研究業績/Publications
大門高明
2016.4 〜
学会発表リストはこちら。
原著論文：
69. Zefu Wan, Takuya Tsubota, Keiro Uchino, Hideki Sezutsu, Takaaki Daimon* (2024) MMEJ-mediated precise gene knock-in into the Fibroin-L locus of the silkworm, Bombyx mori. Journal of Insect Biotechnology and Sericology (in press).
68. Naoki Matsuda*, Momoyo Takahashi, Yu Shirai, Norihide Hinomoto, Takaaki Daimon* (2024) Direct parental CRISPR gene editing in the predatory bug Orius strigicollis, a biocontrol agent against small arthropods. Pest Management Science. (in press)
67. Tsuyoshi Maruoka, Yu Shirai, Takaaki Daimon, Rei Fujii, Masako Dannoura, Irmgard Seidl-Adams, Naoki Mori, Naoko Yoshinaga (2024) Knock-out of ACY-1 like gene in Spodoptera litura supports the notion that FACs improve nitrogen metabolism. Journal of Chemical Ecology. (in press)
66. Yu Shirai, Momoyo Takahashi, Manabu Ote, Hirotaka Kanuka, Takaaki Daimon* (2023) DIPA-CRISPR gene editing in the yellow fever mosquito Aedes aegypti (Diptera: Culicidae). Applied Entomology and Zoology 58, 273-278.
65. Yu Shirai, Hajime Ono, Takaaki Daimon* (2023) Redundant actions of neuropeptides encoded by the dh-pban gene for larval color pattern formation in the oriental armyworm Mythimna separata. Insect Biochemistry and Molecular Biology (in press).
64. Kei Inada, Toshinori Minemura, Takahiro Ohde, Takaaki Daimon* (2023) Mating behaviors and multiple mating in the firebrat, Thermobia domestica (Zygentoma: Lepismatidae). Applied Entomology and Zoology 58, 297-302.
63. A. Fernandez-Nicolas, G. Machaj, A. Ventos-Alfonso, V. Pagone, T. Minemura, T. Ohde, T. Daimon, Guillem Ylla, Xavier Belles (2023) Reduction of embryonic E93 expression as a hypothetical driver of the evolution of insect metamorphosis. Proc Natl Acad Sci USA 120(7): e2216640120. DOI: 10.1073/pnas.2216640120
成虫化誘導遺伝子E93の発現タイミングのシフトが昆虫の変態の進化をもたらした、という仮説を提案しました。今後、この仮説が実験的に検証されていく（いきたい）と思います。
スペインのIBE (Institut de Biologia Evolutiva)からのプレスリリースはこちら。
62. H. Kato, K. Nemoto, M. Shimizu, A, Abe, S. Asai, N. Ishihama, S. Matsuoka, T. Daimon, M. Ojika, K. Kawakita, K. Onai, K. Shirasu, M. Yoshida, M. Ishiura, D. Takemoto, Y. Takano, R. Terauchi. Recognition of pathogen-derived sphingolipids in Arabidopsis. Science 376, 857–860. DOI:10.1126/science.abn0650
寺内先生、加藤先生のお仕事をお手伝いさせていただきました。RDA2 (lectin receptor-like kinase)の細胞外ドメインをバキュロで発現/生産するパートを担当しました。学生時代に教えていただいたカイコ/BmNPVの実験系が思わぬところで活躍してくれました。やはり、カイコ虫体をつかえるところがBmNPVのナイスなところだと思います。
61. Yu Shirai, Maria-Dolors Piulachs, Xavier Belles, Takaaki Daimon* (2022) DIPA-CRISPR is a simple and accessible method for insect gene editing. Cell Reports Methods 2, 100215. https://doi.org/10.1016/j.crmeth.2022.100215
成虫注射による簡便な昆虫ゲノム編集法（DIPA-CRISPR）の論文が、Cell Reports Methods誌に掲載されました。
サイエンスイラストレータの大内田美沙紀さんに書いていただいたイラスト（(C) Misaki Ouchida）が、カバーイメージに採択されました。学生風の２人が、色々な昆虫のペーパークラフトを壁にピンで留めている様子（注射のイメージ）が表現されています。ちょうど、ジャーナルが１周年を迎えたということで、1st anniversaryを示すマークが左下についています。
研究成果についての報道も多数していただきました。ありがとうございました。
2024.03.18追記
本成果を主要業績として、白井雄さんが令和５年度京都大学総長賞を受賞しました。
表彰式の様子はこちら（京大HP）
60. Tomohiro Inui, Hideki Sezutsu, Takaaki Daimon* (2022) MicroRNA let-7 is required for hormonal regulation of metamorphosis in the silkworm, Bombyx mori. Insect Biochemistry and Molecular Biology 145, 103784. https://doi.org/10.1016/j.ibmb.2022.103784
59. Satoshi Homma, Akihisa Murata, Masato Ikegami, Masakazu Kobayashi, Maki Yamazaki, Kento Ikeda, Takaaki Daimon, Hideharu Numata, Akira Mizoguchi, Kunihiro Shiomi (2022) Circadian clock genes regulate temperature-dependent diapause induction in silkworm Bombyx mori. Frontiers in Physiology 13:863380.
