Product vs R.O.S

OXIDATIVE STRESS (O.S) CONTENT

STUDY TRAILS / TREATMENT EFFECTIVENESS AND RECOMMENDATIONS DOCUMENTED

Reference Links:

https://www.researchgate.net/search, https://www.mdpi.com/, https://pubmed.ncbi.nlm.nih.gov/, https://www.sciencedirect.com/   

Blood pH:

Alkaline Ionized Water.

Bone mineral density (BMD) and Osteoporosis:

Alkaline Ionized Water, Pantothenic acid Vitamin B5, Vitamin B6,  Cobalamin vitamin B12.

Inflammation, redox homeostasis:

Alkaline Reduced Water, Hydrogen Rich Water, Niacin Vitamin B3, Pantothenic acid Vitamin B5,

Pyridoxine Vitamin B6, Cobalamin vitamin B12.

Elevated ROS, Superoxide (O₂•−), Hydrogen Peroxide (H₂O₂), Hydroxyl Radical (HO•), Singlet oxygen (1O₂)

Elevated RNS, Nitric Oxide (NO•), Peroxynitrite (ONOO−), Nitrogen dioxide (NO₂)

Gastrointestinal (GI) disease, gastritis, IBD, Crohn’s disease, IBS, Ulcerative colitis:

Alkaline Reduced Water, Hydrogen Rich Water, L-ascorbic acid vit C, Pyridoxine Vitamin B6,

Cobalamin vitamin B12.

Elevated ROS, Superoxide anion (O2•-) and hydrogen peroxide (H2O2)

Elevated RNS, peroxynitrite (ONOO−), nitric oxide (NO)

Functional dyspepsia:

Alkaline Reduced Water, Cobalamin vitamin B12.

Elevated ROS, Superoxide (O₂•−), Hydrogen Peroxide (H₂O₂), Hydroxyl Radical (HO•)

Elevated RNS, Nitric Oxide (NO•), Peroxynitrite (ONOO−)

Acid reflux, Gastric hyperacidity:

Alkaline Reduced Water, Electrolytes infused Water.

Elevated ROS, such as Superoxide (O₂•−), Hydrogen Peroxide (H₂O₂), Hydroxyl Radical (HO•), Singlet oxygen (1O₂), Hypochlorous acid (HOCl), Peroxyl radical is (ROO•)

Elevated RNS like Nitric Oxide (NO•), Peroxynitrite (ONOO−)

Abnormal intestinal fermentation:

Alkaline Reduced Water, Niacin Vitamin B3, Pantothenic acid Vitamin B5, Pyridoxine Vitamin B6,

Cobalamin vitamin B12, Zinc Zn, Magnesium Mg.

Elevated ROS, Superoxide (O₂•−)

Elevated RNS, Nitric Oxide (NO•), Peroxynitrite (ONOO−)

Chronic diarrhoea:

Alkaline Reduced Water.

Elevated ROS, Superoxide (O₂•−), Hydrogen Peroxide (H₂O₂), Hydroxyl Radical (HO•)

Elevated RNS, Peroxynitrite (ONOO−)

Exercise-induced oxidative stress:

Alkaline Reduced Water, Hydrogen Rich Water, Electrolytes infused Water, Zinc Zn, Niacin Vitamin B3,

Pantothenic acid Vitamin B5, Pyridoxine Vitamin B6, Cobalamin vitamin B12, L-ascorbic acid Vitamin C.

Elevated ROS, Hydrogen Peroxide (H₂O₂), Hydroxyl Radical (HO•), Superoxide Anion (O2·-)

Elevated RNS, Peroxynitrite (ONOO−)

Low stamina:

Alkaline Reduced Water, Electrolytes infused Water, Niacin Vitamin B3, Pantothenic acid Vitamin B5,

Pyridoxine Vitamin B6, Cobalamin vitamin B12, L-ascorbic acid Vitamin C, Zinc Zn.

