Escherichia coli Pathotype Genotyping

Principal Investigator

Joseph Eisenberg

Co-Investigators

Carl Marrs, Lixin Zhang, Gabriel Trueba, William Cevallos Trujillo, James Trostle, Karen Levy, Alan Hubbard

Additional Personnel

Sarah Bates, Owen Solberg, Karina Ponce, Nadia Vieira, Rebecca Howsmon, Lee Riley

Funding Sources

National Institutes of Health

About this Project

Enteroinvasive Escherichia coli (EIEC) causes dysentery; however, it is less widely reported than other etiological agents in studies of diarrhea worldwide. To examine EIEC infection rates in Ecuador, a community-based case-control study was conducted between August 2003 and July 2005. Stool samples were collected in case-control studies in 22 rural communities in northwestern Ecuador, and infection with EIEC was assessed using PCR techniques. Patterns of infection were compared with infections with Shigellae as well as enterotoxigenic (ETEC) and enteropathogenic (EPEC) E. coli.