58. H. Kato, K. Nemoto, M. Shimizu, A Abe, S. Asai, N. Ishihama, T. Daimon, M. Ojika, K. Kawakita, K. Onai, K. Shirasu, M. Ishiura, D. Takemoto, Y. Takano, R. Terauchi. Pathogen-derived 9-methyl sphingoid base is perceived by a lectin receptor kinase in Arabidopsis. bioRxiv 2021.10.18.464766; doi: https://doi.org/10.1101/2021.10.18.464766
57. Yusuke Shiota, Tekeshi Sakurai, Noriyasu Ando, Stephen S Haupt, Hidefumi Mitsuno, Takaaki Daimon, Ryohei Kanzaki (2021) Pheromone binding protein is involved in temporal olfactory resolution in the silkworm.iScience 24, 103334.
56. Kento Ikeda, Takaaki Daimon, Kunihiro Shiomi, Hiroko Udaka, Hideharu Numata (2021) Involvement of the clock gene period in the photoperiodism of the silkmoth Bombyx mori. Zoological Science 38, 523–530.
カイコ成虫の写真がZoological Science誌の表紙に採択されました。
下の写真の別バージョンです。
55. Tsuguru Fujii, Takashi Kiuchi, Takaaki Daimon, Katsuhiko Ito, Susumu Katsuma, Toru Shimada, Kimiko Yamamoto, Yutaka Banno (2021) Development of interspecific semiconsomic strains between the domesticated silkworm, Bombyx mori, and the wild silkworm, Bombyx mandarina. Journal of Insect Biotechnology and Sericology 90, 33-40.
54. Yu Shirai, Takahiro Ohde, Takaaki Daimon* (2021) Functional conservation and diversification of yellow-y in lepidopteran insects. Insect Biochemistry and Molecular Biology 128, 103515. (*, corresponding author)
53. Takaaki Daimon*, Takashi Koyama, Gaku Yamamoto, Hideki Sezutsu, Christen K Mirth, Tetsuro Shinoda (2021) The number of larval molts is controlled by Hox in caterpillars. Current Biology 31, 884-891. (*, corresponding author)
カイコ成虫の写真がCurrent Biology誌の表紙に採択されました！
複眼でDsRed2（赤色蛍光タンパク質）を発現する組換えカイコ（雌）です。
2021年2月2日 京都新聞夕刊の１面に記事を掲載していただきました。
記事の中のイモ画像（と呼ぶらしい）は、４眠を終えた直後のカイコ幼虫です。学生実験用に飼っていた実用系統「錦秋鐘和（きんしゅうしょうわ）」です（上田蚕種）。
この画像と上に載せた成虫の画像を、cover imageの候補として編集部に送りましたが、成虫の方が採用されました。このイモ画像は雑誌の表紙にはなりませんでしたが、新聞の１面を飾ってくれました。
（京都新聞社の使用許諾を得て転載）
52. Kakeru Yokoi, Yuki Nakamura, Akiya Jouraku, Gaku Akiduki, Miwa Uchibori-Asano, Seigo Kuwazaki, Yoshitaka Suetsugu, Takaaki Daimon, Kimiko Yamamoto, Hiroaki Noda, Sachiyo Sanada-Morimura, Masaya Matsumura, Le Quoc Cuong, Ho Van Chien, Gerardo F Estoy, Jr, and Tetsuro Shinoda (2021) Genome-wide assessment and development of molecular diagnostic methods for imidacloprid-resistance in the brown planthopper, Nilaparvata lugens (Hemiptera; Delphacidae). Pest Management Science 77, 1786-1795.
51. Takahiro Ohde, Toshinori Minemura, Eiichi Hirose, Takaaki Daimon (2020) Egg Microinjection and Efficient Mating for Genome Editing in the Firebrat Thermobia domestica. Journal of Visualized Experiments 164, e61885. DOI:10.3791/61885.
50. Yuri Homma, Kouhei Toga, Takaaki Daimon, Tetsuro Shinoda, Toru Togawa (2020) A mitochondrial phosphatase PTPMT1 is essential for the early development of silkworm, Bombyx mori. Biochemical and Biophysical Research Communications 530, 713-718.
49. Yu Shirai, Takaaki Daimon* (2020) Mutations in cardinal are responsible for the red-1 and peach eye color mutants of the red flour beetle Tribolium castaneum. Biochemical and Biophysical Research Communications 529, 372-378. (*, corresponding author)
48. Hiroki Sakai, Hiroyuki Oshima, Kodai Yuri, Hiroki Gotoh, Takaaki Daimon, Toshinobu Yaginuma, Ken Sahara, and Teruyuki Niimi (2019) Dimorphic sperm formation by Sex-lethal. Proc Natl Acad Sci USA 116(21), 10412-10417.
カイコ成虫の写真（酒井さん・基生研）がPNAS誌の表紙に採択されました！
47. Kento Ikeda, Takaaki Daimon, Hideki Sezutsu, Hiroko Udaka, Hideharu Numata (2019) Involvement of the clock gene period in the circadian rhythm of the silkworm Bombyx mori. Journal of Biological Rhythms DOI: 10.1177/0748730419841185
46. Miwa Uchibori-Asano, Akiya Jouraku, Toru Uchiyama, Kakeru Yokoi, Gaku Akiduki, Yoshitaka Suetsugu, Tetsuya Kobayashi, Akihito Ozawa, Saki Minami, Chiharu Ishizuka, Yoshiaki Nakagawa, Takaaki Daimon, Tetsuro Shinoda (2019) Genome-wide Identification of Tebufenozide Resistant Genes in the smaller tea tortrix, Adoxophyes honmai (Lepidoptera: Tortricidae). Scientific Reports 9, 4203.
