Symptoms: Abnormal behaviour, affective lability, agitation, amnesia, anxiety, blindness, blurred vision, coma, confusion, constipation, convulsions, delirium, diarrhea, dry mouth, dry mucous membranes, dry skin, dysarthria, euphoria, fever, flaccid paralysis, flight of ideas, fluctuating levels of attention, fluctuating levels of comprehension, fluctuating levels of consciousness, fluctuating levels of fluency, fluctuating levels of orientation, flushing, hallucinations, headaches, high blood pressure, incoherent speech, incoherent thoughts, light-headedness, loss of accommodation, low blood pressure, mental alterations, mydriasis, nausea, nervousness, nervous system depression, paralysis, respiratory failure, respiratory irritation, salivation, seizures, sweating, tachycardia, tangential thinking, thirst, urinary retention, vomiting, weakness, zombie-like state.
Duration of Symptoms: Hours - weeks depending on the symptoms, with treatment.
Rate of Poison: Within 5 - 10 minutes.
Causes Death: Yes
Treatment: Activated charcoal, gastric lavage, physostigmine via intravenous route.
While these plants may resemble the trumpet of an angel, these plants are far from saintly. Consumption of around ten flowers can result in intoxication or death, with the effects of the poison almost immediate.
Photo: D. A. Wilkerson
Molecular structure of atropine (ChemDraw)
Atropine is known to be an anticholinergic blocking agent by acting as an antagonist to the acetylcholine receptor. It can also be defined as an antimuscarinic agent, which acts as an antagonist to muscarine, such as acetylcholine. To do this, atropine binds to the residues of the acetylcholine receptor, and prevents acetylcholine from binding to the receptor. By suppressing the action of acetylcholine, the activation of the parasympathetic nervous system is reduced.
Level of Toxin: 0.3 mg per blossom.
Impacting Dosage: 10 mg
Hyoscyamine is an alkaloid derivative from atropine and exhibits anticholinergic activity. Like atropine, hyocyamine acts as an antagonist to acetylcholine receptors, which suppresses the activation of the parasympathetic nervous system. Hyoscyamine is easily hydrolyzed to tropine and tropic acid.
Level of Toxin: Varies
Impacting Dosage: Greater than 1.5 mg/day
Molecular structure of hyoscyamine (ChemDraw)
Molecular structure of scopolamine (ChemDraw)
Scopolamine is an antagonist for acetylcholine receptors and is a tropane alkaloid. Scopolamine blocks the receptors located on smooth muscle cells structures that are supplied by the postganglionic cholinergic nerves. Just like hyocyamine and atropine, scopolamine mimicks the activity of acetylcholine receptors and suppresses the activation of the parasympathetic nervous system.
Level of toxin: 0.65 mg per blossom, 3 mg throughout.
Impacting Dosage: 1.2 ng/mL
Parts of Plant: All parts.
Contact Hazard: Sap can cause rash on skin.
Animals Affected: Most animals
*Hummingbirds are unaffected.
Parts of Plant: All parts
Properties: Anesthetic, anthelmintic, anti-amoebic, anti-dermal pathogenic fungi, antifungal, anti-inflammatory, antioxidant, aphrodisiac, emetic, enema, reduction of morphine withdrawl, sedative, spasmolytic, stimulant
Components: Scopolamine
Antidote: Helps treat people with cocaine, morphine, and opioid abuse.
Preparation: Infusion, oils, ointment, poultice, tincture.
Aches and pains
Arthritis
Dermatitis
Headaches
Herbal Medicine: Indigenous people used Angel's Trumpet as herbal medicine and for religious ceremonies.
Infections
Rheumatism
South America: Used angel's trumpet to treat surface conditions like arthritis, dermatitis, aches and pains, and infections.
Arthritis: Ointment used to treat arthritic pain. Boiling water infusion/ethanol tincture.
Asthma: Ayurvedic medicine; inhaling burning leaves to treat asthma.
Boils: Leaves made into a poultice accelerates breakdown of boils.
