MAIN RESEARCH AREAS
GENETICS OF HAIR SHAPE
Variants of hair shape are of high priority for investigation as most of the hair variants are positively selected. However, it is not clear if hair shape itself was the target of selection or it some other trait which is under selection. We have diversity of hair shape existing in the world - kinky (very curly), curly, wavy and straight hair between and across populations. However, due to complex nature of hair, very less genes/variants have been identified. Therefore, it is interesting to study the genes and molecular mechanism of hair shape as well as evolution of hair shape.
GENETICS OF HIGH ALTITUDE ADAPTATION
Our research focuses on high altitude biology states about the adaptive qualities of individuals residing at the utmost higher elevation for regions such as the Andes, the Himalayas, and the Ethiopian highlands and how they developed unique ways to cope with low oxygen levels, known as hypoxia along with other physiological parameters. Studying how individuals are distributed at different altitudes provides valuable insights. Unlike changes in latitude, altitude changes influence factors like temperature, humidity, and barometric pressure. These factors affect metabolic rates and other biological processes. In essence, high-altitude environments offer a unique context to understand how living organisms adapt, both in the short term and over generations, to the challenges posed by low oxygen levels and changing environmental conditions.
GENETICS OF FINGERPRINT PATTERNING
Dermatoglyphics are unique patterns of ridges and furrows on the skin's surface, particularly on the palms, fingers, soles, and toes.These patterns, commonly known as fingerprints, start to develop around the 10th week of gestation, originating from specialized areas called volar pads.By the 14th week of gestation, primary ridges define the future fingerprint pattern at the epidermal-dermal junction.Fingerprint patterns are categorized into three main types: arches, loops, and whorls.Arches have ridges that enter from one side and exit from the other without completing a circuit.Loops are the most common pattern, with ridges entering from one side, looping, and exiting from the same side.Whorls have circular or spiral patterns and at least one ridge that completes a circuit.