45. Yusuke Shiota, Takeshi Sakurai, Takaaki Daimon, Hidefumi Mitsuno, Takeshi Fujii, Shigeru Matsuyama, Hideki Sezutsu, Yukio Ishikawa, Ryohei Kanzaki (2018) In vivo functional characterization of pheromone binding protein-1 in the silkmoth, Bombyx mori. Scientific Reports 8, 13529.
44. Masashi Tanaka, Takaaki Daimon* (2018) Tissue localization of aggregation pheromones in the American cockroach, Periplaneta americana (Blattodea: Blattidae). Applied Entomology and Zoology 53, 447-452. (*, corresponding author)
43. Masashi Tanaka, Takaaki Daimon* (2019) First molecular genetic evidence for automictic parthenogenesis in cockroaches. Insect Science 26: 649-655. (*, corresponding author)
42. Miwa Uchibori-Asano, Takumi Kayukawa, Hideki Sezutsu, Tetsuro Shinoda, Takaaki Daimon* (2017) Severe developmental timing defects in the prothoracicotropic hormone (PTTH)-deficient silkworm, Bombyx mori. Insect Biochemistry and Molecular Biology 87: 14-25. (*, corresponding author)
41. Tomohiro Inui, Takaaki Daimon* (2017) Implantation assays using the integument of early stage Bombyx larvae: insights into the mechanisms underlying the acquisition of competence for metamorphosis. Journal of Insect Physiology 100: 35-42. (*, corresponding author)
総説：
11. Xavier Belles, Takaaki Daimon (2022) What triggers metamorphosis in cave insects? A work program. Boletín de la Asociación española de Entomología 4: 116–121.
10.大門高明 (2022)カイコの眠性決定機構. 蚕糸・昆虫バイオテック 91(2): 85-90.
9. 大門高明 (2021)カイコの脱皮回数が決まる仕組み. B&I バイオサイエンスとインダストリー 79(4): 294-295.
8. 大門高明 (2017)ゲノム編集と昆虫の変態制御. アグリバイオ 1(14): 34-38.
7. 大門高明 (2016) 胚子期・若齢期における幼若ホルモンの機能. 蚕糸・昆虫バイオテック 85(3): 101-106.
書籍：
7. 大門高明 (2020) カイコは眠る. 「カイコの科学」（日本蚕糸学会 編）、朝倉書店、pp. 56-57.
6. 藤井毅、大門高明 (2019) カイコの性フェロモンの実験. 生物の科学 遺伝 別冊 No.23 「カイコの実験単」（監修 日本蚕糸学会）、エヌ・ティー・エス pp. 252-257.
5. 大門高明 (2016) 昆虫でのゲノム編集. 実験医学増刊「All about ゲノム編集」（真下知士、山本卓 編）、羊土社 pp. 83-89.
（大門高明；京大にくる前）
原著論文：
40. Takaaki Daimon†, Miwa Uchibori, Nakao Hajime, Hideki Sezutsu, Tetsuro Shinoda (2015) Knockout silkworms reveal a dispensable role for juvenile hormones in holometabolous life cycle. Proceedings of the National Academy of Sciences, U S A. 112(31):E4226-35. († corresponding author)
39. Sora Enya, Takaaki Daimon, Fumihiko Igarashi, Hiroshi Kataoka, Miwa Uchibori, Hideki Sezutsu, Tetsuro Shinoda, and Ryusuke Niwa (2015) The silkworm glutathione S-transferase gene noppera-bo is required for ecdysteroid biosynthesis and larval development. Insect Biochemistry and Molecular Biology 61: 1-7.
38. Shota Nakade, Takuya Tsubota, Yuto Sakane, Satoshi Kume, Naoaki Sakamoto, Masanobu Obara, Takaaki Daimon, Hideki Sezutsu, Takashi Yamamoto, Tetsushi Sakuma, Ken-ichi T. Suzuki (2014) MMEJ-mediated integration of donor DNA in cells and animals using TALENs and CRISPR/Cas9. Nature Communications 5: 5560.
37. Shinichi Yoda, Junichi Yamaguchi, Kazuei Mita, Kimiko Yamamoto, Yutaka Banno, Toshiya Ando, Takaaki Daimon, Haruhiko Fujiwara (2014) The transcription factor Apontic-like controls diverse colouration pattern in caterpillars. Nature Communications 5:4936.
36. Shigehiro Namiki, Takaaki Daimon, Chika Iwatsuki, Toru Shimada, Ryohei Kanzaki (2014) Antennal lobe organization and pheromone usage in bombycid moths. Biology Letters 10(4):20140096.
35. Vlastimil Smykal, Takaaki Daimon, Takumi Kayukawa, Keiko Takaki, Tetsuro Shinoda, Marek Jindra (2014) Importance of juvenile hormone signaling arises with competence of insect larvae to metamorphose. Developmental Biology 390(2): 221-230.
34. Sonja Bisch-Knaden, Takaaki Daimon, Toru Shimada, Bill Hansson, and Slike Sachse. (2014) Anatomical and functional analysis of domestication effects on the olfactory system of the silkworm Bombyx mori. Proceedings of the Royal Society B. 281(1774): 20132582.
