Neuroscience
The Preventative Effects of Career Type and Alzheimer’s Disease
Nick Gettinger
Neuroscience
Nick Gettinger
Alzheimer’s disease (AD) is the most common form of dementia, with over 45 million people affected worldwide. One in three adults will have the disease by age 85, with no current form of prevention or counteractant. AD is defined as a gradual onset of neurodegeneration in several areas of cognition in the brain. There are two main pathologies of AD: amyloid beta plaques and tau neurofibrillary tangles. In a healthy brain, amyloid beta and tau are vital to cell growth and repair. When amyloid-beta and tau proteins become dysfunctional and aggregated, they accumulate within the brain and neurons, prohibiting nerve function and damaging nerve cells, leading to a loss of cognitive and memory function. A database of 200 clinically impaired patients ages 70-80 results of positron emission tomography scans and cognitive recall tests will be analyzed. Patients will be separated into 5 groups based off of careers (science and math, arts and humanities, language and education, human services, and manual labor) and the correlation between career type and neurological degeneration will be determined.