Plasmonic Sensing & Imaging Platform

Our Plasmonic Platform leverages localized surface plasmon resonance (LSPR) and photonic nanostructures for ultra-sensitive biosensing and imaging applications. We develop label-free, optical detection systems capable of probing biomolecular interactions, tissue properties, and disease markers at unprecedented spatial and temporal resolution.

Relevant Publications

1. Kang H, Jeong S, Park Y, Yim J, Jun B-H, Kyeong S, Yang J-K, Kim G, Hong S, Lee LP, Kim J-H, Lee H-Y, Jeong DH, Lee Y-S. Near-infrared SERS nanoprobes with plasmonic Au/Ag hollow-shell assemblies for in vivo multiplex detection. Adv Funct Mater. 2013;23(30):3719–27.

2. Kang H, Yang J-K, Noh MS, Jo A, Jeong S, Lee M, Lee S, Chang H, Lee H, Jeon S-J, Kim H-I, Cho M-H, Lee H-Y, Kim J-H, Jeong DH, Lee Y-S. One-step synthesis of silver nanoshell with bumps for highly sensitive near-IR SERS nanoprobes. J Mater Chem B. 2014;2(28):4415-21.

3. Chang H, Kang H, Ko E, Jun B-H, Lee H-Y, Lee Y-S, Jeong DH. PSA detection with femtomolar sensitivity and a broad dynamic range using SERS nanoprobes and an area-scanning method. ACS Sensors. 2016;1(6):645-9.

4. Kang H, Koh Y, Jeong S, Jeong C, Cha MG, Oh M, Yang J-K, Lee H, Jeong DH, Jun B-H, Chang H, Kim Y-K, Lee Y-S. Graphical and SERS dual-modal identifier for encoding OBOC library. Sensor Actuat B-Chem. 2020;303:127211.

5. Kang H, Jeong S, Yang J-K, Jo A, Lee H, Heo EH, Jeong DH, Jun B-H, Chang H, Lee Y-S. Template-Assisted plasmonic nanogap shells for highly enhanced detection of cancer biomarkers. Int J Mol Sci. 2021; 22(4):1752.

6. Kim Y-H, Hahm E, Pham X-H, Kang H, Jeong D-H, Chang H, Jun B-H. Mercury Ion-Responsive Coalescence of Silver Nanoparticles on a Silica Nanoparticle Core for Surface-Enhanced Raman Scattering Sensing. ACS Appl Nano Mater. 2023;6(24):23469-76.

7.  Yoo K, Cho H-S, Kim J, Shin M, Chu J-S, Jang S, Bae H-J, Jung HS, Kang H, Jun B-H. Aptamer-Conjugated Multi-Quantum Dot-Embedded Silica Nanoparticles for Lateral Flow Immunoassay. Biosensors. 2025;15(1):54.

8. Chang H, Hur W, Kang H,* Jun B-H*. In vivo surface-enhanced Raman scattering techniques: nanoprobes, instrumentation, and applications. Light: Science & Applications. 2025;14(1):79.