33. Yoko Takasu, Suresh Sajwan, Takaaki Daimon, Mizuko Osanai-Futahashi, Keiro Uchino, Hideki Sezutsu, Toshiki Tamura, and Michal Zurovec (2013) Efficient TALEN construction for Bombyx mori gene targeting. PLoS One 8: e73458.
32. Suetsugu Y, Futahashi R, Kanamori H, Kadono-Okuda K, Sasanuma S, Narukawa J, Ajimura M, Jouraku A, Namiki N, Shimomura M, Sezutsu H, Osanai-Futahashi M, Suzuki M.G, Daimon T, Shinoda T, Taniai K, Asaoka K, Niwa R, Kawaoka S, Katsuma S, Tamura T, Noda H, Kasahara M, Sugano S, Suzuki Y, Fujiwara H, Kataoka H, Arunkumar K.P, Tomar A, Nagaraju J, Goldsmith M.R, Feng Q, Xia Q, Yamamoto K, Shimada T, Mita K (2013) Large scale full-Length cDNA sequencing reveals a unique genomic landscape in a lepidopteran model insect, Bombyx mori. G3: Genes, Genomes, Genetics 3: 1481-1492.
31. Chikara Hirayama, Hiroshi Ono, Yan Meng, Toru Shimada, and Takaaki Daimon (2013) Flavonoids from the cocoon of Rondotia menciana. Phytochemistry 94: 108-112.
30. Lingyan Wang, Takashi Kiuchi, Tsuguru Fujii, Takaaki Daimon, Muwang Li, Yutaka Banno, Shingo Kikuta, Takahiro Kikawada, Susumu Katsuma, and Toru Shimada (2013) Mutation of a novel ABC transporter gene is responsible for the failure to incorporate uric acid in the epidermis of ok mutants of the silkworm, Bombyx mori. Insect Biochemistry and Molecular Biology 43: 562-571.
29. Lingyan Wang, Takashi Kiuchi, Tsuguru Fujii, Takaaki Daimon, Muwang Li, Yutaka Banno, Susumu Katsuma, and Toru Shimada (2013) Reduced expression of the dysbindin–like gene in the Bombyx mori ov , mutant exhibiting mottled translucency of the larval skin. Genome 56:101-108.
28. Takaaki Daimon†, Takeshi Fujii, Tsuguru Fujii, Takeshi Yokoyama, Susumu Katsuma, Tetsuro Shinoda, Toru Shimada, and Yukio Ishikawa (2012) Reinvestigation of the sex pheromone of the wild silkmoth Bombyx mandarina: The effects of bombykal and bombykyl acetate. Journal of Chemical Ecology 38: 1031-1035. († Corresponding author)
27. Takaaki Daimon*†, Takeshi Fujii*, Masaya Yago, Yu-Feng Hsu, Yumiko Nakajima, Tsuguru Fujii, Susumu Katsuma, Yukio Ishikawa, and Toru Shimada (2012) Female sex pheromone and male behavioral responses of the bombycid moth Trilocha varians: comparison with those of the domesticated silkmoth Bombyx mori. Naturwissenschaften 99: 207-215. (*equal contribution, † corresponding author).
本論文で解析したイチジクカサンの写真が、掲載号の表紙を飾りました。
26. Takaaki Daimon, Toshinori Kozaki, Ryusuke Niwa, Isao Kobayashi, Kenjiro Furuta, Toshiki Namiki, Keiro Uchino, Yutaka Banno, Susumu Katsuma, Toshiki Tamura, Kazuei Mita, Hideki Sezutsu, Masayoshi Nakayama, Kyo Itoyama, Toru Shimada, and Tetsuro Shinoda (2012) Precocious metamorphosis in the juvenile hormone-deficient mutant of the silkworm, Bombyx mori. PLoS Genetics 8(3): e1002486.
本論文で解析したカイコの２眠蚕変異体の写真が、掲載号のトップページ（表紙）に選ばれました。
25. Takaaki Daimon†, Masaya Yago, Yu-Feng Hsu, Tsuguru Fujii, Yumiko Nakajima, Ryuhei Kokusho, Hiroaki Abe, Susumu Katsuma, and Toru Shimada† (2012). Molecular phylogeny, laboratory rearing, and karyotype of the bombycid moth Trilocha varians. Journal of Insect Science 12: 49. († Corresponding authors)
24. Masashi Iwanaga, Tomoyuki Hitotsuyama, Susumu Katsuma, Genki Ishihara, Takaaki Daimon, Toru Shimada, Shigeo Imanishi, and Hideki Kawasaki (2011) Infection study of Bombyx mori macula-like virus (BmMLV) using a BmMLV-negative cell line and an infectious cDNA clone. Journal of Virological Methods 179(2):316-24.
23. Ken-ichiro Tatematsu, Kimiko Yamamoto, Keiro Uchino, Junko Narukawa, Tetsuya Iizuka, Yutaka Banno, Susumu Katsuma, Toru Shimada, Toshiki Tamura, Hideki Sezutsu, and Takaaki Daimon† (2011) Positional cloning of silkworm white egg 2 (w-2) locus shows functional conservation and diversification of ABC transporters for pigmentation in insects. Genes to Cells 16(4):331-42.(† Corresponding author)
22. Kei Urano, Takaaki Daimon, Yutaka Banno, Kazuei Mita, Tohru Terada, Kentaro Shimizu, Susumu Katsuma, and Toru Shimada (2010) Molecular defect of isovaleryl-CoA dehydrogenase in the skunk mutant of silkworm, Bombyx mori. FEBS Journal 277(21): 4452-4463.
