Publication

[120] "Functional Expression of Human Pyruvate Carboxylase for Reduced Lactic Acid Formation of Chinese Hamster Ovary Cells (DG44)", S. H. Kim and G. M. Lee, Appl. Biotechnol. Microbiol. 76: 659-665 (2007). 

[119] "Expression and Purification of the Recombinant Human Angiopoietin-1 in Chinses Hamster Ovary Cells", S. J. Hwang, H. J. Kim, G. Y. Koh, and G. M. Lee, In Vitro Cell Dev. Biol. Anim. 43: 162-167 (2007). 

[118] "Effect of Doxycycline-Regulated PDI Expression on Specific Productivity of Recombinant CHO Cells: Thrombopoietin and Antibody", C. Mohan, S. H. Park, J. Y. Chung, and G. M. Lee, Biotechnol. Bioeng. 98: 611-615 (2007).

[117] "Correlation between Enhancing Effect of Sodium Butyrate on Specific Productivity and mRNA Transcription Level in Chinese Hamster Ovary Cells Producing Antibody", M. K. Jeon and G. M. Lee, J. Microb. Biotechnol. 17: 1036-1040 (2007). 

[116] "Differences in Optimal pH and Temperature for Cell Growth and Antibody Production between Two Chinese Ovary Clones Derived from the Same Parental Clone.", S. H. Kim and G. M. Lee, J. Microb. Biotechnol. 17: 712-720 (2007). 

[115] "Down-Regulation of Cold-Inducible Binding Protein does not Improve Hypothermic Growth of Chinese Hamster Ovary Cells Producing Erythropoietin.", J. K. Hong, S. K. Yoon and G. M. Lee, Metab. Eng. 9:208-216 (2007). 

[114] "Down-Regulation of Lactate Dehydrogenase-A by siRNAs for Reduced Lactic Acid Formation of Chinese Hamster Ovary Cells Producing Thrombopoietin ", S. H. Kim and G. M. Lee, Appl. Biotechnol. Microbiol. 74:152-159 (2007). 

[113] "A Simple Analysis System for the Estimation of Recombination Efficiency Using Fluorescence-Activated Cell Sorting", M. S. Kim, W. H. Kim, and G. M. Lee, J. Biotechnol. 127:373-384 (2007). 

[112] "High Productivity of t-PA in CHO Cells Using Hypoxia Response Elements", G. W. Bae, D. W. Jeong, H. J. Kim, G. M. Lee, H. W. Park, T. B. Choi, S. M. Kang, and I. H. Kim, J. Microb. Biotechnol. 16:695-703 (2006). 

[111] "Limitations to the Development of Humanized Antibody Producing Chinese Hamster Ovary Cells Using Glutamine Synthetase-Mediated Gene Amplification", S. C. Jun, M. S. Kim, H. J. Hong, and G. M. Lee, Biotechnol. Prog. 22:770-780 (2006). 

[110] "Artificial Transcription Factors Increase Production of Recombinant Antibodies in Chinese Hamster Ovary Cells", R. J. Kwon, S. K. Kim, S. J. Hwang, G. M. Lee, J. S. Kim and W. Seol, Biotechnol. Lett. 28:9-15 (2006). 

[109] "Biphasic Culture Strategy for Enhancing Volumetric Erythropoietin Productivity of Chinese Hamster Ovary Cells", S. K. Yoon, S. H. Kim, J. Y. Song and G. M. Lee, Enzyme Microbiol Technol, 39:362-365 (2006). 

[108] "Adaptation of Chinese Hamster Ovary Cells to Low Culture Temperature: Cell Growth and Recombinant Protein Production", S. K. Yoon, J. K. Hong, S. H. Choo, J. Y. Song, H. W. Park and G. M. Lee, J. Biotechnol. 122:463-472 (2006). 

[107] "Initial Genome and Proteome Analysis of Low Culture Temperature-Induced Expression in CHO Cells Producing Erythropoietin", J. Y. Baik, M. S. Lee, S. K. Yoon, S. R. An, S. K. Yoon, E. J. Joo, Y. H. Kim, H. W. Park, and G. M. Lee, Biotechnol. Bioeng. 93:361-371 (2006). 

[106] "Influence of Down-Regulation of Caspase-3 by siRNAs on Sodium-Butyrate-Induced Apoptotic Cell Death of Chinese Hamster Ovary Cells Producing Thrombopoietin", Y. H. Sung, S. J. Hwang and G. M. Lee, Metab. Eng.  7:457-466 (2005). 

[105] "Long-Term Sustained COMP-Ang1 Induces Long-Lasting Vascular Enlargement and Enhanced Blood Flow", C. H. Cho, K. E. Kim, J. Byun, H. S. Jang, D. K. Kim, P. Baluk, F. Baffert, G. M. Lee, N. Mochizuki, J. Kim and G. Y. Koh, Circ. Res. 97: 86-94 (2005). 

[104]  "Multiple Angiopoietin Recombinant Proteins Activate the Tie1 Receptor Tyrosine Kinase and Promotes Its Interaction with Tie2", P. Saharinen, K. Kerkela, N. Ekman, M. Marron, N. Brindle, G. M. Lee, H. Augustin, G. Y. Koh, K. Alitalo. J. Cell. Biol. 169:239-243 (2005). 

[103] "Oligomerization and Multimerization is Critical for Angiopoietin-1 to Bind and Phosphorylate Tie2", K. T. Kim, H. H. Choi, M. O. Steinmetz, B. Maco, R. A. Kammerer, S. Y. Ahn, H. Z. Kim, G. M. Lee, G. Y. Koh, J. Biol. Chem. 20:20126-20131 (2005). 

[102] "Selection Strategies for the Establishment of Recombinant CHO Cell line with Dihydrofolate Reductase-Mediated Gene Amplification", S. C. Jun, M. S. Kim, J. Y. Baik, S. O. Hwang, and G. M. Lee, Appl. Biotechnol. Microbiol. 69:162-169 (2005). 

[101] "Intracellular Responses of Antibody Producing H69K-NGD Transfectoma Subjected to Hyperosmotic Pressure", S. W. Bae and G. M. Lee, J. Microb. Biotechnol. 15: 579-586 (2005). 

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