Phylogenetic observations

Main Observation (not written to the finest detail):

1. Species from different genera and/or sub-genera are branched beside one another. There is no distinguishable grouping of all members of the same genus and species. In other words, this tree is "scattered."

• Species from different genera branched close together:

1. Avian coronavirus (HQ853289), a Gammacoronavirus, and Murine coronavirus (NC_012936), a Betacoronavirus, are branched right next to each other, indicating a close phylogenetic and/or evolutionary relationship.

• Species from different genera branched closer together than the same species themselves:

1. Avian coronavirus (KR605488), a Gammacoronavirus, and Pipistrellus bat coronavirus HKU5 (NC_009020), a Betacoronavirus, are branches right next to each other, indicating a close phylogenetic and/or evolutionary relationship. In fact the Pipistrellus bat coronavirus HKU5 is closer to the Avian coronavirus than it is to another Pipistrellus bat coronavirus HKU5 (KJ473820).

2. Wigeon coronavirus HKU20 (NC_016995), a Deltacoronavirus, is branched closer to Avian coronavirus (HQ853289), a Gammacoronavirus, and Murine coronavirus (NC_012936), a Betacoronavirus, than it is to other Deltacoronaviruses.

• Same species are scattered or "split apart":

1. Severe acute respiratory syndrome-related coronavirus (KY352407) in the Rhinolophus, is closer to the Middle East respiratory syndrome-related coronavirus (MK796425) in the human, and the Middle East respiratory syndrome-related coronavirus (MN507638) in the Lama glama, than it is to other SARS-related viruses, including the SARS virus (FJ588686) in the Rhinolophus sinicus, the SARS virus (GU553363) in the human, and the SARS virus (GU553365) in the Chlorocebus aethiops.

• Interestingly, all other species EXCEPT the Severe acute respiratory syndrome-related coronavirus 2, a novel Betacoronavirus, are "split apart":

1. All Severe acute respiratory syndrome-related coronavirus 2 (MT457401, MT811522, NC_045512, MT709104, MT270814, MT365033) sequences are grouped together.

*NOTE: These observations are solely based on the phylogenetic tree, created with NCBI Virus' phylogenetic tree builder. However, they do not make complete scientific sense. Therefore, there could be a flaw in sequence alignment. Scientific investigations to evaluate the accuracy of the phylogenetic tree have not been conducted.