21. Takaaki Daimon*, Chikara Hirayama*, Masatoshi Kanai, Yoshinao Ruike, Yan Meng, Eiichi Kosegawa, Masatoshi Nakamura, Gozoh Tsujimoto, Susumu Katsuma, and Toru Shimada (2010) The silkworm Green b locus encodes a quercetin 5-O-glucosyltransferase that produces green cocoons with UV-shielding properties. Proceedings of the National Academy of Sciences of the United States of America 107(25): 11471-11476. (*equal contribution)
20. Takaaki Daimon, Masao Mitsuhiro, Susumu Katsuma, Hiroaki Abe, Kazuei Mita, and Toru Shimada (2010) Recent transposition of yabusame, a novel piggyBac-like transposable element in the genome of the silkworm Bombyx mori. Genome 53(8): 585-593.
19. Tsuguru Fujii, Takaaki Daimon, Keiro Uchino, Yutaka Banno, Susumu Katsuma, Hideki Sezutsu, Toshiki Tamura, and Toru Shimada (2010) Transgenic analysis of the BmBLOS2 gene that governs the translucency of the larval integument of the silkworm, Bombyx mori. Insect Molecular Biology 19(5): 659-667.
18. Yan Meng, Susumu Katsuma, Takaaki Daimon, Yutaka Banno, Keiro Uchino, Hideki Sezutsu, Toshiki Tamura, Kazuei Mita, and Toru Shimada (2009) The silkworm mutant lemon (lemon lethal) is a potential insect model for human Sepiapterin reductase deficiency. Journal of Biological Chemistry 284(17): 11698 -11705.
17. Susumu Katsuma, Tadashi Nakanishi, Takaaki Daimon, and Toru Shimada (2009) N-linked glycans located in the pro-region of Bombyx mori nucleopolyhedrovirus V-CATH are essential for the proper folding of V-CATH and V-CHIA. Journal of General Virology 90(1): 170-176.
16. The International Silkworm Genome Consortium (2008) The genome of a lepidopteran model insect, the silkworm Bombyx mori. Insect Biochemistry and Molecular Biology 38(12; Special Issue on the Silkworm Genome): 1036-1045.
15. Ryo Futahashi*, Jotaro Sato*, Yan Meng*, Shun Okamoto, Takaaki Daimon, Kimiko Yamamoto, Yoshitaka Suetsugu, Junko Narukawa, Hirokazu Takahashi, Yutaka Banno, Susumu Katsuma, Toru Shimada, Kazuei Mita, and Haruhiko Fujiwara (2008) yellow and ebony are the responsible genes for the larval color mutants of the silkworm Bombyx mori. Genetics 180(4): 1995-2005. (* These authors contributed equally to this work)
14. K P Arunkumar, Archana Tomar, Takaaki Daimon, Toru Shimada, and J Nagaraju (2008) WildSilkbase: An EST database of wild silkmoths. BMC Genomics 9: 338.
13. Takaaki Daimon, Tomohiro Taguchi, Yan Meng, Susumu Katsuma, Kazuei Mita, and Toru Shimada (2008) Beta-fructofuranosidase genes of the silkworm, Bombyx mori: Insight into enzymatic adaptation of B. mori to toxic alkaloids in mulberry latex. Journal of Biological Chemistry 283(22): 15271-15279.
12. Shinpei Kawaoka, Susumu Katsuma, Takaaki Daimon, Ryoko Isono, Naoko Omuro, Kazuei Mita, and Toru Shimada (2008) Functional analysis of four Gloverin-like genes in the silkworm, Bombyx mori. Archives of Insect Biochemistry and Physiology 67(2): 87-96.
11. Yan Meng, Naoko Omuro, Shunsuke Funaguma, Takaaki Daimon, Shinpei Kawaoka, Susumu Katsuma and Toru Shimada (2008) Prominent down-regulation of storage protein genes after bacterial challenge in eri-silkworm, Samia cynthia ricini. Archives of Insect Biochemistry and Physiology 67(1): 9-19.
10. Takaaki Daimon, Susumu Katsuma, WonKyung Kang, and Toru Shimada (2007) Functional characterization of chitinase from Cydia pomonella granulovirus. Archives of Virology 152(9): 1655-1664.
9. Takaaki Daimon, Susumu Katsuma, and Toru Shimada (2007) Mutational analysis of active site residues of chitinase from Bombyx mori nucleopolyhedrovirus. Virus Research 124(1-2): 168-175.
8. Susumu Katsuma, Takaaki Daimon, Satoshi Horie, Michihiro Kobayashi, and Toru Shimada (2006) N-linked glycans of Bombyx mori nucleopolyhedrovirus fibroblast growth factor are crucial for its secretion. Biochemical and Biophysical Research Communications 350(4): 1069-1075.
7. Susumu Katsuma, Satoshi Horie, Takaaki Daimon, Masashi Iwanaga, and Toru Shimada (2006) In vivo and in vitro analyses of a Bombyx mori nucleopolyhedrovirus mutant lacking functional vfgf. Virology 355(1): 62-70.
