Team 20
A Hydrogel Delivery System for Ecm Growth Factors that Provides Necessary Moisture and Antimicrobial Resistance that Promotes Tissue Regeneration for Burn Wounds
A Hydrogel Delivery System for Ecm Growth Factors that Provides Necessary Moisture and Antimicrobial Resistance that Promotes Tissue Regeneration for Burn Wounds
Team Members: Tatyana Gonzalez
Taylor Miller
Selena Rodriguez
Liana Soto
Team Mentors: Apollo Arquiza, PhD - SBHSE
Jessica Weaver, PhD - SBHSE
Kaitlyn Libraro, MS, MPA, RN - William Randolph Hearst Burn Center
Andrew Neading, BSN, RN - MetroHealth, Humabiologics, and Katecho, LLC
YouTube Link: View the video link below before joining the zoom meeting
Zoom Link: https://asu.zoom.us/j/8481710788
Abstract
The capstone project goal is to create a hydrogel bandage for burn wounds that will maintain a sterile, moist environment, and promote tissue regeneration. The unmet customer needs that were identified by Andrew Neading, RN BSN, the Burn Program Coordinator at MetroHealth Medical Center, and Kaitlyn Libraro, MS, MPA, RN of William Randolph Hearst Burn Center, was a bandage that can adhere to curved surfaces and reduce the amount of times the bandages need to be changed. The design concept that was generated to solve this problem uses a hydrogel loaded with Epidermal growth factors and antimicrobial agents with an adhesive edge. The hydrogel base is made of agarose for its flexibility, absorption properties, and tensile strength. The hydrogel will provide the needed moisture for tissue development and a physical barrier for infections and environmental damage. The hydrogel can be loaded with beneficial material to promote tissue regeneration. Silver sulfadiazine is commonly used in creme treatments for burn injuries. Aloe vera treatments are also commonly used by burn survivors to provide moisture to the site of injury. The nurses that apply the treatment to burn injuries have limited time due to the volume or patients. Therefore, the application and removal process will need to be quick. As expressed by Mr. Neading, the patients are discharged as soon as they or their caretaker can dress their bandages. This was taken into consideration of the application and removal meaning that ease of use is very important for the patient.