-Álvarez-Coque, J.J. Baeza-Baeza, “Global treatment of chromatographic data with MICHROM”. Analytica Chimica Acta 348, 187–196 (1997).
M.C. García-Álvarez-Coque, J.R. Torres-Lapasió, J.J. Baeza-Baeza, “Description of the partitioning behaviour of solutes and data treatment in micellar liquid chromatography with modifiers”. Analytica Chimica Acta 324, 163–173 (1996).
J.R. Torres-Lapasió, J.J. Baeza-Baeza, M.C. García-Álvarez-Coque, “On the measurement of dead time in micellar liquid chromatography”. Journal of Liquid Chromatography and Related Technologies 19, 1205–1228 (1996).
R.M. Villanueva-Camañas, J.M. Sanchis-Mallols, J.R. Torres-Lapasió, G. Ramis-Ramos, “Analysis of pharmaceutical preparations containing catecholamines by micellar liquid chromatography with spectrophotometric detection”. Analyst 120, 1767–1772 (1995).
Y.L. Xie, J.J. Baeza-Baeza, J.R. Torres-Lapasió, M.C. García-Álvarez-Coque, G. Ramis-Ramos, “Modelling and prediction of retention in high-performance liquid chromatography by using neural networks”. Chromatographia 41, 435–444 (1995).
J.R. Torres-Lapasió, M.J. Medina-Hernández, R.M. Villanueva-Camañas, M.C. García-Álvarez-Coque, “Description of the retention behaviour of solutes in micellar liquid chromatography with organic modifiers: Comparison of two methods”. Chromatographia 40, 279–286 (1995).
J.R. Torres-Lapasió, R.M. Villanueva-Camañas, J.M. Sanchis-Mallols, M.J. Medina-Hernández, M.C. García-Álvarez-Coque, “Interpretive strategy for optimization of surfactant and alcohol concentration in micellar liquid chromatography”. Journal of Chromatography A 677, 239–253 (1994).
J.M. Sanchis-Mallols, J.R. Torres-Lapasió, R.M. Villanueva-Camañas, G. Ramis-Ramos, “Determination of catecholamines in urine by micellar liquid chromatography with coulometric detection”. Chromatographia 39, 591–596 (1994).
J.R. Torres-Lapasió, R.M. Villanueva-Camañas, J.M. Sanchis-Mallols, M.J. Medina-Hernández, M.C. García-Álvarez-Coque, “Modelling of the retention behaviour of solutes in micellar liquid chromatography with organic modifiers”. Journal of Chromatography 639, 87–96 (1993).
Yolanda Martín-Biosca
(from University of Valencia, Spain)
“Contribution to the knowledge and development of analytical applications of the effects associated to the use of termal lens spectrometry”
Supervisors: María Celia García-Álvarez-Coque and Guillermo Ramis-Ramos
University of Valencia (Spain), July 1996
PhD grant, Generalitat Valenciana (September 1992–August 1996).
Professor at the Department of Analytical Chemistry, University of Valencia (Spain).
Y. Martín-Biosca, C. Rozé, G. Ramis-Ramos, “Modeling of the low-frequency noise in thermal lens spectrometry”. Israel Journal of Chemistry 38, 169–174 (1998).
Y. Martín-Biosca, G. Ramis-Ramos, C. Rozé, L. Le Sceller, “Analytical study of the thermal induced oscillations known as heartbeats”. Microchemical Journal 58, 80–89 (1998).
Y. Martín-Biosca, M.C. García-Álvarez-Coque, G. Ramis-Ramos, “Determination of inorganic species by thermal lens spectrometry” (review). Trends in Analytical Chemistry 16, 342–351 (1997).
Y. Martín-Biosca, J.J. Baeza-Baeza, G. Ramis-Ramos, “Determination of clenbuterol in urine by azo-dye precolumn derivatization and micellar liquid chromatography”. Chromatographia 44, 145–150 (1997).
Y. Martín Biosca, G. Ramis Ramos, “Optical saturation thermal lens spectrometry in non-polar solvents”. Analytica Chimica Acta 345, 257–263 (1997).
Y. Martín Biosca, J.J. Baeza Baeza, G. Ramis Ramos, “Quality control of pharmaceuticals containing clenbuterol by thermal lens spectrometry”. Journal of Pharmaceutical and Biomedical Analysis 14, 1037–1041 (1996).
