Innovative Biomedical Devices and Integrated Systems 

Biosensors and Biosystems

This research area focuses on the integration of electrical, mechanical, and chemical sensing to create precise diagnostic platforms suitable for various biomedical and environmental applications.

Key Research Topics:

• Drug-Induced Cardiotoxicity Evaluation Platform
  We are developing multimodal sensor systems capable of simultaneously measuring mechanical contractions and electrical activity of cardiomyocytes in real time. These platforms enable early detection of cardiovascular side effects during drug development and serve as critical tools for preclinical cardiotoxicity screening.

• 3D Implantable Passive Wireless Biosensors
  Our team is working on implantable biosensors that operate passively and wirelessly, allowing for continuous monitoring of physiological signals without the need for internal power sources. These sensors can monitor parameters such as pressure, stress, or tissue responses over extended periods.

• Wearable Biosensors
  We design and fabricate flexible, stretchable wearable sensors that can be directly attached to the skin to monitor physiological signals such as heart rate and sweat biomarkers in real time. These technologies support personalized healthcare and continuous health monitoring.

• Electronic Nose Systems
  We develop highly sensitive gas sensor arrays capable of detecting complex volatile organic compounds (VOCs), forming the basis for electronic nose systems. These systems can identify specific odor patterns and are applicable in disease diagnosis, food freshness assessment, and environmental monitoring.

• Bio-implantable Scaffolds
  We are also working on bio-implantable scaffolds that integrate tissue (or bone) regeneration and sensing or therapeutic functions. These scaffolds, fabricated from biocompatible and biodegradable materials, are designed to support cellular growth while enabling functions such as electrical stimulation, pressure or stress monitoring, and localized drug delivery. 

Technical Highlights:

• Simultaneous quantification of electrical and mechanical signals for enhanced diagnostic accuracy

• Passive and wireless implantable sensors for long-term, low-maintenance monitoring

• Human-friendly, wearable materials for improved user comfort and compatibility

• Multi-sensor integration and AI-based pattern recognition for intelligent data analysis

The Biosensors and Biosystems research area aims to develop next-generation smart biosensing platforms with applications across healthcare, pharmaceuticals, diagnostics, and environmental monitoring, playing a key role in advancing intelligent biointerfaces.