口腔顏面疼痛與神經科學

NYCU Orofacial Pain and Neuroscience (2023 New)

NYCU Orofacial Pain and Neuroscience is a newly updated course for undergraduate and postgraduate students. This is the first course of orofacial pain and neuroscience in Taiwan that follows the curriculum outline of the International Association for the Study of Pain (IASP) and the American Academy of Orofacial Pain (AAOP).

本課程2023年重新改版，為國內首次銜接國際疼痛研究學會課綱，美國口腔疼痛學會課綱，與世界知名牙醫學院課程接軌的口腔顏面疼痛與神經科學課程。歡迎大學部與研究所同學選修。

Welcome to our class ‘Orofacial Pain and Neuroscience’! I am Chia-Shu Lin, now a professor of the Department of Dentistry and adjunct professor of the Institute of Brain Science. I am also one of the very few people who specialize in both dentistry and neuroscience (focusing on brain imaging) in the world. This course, previously known as ‘Orofacial Pain’, has been taught in the Department of Dentistry for seven years. From this year, the course will be largely revised for both students with a dental background and students ‘without any dental background’. The course offers an introduction to the neurophysiological mechanisms of oral functions, dysfunctions, and principles of clinical management. The course will be modularized into three parts:

Module I - Understanding the human stomatognathic system

In the first five lessons, we will focus on the sensory and motor functions of the oral system, including oral somatosensation, pain, mastication, and swallowing.

Module II – Assessment and classification of dysfunctions

From Lesson 6 to Lesson 10, we will focus on how to assess mastication, swallowing and pain. We will also focus on the clinical classification of chronic orofacial pain.

Module III – From patient experience to behavior

In the last five lessons, we will focus on patients’ emotional experience and decision-making behavior and individual variations in their experience, including the principles of managing pain and dysfunctions of older patients.

課程簡介(中文)

各位對選修「口腔顏面疼痛與神經科學」感興趣的同學您好，我是嘉澍老師，現任牙醫系專任教授與腦科學研究所合聘教授，也是世界上極少數的兼具牙醫師與腦科學(神經造影)專長的人類。這門課原過去在陽明牙醫系是已經有七年歷史的「口腔顏面疼痛」，比較偏向臨床議題。而今年開始，本課程將重新規劃教學方向，希望不僅提供牙醫師，也包含「非口腔專業領域」的同學，一個入門的機會，了解與口腔功能相關的生理機制，以及相關的病變與臨床處理原則。故今年的課程將聚焦在以下目標，區分為三個大的模組：

從神經科學了解口顎系統如何運作：本課程的模組一(前五次上課)將聚焦在口腔的感覺與運動功能，包括口腔內的觸覺、疼痛、吞嚥，與咀嚼等功能。
口腔功能檢測與疼痛的分類：本課程的模組二(第六~第十次上課)將聚焦在如何評估咀嚼吞嚥與口腔顏面疼痛，並介紹臨床上對口腔顏面疼痛的分類。重點在於針對這些測量技術，引導同學做跨領域的思考。
從牙齒到全人照顧：本課程的模組三(最後五次上課)將聚焦在「病人」的經驗與行為，包括病患的情緒經驗，醫療決策行為，以及面對年長者或認知功能障礙病患，各種處理口腔功能障礙與疼痛的基本原則。

This is an introductory course. Students do not need to complete other courses for entering this course. Students are welcome if they are:

Students with a background in the dental or oral health discipline, who want to further understand orofacial pain and functions.
Students with a background in clinical disciplines other than dentistry (e.g. medicine or nursing), who want to further understand orofacial pain and functions.
Students with a non-clinical background (e.g., EE, IE, biomechanics, etc.), who want to understand the mechanisms of oral functions and the current challenges in treating orofacial pain and dysfunctions. Students are welcome to bridge their knowledge in science and technology for solving clinical problems.

All faculties from the Chiao-Tong campus are welcome to participate us via the distant virtual classroom.

選修須知(中文)

本課程為一概論性質課程，無須事先修過其他課程。

凡有下列三種興趣的同學，皆歡迎選修：

牙醫或口腔照顧相關科系背景的同學，希望進一步了解口腔顏面疼痛與功能。
非牙醫或口腔照顧的其他醫護背景同學(例如醫學系或護理系)，希望了解口腔顏面疼痛與功能。
非臨床醫護背景的同學 – 特別是理工電資背景的同學 – 希望了解口腔功能運作的基本原則，並認識當前口腔醫學臨床治療的挑戰，進一步激發跨領域的思考，將科學與工程方面的知識應用於解決口腔健康的臨床問題。

本課程竭誠歡迎交大校區師長遠距收看並惠賜意見。

Module I： The Stomatognathic System

Lesson 1 Introduction to Orofacial Pain and Neuroscience

口腔的疼痛與神經科學議題簡介

• IASP Terminology https://www.iasp-pain.org/resources/terminology

Lesson 2 Oral Somatosensation, Gustation and Bon Appétit

口腔的感覺、味覺與「美食感」

Oral somatosensory processing | Oral somatosensation | Oral somatoperception | Gustation | The feeling of Bon Appétit

• Trulsson (2006) Sensory-motor function of human periodontal mechanoreceptors, J Oral Rehab

