DelveInsight's "Metastatic Uveal Melanoma Pipeline Insight 2025" report delivers extensive analysis on over 15 companies and more than 15 pipeline drugs in the Metastatic Uveal Melanoma treatment landscape. It includes thorough profiles of Metastatic Uveal Melanoma pipeline drugs, encompassing clinical and nonclinical development stages. Additionally, it evaluates therapeutics by product category, development phase, administration method, and molecular structure. It also points out discontinued pipeline products in this domain.
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Key Takeaways from the Metastatic Uveal Melanoma Pipeline Report
On August 29, 2025, the European Organisation for Research and Treatment of Cancer (EORTC) noted that at least 50% of patients with high-risk primary uveal melanoma face disease recurrence after primary tumor treatment. Currently, monitoring is the standard approach in the non-metastatic phase. Tebentafusp has become the first agent to show a survival advantage in metastatic uveal melanoma in a randomized trial. Based on this, it is proposed that tebentafusp could also lower recurrence risk in earlier-stage disease.
On August 22, 2025, IDEAYA Biosciences revealed a trial structured as a multi-stage Phase 2 within a Phase 3 to assess the safety, tolerability, pharmacokinetics, dose-exposure relationship, and anti-tumor effects of IDE196 combined with crizotinib versus the control arm of investigator-selected treatment (pembrolizumab, ipilimumab + nivolumab, or dacarbazine).
DelveInsight's Metastatic Uveal Melanoma Pipeline report illustrates a vibrant arena with over 15 active contributors developing more than 15 pipeline treatments for Metastatic Uveal Melanoma care.
The prominent Metastatic Uveal Melanoma Companies include Bristol-Myers Squibb, Merck & Co, Verastem Oncology, AstraZeneca, IDEAYA Biosciences, BioMed Valley Discoveries, Miltenyi Biomedicine GmbH, Vanquish Oncology, Hoffmann-La Roche, Linnaeus Therapeutics, and others.
Promising Metastatic Uveal Melanoma Pipeline Therapies include DYP688, Nivolumab, Relatlimab, ZIV-Aflibercept, Cemiplimab, IDE196, Crizotinib, Pembrolizumab, Binimetinib, Dacarbazine, and others.
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Metastatic Uveal Melanoma Emerging Drugs Profile
Nivolumab: Bristol-Myers Squibb Nivolumab (Opdivo, Opdyta) is a human IgG4 anti-PD-1 monoclonal antibody. Opdivo is available as a solution and concentrate for intravenous and subcutaneous administration. Nivolumab is approved for unresectable melanoma. Opdivo alone is for unresectable or metastatic melanoma with progression after ipilimumab and, if BRAF V600 positive, a BRAF inhibitor. Opdivo is for metastatic squamous non-small cell lung cancer (NSCLC) progressing on platinum-based chemotherapy. Opdivo with ipilimumab is for BRAF V600 wild-type, unresectable or metastatic melanoma. The drug is in Phase II trials for Metastatic Uveal Melanoma.
Pembrolizumab: Merck & Co Pembrolizumab (Keytruda) is an anti-programmed death receptor-1 (PD-1) therapy that enhances the immune system's ability to detect and combat tumor cells. Pembrolizumab (Keytruda) is a humanized monoclonal antibody that inhibits PD-1 interaction with PD-L1 and PD-L2, activating T lymphocytes that may impact both tumor and healthy cells. Merck has the broadest immuno-oncology clinical program, with over 1,600 trials on KEYTRUDA across various cancers and settings. The KEYTRUDA program explores its role in cancers and biomarkers predicting response, including multiple indicators. The drug is in Phase II trials for Metastatic Uveal Melanoma.
The Metastatic Uveal Melanoma Pipeline Report Provides Insights into
The report furnishes comprehensive details on organizations advancing therapies for Metastatic Uveal Melanoma, including the total treatments each company is developing.
It examines various therapeutic candidates categorized into initial, intermediate, and advanced development stages for Metastatic Uveal Melanoma management.
Metastatic Uveal Melanoma Companies are engaged in precision therapeutics with ongoing and paused (inactive or halted) initiatives.
Metastatic Uveal Melanoma Drugs in progress, sorted by development phase, delivery route, target receptor, standalone or combined therapy, unique action mechanisms, and molecular category.
Comprehensive review of partnerships (corporate alliances and academic ties), licensing deals, and funding information to drive future growth in the Metastatic Uveal Melanoma market.
Explore innovative treatments and clinical trials in the Metastatic Uveal Melanoma Pipeline. Obtain DelveInsight's detailed report today! @ New Metastatic Uveal Melanoma Drugs
Metastatic Uveal Melanoma Companies Bristol-Myers Squibb, Merck & Co, Verastem Oncology, AstraZeneca, IDEAYA Biosciences, BioMed Valley Discoveries, Miltenyi Biomedicine GmbH, Vanquish Oncology, Hoffmann-La Roche, Linnaeus Therapeutics, and others.
Metastatic Uveal Melanoma pipeline report assesses the therapeutic potential of pipeline drugs by Route of Administration. Products are grouped under different ROAs, including
Oral
Parenteral
Intravenous
Subcutaneous
Topical
Metastatic Uveal Melanoma Products have been categorized under various Molecule types such as
Monoclonal Antibody
Peptides
Polymer
Small molecule
Gene therapy
Learn about emerging Metastatic Uveal Melanoma drugs, pipeline advancements, and key companies with DelveInsight's expert analysis @ Metastatic Uveal Melanoma Market Drivers and Barriers
Scope of the Metastatic Uveal Melanoma Pipeline Report
Coverage- Global
Metastatic Uveal Melanoma Companies- Bristol-Myers Squibb, Merck & Co, Verastem Oncology, AstraZeneca, IDEAYA Biosciences, BioMed Valley Discoveries, Miltenyi Biomedicine GmbH, Vanquish Oncology, Hoffmann-La Roche, Linnaeus Therapeutics, and others.
Metastatic Uveal Melanoma Pipeline Therapies- DYP688, Nivolumab, Relatlimab, ZIV-Aflibercept, Cemiplimab, IDE196, Crizotinib, Pembrolizumab, Binimetinib, Dacarbazine, and others.
Metastatic Uveal Melanoma Therapeutic Assessment by Product Type: Mono, Combination, Mono/Combination
Metastatic Uveal Melanoma Therapeutic Assessment by Clinical Stages: Discovery, Pre-clinical, Phase I, Phase II, Phase III
Download DelveInsight's comprehensive Metastatic Uveal Melanoma Pipeline report now! @ Metastatic Uveal Melanoma Companies, Key Products and Unmet Needs
Table of Contents
Introduction
Executive Summary
Metastatic Uveal Melanoma: Overview
Pipeline Therapeutics
Therapeutic Assessment
Metastatic Uveal Melanoma - DelveInsight's Analytical Perspective
Mid Stage Products (Phase II)
Nivolumab: Bristol-Myers Squibb
Drug profiles in the detailed report.....
Early Stage Products (Phase I)
Drug Name: Company Name
Drug profiles in the detailed report.....
Early Stage Products (Preclinical)
Drug Name: Company Name
Drug profiles in the detailed report.....
Metastatic Uveal Melanoma- Future Perspectives and Conclusion
Metastatic Uveal Melanoma Analyst Views
Metastatic Uveal Melanoma Key Companies
Appendix
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