University Hospitals Coventry and Warwickshire NHS Trust 

Commercial Capabilities

SPECIALIST SERVICES

• 32 Specialties across the whole trust, including paediatrics & neonatal

• Renal Transplant Centre 

SPECIALIST FACILITIES & EQUIPMENT

• Research Treatment Centre

• Inpatient and Overnight Research Unit

• Biomedical Research Unit

• Human Metabolism Research Unit

• Arden Tissue Bank

• Patient Research Interface Suites

• Dedicated Clinical Trials Pharmacy 

• Bod Pod Service

• Two of the world’s most advanced Whole Body Calorimeters

• Sleep monitoring equipment- Alice PDX sleepware system 

• Olink technology for targeted and discovery proteomics

• Nanostring platform for  tissue (frozen and FFPE) spatial profiling and multi-omics 

CHIEF INVESTIGATOR/PRINCIPAL  INVESTIGATOR EXPERTISE

We have a multi-disciplinary clinical research delivery teams supporting a range of specialties throughout the Trust, at both University Hospitals Coventry and Warwickshire NHS Trust, as well as St Cross in Rugby. These include:

• Anaesthetics

• Cardiology

• Dermatology

• Diabetes (WISDEM)

• Emergency & Critical care

• Endocrine

• Gastroenterology

• Haematology

• Hepatology

• Human Metabolism Research Unit (HMRU)

• Infectious Diseases

• Neurology

• Oncology (Cancer)

• Ophthalmology

• Paediatrics & Neonatal

• Palliative care

• Renal

• Reproductive Health (Biomedical Research Unit/Centre for Reproductive Medicine)

• Respiratory

• Rheumatology

• Stroke

• Surgery

• Trauma & Orthopaedics

• Urology

• Vascular

AREAS KEEN TO GROW

• Phase 1 and 2 research due to the overnight facility and our Clinical Research Facility

RECRUITMENT ACHIEVEMENTS 

• Intrepid Commercial trial (Gastro) 1st UK recruited patient

• First UK patient screened 28th June 

• ADAPT-1 study - First UK patient recruited 6th July

• Our Research Treatment Centre and Inpatient Research Unit provides the dedicated facilities, support and expertise required to conduct high quality early phase clinical research

• The Inpatient Research Unit includes two inpatient beds, en-suite bathroom facilities and a nurse station and is designed to accommodate early phase interventional studies and high-intensity or high-complexity elements of later phase studies

• The Research Treatment Centre includes a treatment area for outpatients or day patients comprising six treatment chairs, a participant toilet and nurse station.  The Centre has a welcoming participant reception and waiting area, a drug storage and preparation area, as well as a centrifuge room, all with continuous temperature monitoring

• Our dedicated CRF staff are experienced in delivering experimental treatments for research participants and hold appropriate life support qualifications

• Our highly skilled clinical research delivery team include health scientists, pathologists, radiographers and nurses who work collaboratively to deliver high quality research.

• With a combination of highly skilled clinical and non-clinical expertise, our team possess experience working on a diverse portfolio of research projects, including commercial, non-commercial, and grant-funded studies.

• We have established collaborations with several leading commercial sponsors, strengthening our research experience. Some of our collaborators include:

• Novo Nordisk

• Debiopharm

• Crinetics Pharmaceuticals

• Boehringer Ingelheim

• Camurus AB

• bbott Diabetes

• Eli Lilly and Company

• Ascendis Pharma

•  Valneva Austria GmbH

• Innocoll Pharmaceuticals

• Sanofi Group

• Mereo BioPharma

• AstraZeneca

• We also work in partnership with universities, industry, and other partners to develop research within the Trust.

WISDEM Centre

• WISDEM provides quality care for patients with diabetes, endocrine and other metabolic conditions, as well as actively engaging in cutting-edge research, encompassing clinical studies in diabetes and metabolism. Our team, led by Professor Harpal Randeva, comprises over 30 dedicated researchers and clinicians.  Professor Randeva has been involved in over 40 research projects as a Principal Investigator, spanning from Phase I to Phase III. Additionally, he has served as the Chief Investigator for three studies.

• Our research team has conducted studies in various areas, including diabetes, obesity, cardiovascular or chronic kidney disease, non-alcoholic fatty liver disease, polycystic ovary syndrome, acromegaly, growth hormone deficiency, neuroendocrine tumours, male hypogonadism, adrenal insufficiency, and diabetic foot ulcers.

• Moreover, we have consistently surpassed our recruitment targets for most of our studies, positioning us as top recruiters in the United Kingdom. Our exceptional track record in recruitment has gained recognition, as we have been invited to share our experience in recruitment and retention at various meetings.

Research 

Team