Publication

•2025 SCI-E Inhibition of mTOR attenuates the initiation and progression of BRCA1-associated mammary tumors: CANCER COMMUNICATIONS. :~ (20.1)

•2024 SCI-E Galectin-9 Mediates the Functions of Microglia in the Hypoxic Brain Tumor Microenvironment: CANCER RESEARCH. 84(22):3788~3802 (12.5)

•2024 SCI-E TIM-3 on myeloid cells promotes pulmonary inflammation through increased production of galectin-3: COMMUNICATIONS BIOLOGY. 7:1090~ (5.2)

•2023 SCI-E Immune Checkpoint-Blocking Nanocages Cross the Blood-Brain Barrier and Impede Brain Tumor Growth: ACS BIOMATERIALS SCIENCE & ENGINEERING. 10(1):575~587 (5.8)

•2022 SCI-E Adipocyte HIF2a functions as a thermostat via PKACa regulation in beige adipocytes: NATURE COMMUNICATIONS. 13(1):3268~ (17.694)

•2022 SCI-E A host non-coding RNA, nc886, plays a pro-viral role by promoting virus trafficking to the nucleus: MOLECULAR THERAPY-ONCOLYTICS. 24:683~694 (6.311)

•2021 SCI-E Local adenoviral delivery of soluble CD200R-Ig enhances antitumor immunity by inhibiting CD200-b-catenin-driven M2 macrophage: MOLECULAR THERAPY-ONCOLYTICS. 23:138~150 (7.2)

•2021 SCI-E Nc886, a Novel Suppressor of the Type I Interferon Response Upon Pathogen Intrusion: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 22(4):2003~ (5.924)

•2021 SCI-E Preclinical evaluation of radiation therapy of BRCA1-associated mammary tumors using a mouse model: INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES. 17(3):689~701 (6.582)

•2021 SCI-E Anticancer nanocage platforms for combined immunotherapy designed to harness immune checkpoints and deliver anticancer drugs: BIOMATERIALS. 270:120685~ (12.479)

•2021 SCI-E Modulation of Nogo receptor 1 expression orchestrates myelin-associated infiltration of glioblastoma: BRAIN. 144(2):636~654 (13.501)

•2020 SCI-E Glial TIM-3 Modulates Immune Responses in the Brain Tumor Microenvironment: CANCER RESEARCH. 80(9):1833~1845 (9.727)

•2019 SCI Glial TLR2-driven innate immune responses and CD8+ T cell activation against brain tumor: Glia. 67(6):1179~1195 (5.829)

•2018 SCI Loss of BRCA1 Spontaneously Induces the Tumorigenesis in Lacrimal Gland: Analytical Cellular Pathology. 2018:8~8 (1.574)

•2018 SCI Cyclin B1 stability is increased by interaction with BRCA1, and its overexpression suppresses the progression of BRCA1-associated mammary tumors: EXPERIMENTAL & MOLECULAR MEDICINE. 50(10):136~136 (5.584)

•2018 SCI Inhibition of Estrogen signaling reduces the incidence of BRCA1-associated mammary tumor formation: INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES. 14(12):1755~1768 (4.057)

•2018 SCI JIB-04, A small molecule histone demethylase inhibitor, selectively targets colorectal cancer stem cells by inhibiting the Wnt/B-catenine signaling pathway: SCIENTIFIC REPORTS. 2018(8):66111~66111 (4.122)

•2017 SCI-E CHK2 is involved in the p53-independent radiosensitizing effects of valproic acid: Oncology Letters. 13(4):2591~2598 (1.39)

•2017 SCI Glatiramer acetate attenuates the activation of CD4+ T cells by modulating STAT1 and -3 signaling in glia: Scientific Reports. 7:40484~40484 (4.259)

•2016 SCI-E nc886, a non-coding RNA and suppressor of PKR, exerts an oncogenic function in thyroid cancer: Oncotarget. 7(46):75000~75012 (5.008)

•2015 SCI Distinctive responses of brain tumor cells to TLR2 ligands:: Glia. 63(5):894~905 (6.031)

•2015 SCI The HIF-1/glial TIM-3 axis controls inflammation-associated brain damage under hypoxia.: Nature communications [electronic resource]. 6:6340~6340 (11.47)

•2015 SCI Anti-neuroinflammatory effects of DPTP, a novel synthetic clovamide derivative in in vitro and in vivo model of neuroinflammation.: Brain research bulletin. 112:25~34 (2.718)

