Glucose Regulation Project

The project SEP-CONACYT-ANUIES-ECOS NORD 296692 (2019-2024):

 “New Generation of Closed-Loop Control Algorithms for Glucose Regulation in Diabetic Patients via Bio-Inspired Models” 

is a bilateral research collaboration between CITEDI-IPN, Mx., and the IMS Laboratory of the University of Bordeaux, Fr. The project pursues the design of new closed-loop glucose regulation algorithms in Diabetes Mellitus Type 1 patients. We consider commercial continuous glucose monitoring systems and alternative biosensors measuring the pancreatic islets' electric activity. The project also comprises students and researchers from the Tecnológico Nacional de México/I.T. La Laguna. 

This project tries to address an international and national scope problem in health.  

Publications

JCR Journals

1. R. Franco, A. Ferreira de Loza, H. Ríos, L. Cassany, D. Gucik-Derigny, J. Cieslak, D. Henry and L. Olçomendy. “Output Feedback Sliding-Mode Controller for Blood Glucose Regulation in Critically Ill Patients affected by Type 1 Diabetes”. IEEE Transactions on Control Systems Technology 29(6), 2021, pp. 2704–2711.

2. R. Franco, H. Ríos, A. Ferreira de Loza, L. Cassany, D. Gucik-Derigny, J. Cieslak and D. Henry. “Parameter Identification and State Estimation for a Diabetic Glucose-Insulin Model via an Adaptive Observer”. International Journal of Robust and Nonlinear Control 33(9), 2023, pp. 5087–5104. 

3. L. Olçomendy, L. Cassany, A. Pirog, R. Franco, E. Puginier, M. Jaffredo, D. Gucik-Derigny, H. Ríos, et al. “Towards the integration of an islet–based biosensor in closed–loop therapies for patients with Type 1 Diabetes”. Frontiers in Endocrinology 13, 2022, 795225. 

Book Chapters

4. R. Franco, H. Ríos, A. Ferreira de Loza, L. Cassany, D. Gucik–Derigny, J. Cieslak and D. Henry. “Blood Glucose Regulation for Type 1 Diabetic Patients at Intensive Care Unit via Continuous Sliding–Mode Algorithms”. Sliding–Mode Control and Variable–Structure Systems. Studies in Systems, Decision and Control, Springer, Cham, Vol. 490, 2023, pp. 385–416.

International Conferences

5. L. Cassany, D. Gucik-Derigny, J. Cieslak, D. Henry, R. Franco, A. Ferreira de Loza, H. Ríos, L. Olçomendy, A. Pirog, Y. Bornat, S. Renaud and B. Catargi. “A Robust Control solution for Glycaemia Regulation of Type-1 Diabetes Mellitus”. In the 2021 European Control Conference, Rotterdam, Netherlands, 2021, pp. 327-332.

6. L. Cassany, D. Gucik-Derigny, J. Cieslak, D. Henry, R. Franco, A. Ferreira de Loza, H. Ríos, L. Olçomendy, A. Pirog, Y. Bornat, S. Renaud and B. Catargi. “A Robust  Control Approach for Blood Glucose Regulation in Type-1 Diabetes”. In the 11th IFAC Symposium on Biological and Medical Systems, Ghent, Belgium, 2021, pp. 460–465. 

7. R. Franco, H. Ríos, A. Ferreira de Loza, D. Efimov, L. Cassany, D. Gucik-Derigny, J. Cieslak and D. Henry. “Blood Glucose Regulation in Patients with Type 1 Diabetes Mellitus: A Robust MRAC Approach”. In the 60th IEEE Conference on Decision and Control, Austin, Texas, USA, 2021, pp. 661–666. 

8. D. Henry, J. Cieslak, D. Gucik–Derigny, A. Ferreira de Loza and H. Ríos. “Further results on “non individualized” closed–loop for T1DM patients”. In the 2023 IEEE Conference on Control Technology and Applications, Bridgetown, Barbados, 2023, pp. 892–897. 

9. H. Ríos, M. Mera, and A. Ferreira de Loza. “An Interval Predictor–based Robust Controller for the Blood Glucose Regulation Problem”. In the IEEE 63rd Conference on Decision and Control 2024, Milan, Italy, 2024, pp. 1370–1375.

National Conferences

10. R. Franco, A. Ferreira de Loza, H. Ríos, L. Cassany, D. Gucik-Derigny, J. Cieslak, D. Henry and L. Olçomendy. “Regulación de Glucosa en la Sangre en Pacientes con Diabetes Mellitus Tipo 1 usando Control por Realimentación de Salida”. In the 27° Congreso Argentino de Control Automático AADECA’20 Virtual, pp. 58-63.

11. R. Franco, H. Ríos, A. Ferreira de Loza, L. Cassany, D. Gucik-Derigny, J. Cieslak and D. Henry. “Adaptive Estimation for an Insulin–Glucose Model”. In the 2021 Congreso Nacional de Control Automático, Guanajuato, México, pp. 1–5.

12. R. Franco, H. Ríos, A. Ferreira de Loza, D. Efimov, L. Cassany, D. Gucik-Derigny, J. Cieslak and D. Henry. “Robust Model Reference Adaptive Control for an Insulin–Glucose Model”. In the 2021 Congreso Nacional de Control Automático, Guanajuato, México, pp. 154–159.

13. H. Ríos, M. Mera, and A. Ferreira de Loza. “Blood Glucose regulation with Hypoglycemic Avoidance: An Interval–Predictor Approach”. In the 2024 Congreso Nacional de Control Automático, Ciudad de México, México, pp. 61–66.

Dissemination Journals

14. A. Ferreira de Loza, H. Ríos and R. Franco. “Páncreas Artificial: Un Paso Hacia la Gestión Eficiente de la Diabetes”. Revista Digital Universitaria (RDU) 24(5), 2023 (septiembre–octubre), pp. 1–11.