發表與成果（Publications & Achievements）

期刊論文（Publications）

1. Ti Lin, Shang-Lin Yang, Chao-Jung Chen, Pei-Fen Liu (2025, June). Unveiling the Potential Binding Targets of Celastrol in Colorectal Cancer: A Proteomic Profiling Approach Integrating Cellular Thermal Shift Assay and Pulse Proteolysis. Journal of Proteome Research, 24: 3174 - 3187.

2. Chun-Yen Chiu, Shih-Yu Huang, Jason T.C. Tzen, Pei-Fen Liu (2025, May). Mechanism of pancreatic lipase inhibition by strictinin purified from Pu'er tea. Food Bioscience, 69: 106954

3. Jhih-Jyun Hong, Chuan-Mei Yeh, Chia-Ming Lin, Ying-Shao Lu, Pei-Jun Wen, Pei-Fen Liu (2024, Jun). Functional Food for Sarcopenia: Investigating the Impact of Myostatin Epitope Fusion Protein in Elderly Mice using Probiotic Bacillus subtilis. Food Biotechnology, 38(2): 195-213. 

4. 劉沛棻（2022年06月）。差異化教學與師博課在教學上的結合應用：以生物化學為例。教學實踐研究，2(2), 27-52。教育部：教學實踐研究計畫。

5. Atikul Islam, Pei-Fang Hsieh, Pei-Fen Liu, Jou-Chun Chou, Jiunn-Wang Liao, Ming-Kun Hsieh, Pin Ju Chueh (2021, Sep). Capsaicin exerts therapeutic effects by targeting tNOX-SIRT1 axis and augmenting ROS-dependent autophagy in melanoma cancer cells. American Journal of Cancer Research, 11(9): 4199-4219.

6. Ying-Hsuan Tsai, Nakachew Minuye Mengesha, Pei-Fen Liu (2021, Mar). Identify the interactions between phytochemicals and proteins in the complicated food matrix. Food Chemistry, 356(10): 129641.  

7. Yu-Ting Huang, Pei-Chin Yeh, Shih-Chun Lan, Pei-Fen Liu (2020, Nov). Metabolites modulate the functional state of human uridine phosphorylase I. Protein Science, 29(11): 2189-2200. MOST 107-2311-B-005-002. 

8. Chin-Fang Chang, Atikul Islam, Pei-Fen Liu, Jun-Han Zhan, Pin Ju Chueh (2020, Oct). Capsaicin acts through tNOX (ENOX2) to induce autophagic apoptosis in p53-mutated HSC-3 cells but autophagy in p53-functional SAS oral cancer cells. American Journal of Cancer Research, 10(10): 3230–3247.

9. Yi-Sin Wong, Meei-Yn Lin, Pei-Fen Liu, Jiunn-Liang Ko, Guan-Ting Huang, Dom-Gene Tu, Chu-Chyn Ou (2020, Jun). D-methionine improves cisplatin-induced anorexia and dyspepsia syndrome by attenuating intestinal tryptophan hydroxylase 1 activity and increasing plasma leptin concentration. Neurogastroenterology & Motility, 32(6): e13803.

10. Pei-Fang Hsieh, Pin Ju Chueh, Pei-Fen Liu, Jiunn-Wang Liao, Ming-Kun Hsieh (2019, Apr). Immune response evoked by tumor-associated NADH oxidase (tNOX) confers potential inhibitory effect on lung carcinoma in a mouse model. American Journal of Cancer Research, 9(4): 740-751.

11. Yi-Kai Liu, Huei-Yu Chen, Pin Ju Chueh, and Pei-Fen Liu (2018, Dec). A one-pot analysis approach to simplify measurements of protein stability and folding kinetics. Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, 1867(3): 184-193. 

12. Huei-Yu Chen, Atikul Islam, Tien-Ming Yuan, Shi-Wen Chen, Pei-Fen Liu and Pin Ju Chueh (2018, Jul). Regulation of tNOX expression through the ROS-p53-POU3F2 axis contributes to cellular responses against oxaliplatin in human colon cancer cells. Journal of Experimental & Clinical Cancer Research, 37(1): 161.

13. Yi-Kai Liu, Tzu-Hsuan Lin, and Pei-Fen Liu. (2017, Nov). ATP alters protein folding and function of Escherichia coli uridine phosphorylase. Archives of Biochemistry and Biophysics, 634: 11-20. MOST 102-2311-B-005-009. 

14. Joseph Kasper, Pei-Fen Liu and Chiwook Park (2014, Dec). Structure of a Partially Unfolded Form of Escherichia coli Dihydrofolate Reductase Provides Insight into its Folding Pathway. Protein Science, 23(12): 1728-1737.

15. Pei-Fen Liu and Chiwook Park (2012, Sep). Selective Stabilization of a Partially Unfolded Protein by a Metabolite. Journal of Molecular Biology, 422, 403-413. 

16. Pei-Fen Liu and Chiwook Park (2011, Apr). Energetics-Based Discovery of Protein–Metabolite Interactions on a Proteomic Scale. Journal of Molecular Biology, 408, 147-162. 

17. Pei-Fen Liu, Larisa Avramova, and Chiwook Park (2009, Jun). Revisiting Absorbance at 230 nm as a Protein Unfolding Probe. Analytical Biochemistry, 389, 165-170. 

18. Li-Fun Liu, Chu-Hwai Hsieh, Pei-Fen Liu, Sia-Pei Tsai, and Ming F. Tam (2004, Jun). Escherichia coli Methionine Aminopeptidase with Tyr168 to Alanine Substitution can Improve the N-terminal Processing of Recombinant Proteins with Valine at the Penultimate Position. Analytical Biochemistry, 329, 345-347.

19. Pei-Fen Liu, Cheng Li, Yui-Huai Hsieh, Sen-Wei Chen, Su-Huai Chen, and Woei-Jer Chuang (2002, Dec). Solution Structure of the DNA-binding Domain of Interleukin Enhancer Binding Factor 1 (FOXK1a). Proteins, 49(4), 543-553. 

20. Woei-Jer Chuang, I-Ju Yeh, Yui-Huai Hsieh, Sen-Wei Chen, Pei-Fen Liu, Wen-Yi Jeng (2002, Sep). 1H, 15N and 13C Resonance Assignments for the DNA-binding Domain of Myocyte Nuclear Factor (Foxk1). Journal of Biomolecular NMR, 24(1), 75-76.