• Breslin (2013) An Evolutionary Perspective on Food and Human Taste, Current Biology

Lesson 3 Neural Mechanisms of Mastication and Swallowing

咀嚼與吞嚥的神經機制

• Woda et al. (2011) Mastication in humans: finding a rationale, J Oral Rehab

Lesson 4 Peripheral Mechanisms about Pain Processing

痛覺傳導的周邊神經機制

Dentin hypersensitivity | From oral receptors to CN.V | Gate control theory | Heterotopic pain | Clinical implications

• Shiau (2012) Dentin hypersensitivity, J Evid Based Dent Pract

• Mendell (2014) Constructing and deconstructing the gate theory of pain, Pain

Lesson 5 Brain Mechanisms about Pain Processing

疼痛經驗的腦神經機制

Basic concepts | How does our brain work? | Neuroimaging | Pain and the brain | Cognitive-affective factors

• Davis et al. (2020) Discovery and validation of biomarkers to aid the development of safe and effective pain therapeutics: challenges and opportunities, Nat Rev Neurol

• Wiech (2016) Deconstructing the sensation of pain: The influence of cognitive processes on pain perception, Science

Module I Discussion

Module II： Assessment and Classification

Lesson 6 Assessment of Masticatory and Swallowing Performance

咀嚼與吞嚥功能的評估

Basic concepts | Masticatory performance | Associated factors | Clinical applications | Swallowing performance

• van der Bilt (2011) Assessment of mastication with implications for oral rehabilitation: a review. J Oral Rehabil

• Gonçalves et al. (2021) Consensus on the terminologies and methodologies for masticatory assessment, J Oral Rehabil

Lesson 7 Assessment of pain: taking history and using pain scales

疼痛經驗的評估：問診與使用量尺

• Dworkin et al. (2008) Interpreting the clinical importance of treatment outcomes in chronic pain clinical trials: IMMPACT recommendations, J Pain

Lesson 8 Neural Mechanisms of Masticatory and Swallowing Dysfunction

咀嚼與吞嚥功能障礙的神經機制

• Sessle (2019) Can you be too old for oral implants? An update on ageing and plasticity in the oro‐facial sensorimotor system, J Oral Rehabil

• Lin (2020) Functional Adaptation of Oromotor Functions and Aging: A Focused Review of the Evidence From Brain Neuroimaging Research, Frontiers in Aging Neuroscience

Lesson 9 Non-odontogenic Orofacial Pain

口腔顏面非齒源性疼痛

• Schiffman et al. (2014) Diagnostic Criteria for Temporomandibular Disorders (DC/TMD) for Clinical and Research Applications: Recommendations of the International RDC/TMD Consortium Network and Orofacial Pain Special Interest Group, J Orofac Pain

• Renton (2020) Tooth-Related Pain or Not? Headache

Lesson 10 Neuropathic Orofacial Pain and Altered Sensation

口腔顏面神經性疼痛與感覺異常

• Woolf (2011) Central sensitization: Implications for the diagnosis and treatment of pain, Pain

• Benoliel et al. (2014) Pain Painful Traumatic Trigeminal Neuropathy, PAIN Clin. Updat

Module II Discussion

Module III： Patient Experience and Behavior

Lesson 11 Pain-related Negative Emotions

疼痛相關之負面情緒與處理

• Lin et al. (2016) Association between Anxiety and Pain in Dental Treatment, J Dent Res

Lesson 12 Principles of Pharmacological Management on Orofacial Pain

藥物疼痛控制的原則與方法

Basic concepts of pharmacological management | Non-opioid analgesics | Local anesthesia | Pharmacological management of the elderly | Practical issues

• ADA (2022) Oral Analgesics for Acute Dental Pain https://www.ada.org/resources/research/science-and-research-institute/oral-health-topics/oral-analgesics-for-acute-dental-pain

Lesson 13 Aging and Orofacial Pain in Elderly People

老化與年長者口腔顏面疼痛問題

• ADA (2019) Aging and Dental Health https://www.ada.org/en/member-center/oral-health-topics/aging-and-dental-health

Lesson 14 Management of Masticatory and Swallowing Dysfunction of Older People

年長者咀嚼與吞嚥障礙之處理

Peripheral approaches of management | Brain-oriented approaches of management | An integrative view

• Shu et al. (2022) A Systematic Review and Meta-analysis of the Effect of Oral Exercises on Masticatory Function, J Dent Res

Lesson 15 Communication and Medical Decision-making

有關口腔顏面疼痛之醫病關係議題

Shared decision-making | Utility and decision-making | Communication on ’risk’ | Clinical implications

• NHS Shared decision-making https://www.england.nhs.uk/personalisedcare/shared-decision-making

• Taiwan Patient Safety Net (2022) https://www.patientsafety.mohw.gov.tw/xmdoc/cont?xsmsid=0M097527397785648684

Module III Discussion

Lesson 16： End-of-term discussion

作業與討論內容期末回顧

Supplementary Classes

Oral functions and the brain - A perspective from neuroimaging and the brain-stomatognathic axis (2018 International Association of Dental Research)

如果牙醫師不能止痛，那還有什麼用？(2018陽明心哲所秋季系列講座疼痛與受苦主題)

Google Sites

Report abuse