Elevated ROS, Hydrogen Peroxide (H₂O₂), Hydroxyl Radical (HO•)

Elevated RNS, Nitric Oxide (NO•), Peroxynitrite (ONOO−) 

Lack of mental clarity, pessimism, Depression:

Hydrogen Rich Water Niacin Vitamin B3, Pantothenic acid Vitamin B5, Pyridoxine Vitamin B6,

Cobalamin vitamin B12, L-ascorbic acid Vitamin C, Zinc Zn.

Elevated ROS, Hydrogen Peroxide (H₂O₂), Hydroxyl Radical (HO•)

Elevated RNS, Nitric Oxide (NO•), Peroxynitrite (ONOO−)

Soft tissue injury, muscle fatigue, function decline:

Alkaline Reduced Water, Hydrogen Rich Water, Electrolytes infused Water, Niacin Vitamin B3,

Pantothenic acid Vitamin B5, Pyridoxine Vitamin B6, L-ascorbic acid Vitamin C.

Elevated ROS, Hydrogen Peroxide (H₂O₂), Hydroxyl Radical (HO•)

Elevated RNS, Nitric Oxide (NO•), Peroxynitrite (ONOO−)

Reduced reactive oxygen metabolites in blood:

Alkaline Reduced Water, Hydrogen Infused Water, L-ascorbic acid vit C, Niacin Vitamin B3,

Pantothenic acid Vitamin B5, Pyridoxine Vitamin B6, Vitamin B12.

Elevated ROS, Hydrogen Peroxide (H₂O₂), Hydroxyl Radical (HO•)

Elevated RNS, Nitric Oxide (NO•), Peroxynitrite (ONOO−)

Metabolic Syndrome:

Alkaline Reduced Water, Hydrogen Rich Water, L-ascorbic acid Vitamin C, Niacin Vitamin B3,

Pyridoxine Vitamin B6, Cobalamin vitamin B12, Zinc Zn.

Elevated ROS, Hydrogen Peroxide (H₂O₂), Hydroxyl Radical (HO•)

Elevated RNS, Nitric Oxide (NO•), Peroxynitrite (ONOO−)

Diabetes mellitus:

Alkaline Reduced Water, Hydrogen Rich Water, L-ascorbic acid Vitamin C, Niacin Vitamin B3,

Pyridoxine Vitamin B6, Cobalamin vitamin B12, Zinc Zn, Magnesium Mg.

Elevated ROS, Hydrogen Peroxide (H₂O₂), Hydroxyl Radical (HO•)

Elevated RNS, Nitric Oxide (NO•), Peroxynitrite (ONOO−)

Atherogenesis diabetic complications:

Niacin Vitamin B3, Pantothenic acid Vitamin B5, Pyridoxine Vitamin B6, Cobalamin vitamin B12,

L-ascorbic acid Vitamin C, Zinc Zn.

Elevated ROS, Superoxide (O₂•−), Hydrogen Peroxide (H₂O₂), Hydroxyl Radical (HO•)

Elevated RNS, Nitric Oxide (NO•), Peroxynitrite (ONOO−)

Diabetic retinopathy, macular oedema:

Niacin Vitamin B3, Pantothenic acid Vitamin B5, Pyridoxine Vitamin B6, Cobalamin vitamin B12.

Elevated ROS, Superoxide (O₂•−), Hydrogen Peroxide (H₂O₂), Hydroxyl Radical (HO•)

Elevated RNS, Nitric Oxide (NO•), Peroxynitrite (ONOO−)

Diabetic neuropathy:

Hydrogen Rich Water, Pyridoxine Vitamin B6, Cobalamin vitamin B12.

Elevated ROS, Superoxide (O₂•−), Hydrogen Peroxide (H₂O₂)

Elevated RNS, Nitric Oxide (NO•), Peroxynitrite (ONOO−)

Diabetic nephropathy:

Pyridoxine Vitamin B6, Cobalamin vitamin B12, L-ascorbic acid.