6. Takaaki Daimon, Susumu Katsuma, WonKyung Kang, and Toru Shimada (2006) Comparative studies of Bombyx mori nucleopolyhedrovirus chitinase and its host ortholog, BmChi-h. Biochemical and Biophysical Research Communications 345(2): 825-833.
5. Susumu Katsuma, Takaaki Daimon, Kazuei Mita, and Toru Shimada (2006) Lepidopteran ortholog of Drosophila Breathless is a receptor for the baculoviral fibroblast growth factor. Journal of Virology 80(11): 5474-5481.
4. Takaaki Daimon, Susumu Katsuma, Masashi Iwanaga, WonKyung Kang, and Toru Shimada (2005) The BmChi-h gene, a bacterial-type chitinase gene of Bombyx mori, encodes a functional exochitinase that plays a role in the chitin degradation during the molting process. Insect Biochemistry and Molecular Biology 35(10): 1112-1123.
3. Manabu Ote, Kazuei Mita, Hideki Kawasaki, Takaaki Daimon, Masahiko Kobayashi, and Toru Shimada (2005) Identification of molting fluid carboxypeptidase A (MF-CPA) in Bombyx mori. Comparative Biochemistry and Physiology (Part B) 141(3): 314-322.
2. Susumu Katsuma, Shinichiro Tanaka, Naoko Omuro, Lisa Takabuchi, Takaaki Daimon, Shigeo Imanishi, Shuichi Yamashita, Masashi Iwanaga, Kazuei Mita, Susumu Maeda, Masahiko Kobayashi, and Toru Shimada (2005) Novel macula-like virus identified in Bombyx mori cultured cells. Journal of Virology 79(9): 5577-5584.
1. Takaaki Daimon, Koutaro Hamada, Kazuei Mita, Kazuhiro Okano, Masataka G. Suzuki, Masahiko Kobayashi, and Toru Shimada (2003) A Bombyx mori gene, BmChi-h, encodes a protein homologous to bacterial and baculovirus chitinases. Insect Biochemistry and Molecular Biology 33(8): 749-759.
総説：
6. 篠田徹郎、大門高明、古田賢次郎 (2015) 生合理的殺虫剤の標的としての幼若ホルモン関連分子. 日本農薬学会誌 40: 58-67.
5. Takaaki Daimon†, Takashi Kiuchi, and Yoko Takasu (2014) Recent progress in genome engineering techniques in the silkworm, Bombyx mori. Develpment, Growth, and Differentiation 56(1):14-25. († Corresponding author)
4. 大門高明 (2014) カイコガ亜科のバイオロジーと性フェロモン (2014) 蚕糸・昆虫バイオテック 83(2), 105-114.
3. Takaaki Daimon†, and Tetsuro Shinoda (2013) Function, diversity, and application of insect juvenile hormone epoxidases (CYP15). Biotechnology and Applied Biochemistry. 60: 82-91. († Corresponding author)
2. 大門高明 (2011) カイコの笹繭の分子基盤．蚕糸・昆虫バイオテック 79 (2):131-133.
1. 平山力・大門高明・嶋田 透（2011）カイコ繭フラボノイドの生成機構と生理機能．ファインケミカル 40(2): 23-28.
著書：
4. 大門高明 (2015) カイコでのゲノム編集. 実験医学別冊「論文だけではわからないゲノム編集成功の秘訣Q&A」(山本卓 編)、羊土社. pp. 202–217
3. Takaaki Daimon (2015) Highly efficient targeted gene disruption in the silkworm, Bombyx mori, using genome editing tools. In Targeted genome editing using site-specific nucleases (T. Yamamoto ed.) Springer. pp. 81-96. (Book Chapter)
2. 大門高明 (2014) カイコにおけるTALENを用いた遺伝子改変. 実験医学別冊 最強のステップUPシリーズ「今すぐ始めるゲノム編集」TALEN＆CRISPR/Cas9の必須知識と実験プロトコール(山本卓 編)、羊土社、pp.140-148.
1. 大門高明（2009）比較ゲノム解析（1.3.4）、「分子昆虫学」（神村学、日本典秀 、葛西真治、竹内秀明、畠山正統、石橋純 編）、共立出版、24-26.