•2014 SCI-E EOP, a Newly Synthesized Ethyl Pyruvate Derivative, Attenuates the Production of Inflammatory Mediators via p38, ERK and NF-κB Pathways in Lipopolysaccharide-Activated BV-2 Microglial Cells.: Molecules. 19(12):19361~19375 (2.095)

•2013 SCI-E Resveratrol Confers Protection against rotenone-induced neurotoxicity by modulating myeloperoxidase levels in glial cells: PLos One. 8(4):e60654~60654 (3.73)

•2013 SCI-E Regulation of microglia activity by glaucocalyxin-a: attenuation of lipopolysaccharide-stimulated neuroinflammation through NF-kB and p38 MAPK signaling pathways: PLos One. 8(2):e55792~e55792 (3.73)

•2012 SCI Ubiquitination and degradation of the FADD adaptor protein regulate death receptor-mediated apoptosis and necrotopsis: nature communications. 3:978~982 (7.396)

•2011 SCI Dual Functionality of Myeloperoxidase in rotenone-exposed brain-resident immune cells: American Journal of Pathology. 179(2):964~979 (5.224)

•2010 SCI Galectin-3 exerts cytokine-like regulatory actions through the JAK-STAT pathway: Journal of Immunology. 185(11):7037~7046 (5.646)

•2010 SCI Inflexin attenuates proinflammatory responses and nuclear factor kappa B activation in LPS-treated microglia: European Journal of Pharmacology. 633(1-3):98~106 (2.585)

•2009 SCI Twist2 regulates CD7 expression and galectin-1-induced apoptosis in mature T cells: Molecules and Cells. 28:533~558 (2.023)

•2009 SCI-E Expression Profiling of Neuroinflammatory Genes in LPS and LPS/IFNgamma-stimulated BV2 microglia cells: Biochip Journal. 3:299~305 (0.65)

•2009 SCI-E Genome-wide Inspection of Chromosomal Aberrations in Microglia BV-2 Cells by Array-based Comparative Genomic Hybridization: Biochip Journal. 3:28~36 (0.65)

•2008 SCI Sulfatide, a major lipid component of myelin sheath, activates inflammatory responses as an endogenous stimulator in brain-resident immune cells: Journal of Immunology. 181:8077~8087 (6.068)

•2008 SCI Regulation of TLR2 expression by prostaglandins in brain glia.: Journal of Immunology. 180(12):8400~8409 (6.068)

•2008 SCI Contribution of TLR2 to the initiation of ganglioside-triggered inflammatory signaling: Molecules and Cells. 25:99~104 (1.916)

•2006 SCI Induction of microglial apoptosis by corticotropin-releasing hormone.: Journal of Neurochemistry. 98:962~972 (4.604)

•2006 SCI Gangliosides trigger inflammatory responses via TLR4 in brain glia.: American Journal of Pathology. 168:1619~1630 (6.946)

•2005 SCI Double-stranded RNA-activated protein kinase is required for the LPS-induced activation of STAT1 inflammatory signaling in rat brain glial cells: Glia. 50:66~79 (4.781)

•2004 SCI Rac1 Contributes to Maximal Activation of STAT1 and STAT3 in IFN--Stimulated Rat Astrocytes: Journal of Immunology. 2004:5697~5703 (6.702)

•2003 SCI Curcumin suppresses Janus kinase-STAT inflammatory signaling through activation of Src homology 2 domain-containing tyrosine phosphatase 2 in brain microglia: Journal of Immunology. 171:6072~6079 (6.702)

•2003 SCI 15d-PGJ2 and rosiglitazone suppress Janus kinase-STAT inflammatory signaling through induction of suppressor of cytokine signaling 1 (SOCS1) and SOCS3 in glia: Journal of biological Chemistry. 278:14747~14752 (7.68)

•2002 SCI A glucose-inducible gene in Schizosaccharomyces pombe, rrg1+, is involved in negative regulation of G2/M progression: Mol Cells. 14:312~317 (1.872)

•2002 SCI JAK-STAT Signaling Mediates Gangliosides-induced Inflammatory Responses in Brain Microglial Cells: Journal of Biological Chemistry. 277:40594~40601 (7.68)

•2002 SCI Interleukin-13 and -4 induce death of activated microglia: Glia. 38:273~280 (4.78)

•2001 SCI Reactive oxygen species mediate A[beta](25-35)-induced activation of BV-2 microglia. Reactive oxygen species mediate A[beta](25-35)-induced activation of BV-2 microglia.: NeuroReport. 12:1449~1452 (2.7)

•1999 SCI Characterization of a novel mouse cDNA, ES18, involved in apoptotic cell death of T-cells.: Nucleic Acid Research. 27:1524~1530