Publication

[140] “A Proteomic Approach for Identifying Cellular Proteins Interacting with Erythropoietin in Recombinant Chinese Hamster Ovary Cells” J. Y. Kim, Y. G. Kim, J. Y. Baik, E. J. Joo, Y. H. Kim, and G. M. Lee Biotechnol. Prog. 26: 246-251 (2010). 

[139] “Effect of XIAP Overexpression on Sodium Butyrate-Induced Apoptosis in Recombinant Chinese Hamster Ovary Cells Producing Erythropoietin”, Y. G. Kim, J. Y. Kim, and G. M. Lee J. Biotechnol., 144: 299-303 (2009). 

[138] “Enhancement of Recombinant Antibody Production in HEK 293E Cells by WPRE”, K. S. Kim, M. S. Kim, J. H. Moon, M. S. Jeong, J. Kim, G. M. Lee, P. K. Myung, and H.J. Hong Biotechnol. Bioprocess Eng. 14: 633-638 (2009). 

[137] “Use of NaCl Prevents Aggregation of Recombinant COMP-Angiopoietin 1 in Chinese Hamster Ovary Cells”, H. K. Ju, S. J. Hwang, C. J. Jeon, G. M. Lee, and S. K. Yoon J. Biotechnol., 143: 145-150 (2009). 

[136] “Effect of Ca2+ and Mg2+ Concentration in Culture Medium on the Activation of Recombinant Factor IX Produced in Chinese Hamster Ovary Cells”, W. H. Kim, J. S. Kim, Y. Yoon, and G. M. Lee J. Biotechnol. 142: 275-278 (2009). 

[135] “Enhanced Interferon-β Production by CHO Cells through Elevated Osmolality and Reduced Culture Temperature”, Y. K. Han, T. Y. Koo, and G. M. Lee, Biotechnol. Prog. 25: 1440-1447 (2009). 

[134] “Development of Serum-Free Medium Supplemented with Hydrolysates for the Production of Therapeutic Antibodies in CHO Cell Cultures Using Design of Experiments”, S. H. Kim and G. M. Lee Appl. Biotechnol. Microbiol. 83: 639-48 (2009). 

[133] “Effect of Bcl-xL Overexpression on Apoptosis and Autophagy in Recombinant Chinese Hamster Ovary Cells under Nutrient-Deprived Condition”, Y. G. Kim, J. Y. Kim, and G. M. Lee Biotechnol. Bioeng. 103: 757-766 (2009). 

[132] “Effect of Akt Overexpression on Programmed Cell Death in Antibody Producing Chinese Hamster Ovary Cells”, S. O. Hwang and G. M. Lee J. Biotechnol. 139: 89-94 (2009). 

[131] “Effect of Bcl-xL Overexpression on Specific Erythropoietin Productivity of Recombinant Chinese Hamster Ovary Cells Grown at 33°C and 37°C”, Y. G. Kim and G. M. Lee, Biotechnol. Prog. 25: 252-256 (2009). 

[130] “Angiopoietin-2 Exocytosis Is Stimulated by Sphingosine-1-Phosphate in Human Blood and Lymphatic Endothelial Cells. C. Jang, Y. J. Koh, N. K. Lim, H. J. Kang, D. H. Kim, S. K. Park, G. M. Lee, C. J. Jeon, G. Y. Koh. Arterioscler. Thromb. Vasc. Biol. (2009). 

[129] “Calnexin Overexpression Sensitizes Recombinant CHO Cells to Apoptosis Induced by Sodium Butyrate Treatment”, C. Mohan and G. M. Lee, Cell Stress and Chaperones 14: 49-60 (2009). 

[128] “Characterization of Site-specific Recombination Mediated by Cre Recombinase during the Development of Erythropoietin Producing CHO Cell Lines”, M. S. Kim, W. H. Kim, and G. M. Lee, Biotechnol. Bioprocess Eng. 13: 418-423 (2008). 

[127] “High-Level Expression and Purification of a Designed Angiopoietin-1 Chimeric Protein, COMP-Ang1, Produced in Chinese Hamster Ovary Cells”, S. J. Hwang, S. H. Kim, H. Z. Kim, M. O. Steinmetz, G. Y. Koh, and G. M. Lee, Protein J. 27: 319-326 (2008). 

[126] “A Use of Flp-Mediated Cassette Exchange in the Development of a CHO Cell Line Stably Producing Erythropoietin”, M. S. Kim and G. M. Lee J. Micobiol. Biotechnol. 18: 1342-1351 (2008). 

[125] “Assessment of Cell Engineering Strategies for Improved Therapeutic Protein Production in CHO Cells”, C. Mohan, Y. G. Kim, J. Koo, and G. M. Lee Biotechnol. J. 3: 624-630 (2008). 

[124] “Autophagy and Apoptosis in Chinese Hamster Ovary Cell Culture”, S. O. Hwang and G. M. Lee Autophagy 4: 70-72 (2008). 

[123] "Limitations to the Comparative Proteomic Analysis of Thrombopoietin Producing Chinese Hamster Ovary Cells Treated with Sodium Butyrate", J. Y. Baik. E. J. Joo, Y. H. Kim, and G. M. Lee, J. Biotechnol. 133:461-468 (2008). 

[122] "Nutrient Deprivation Induces Autophagy as well as Apoptosis in Chinese Hamster Ovary Cell Culture", S. O. Hwang and G. M. Lee, Biotechnol. Bioeng. 99:678-685 (2008). 

[121] "Influence of Co-Down-Regulation of Caspase-3 and Caspase-7 by siRNAs on Sodium Butyrate-Induced Apoptotic Cell Death of Chinese Hamster Ovary Cells Producing Thrombopoietin ", Y. H. Sung, J. S. Lee, S. H. Park, and G. M. Lee, Metab. Eng. 9: 452-464 (2007). 

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