Madison Seminary in Madison, Ohio, was established in 1845 and opened in 1847 as a private school offering secondary and college preparatory education. As enrollment grew, a large brick building was added in 1859 to accommodate its expanding student population. The school operated until 1881, when changing educational opportunities and declining enrollment led to its closure. In 1891, the Ohio Women's Relief Corps purchased the property and transformed it into the Madison Home, providing housing and assistance for widows, mothers, and other female relatives of Union Civil War veterans, as well as former Army nurses. In 1904, the state of Ohio took ownership and continued operating the home for veterans' families for several decades. In 1962, the property became Opportunity Village, a state facility that provided services and vocational rehabilitation for women with disabilities. Opportunity Village closed in 1975, ending the building's long history of institutional use. The property later served as Madison Township offices before eventually becoming vacant and falling into disrepair. Added to the National Register of Historic Places in 1979, the building was eventually purchased by private owners who began efforts to preserve and restore it. Today, Madison Seminary is remembered for its many chapters of Ohio history and has also become well known as a destination for paranormal investigations.