Elevated ROS, Superoxide (O₂•−), Hydrogen Peroxide (H₂O₂), Hydroxyl Radical (HO•)

Elevated RNS, Peroxynitrite (ONOO−)

Reducing blood sugar, glycaemic control:

Alkaline Reduced Water, Hydrogen Rich Water, L-ascorbic acid.

Elevated ROS, Superoxide (O₂•−), Hydrogen Peroxide (H₂O₂), Hydroxyl Radical (HO•)

Elevated RNS, Peroxynitrite (ONOO−)

Insulin secretion: 

Pyridoxine Vitamin B6, L-ascorbic acid Vitamin C.

Elevated ROS, Superoxide (O₂•−), Hydrogen Peroxide (H₂O₂)

Elevated RNS, Nitric Oxide (NO•), Peroxynitrite (ONOO−)

Carbohydrate metabolism:

Niacin Vitamin B3, Pantothenic acid Vitamin B5, Pyridoxine Vitamin B6, Cobalamin vitamin B12.

Elevated ROS, Superoxide (O₂•−)

Elevated RNS, Nitric Oxide (NO•), Peroxynitrite (ONOO−)

Fatty liver disease, Obesity:

Hydrogen Rich Water, L-ascorbic acid Vitamin C. Pantothenic acid Vitamin B5.

Elevated ROS, Superoxide (O₂•−), Hydrogen Peroxide (H₂O₂), Hydroxyl Radical (HO•)

Elevated RNS, Nitric Oxide (NO•), Peroxynitrite (ONOO−)

Osteoarthritis (OA), Rheumatoid arthritis (RA), Chronic gouty arthritis:

Alkaline Reduced Water, Hydrogen Rich Water, L-ascorbic acid VitaminC, Zinc Zn, Niacin Vitamin B3,

Pyridoxine Vitamin B6.

Elevated ROS, Superoxide (O₂•−), Hydrogen Peroxide (H₂O₂), Hydroxyl Radical (HO•)

Elevated RNS, Nitric Oxide (NO•), Peroxynitrite (ONOO−)

Allergic rhinitis:

L-ascorbic acid Vitamin C.

Elevated ROS, Superoxide (O₂•−), Hydrogen Peroxide (H₂O₂), Hydroxyl Radical (HO•)

Elevated RNS, Nitric Oxide (NO•), Peroxynitrite (ONOO−)

Atherosclerosis:

Niacin Vitamin B3, Pantothenic acid Vitamin B5, Pyridoxine Vitamin B6, Cobalamin vitamin B12.

Elevated ROS, Superoxide (O₂•−), Hydrogen Peroxide (H₂O₂), Hydroxyl Radical (HO•), Hypochlorous acid (HOCl)

Elevated RNS, Nitric Oxide (NO•), Peroxynitrite (ONOO−)

Neuro degenerative, Parkinson's disease:

Hydrogen Rich Water, Pyridoxine Vitamin B6, Cobalamin vitamin B12.

Elevated ROS, Superoxide (O₂•−), Hydrogen Peroxide (H₂O₂), Hydroxyl Radical (HO•)

Elevated RNS, Nitric Oxide (NO•), Peroxynitrite (ONOO−), Nitrogen dioxide (NO₂)

Alzheimer's disease (AD), Dementia:

Niacin Vitamin B3, Pyridoxine Vitamin B6, Cobalamin vitamin B12, L-ascorbic acid Vitamin C.

Elevated ROS, Superoxide (O₂•−), Hydrogen Peroxide (H₂O₂), Hydroxyl Radical (HO•)

Elevated RNS, Nitric Oxide (NO•), Peroxynitrite (ONOO−)

Bradycardia / Pulse drop:

Hydrogen Rich Water, Electrolytes infused Water.

Niacin Vitamin B3, Pyridoxine Vitamin B6, Cobalamin vitamin B12,   L-ascorbic acid Vitamin C.

