2024
Nishimura A, Yoon S, Matsunaga T, Ida T, Jung M, Ogata S, Morita M, Yoshitake J, Unno Y, Barayeu U, Takata T, Takagi H, Motohashi H, van der Vliet A, Akaike T. Longevity control by supersulfide-mediated mitochondrial respiration and regulation of protein quality. Redox Biol. 2024 Feb;69:103018. doi: 10.1016/j.redox.2023.103018.
Hayasaka K, Takeda H, Sakurada A, Matsumura Y, Abe J, Shiono S, Notsuda H, Suzuki H, Endo M, Motohashi H, Okada Y. Clinical, Genomic, and Transcriptomic Featurses of Lung Adenocarcinoma With Uncommon EGFR Mutation. Clin Lung Cancer. 2024 Jan;25(1):e43-e51. doi: 10.1016/j.cllc.2023.10.006.
2023
Alam MM, Kishino A, Sung E, Sekine H, Abe T, Murakami S, Akaike T*, Motohashi H*. Contribution of NRF2 to Sulfur Metabolism and Mitochondrial Activity. Redox Biol 60, 102624, 2023. doi: 10.1016/j.redox.2023.102624. (*co-correspondence)
Takeda H, Nakajima Y, Yamaguchi T, Watanabe I, Miyoshi S, Nagashio K, Sekine H, Motohashi H, Yano H, Tanaka J. The anti-inflammatory and anti-oxidative effect of a classical hypnotic bromovalerylurea mediated by the activation of NRF2. J Biochem mvad030, 2023. doi: 10.1093/jb/mvad030.
Zainol Abidin QH, Ida T, Morita M, Matsunaga T, Nishimura A, Jung M, Hassan N, Takata T, Ishii I, Kruger W, Wang R, Motohashi H, Tsutsui M, Akaike T. Synthesis of Sulfides and Persulfides Is Not Impeded by Disruption of Three Canonical Enzymes in Sulfur Metabolism. Antioxidants (Basel) 12(4), 868, 2023. doi: 10.3390/antiox12040868.
Ikeda R, Noshiro D, Morishita H, Takada S, Kageyama S, Fujioka Y, Funakoshi T, Komatsu-Hirota S, Arai R, Ryzhii E, Abe M, Koga T, Motohashi H, Nakao M, Sakimura K, Horii A, Waguri S, Ichimura Y, Noda NN, Komatsu M. Phosphorylation of phase-separated p62 bodies by ULK1 activates a redox-independent stress response. EMBO J. 2023 Jul 17;42(14):e113349. doi: 10.15252/embj.2022113349.
Matsunaga T, Sano H, Takita K, Morita M, Yamanaka S, Ichikawa T, Numakura T, Ida T, Jung M, Ogata S, Yoon S, Fujino N, Kyogoku Y, Sasaki Y, Koarai A, Tamada T, Toyama A, Nakabayashi T, Kageyama L, Kyuwa S, Inaba K, Watanabe S, Nagy P, Sawa T, Oshiumi H, Ichinose M, Yamada M, Sugiura H, Wei FY, Motohashi H*, Akaike T*. Supersulphides provide airway protection in viral and chronic lung diseases. Nat Commun. 2023 Jul 25;14(1):4476. doi: 10.1038/s41467-023-40182-4. (*co-correspondence)
Takeda H, Murakami S, Liu Z, Sawa T, Takahashi M, Izumi Y, Bamba T, Sato H, Akaike T, Sekine H, Motohashi H*. Sulfur metabolic response in macrophage limits excessive inflammatory response by creating a negative feedback loop. Redox Biol. 2023 Jul 29;65:102834. doi: 10.1016/j.redox.2023.102834.
Kasamatsu S, Nishimura A, Alam MM, Morita M, Shimoda K, Matsunaga T, Jung M, Ogata S, Barayeu U, Ida T, Nishida M, Nishimura A, Motohashi H*, Akaike T*. Supersulfide catalysis for nitric oxide and aldehyde metabolism. Sci Adv. 2023 Aug 18;9(33):eadg8631. doi: 10.1126/sciadv.adg8631. (*co-correspondence)
Hayasaka K, Ohkouchi S, Saito-Koyama R, Suzuki Y, Okazaki K, Sekine H, Watanabe T, Motohashi H*, Okada Y*. Aging exacerbates murine lung ischemia-reperfusion injury by excessive inflammation and impaired tissue repair response. Am J Transplant. 2023 Sep 19:S1600-6135(23)00692-5. (*co-correspondence)
Murakami S, Kusano Y, Okazaki K, Akaike T, Motohashi H. NRF2 signalling in cytoprotection and metabolism. Br J Pharmacol. 2023 Sep 15. doi: 10.1111/bph.16246. Epub ahead of print. PMID: 37715470.
Barayeu U, Sawa T, Nishida M, Wei FY, Motohashi H, Akaike T. Supersulfide biology and translational medicine for disease control. Br J Pharmacol. 2023 Oct 23. doi: 10.1111/bph.16271. Epub ahead of print. PMID: 37872133.