Joseph Eisenberg
Carl Marrs, Lixin Zhang, Gabriel Trueba, William Cevallos Trujillo, James Trostle, Karen Levy, Alan Hubbard
Owen Solberg, Karina Ponce, Maria Ines Baquero, Pablo Endara, Maria Eloisa Hasing
National Institutes of Health
Rotavirus is the most common cause of acute gastroenteritis among infants and young children throughout the world, but rotavirus cases in developing countries account for nearly all of the approximately 600,000 annual deaths. In this community-based case-control study, we examined the epidemiology of rotavirus in 22 rural communities in northern coastal Ecuador over a five-year period. Additionally, a temporal analysis of the distribution of rotavirus genotypes was performed using samples from 22 rural communities in the northern coast and in a children's hospital in Quito between 2005 and 2007.