How can I print a lot of drawing layout at one go?

Use command PUBLISH.

Spend a little bit time to study it.

You can even print all layouts in same paper size even they have different original paper size.

Use SHIFT key to select all layout, tick out "Model tab" to exclude all model spaces.

Create a template file and save various plot settings into it, ie. A1-A3_HalfPenWidth, or A1-A1_FullPenWidth.

Then when you use PUBLISH command, you can always IMPORT the plot ettings from your template file.

Another method is to create a SheetSet, add these layouts into the SheetSet, Right-click the SheetSet and select the right option to print them all.

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