Y. Martín-Biosca, E.F. Simó-Alfonso, J.S. Esteve-Romero, J.J. Baeza-Baeza, G. Ramis-Ramos, “Optical saturation, diffusion and convection effects in thermal lens spectrometry”. Analytica Chimica Acta 307, 145–154 (1995).
Y. Martín Biosca, M.J. Medina-Hernández, M.C. García-Álvarez-Coque, G. Ramis-Ramos, “Effect of the nature of the solvent on the limit of detection in thermal lens spectrometry”. Analytica Chimica Acta 296, 285–294 (1994).
Y. Martín Biosca, M.C. García-Álvarez-Coque, G. Ramis-Ramos, “Thermal lens spectrometry in biochemical analysis” (review). Journal of Biochemical and Biophysical Methods 29, 1–21 (1994).
E. Simó-Alfonso, Y. Martín-Biosca, M.C. García-Álvarez-Coque, G. Ramis-Ramos, “On the use of mixing reactors in flow injection analysis with thermal lens calorimetric detection”. Thermochimica Acta 219, 53–64 (1993).
Llorenç Monferrer-Pons
(from University Jaume I, Castellón, Spain)
“Spectrophotometric determination of nitrogen heterocycles and carbamates in organised media”
Supervisors: María Celia García-Álvarez-Coque and Josep Esteve-Romero
University Jaume I, Castellón (Spain), September 1996
PhD. award
Chemistry teacher at Secondary school
Associate Professor at the Department of Physical and Analytical Chemistry, University Jaume I, Castellón (Spain).
L. Álvarez-Rodríguez, Ll. Monferrer-Pons, J.S. Esteve-Romero, M.C. García-Álvarez-Coque, G. Ramis‑Ramos, “Spectrophotometric determination of carbamate pesticides with diazotized trimethylaniline in a micellar medium of sodium dodecyl sulfate”. Analyst 122, 459–463 (1997).
L. Álvarez-Rodríguez, Ll. Monferrer-Pons, J.S. Esteve-Romero, M.C. García-Álvarez-Coque, G. Ramis‑Ramos, “Spectrophotometric determination of carbamate pesticides with diazotized trimethylaniline in a micellar medium of sodium dodecyl sulfate”. Analyst 122, 459–463 (1997).
Ll. Monferrer-Pons, M.C. García-Álvarez-Coque, J.S. Esteve-Romero, “Assay of chlorpheniramine maleate in pharmaceutical formulations by enhanced micellar colorimetry”. Química Analítica 16, 133–138 (1997).
Ll. Monferrer-Pons, J.S. Esteve-Romero, G. Ramis-Ramos, M.C. García-Álvarez-Coque, “Spectrophotometric determination of the antihistamines carbinoxamine maleate and doxylamine succinate in an N-cetylpyridinium chloride micellar medium”. Analytical Letters 29, 1399–1413 (1996).
J.S. Esteve-Romero, Ll. Monferrer-Pons, G. Ramis-Ramos, M.C. García-Álvarez-Coque, “Enhanced spectrophotometric determination of nicotinic acid in a sodium dodecyl sulphate micellar medium”. Talanta 42, 737–745 (1995).
J.S. Esteve-Romero, Ll. Monferrer-Pons, M.C. García-Álvarez-Coque, G. Ramis-Ramos, “Determination of pyrrole derivatives and hydroxyproline with 4-(dimethylamino)benzaldehyde in a micellar medium”. Analytical Letters 27, 1557–1567 (1994).
Emilio Bonet-Domingo
(from University of Valencia, Spain)
“Micellar liquid chromatography, a useful technique for the determination of diuretics”
Supervisors: María Celia García-Álvarez-Coque and María José Medina-Hernández
University of Valencia, (Spain) March 1993
Director of the "Water control laboratory" (GAMASER) in Aguas de Valencia, Valencia (Spain)
E. Bonet-Domingo, J.R. Torres-Lapasió, M.J. Medina-Hernández, M.C. García-Álvarez-Coque, “Chromatographic monitoring of diuretics in urine samples using a sodium dodecyl sulphate-propanol micellar eluent”. Analytica Chimica Acta 287, 201–210 (1994).
