Chemistry

The Armstrong lab studies "Chromatographic Separations and Analysis: Cyclodextrin-Mediated High-Performance Liquid Chromatography, Gas Chromatography and Capillary Electrophoresis Enantiomeric Separations."

Learn more and how to join at: https://www.uta.edu/academics/faculty/profile?user=sec4dwa

The Buonomo Lab engages in research at the interface of chemistry, biology, and engineering. We deploy aspects of these disciplines to create technologies that enable the discovery of novel therapeutics, diagnostic platforms, and to facilitate basic scientific inquiry.

Learn more and how to join at: https://www.jabuonomo.com/

Our laboratory focuses on mass spectrometry-based method development in the following specific areas of proteomics. The focused biological application of our research is to understand the role of Toll-like Receptors (TLRs)/NOD-like Receptors (NLRs) in inflammatory signaling pathways. We focus on studying several environmental diseases impacted by innate immunity, such as atherosclerosis, sepsis, cancer, etc. by mass spectrometry-based novel proteomics tools. In addition, the approaches we develop can be generally applied to any biological systems; hence we also welcome researchers to initiate collaborative research efforts with us.

Learn more and how to join at: https://proteomics-lab.uta.edu/

Instrumentation for Extraterrestrial Exploration, Open tubular ion and liquid chromatography and development of detectors for the same, Mathematical methods to reduce dispersion and perform quantitation and identification, Dynamic imaging of chromatographic columns, Nonlinear absorbance amplification in multipath broadband spectroscopy. Destruction of PFAS and Measurement as fluoride. Automated Intelligent Analyzers, Microfabricated sensors and Instrumentation, Thin Film Flow Devices and Sensors, Automated Process Analyzers for the Chemical Industry, Novel Approaches to Ionic Analysis, Ion Behavior at High Field Strengths

Learn more: https://www.uta.edu/academics/faculty/profile?user=dasgupta

Thank you for visiting the Dias Group website.  We are a synthetic chemistry group specializing in inorganic and organometallics chemistry at the University of Texas at Arlington. We focus on uncovering and developing powerful catalysts for small molecule activation, energy efficient processes for olefin-paraffin separation, molecules that are luminescent, strategies for controlling ethylene effects in plants, and methodologies for stabilizing reactive intermediates. We create specific metal complexes for desired applications, and design and use new fluorinated ligands and anions widely in our research.

We value diversity and welcome students from different educational backgrounds with interests in scientific discovery. 

Learn more and how to join: https://diasgroup.uta.edu/

Thank you for visiting our website. Our group is interested in biomimetic design and synthesis of soft nanomaterials. Our research benefits from our expertise in peptide-based molecular and supramolecular chemistry. We synthesize peptides with both natural and non-natural amino acids and develop new methodology for self-assembly of these peptides toward functional nanomaterials. 

Learn more and how to join: https://dong-group.uta.edu/

Our research interests span diverse topics in Bioorganic and Organic Chemistry. Inquiry within our laboratory is performed through organic synthesis. The rest of the time, we do whatever it takes to design our molecules and characterize and analyze their desired function.

Currently, we are interested in the following areas of research:

• Biomimetic/Bioinspired Oxidation Chemistry

• Materials for Drug Discovery

• Novel Targets for Anti-Infectives

• Green Chemistry

• Heterocyclic Chemistry

Learn more and how to join: https://fosslab.uta.edu/

Explorations of autocatalytic features of Son of Sevenless (SOS) and NADPH oxidase (Nox) and their deregulations to cause Noonan syndrome and leukemia: The research objective of this project is to determine the unique autocatalysis mechanisms of SOS and Nox, respectively, and how their dysregulations are linked to the developments of Noonan syndrome and leukemia.

Investigations of the role of the embryonic Ras in human tumors: The research objective of this project is to determine the role of unprecedented Embryonic Ras (ERas) in human tumors.

Mechanistic Studies of the immunosuppressive effects of thiopurines: The research objective of this project is to determine the therapeutic mechanism of 6-thiopurine (6-TP) drugs associated with redox-sensitive small GTPases for autoimmune disorders such as Inflammatory Bowel Disease.

Learn more and how to join: https://www.uta.edu/academics/faculty/profile?user=jheo

Our research program at the University of Texas at Arlington involves synthetic organic chemistry and organometallic chemistry.  The goal of our research is to develop direct, more streamlined, and sustainable catalytic methods to synthesize transformative molecules with significant functions and to advance our understanding of the associated catalytic mechanisms.  Benefits which accrue from our multi-disciplinary research projects include the introduction of sustainable chemical synthesis and catalysis fields to high school, undergraduate, and graduate students’ STEM education. 

Learn more and how to join: https://www.junhajeon.org/

The conducted research within her group spans from molecular biology techniques, such as polymerase chain reaction (pcr) and site-directed mutagenesis, to protein expression and purification. The Johnson-Winters group interests include mechanistic studies of F420 cofactor dependent enzymes, using kinetic isotope effects methods, as well as steady-state and pre-steady state kinetic methods. This class of enzymes is unique, involving specifically hydride transfer reactions. The F420 cofactor has implications with tuberculosis disease (TB), folate biosynthesis, antibiotic biosynthesis and energy production.