Elevated ROS, Superoxide (O₂•−), Hydrogen Peroxide (H₂O₂), Hydroxyl Radical (HO•)

Elevated RNS, Nitric Oxide (NO•), Peroxynitrite (ONOO−)

Endothelial inflammation, dysfunction:

Niacin Vitamin B3, Pyridoxine Vitamin B6, Cobalamin vitamin B12,   L-ascorbic acid Vitamin C.

Elevated ROS, Superoxide (O₂•−), Hydrogen Peroxide (H₂O₂), Hydroxyl Radical (HO•), Hypochlorous acid (HOCl)

Elevated RNS, Peroxynitrite (ONOO−)

Period acne, Acne vulgaris:

Alkaline Reduced Water, Niacin Vitamin B3, Pantothenic acid Vitamin B5, Pyridoxine Vitamin B6,

Cobalamin vitamin B12, Zinc Zn.

Elevated ROS, Superoxide (O₂•−), Hydrogen Peroxide (H₂O₂), Hydroxyl Radical (HO•)

Elevated RNS, Nitric Oxide (NO•), Peroxynitrite (ONOO−)

Apoptosis, Mitochondrial apoptosis:

Alkaline Reduced Water, Hydrogen Rich Water, Niacin Vitamin B3, Pantothenic acid Vitamin B5,

Pyridoxine Vitamin B6, Cobalamin vitamin B12, L-ascorbic acid.

Elevated ROS, Superoxide (O₂•−), Hydrogen Peroxide (H₂O₂), Hydroxyl Radical (HO•), Singlet oxygen (1O₂)

Elevated RNS, Nitric Oxide (NO•), Peroxynitrite (ONOO−)

Multiple sclerosis:

Hydrogen Rich Water, Niacin Vitamin B3, Vitamin B5, Vitamin B6, Cobalamin vitamin B12.

Elevated ROS, Superoxide (O₂•−), Hydrogen Peroxide (H₂O₂), Hydroxyl Radical (HO•), Hypochlorous acid (HOCl)

Elevated RNS, Nitric Oxide (NO•), Peroxynitrite (ONOO−)

Asthma:

Hydrogen Rich Water, Pyridoxine Vitamin B6, Cobalamin vitamin B12,   L-ascorbic acid Vitamin C, Zinc Zn.

Elevated ROS, Superoxide (O₂•−), Hydrogen Peroxide (H₂O₂), Hydroxyl Radical (HO•), Hypochlorous acid (HOCl)

Elevated RNS, Nitric Oxide (NO•), Peroxynitrite (ONOO−)

Chronic obstructive pulmonary disease:

Hydrogen Rich Water, L-ascorbic acid Vitamin C, Niacin Vitamin B3, Pyridoxine Vitamin B6,

Cobalamin vitamin B12, Zinc Zn, Magnesium Mg.

Elevated ROS, Superoxide (O₂•−), Hydrogen Peroxide (H₂O₂), Hydroxyl Radical (HO•), Hypochlorous acid (HOCl),

Elevated RNS, Nitric Oxide (NO•), Peroxynitrite (ONOO−), Nitrogen dioxide (NO₂), Lipid Peroxyl Radicals (ROO•)

Renal  /Kidney failure:

Niacin Vitamin B3, Pantothenic acid Vitamin B5, Pyridoxine Vitamin B6, Cobalamin vitamin B12,

L-ascorbic acid Vitamin C, Zinc Zn.

Elevated ROS, Superoxide (O₂•−), Hydrogen Peroxide (H₂O₂), Hydroxyl Radical (HO•)

Elevated RNS, Nitric Oxide (NO•), Peroxynitrite (ONOO−)

Metabolic rate:

Pyridoxine Vitamin B6, Cobalamin vitamin B12, L-ascorbic acid.

Elevated ROS, Superoxide (O₂•−), Hydrogen Peroxide (H₂O₂), Hydroxyl Radical (HO•), Singlet oxygen (1O₂)

Elevated RNS, Nitric Oxide (NO•), Peroxynitrite (ONOO−), Nitrogen dioxide (NO₂)

Uraemia:

Niacin Vitamin B3, Pyridoxine Vitamin B6, Cobalamin vitamin B12,   L-ascorbic acid Vitamin C.