E. Bonet-Domingo, M.J. Medina-Hernández, M.C. García-Álvarez-Coque, “A micellar liquid chromatographic procedure for the determination of amiloride, bendroflumethiazide, chlorthalidone, spironolactone and triamterene in pharmaceuticals”. Journal of Pharmaceutical and Biomedical Analysis 11, 711–716 (1993).
M.J. Medina-Hernández, E. Bonet-Domingo, G. Ramis-Ramos, M.C. García-Álvarez-Coque, “On the retention of diuretics in micellar liquid chromatography and their site of action within the nephron”. Analytical Letters 26, 1881–1889 (1993).
E. Bonet-Domingo, M.J. Medina-Hernández, M.C. García-Álvarez-Coque, “On the direct injection of urine samples in micellar liquid chromatography”. Química Analítica 12, 167–172 (1993).
E. Bonet-Domingo, M.J. Medina-Hernández, G. Ramis-Ramos, M.C. García-Álvarez-Coque, “Evaluation of diuretics in pharmaceuticals by high-performance liquid chromatography with a 0.05 mol dm–3 sodium dodecyl sulfate–3% propanol mobile phase”. Analyst 117, 843–847 (1992).
E. Bonet-Domingo, M.J. Medina-Hernández, G. Ramis-Ramos, M.C. García-Álvarez-Coque, “High‑performance liquid chromatographic determination of diuretics in urine by micellar liquid chromatography”. Journal of Chromatography, Biomedical Applications 582, 189–194 (1992).
María Ángeles Rius-Revert
(from University of Valencia, Spain)
“Contribution to the development of applications of lasers in Analytical Chemistry”
Supervisors: María Celia García-Álvarez-Coque and Guillermo Ramis-Ramos
University of Valencia (Spain), July 1993
Chemistry teacher at Secondary school
M.A. Rius-Revert, M.C. García-Álvarez-Coque, G. Ramis-Ramos, “Disproportionation and thermal lens effects produced by Ar+ laser radiation on silver halide suspensions”. Analytica Chimica Acta 292, 113–120 (1994).
E.F. Simó-Alfonso, M.A. Rius-Revert, M.C. García-Álvarez-Coque, G. Ramis-Ramos, “Reduction of convective low-frequency noise in thermal lens spectrometry”. Applied Spectroscopy 44, 1501–1507 (1990).
Ernesto Francisco Simó-Alfonso
(from University of Valencia, Spain)
“Design, construction and optimisation of a thermal lens spectrometer to perform static and flow measurements”
Supervisors: María Celia García-Álvarez-Coque and Guillermo Ramis-Ramos
University of Valencia (Spain), April 1992
PhD grant, Dirección General de Innovación, Ciencia y Tecnología (DGICYT) of Spain (January 1989–December 1992)
Post-doctorate stay with Prof. Pier Giorgio Righetti at the Department of Agricultural and Industrial Biotechnology, University of Verona (Italy), granted with a Marie Curie Fellowship (ERC Council).
Associate Professor, Professor and currently Full Professor at the Department of Analytical Chemistry, University of Valencia (Spain).
G. Ramis-Ramos, J.J. Baeza-Baeza, E.F. Simó-Alfonso, “A model for optical saturation thermal lens spectrometry”. Analytica Chimica Acta 296, 107–113 (1994).
J.S. Esteve-Romero, E.F. Simó-Alfonso, M.C. García-Álvarez-Coque, G. Ramis-Ramos, “Conventional and thermal lens spectrophotometric determination of p-aminobenzoic acid and arylamine diuretics previous azodye formation in a micellar medium”. Talanta 40, 1711–1718 (1993).
E. Simó-Alfonso, Y. Martín-Biosca, M.C. García-Álvarez-Coque, G. Ramis-Ramos, “On the use of mixing reactors in flow injection analysis with thermal lens calorimetric detection”. Thermochimica Acta 219, 53–64 (1993).
E.F. Simó-Alfonso, M.C. García-Álvarez-Coque, G. Ramis-Ramos, A. Cladera-Forteza, M. Estela-Ripoll, V. Cerdá-Martín, “An automatic system for thermal lens spectrometry and flowing samples”. Analytical Letters 25, 573–592 (1992).