大出高弘
学会発表リストはresearchmapをご参照ください。
原著論文：
4. Ohde, T.*, Mito, T. & Niimi, T. (2022) A hemimetabolous wing development suggests the wing origin from lateral tergum of a wingless ancestor. Nat. Commun. 13, 979. https://doi.org/10.1038/s41467-022-28624-x
京都大学/徳島大学/基礎生物学研究所の三機関共同プレスリリースはこちら
3. Ohde, T.*, Minemura, T., Hirose, E., Daimon, T. (2020) Egg Microinjection and Efficient Mating for Genome Editing in the Firebrat Thermobia domestica. J. Vis. Exp. 164, e61885. DOI:10.3791/61885. PDF
2. Ohde, T., Morita, S., Shigenobu, S., Morita, J., Mizutani, T., Gotoh, H. Zinna, R. A., Nakata, M., Ito, Y., Wada, K., Kitano, Y., Yuzaki, K., Toga, K., Mase, M., Kadota, K., Rushe, J., Lavine, L. C., Emlen, D. J. and Niimi T. (2018) Rhinoceros beetle horn development reveals deep parallels with dung beetles. PLoS Genet., 14(10): e1007651. DOI: 10.1371/journal.pgen.1007651
Yahooニュースの紹介記事はこちら; 基礎生物学研究所のプレスリリースはこちら
1. Ohde, T.*, Takehana, Y., Shiotsuki, T. and Niimi T. (2018) CRISPR/Cas9-based heritable targeted mutagenesis in Thermobia domestica: A genetic tool in an apterygote development model of wing evolution. Arthropod Struct. Dev., 47, 362–369. DOI: 10.1016/j.asd.2018.06.003 PDF
Preprint：
1. Ohde, T.*, Mito, T., Niimi, T. (2021) A wing growth organizer in a hemimetabolous insect suggests wing origin. Preprint at bioRxiv DOI: https://doi.org/10.1101/2021.03.10.434860 >>> [原著論文4として出版]
和文総説：
1. 大出高弘 (2018) 昆虫翅の進化的起源の探索 —進化発生学が拓く新展開— . 蚕糸・昆虫バイオテック 87, 103–108. PDF
書籍：
1. 大出高弘・新美輝幸 (2020) 2.5.7 昆虫の上陸と翅の獲得. 動物の事典 (末松隆志 編), 朝倉書店.
その他：
2. 2020年8月12日の京都新聞夕刊「科学で感じる四季」のコーナーに記事を掲載していただきました。
基生研・進化発生研究部門在籍時に関わらせていただいたカブトムシの研究を中心に話題提供しました。
（記事は京都新聞社より提供、許可を得て転載）
1. 2019年度京都大学ELCAS個人型を担当しました
京都大学の高校生向け体験型学習講座ELCASで「応用昆虫生理学：最強のカブトムシ飼育プロトコルを作ろう！」を開講しました。受講生2名の論文は京大のリポジトリKURENAIから閲覧できます。
Yuki Kato (2020) How clock genes affect the horn length in the Japanese rhinoceros beetle, Trypoxylus dichotomus? ELCAS Journal, 5, 15–19. PDF
黒瀬淳平 (2020) 飼育土壌が与えるカブトムシ形態への影響評価. ELCAS Journal, 5, 12–14. PDF
（大出高弘；京大にくる前）
原著論文：
8. Minakuchi, C., Ohde, T., Miura, K., Tanaka, T. and Niimi, T. (2015) Role of scalloped in post-embryonic development of the red flour beetle Tribolium castaneum (Coleoptera: Tenebrionidae). Appl. Entomol. Zool., 50, 17–26. DOI: 10.1007/s13355-014-0297-4
7. Ohde, T., Yaginuma, T. and Niimi, T. (2013) Insect morphological diversification through the modification of wing serial homologs. Science, 340, 495–498. (F1000 Recommended) DOI: 10.1126/science.1234219
6. Ito, Y., Harigai, A., Nakata, M., Hosoya, T., Araya, K., Oba, Y., Ito, A., Ohde, T., Yaginuma, T. and Niimi, T. (2013) The role of doublesex in the evolution of exaggerated horns in the Japanese rhinoceros beetle. EMBO Rep., 14, 561–567. DOI: 10.1038/embor.2013.50
5. Osanai-Futahashi, M., Ohde, T., Hirata, J., Uchino, K., Futahashi, R., Tamura, T., Niimi, T. and Sezutsu, H. (2012) A visible dominant marker for insect transgenesis. Nat. Commun., 3, 1295. DOI: 10.1038/ncomms2312
4. Masumoto, M., Ohde, T., Shiomi, K., Yaginuma, T. and Niimi, T. (2012) A baculovirus immediate-early gene, ie1, promoter drives efficient expression of a transgene in both Drosophila melanogaster and Bombyx mori. PLoS ONE, 7, e49323. DOI: 10.1371/journal.pone.0049323
3. Ohde, T., Yaginuma, T. and Niimi, T. (2011) Nymphal RNAi analysis reveals novel function of scalloped in antenna, cercus and caudal filament formation in the firebrat, Thermobia domestica. J. Insect Biotechnol. Sericol., 80, 101–108. DOI: 10.11416/jibs.80.3_101
2. Ohde, T., Masumoto, M., Yaginuma, T. and Niimi, T. (2009) Embryonic RNAi analysis in the firebrat, Thermobia domestica: Distal-less is required to form caudal filament. J. Insect Biotechnol. Sericol., 78, 763–769. DOI: 10.11416/jibs.78.2_99
1. Ohde, T., Masumoto, M., Morita-Miwa, M., Matsuura, H., Yoshioka, H., Yaginuma, T. and Niimi, T. (2009) Vestigial and scalloped in the ladybird beetle: a conserved function in wing development and a novel function in pupal ecdysis. Insect Mol. Biol., 18, 571–581. DOI: 10.1111/j.1365-2583.2009.00898.x
英文総説：
2. Tomoyasu, Y., Ohde, T. and Clark-Hachtel, C. (2017) What serial homologs can tell us about the origin of insect wings. F1000Research, 6, 1–11. doi:10.12688/f1000research.10285.1
1. Ohde, T., Yaginuma, T. and Niimi, T. (2014) Wing serial homologs and the origin and evolution of the insect wing. Zoology, 117, 93–94. doi:10.1016/j.zool.2013.11.001
和文総説：
7. 大出高弘・新美輝幸 (2016) 昆虫の翅の起源はどこか？ 昆虫と自然、51, 4–7.
