Team 8

Endo-Lectrode: An
Endovascular Electroencephalographic Electrode Device For Neurocritical Care and Epilepsy


Team Members: Emily Hanzlick
Dorothy Palomares
Alexis Ratliff
Anthony Silva
Jacob Schuler

Team Mentors: Bradley Greger, PhD - SBHSE
Todd Abruzzo, MD - Phoenix Children's Hospital

YouTube Link: View the video link below before joining the zoom meeting

Zoom Link: https://asu.zoom.us/j/83563963288


Abstract

When a patient does not respond well to a number of different medications prescribed to them by a doctor, the next option the patient faces is a surgical procedure where a physician will remove the part of their brain causing the seizures in the first place. This process begins with a number of imaging techniques in order to establish the part of the brain causing the condition. Currently, this source localization is done via depth electrodes or subdural ECoG (Electrocorticography). Both of these methods involve the disruption of several different elements of the head and brain, each with their own distinctive function. We believe it is time for a newer technology that mitigates this disruptive nature of these traditional methods. We plan to develop a retrievable neuroendo electrode device that can be implanted and removed via a transvascular catheter and guidewire system into the vessels located around the brain. This device will have an array of electrodes that will go through the process of identifying abnormalities in electrical brain activity. Data processing will be accomplished via a component of the device implanted within a patient's chest cavity and wirelessly communicated to an external device. Currently, we have developed a physical prototype on a macro-scale to show the feasibility of such a technology. In our model, we are able to localize the source of activity through agar gel using our device. We also have several virtual models establishing important factors such as force modeling, wireless communication, and theory for source localization.