Chemical Pathology

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Makluman Penghantaran Borang Permohonan Ujian Blood Gas dan Lactate Secara Berasingan ke Makmal Integrasi dan Patologi Kimia. Mohon rujuk memo HQE.700-4/1/23(24) bertarikh 7 Mei 2025.
Makluman Perubahan Prosedur dan Peringatan Bagi Permohonan Ujian Biokimia di Makmal Integrasi dan Patologi Kimia. Mohon rujuk memo HQE.700-4/1/23 jld.2(25) bertarikh 3 Disember 2024.
Makluman Penawaran Ujian Rheumatoid Factor di Makmal Integrasi dan Patologi Kimia, Jabatan Patologi. Mohon rujuk memo HQE.700/4/1/23(26) bertarikh 4 Mac 2024.
Makluman Indikasi Ujian Urine Protein Electrophoresis dan Peringatan Cop Pakar Untuk Ujian Khas Biokimia. Mohon rujuk memo HQE.700-4/1/23(23) dan Surat Edaran HQE.700-4/1/23(24) bertarikh 4 Mac 2024.
Makluman Pengemaskinian Lab Turn Around Time (LTAT) Ujian Bukan Rutin Biokimia di Makmal Integrasi dan Patologi Kimia, Jabatan Patologi. Mohon rujuk memo HQE.700-4/1/23 JLD.2(63) bertarikh 19 Disember 2023.
Makluman Penawaran Ujian 24HR Urine Copper, Serum Copper dan Blood Lead di Jabatan Patologi Hospital Selayang. Mohon rujuk memo HQE.700-4/1/23 JLD.1(83) bertarikh 20 Disember 2023 dan Surat Edaran HS PAT/210/01-02 JLD 3 (102) bertarikh 15 Disember 2023.
Makluman Penawaran Ujian Salivary Cortisol di Jabatan Patologi, Hospital Pulau Pinang. Mohon rujuk memo HQE.700-4/1/23 JLD.2 (62) bertarikh 1 Disember 2023.
Makluman Penukaran Pengoperasian Analisa Ujian TDM Sirolimus di Jabatan Patologi Hospital Tunku Azizah. Mohon rujuk memo HQE.700-4/1/1 JLD.5(20) bertarikh 2 November 2023 dan Surat Edaran HWKKKL.100-6/2/72 (16) bertarikh 18 Oktober 2023.
Makluman Panduan Justifikasi Klinikal Ujian Endokrin Khas yang Ditawarkan oleh Jabatan Patologi Hospital Putrajaya. Mohon rujuk memo HQE.700-4/1/23 JLD.2(41) bertarikh 13 Oktober 2023 dan Surat Edaran Bil. (91) dlm HPJ 700/14/1 Jld.57 bertarikh 9 Oktober 2023.
Makluman Pindaan Bagi Ujian - Ujian Biokimia, Immunoassay dan Immunochemistry di Makmal Integrasi dan Patologi Kimia. Mohon rujuk memo HQE.700-4/1/23 JLD.2(14) bertarikh 21 Ogos 2023.

General information:

Chemical pathology services are divided into:

A. Integrated Laboratory that offers:

a. Routine Biochemistry

b. Endocrine & Metabolic Medicine

c. Tumor Markers

d. Protein

e. Therapeutic Drug Monitoring (TDM) & Clinical Toxicology

B. Chemical Pathology Unit that offers Protein Electrophoresis test and Referral section.

C. Makmal Pengesanan Dadah that offers screening and confirmatory for Drug of Abuse (DOA).

Integrated Laboratory located at the second floor, Twin Tower building. Extension 8241/8242.

Chemical Pathology Unit located at the first floor, Complex D (Pathology Department). Extension 7280/7136.

Makmal Pengesanan Dadah located at the second floor, Twin Tower building next to Integrated Laboratory and Chemical Pathology unit. Extension 8239.

