understanding of the benefits of MRMT®, especially in direct comparison to alternative therapeutic approaches. Conclusions Given the prevalence and burden of chronic pain due to FM and other conditions, the individualized and multilayered assessment approach of MRMT®may hold considerable promise for pain reduction and functional improvements for many patients struggling to find relief. This noninvasive process has the potential to reduce burden on primary care providers while improving patient well-being. The use of manual therapies in the treatment of chronic pain is still debated by the scientific and medical communities, but our study shows that if manual therapy is tailored to the patient and used to educate the patient, then physical function and quality of life can be improved, leading to fewer pain symptoms and better overall health. References 1. Sugerman DT (2014) JAMA patient page. Fibromyalgia. JAMA 311: 1577. 2. Rahman A, Underwood M, Carnes D (2014) Fibromyalgia. BMJ 348: g1224. 3. Marques AP, Santo ASDE, Berssaneti AA, Matsutani LA, Yuan SLK (2017) Prevalence of fibromyalgia: literature review update. Rev Bras Reumatol Engl Ed 57: 356-363. 4. Lachaine J, Beauchemin C, Landry PA (2010) Clinical and economic characteristics of patients with fibromyalgia syndrome. Clin J Pain 26: 284-290. 5. Thompson JM, Luedtke CA, Oh TH, Shah ND, Long KH, et al. (2011) Direct medical costs in patients with fibromyalgia: Cost of illness and impact of a brief multidisciplinary treatment program. Am J Phys Med Rehabil 90: 40-46. 6. Häuser W, Thieme K, Turk DC (2010) Guidelines on the management of fibromyalgia syndrome - a systematic review. Eur J Pain 14: 5-10. 7. Sarzi-Puttini P, Atzeni F (2014) Fibromyalgia: a never-ending story of central and peripheral pain mechanisms. Arthritis Rheumatol 66: 1687-1688. 8. Higgs JB (2018) Fibromyalgia in Primary Care. Prim Care 45: 325-341. 9. Clauw DJ (2014) Fibromyalgia: a clinical review. JAMA 311: 1547-1555. 10. Ablin J, Fitzcharles MA, Buskila D, Shir Y, Sommer C, et al. (2013) Treatment of fibromyalgia syndrome: Recommendations of recent evidence-based interdisciplinary guidelines with special emphasis on complementary and alternative therapies. Evid Based Complement Alternat Med 2013: 485272. chronic pain due to FM complicated by the additional challenges associated with diabetes. The MRMT® process incorporates a structured assessment before each treatment to allow therapists to better determine a patient’s status, including the patient’s perception of current pain and function, and customize treatment and self-care education at each visit so that they are both effective and acceptable to the patient. A goal of MRMT is that patients who complete the treatment plan will be better equipped physically and emotionally to deal with their pain as the intervention is tailored to the patient and has a focus on increasing the patient’s knowledge of their own condition, leading them to change unhealthy patterns of thought and behavior.