6. 間瀬睦月・大出高弘・新美輝幸 (2016) 性決定遺伝子で探るカブトムシの角形成メカニズム. 化学と生物, 54, 586–590.
5. 間瀬睦月・大出高弘・新美輝幸 (2015) カブトムシの性差決定遺伝子に関する研究—なぜオスだけに角ができるのか？ 昆虫と自然, 50, 27–29.
4. 大出高弘、柳沼利信、新美輝幸 (2013) 昆虫の翅はどこから来たのか？—エボデボで解き明かす. 生物の科学 遺伝, 67, 222–228.
3. 大出高弘、柳沼利信、新美輝幸 (2010) 無翅昆虫から探る昆虫の翅の起源. 昆虫DNA研究会ニュースレター, 13, 33–36.
2. 新美輝幸、大出高弘、柳沼利信 (2010) 新規生物農薬「翅なしテントウムシ」の作出. ニューカントリー, 57, 70–71.
1. 大出高弘、増本三香、新美輝幸 (2009) 昆虫翅形成遺伝子scallopedの蛹脱皮における新機能 ―TEADタンパク質の新展開―. 比較内分泌学, 35, 269–273.
（佐久間正幸 前教授 〜2016.3)
16. Yoshida, A., Tejima, S., Sakuma, M., Sakamaki, Y., Kodama, R. (2017) Coherent array of branched filamentary scales along the wing margin of a small moth. The Science of Nature, 104: 27.
15. Tejima, S., Ono, T., and Sakuma M. (2016) Antennal mechanosensors mediate sex pheromone‐induced upwind orientation in the potato tuberworm moth. Physiol. Entomol., 42: 113-124.
14. Tejima, S., Ono, T. and Sakuma, M. (2013) Aim-then-shoot anemotaxis involved in the hopping approach of potato tuberworm moth Phthorimaea operculella to a sex pheromone source. Physiol. Entomol., 38: 269-360.
13. Liu, J. and Sakuma, M. (2013) Olfactory conditioning with single chemicals in the German cockroach, Blattella germanica (Dictyoptera: Blattellidae). Appl. Entomol. Zool., 48: 387-396.
12. Suzuki, T., Kojima, T., Takeda, M. and Sakuma, M. (2013) Photo-orientation regulates seasonal habitat selection in the two-spotted spider mite, Tetranychus urticae. J. Exp. Biol., 216: 977-983.
11. Nakajima, Y., Sakuma, M., Sasaki, R. and Fujisaki, K. (2010) Adaptive traits of Riptortus pedestris nymphs (Heteroptera: Alydidae) for locating host plants. Ann. Entomol. Soc. Am., 103: 439 - 448.
10. Okada K. and Sakuma, M. (2009) An odor stimulator controlling odor temporal pattern applicable in insect olfaction study. Chem. Senses, 34: 425-433.
9. Moriyama, T., Kojima,T. and Sakuma,M. (2008) Active antennal searching suggesting anticipatory capability in pill bugs (Armadillidium vulgare). International Journal of Computing Anticipatory Systems, 21: 37 - 44. Dubois, D.M. ed., Liege (ISSN 1373-5411).
8. Fukui,M., Utsumi, N. (2007) Advertisement call recognition with pulse rates in the field cricket Teleogryllus taiwanemma (Insecta: Orthoptera: Gryllidae) Trans. Tech. Comm. Psychol. Physiol. Acoust. 37(4), 265-269.
7. Kojima, T., Sakuma, M., Fukui, M. and Kuwahara, Y. (2003) The spatial orientation of the mould mites, Tyrophagus putrescentidae (Schrank) (Acarina: Acaridae) in the computer-programmed olfactory field. J. Acarol. Soc. Jpn. 12: 93-102.
6. Kugimiya S., R. Nishida, M. Sakuma and Y. Kuwahara (2003) Nutritional phagostimulants function as male courtship pheromone in the German cockroach, Blattella germanica. Chemoecology 13(4): 169-175.
5. Sakuma, M (2002) Virtual reality experiments on a digital servosphere: guiding male silkworm moths to a virtual odour source. Comput. Electron. Agri. 35: 243-254.
4. Kugimiya, S., Nishida, R., Kuwahara, Y. and Sakuma, M. (2002) Phospoholipid composition and pheromonal activity of nuptial secretion of the male German cockroach, Blattella germanic a. Entomol. Exp. Appl., 104: 337-344.
3. Nojima, S., Nishida, R., Sakuma, M. and Kuwahara, Y. (2002) Oligosaccharide composition and pheromonal activity of male tergal gland secretions of the German cockroach, Blattella germanica (L.). J. Chem. Ecol. 28: 1483 - 1494.
2. Nojima, S., Sakuma, M., Nishida, R. and Kuwahara, Y. (1999) A glandular gift in the German cockroach, Blattella germanica (L.) (Dictyoptera: Blattellidae): the courtship feeding of a female on secretions from male tergal glands. J.Insect Behavior. 12: 627- 635.
1. Nuptial feeding simulants: a male courtship pheromone of the German Cockroach, Blattella germanica (L.) (Dictyoptera: Blattellidae). Nojima, S., Nishida, R., Kuwahara, Y. and Sakuma, M. (1999) Naturwissenschaften. 86: 193-196.