Tests that are offered as 24 hours service are:
- 1. 1. Blood gases (Arterial blood gases/venous blood gases)
    2. Albumin
    3. Amylase
    4. Ammonia
    5. Alanine Transaminase (ALT)
    6. Aspartate Transaminase (AST)
    7. Alkaline Phosphatase (ALP)
    8. Bilirubin (Total and Direct)
    9. BUSE (Sodium, Potassium, Chloride, Urea)
    10. Calcium
    11. Creatine Kinase (CK)
    12. Creatinine
    13. C-Reactive Protein (CRP)
    14. CSF Biochemistry (Glucose and Protein)
    15. Fasting Lipid Profile
    16. Gamma-Glutamyl Transferase (GGT)
    17. Glucose
    18. Ketone (Beta-Hydroxybutyrate)
    19. Lactate
    20. Lactate Dehydrogenase (LDH)
    21. Magnesium
    22. Phosphate, inorganic
    23. Troponin I (High Sensitivity)
    24. Total Protein
    25. Uric Acid
    26. Urine Fluid Examination and Microscopic Examination (UFEME)
    27. Urine Paraquat
    28. Urine Pregnancy Test
    29. Suspected Therapeutic Drug Toxicity (except Tacrolimus and Cyclosporin) and clinical Toxicology (Acetaminophen and Salicylate).
    30. Total Beta human Chorionic Gonadotrophin (B-hCG)

Tests that are offered during office hours are:

- A. Specialised Biochemistry

Thyroid Function Test (TSH, fT4, fT3)
Cortisol
Intact Parathyroid Hormone (iPTH)
Estradiol, Progesterone, FSH, LH, Prolactin, Total Testosterone
Tumor Markers (AFP, CA-125, CA 19-9, CEA, PSA, CA 15-3)
Hematological Markers (Iron studies, Vitamin B12, Folate, Ferritin)
Serum Immunoglobulin level (IgG/A/M), Complement C3, C4, Procalcitonin, Rheumatoid Factor
Serum dan Urine Protein Electrophoresis.
Serum dan Urine Osmolality
Creatinine Clearance
Urine Albumin:Creatinine Ratio (UACR)
Urine Calcium:Creatinine Ratio (UCCR)
Urine Protein:Creatinine Ratio (UPCR)
Dexamethasone Suppresion Test
(ACTH) Synacthen Stimulation Test
Fluid for Biochemistry (Albumin, Protein & LDH)

B. Hemoglobin A1c (HbA1c)

C. Therapeutic Drug Monitoring: 'Outside office hours' testing MUST be requested through TDM pharmacist.
1. 1. Amikacin
  2. Gentamicin
  3. Vancomycin
  4. Sodium Valproate
  5. Phenytoin
  6. Carbamazepine
  7. Phenobarbitone
  8. Digoxin
  9. Theophylline (Aminophylline)
  10. Methotrexate
  11. Lithium
  12. Tacrolimus
  13. Cyclosporine

D. Drug of Abuse Testing
1. 1. Amphetamine Type Stimulants (screening)
  2. Amphetamine / Methamphetamine / MDA [3,4-Methylenedioxyamphetamine] / MDMA [3,4-Methylenedioxymethamphetamine] / Phentermine / Ephedrine (confirmation)
  3. Opiate (screening)
  4. Morphine / Codeine (confirmation)
  5. Cannabis (screening)
  6. THC [11-nor-delta-9-tetrahydrocannabinol-9-carboxylic acid] (confirmation)
  7. Ketamine (screening)
  8. Ketamine / Norketamine (confirmation)

For Drug of Abuse testing:

We are only reporting detected or not detected in clinical request.
Results are reported based on the cut-off for medicolegal purposes.
Specimen MUST BE accompanied by Borang UPD 1 (pindaan 2020)
Methodology: Immunoassay for screening; Thin Layer Chromatography (TLC) for Morphine/Codeine and THC.
Methodology: Gas Chromatography Mass Spectrometry (GCMS) for amphetamine group and ketamine confirmation.

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