Chronic Lyme Disease- Symptom Lists
Chronic Lyme Disease: A Working Case Definition, Stricker RB, Fesler, MC
Table 1: Untreated chronic Lyme disease (CLD-U)*
Symptom/sign
Chest Pain
Fibrillation
Flutter
Murmur
Myocardial Infarction
Myocarditis
Myopericarditis
Muscle Atrophy
Synovitis
Tenosynovitis
Arthralgia (joint pain)
Arthritis
Dactylitis
Joint Warmth
Muscle Weakness
Musculoskeletal Pain
Periorbital Edema
Encephalomyelitis
Paraparesis
Encephalopathy
Neuropathy
Optic Neuritis
Transient Ischemic Attack
Blurred Vision
Eye Pain
Facial Pain
Fatigue
Headaches
Hypesthesia
Memory Difficulties
Photophobia
Progressive Visual Loss
Ptosis
Radicular Pain
Restriction of Visual Field
Tinnitus
Vertigo
Total: 37
*Symptoms and signs of chronic Lyme disease without antibiotic treatment (CLD-U). Symptoms/signs were associated with positive B. burgdorferi culture, PCR or microscopy.
Symptom/Sign Category
a) Musculoskeletal (%) - 23/59 (39)
b) Neuropsychiatric (%) - 29/59 (49)
c) Cardiovascular (%) - 7/59 (12)
Table 2: Chronic Lyme disease following limited antibiotic treatment (CLD-T)*
Symptom/sign
Muscle Atrophy
Fibromyalgia
Meningismus
Synovitis
Tenosynovitis
Arthralgia (joint pain)
Arthritis
Migratory Pain
Muscle Stiffness
Muscle Weakness
Musculoskeletal Pain
Myalgia
Torticollis
Trigger Finger
Dementia
Parkinsonism
Depressed Corneal Reflexes
Hemiparesis
Recurrent encephalomyeloradiculopathy
Trigeminal Sensory Neuropathy
Blunted Affect
Cognitive Dysfunction
Cogwheel Rigidity
Confusion
Decreased Central Vision
Decreased Verbal Fluency
Depression
Difficulty Naming Objects
Disorientation
Drooling
Fatigue
Fullness in head
Headaches
Hypalgesia
Hypesthesia
Impaired Judgment
Impaired Swallowing
Memory Difficulties
Numbness
Paresthesias
Perseveration
Poor Concentration
Poor Initiation
Radicular Pain
Tinnitus
Tremors
Vertigo
Total: 47
*Symptoms and signs of chronic Lyme disease following limited antibiotic treatment (CLD-T). Symptoms/signs were associated with positive B. burgdorferi culture, PCR or microscopy.
Symptom/Sign Category:
a) Musculoskeletal (%) - 24/73 (33)
b) Neuropsychiatric (%) - 49/73 (67)
c) Cardiovascular (%) - 0/73 (0)