E.F. Simó-Alfonso, M.A. Rius-Revert, M.C. García-Álvarez-Coque, G. Ramis-Ramos, “Reduction of convective low-frequency noise in thermal lens spectrometry”. Applied Spectroscopy 44, 1501–1507 (1990).
J.S. Esteve-Romero, E.F. Simó-Alfonso, M.C. García-Álvarez-Coque, G. Ramis-Ramos, “Determination of aniline in vegetable oils by diazotization and coupling in a microemulsion medium”. Analytica Chimica Acta 235, 317–322 (1990).
María José Medina-Hernández
(from University of Valencia, Spain)
“Study and analytical applications of the reactions of cystine, cysteine and N‑acetyl-L-cysteine with o-phthalaldehyde”
Supervisors: María Celia García-Álvarez-Coque and Carlos Mongay-Fernández
University of Valencia (Spain), February 1989
PhD grant, Generalitat Valenciana (September 1986–August 1989)
PhD. award
Associate Professor, Professor and currently Full Professor at the Department of Analytical Chemistry, University of Valencia (Spain)
M.J. Medina-Hernández, E. Bonet-Domingo, R.M. Villanueva-Camañas, M.C. García-Álvarez-Coque, “Use of the o-phthalaldehyde and N-acetyl-L-cysteine reagent in the evaluation of milk proteins”. Journal of Dairy Sciences 74, 1779–1785 (1991).
M.J. Medina-Hernández, R.M. Villanueva-Camañas, E. Monfort-Cuenca, M.C. García-Álvarez-Coque, “Determination of the protein and free amino acid content in a sample using o‑phthalaldehyde and N-acetyl-L-cysteine”. Analyst 115, 1125–1128 (1990).
M.J. Medina-Hernández, E. Bonet-Domingo, R.M. Villanueva-Camañas, M.C. García-Álvarez–Coque, “Evaluation of the proteolysis degree with the o-phthalaldehyde/N-acetyl-L-cysteine reagent”. Fresenius Journal of Analytical Chemistry 338, 62–65 (1990).
M.J. Medina-Hernández, R.M. Villanueva-Camañas, M.C. García-Álvarez-Coque, “Determination of total free amino acids with o-phthalaldehyde and N-acetyl-L-cysteine”. Microchemical Journal 42, 288–293 (1990).
M.J. Medina-Hernández, M.C. García-Álvarez-Coque, E. Bonet-Domingo, R.M. Villanueva-Camañas, “FIA‑spectrophotometric assay of N-acetylcysteine by o-phthalaldehyde derivatization”. Pharmazie 45, 745–747 (1990).
M.C. García-Álvarez-Coque, M.J. Medina-Hernández, R.M. Villanueva-Camañas, C. Mongay-Fernández, “Spectrophotometric determination of N-acetylcysteine in drug formulations with o‑phthalaldehyde and isoleucine”. Analyst 114, 975–977 (1989).
M.C. García-Álvarez-Coque, M.J. Medina-Hernández, R.M. Villanueva-Camañas, C. Mongay-Fernández, “Studies on the formation and stability of isoindoles derived from amino acids, o‑phthalaldehyde and N-acetyl-L-cysteine”. Analytical Biochemistry 180, 172–176 (1989).
M.C. García-Álvarez-Coque, M.J. Medina-Hernández, R.M. Villanueva-Camañas, C. Mongay-Fernández, “Formation and instability of o-phthalaldehyde derivatives of amino acids” (review). Analytical Biochemistry 178, 1–7 (1989).
M.J. Medina-Hernández, R.M. Villanueva-Camañas, M.C. García-Álvarez-Coque, “Spectrophotometric determination of cystine by formation of an o-phthalaldehyde/N-acetyl-L-cysteine derivative”. Microchemical Journal 40, 292–296 (1989).
M.C. García-Álvarez-Coque, M.J. Medina-Hernández, R.M. Villanueva-Camañas, C. Mongay-Fernández, “Some observations on the reaction of cysteine with o-phthalaldehyde”. Spectrochimica Acta Part A 44, 1461–1464 (1988).
M.C. García-Álvarez-Coque, M.J. Medina-Hernández, R.M. Villanueva-Camañas, C. Mongay-Fernández, “Spectrophotometric determination of cystine with o-phthalaldehyde in the absence of thiol”. Analytical Letters 21, 1545–1559 (1988).
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