Elevated ROS, Superoxide (O₂•−), Hydrogen Peroxide (H₂O₂), Hydroxyl Radical (HO•),

Advanced Glycated End Products (AGE), Reactive carbonyl Compounds (RCO)

Elevated RNS, Nitric Oxide (NO•), Peroxynitrite (ONOO−)

Cellular homeostasis:

Hydrogen Rich Water, Niacin Vitamin B3, Pantothenic acid Vitamin B5, Pyridoxine Vitamin B6,

Cobalamin vitamin B12, L-ascorbic acid Vitamin C.

Elevated ROS, Superoxide (O₂•−), Hydrogen Peroxide (H₂O₂), Hydroxyl Radical (HO•)

Elevated RNS, Nitric Oxide (NO•), Peroxynitrite (ONOO−)

Cholesterol level:     

Alkaline Reduced Water, Niacin Vitamin B3, Pantothenic acid Vitamin B5, Pyridoxine Vitamin B6,

Cobalamin vitamin B12, L-ascorbic acid Vitamin C.

Elevated ROS, Superoxide (O₂•−)

Elevated RNS, Nitric Oxide (NO•)

Hypertension:

Alkaline Reduced Water, Hydrogen Rich Water, Pyridoxine Vitamin B6,   L-ascorbic acid Vitamin C

Elevated ROS, Superoxide (O₂•−), Hydrogen Peroxide (H₂O₂), Hydroxyl Radical (HO•)

Elevated RNS, Nitric Oxide (NO•), Peroxynitrite (ONOO−)

Immune Response:

Hydrogen Rich Water, Niacin Vitamin B3, Pantothenic acid Vitamin B5, Pyridoxine Vitamin B6, Cobalamin vitamin B12, 

L-ascorbic acid Vitamin C, Zinc Zn, Magnesium Mg

Elevated ROS, Superoxide (O₂•−), Hydrogen Peroxide (H₂O₂), Hydroxyl Radical (HO•), Hypochlorite (ClO−)

Elevated RNS, Nitric Oxide (NO•), Peroxynitrite (ONOO−), Nitrogen dioxide (NO₂)

Insulin resistance:

Hydrogen Rich Water, Pyridoxine Vitamin B6

Elevated ROS, Superoxide (O₂•−), Hydrogen Peroxide (H₂O₂), Hydroxyl Radical (HO•)

Elevated RNS, Nitric Oxide (NO•), Peroxynitrite (ONOO−)

Tuberculosis:

Pyridoxine Vitamin B6, Cobalamin vitamin B12, L-ascorbic acid.

Elevated ROS, Superoxide (O₂•−), Hydrogen Peroxide (H₂O₂), Hydroxyl Radical (HO•), Hypochlorous acid (HOCl),

Elevated RNS, Nitric Oxide (NO•), Peroxynitrite (ONOO−), Nitrogen dioxide (NO₂)

Senescence / Aging:

Hydrogen Rich Water, Niacin Vitamin B3, Cobalamin vitamin B12,   L-ascorbic acid Vitamin C

Elevated ROS, Superoxide (O₂•−), Hydrogen Peroxide (H₂O₂), Hydroxyl Radical (HO•)

Elevated RNS, Nitric Oxide (NO•), Peroxynitrite (ONOO−), Nitrogen dioxide (NO₂)

Colon:

Alkaline Reduced Water, Hydrogen Rich Water, Niacin Vitamin B3, Vitamin B5, Vitamin B6, Cobalamin vitamin B12.

Elevated ROS, Superoxide (O₂•−), Hydrogen Peroxide (H₂O₂), Hydroxyl Radical (HO•)

Elevated RNS, Nitric Oxide (NO•), Peroxynitrite (ONOO−)