Burns: Ointment used to treat burns.
Colds
Cramps
Dandruff
Dermatitis
Ears: Oils mixed with other herbs are applied to ears to relieve pain.
Fever: Fruit mixed and burned with cow dung, then crushed, to treat fevers that are caused by someone who has contracted malaria. Leaves used to alleviate fevers.
Headache
Hemorrhoids
Muscles
Pain: Flowers and seeds mixed in water and ingested to relieve pain. Leaves made into a poultice used to treat pain.
Rheumatism: Leaves used externally to relieve pain. Boiling water infusion/ethanol tinctures.
Skin Infection: Boiling water infusions/ethanol tinctures.
Stomach
Swelling: Boiling water infusions/ethanol tinctures.
Tumors: Leaves used to treat tumors.
Ulcers
Worms
Ayurveda: Arthritis, asthma, back pain, dandruff, sciatica, skin diseases, ulcers.
Chile: Leaves made into a poultice used to treat boils and pain.
Kinshasa, Democratic Republic of Congo: Leaves used as direct application, ointment. poultice, tincture. Plant treats aches and pains, dermatitis, headaches, muscle ailments, orchitis, stomach ailments.
Peru: Boiling water infusions/ethanol tinctures are used to treat arthritis, rheumatism, skin infection, and swelling. Leaves are used to treat boils, fevers, pain, and tumors.
Rio Grande do Sul: Mixed flowers and seeds into water to relieve pain..
Parts of Plant: Leaves, seeds.
Nutrients: None known
Taste: Bitter
WARNING: All beverages listed are created with the purpose of induction of psychosis.
Drink: In South America, drinks are used for religious purposes, such as evaluating one's true self or contacting with deities.
Beer: Tanzania; added to beer. Crushed seeds added to chicha
Chicha: Crushed seeds added to chicha (psychoactive beer)
Cimora: Peru; leaves added to psychoactive beverage along with the San Pedro cactus.
Illustration of Angel's Trumpet by D. A. Wilkerson
Family: Solanaceae (Nightshade Family)
Genus: Brugmansia
Other Names: Angel Star, Angel's Tears, Brazil's White Angel Trumpet, Cornucopia, Datura, Devil's Breath, Devil's Trumpet, Floripondio, Hindu Datura, Night Bells, Peruvian Trumpeta, Snowy Angel's Trumpet, Stramoine Inoffensive, Stramoine Parfumée, Tree Datura, Trompeta de Ángel, Trompette des Anges, Trompette du Jugement, Trumpet Flower, White Angel's Trumpet
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Bloom Colours: Pink, red, orange, cream, yellow, green[ish], pale violet, white.
Bloom Time: April - August
Type: Annual (perennial in more southern states).
Height: 3 - 30 feet
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Habitat: Deserts, dry rocky soil, moist soil, sand, tropical climates, woody areas. Human civilization.
*This plant is considered extinct in the wild, and can only really be seen in gardens for ornamental use.
Origin: South America, Andes Mountains.
States: CA, FL, IN, LA, MS, NM, TX
Provinces: MB, ON
Brugmansia arborea
(Common Angel's Trumpet)
Photo: D. A. Wilkerson
Brugmansia insignis
(Frosty Pink Angel's Trumpet)
Photo: Dinesh Valke - Wikimedia Commons
License: CCSA 2.0
Brugmansia sanguinea
(Red Angel's Trumpet)
Photo: Slick - Wikimedia Commons
Brugmansia suaveolens (Angel's Tears)
Photo: Rob Hille - Wikimedia Commons
Brugmansia versicolor (Arborescent Angel's Trumpet)
Photo: Wouter Hagens - Wikimedia Commons
Brugmansia x rubella
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National Center for Biotechnology Information (2022). PubChem Compound Summary for CID 3000322, Scopolamine. Retrieved July 18, 2022 from https://pubchem.ncbi.nlm.nih.gov/compound/Hyoscine.
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Date of page creation: September 1, 2022
Updated page: May 9, 2024