Learn more and how to join: https://www.uta.edu/academics/faculty/profile?user=kayunta

Amorphous Ceramics and Glasses

Structure and Function of Polymer-Derived Ceramics (PDCs)

High-Temperature Ceramics based on SiC and Si3N4

Oxidation processes of UHTC

Thermochemistry of Silicate Glasses

High-Pressure Science

Prediction of new Compounds

Computation of Phase diagram

Structural Phase Transitions

Learn more and how to join: https://www.uta.edu/academics/faculty/profile?user=pkroll

My research focuses on the unique chemistry that only rare-earth elements can provide in solid-state materials. Because rare-earth elements possess core f-electrons, rare-earth based materials exhibit a diverse array of intriguing physical phenomena that translate into optical, magnetic, and semiconducting applications. Our research activity is focused on synthesis and understanding of how changing the crystal chemistry of rare-earth solid-state materials can lead to control of physical behavior.

Learn more and how to join: https://macalusolab.uta.edu/team/

Heterogeneous catalysis with a focus on fuel forming reactions. I am specifically focused on the development and improvement of cobalt-based Fischer-Tropsch catalysts for the production of N-alkanes, heterogeneous catalysts related to the water-gas shift reaction for hydrogen production, and the use aluminum for hydrogen production.

Learn more: https://www.uta.edu/academics/schools-colleges/science/departments/chemistry/faculty

The ultimate goal of my laboratory is to understand the fundamental mechanism of various human diseases including inflammatory diseases, metabolic diseases, cardiovascular diseases, neurological disorders, and cancer, and develop effective diagnosis and treatments.

We have two major lines of projects:

Chromatin Modifications and noncoding RNAs in Gene Regulation, Epigenetics, inflammation, steroid hormone signaling, and Human Disease. We study in-depth cell signaling biology and biochemistry using cultured cells, animal models, and patient sample analysis.

Medicinal Chemistry and Drug discovery: Develop (deign, synthesis and screen) novel organic molecules and enzyme inhibitors targeting macrophage activation, inflammation, cardiovascular diseases and cancer (immunotherapy).

Learn more and how to join: https://mandal-lab.uta.edu/

One approach is to introduce an otherwise non-toxic prodrug that can be activated to destroy tumors and tumor vasculature. In our group we develop such compounds, using light energy to switch on the drug: confining the light treatment to only the affected area allows for spatial and temporal targeting of diseased tissue while minimizing damage to healthy tissue. The energy of the incident light promotes the compound — the photosensitizer — to an electronically excited state that can undergo subsequent chemical processes involving energy and/or electron transfer reactions. If oxygen is present, these reactions can generate cytotoxic reactive oxygen species, such as singlet oxygen, which is the defining characteristic of photodynamic therapy (PDT).

Learn more and how to join: https://mcfarlandlabs.uta.edu/

Mechanism-Based Computational Strategies for Enzyme Design and Engineering

Hydrogen storage in salt caverns: Molecular dynamics simulations of hydrogen diffusion

Learn more and how to join: https://www.uta.edu/academics/faculty/profile?user=kwangho.nam#About%20Me

We are interested in studying main group compounds with electron-deficient systems, ranging from the fundamental design of molecules for molecular recognition to their diverse applications in materials and biomedicine. Our interest extends beyond just Lewis acidic main group compounds; we aim to investigate all types of main group compounds across many different fields. Ultimately, our goal is to advance the field of main group chemistry by exploring into unknown territories.

Learn more and how to join: https://parklab.uta.edu/

I am interested in the analysis of compounds of environmental concern. This includes the use of commercial instrumentation for analysis of environmental or biological samples but also the development of new instruments that may outperform or more cheaply perform the same analysis. The latter requires a multidisciplinary approach from circuit design, fabrication, programming, and data processing. Currently my lab is focused on the detection of perfluoroalkylsubstances (PFAS). One projects is looking at gestational PFAS exposure for infants and affects on birth outcomes. Another is developing a miniature total organic fluorine analyzer that is capable of measuring the emitted fluoride after degradation of PFAS. We are also utilizing electrodialysis with functional membranes for the recovery of metals and other critical minerals from recycled materials as well as recovery of proteins from cell lysates for further analysis.

Learn more and how to join: https://www.uta.edu/academics/faculty/profile?user=shelor#About%20Me

We study how the assembly and regulation of small nuclear ribonucleoprotein complexes (snRNPs) control co-transcriptional gene expression and how their misregulation contributes to human diseases. Our research integrates molecular biology, RNA biochemistry, and cancer biology to understand how cells build and regulate RNA-Protein machinery that governs gene expression. 

Learn more and how to join: https://solab.uta.edu/