exercise, even if it is inside the cell (Fovet et al., 2020; Hewson et al., 2020). Although access to hygiene measures can be difficult, the prisoners should be constantly informed about the social distancing precautions and provided with accurate information about the pandemic, in order to reduce anxiety and improve adherence to the restricting measures (Hewson et al., 2020; Tozzo et al., 2020). Concluding Remarks COVID-19 pandemic brings novel challenges to human beings. Not only virus’ spread and disease mortality for risk groups, but also emotional, behavioral and psychological impact to the population. Measures to contain disease transmission, including quarantine, social isolation and social distancing may affect the population’s behavior and may lead to psychological disorders. Several emotional and psychological conditions including fear, anxiety, depression, and suicide ideation are triggered by the pandemic itself as well as by the adopted preventive measures. Special attention should be paid to vulnerable groups both in regard to prevent harmful emotional repercussions of the pandemic, but also to provide the necessary assistance. The health authorities and the governments should strategize to alleviate the mental burden of COVID-19 pandemic by providing emotional support to the entire population, but particularly to the vulnerable individuals. ALP and LB equally contributed to this article as first authors, both authors made the literature revision and selection of main articles for this review, defined the topics of this review, and wrote the first draft. ACFF, MLBC, RGBC, and SBCSB helped in writing specific topics of the review and helped in search and analysis of clinical trials included in this review. ACSS conceptualized the study, made general supervision, revised the manuscript, and submitted the final version of the manuscript, which is approved by all authors. Funding The authors acknowledge the Brazilian National Funding Agencies, CAPES and CNPq (Grant # 302153/2019-5) for financial support. Conflict of Interest The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. Abstract Background Novel virus outbreaks, such as the COVID-19 pandemic, may increase psychological distress among frontline workers. Psychological distress may lead to reduced performance, reduced employability or even burnout. In the present study, we assessed experienced psychological distress during the COVID-19 pandemic from a self-determination theory perspective. Methods This mixed-methods study, with repeated measures, used surveys (quantitative data) combined with audio diaries (qualitative data) to assess work-related COVID-19 experiences, psychological need satisfaction and frustration, and psychological distress over time. Forty-six participants (nurses, junior doctors, and consultants) completed 259 surveys and shared 60 audio diaries. Surveys and audio diaries were analysed separately. Results Quantitative results indicated that perceived psychological distress during COVID-19 was higher than pre-COVID-19 and fluctuated over time. Need frustration, specifically autonomy and competence, was positively associated with psychological distress, while need satisfaction, especially relatedness, was negatively associated with psychological distress. In the qualitative, thematic analysis, we observed that especially organisational