Publications

Recent Publications

  • Nietz A, Krook-Magnuson C, Gutierrez H, Klein J, Sauve C, Hoff I, Christenson Wick Z, Krook-Magnuson E

"Selective loss of the GABAAα1 subunit from Purkinje cells is sufficient to induce a tremor phenotype"

Journal of Neurophysiology

09 SEP 2020 https://doi.org/10.1152/jn.00100.2020


  • Zeidler Z, Hoffmann K, Krook-Magnuson E.

"HippoBellum: acute cerebellar modulation alters hippocampal dynamics and function"

Journal of Neuroscience. 2 September 2020, 40 (36) 6910-6926

https://doi.org/10.1523/JNEUROSCI.0763-20.2020

Check out a brief summary in This Week in the Journal. (scroll down)


  • Streng ML, Krook-Magnuson E

"The cerebellum and epilepsy"

Epilepsy & Behavior (2020); https://doi.org/10.1016/j.yebeh.2020.106909

Accepted version of manuscript available here.


  • Streng ML, Krook-Magnuson E

"Excitation, but not inhibition of the fastigial nucleus provides powerful control over temporal lobe seizures"

J Physiol (2020) 598(1): 171-187 [Epub ahead of print: Nov 4, 2019. doi: 10.1113/JP278747 ]

For a plain English explanation of Martha's paper, check out EpilepsyInEnglish's write up of Martha's work here.

To see associated cover art, click here.


  • Francesca Billwiller, Laura Castillo, Heba Elseedy, Anton Ivanovich Ivanov, Jennyfer Scapula, Antoine Ghestem, Julien Carponcy, Paul Antoine Libourel, Hélène Bras, Nabila ElSayed Abdelmeguid, Esther Krook-Magnuson, Ivan Soltesz, Christophe Bernard, Pierre-Hervé Luppi, Monique Esclapez

GABA-glutamate supramammillary neurons control theta and gamma oscillations in the dentate gyrus during paradoxical (REM) sleep

Brain Struct Funct (2020). Published: 24 Sep 2020


  • Ritchie Chen, Felicity Gore, Quynh-Anh Nguyen, Charu Ramakrishnan, Sneha Patel, Soo Hyun Kim, Misha Raffiee, Yoon Seok Kim, Brian Hsueh, Esther Krook-Magnusson, Ivan Soltesz & Karl Deisseroth

Deep brain optogenetics without intracranial surgery

Nature Biotechnology (2020) Published: 05 October 2020


  • Christenson Wick Z, Tetzlaff MR, Krook-Magnuson E

"Novel long-range inhibitory nNOS-expressing hippocampal cells"

eLIFE (2019) Oct 14;8. pii: e46816. doi: 10.7554/eLife.46816

Find associated BrdU protocol published in bio-101 here.


  • Zeidler Z, Brandt-Fontaine M, Leintz C, Krook-Magnuson C, Netoff T, Krook-Magnuson E

"Targeting the Mouse Ventral Hippocampus in the Intrahippocampal Kainic Acid Model of Temporal Lobe Epilepsy"

eNeuro (2018) 0158-18.2018; doi: 10.1523/ENEURO.0158-18.2018


  • Christenson Wick Z and Krook-Magnuson E.

"Specificity, Versatility, and Continual Development: The Power of Optogenetics for Epilepsy Research"

Front. Cell. Neurosci. (2018) doi: 10.3389/fncel.2018.00151


  • Christenson Wick Z, Leintz C, Xamonthiene C, Huang B, Krook-Magnuson E.

"Axonal sprouting in commissurally projecting parvalbumin-expressing interneurons"

Journal of Neuroscience Research. (2017) doi: 10.1002/jnr.24011

To see associated cover art, click here.

Pre-prints not yet out in final form

  • Billwiller F, Castillo L, Elseedy H, Ivanov AI, Scapula J, Ghestem A, Carponcy J, Libourel PA, Bras H, ElSayed Abdelmeguid N, Krook-Magnuson E, Soltesz I, Bernard C, Luppi PH, Esclapez M

"GABA-Glutamate supramammillary neurons control theta and gamma oscillations in the dentate gyrus during paradoxical (REM) sleep"

bioRxiv 584862; doi: https://doi.org/10.1101/584862

Research & Protocol Publications

  • Nietz A, Krook-Magnuson C, Gutierrez H, Klein J, Sauve C, Hoff I, Christenson Wick Z, Krook-Magnuson E

"Selective loss of the GABAAα1 subunit from Purkinje cells is sufficient to induce a tremor phenotype"

Journal of Neurophysiology

09 SEP 2020 https://doi.org/10.1152/jn.00100.2020


  • Zeidler Z, Hoffmann K, Krook-Magnuson E.

"HippoBellum: acute cerebellar modulation alters hippocampal dynamics and function"

Journal of Neuroscience. 2 September 2020, 40 (36) 6910-6926

https://doi.org/10.1523/JNEUROSCI.0763-20.2020

Check out a brief summary in This Week in the Journal. (scroll down)


  • Streng ML, Krook-Magnuson E

"Excitation, but not inhibition of the fastigial nucleus provides powerful control over temporal lobe seizures"

J Physiol (2020) 598(1): 171-187 [Epub ahead of print: Nov 4, 2019. doi: 10.1113/JP278747 ]

For a plain English explanation of Martha's paper, check out EpilepsyInEnglish's write up of Martha's work here.

To see associated cover art, click here.


  • Christenson Wick Z, Tetzlaff MR, Krook-Magnuson E

"Novel long-range inhibitory nNOS-expressing hippocampal cells"

eLIFE (2019) Oct 14;8. pii: e46816. doi: 10.7554/eLife.46816


  • Zeidler Z, Brandt-Fontaine M, Leintz C, Krook-Magnuson C, Netoff T, Krook-Magnuson E

"Targeting the Mouse Ventral Hippocampus in the Intrahippocampal Kainic Acid Model of Temporal Lobe Epilepsy"

eNeuro (2018) 0158-18.2018; doi: 10.1523/ENEURO.0158-18.2018


  • Christenson Wick Z, Leintz C, Xamonthiene C, Huang B, Krook-Magnuson E.

"Axonal sprouting in commissurally projecting parvalbumin-expressing interneurons"

Journal of Neuroscience Research. (2017) doi: 10.1002/jnr.24011

To see associated cover art, click here.


  • Krook-Magnuson E, Armstrong C, Bui A, Lew S, Oijala M, Soltesz I.

"In Vivo Evaluation of the Dentate Gate Theory in Epilepsy. "

Journal of Physiology. (2015) doi: 10.1113/JP270056


  • Krook-Magnuson E, Szabo G, Armstrong C, Oijala M, Soltesz I

"Cerebellar Directed Optogenetic Intervention Inhibits Spontaneous Hippocampal Seizures in a Mouse Model of Temporal Lobe Epilepsy"

eNeuro 2014. DOI: 10.1523/ENEURO.0005-14.2014


  • Armstrong C, Krook-Magnuson E, Oijala M, Soltesz I.

"Closed-loop optogenetic intervention in mice."

Nature Protocol. 2013 Aug;8(8):1475-93. doi: 10.1038/nprot.2013.080. Epub 2013 Jul 11.


  • Krook-Magnuson E, Armstrong C, Oijala M, Soltesz I.

"On-demand optogenetic control of spontaneous seizures in temporal lobe epilepsy."

Nature Communications. 2013;4:1376. doi: 10.1038/ncomms2376.


  • Krook-Magnuson E, Luu L, Lee SH, Varga C, Soltesz I.

"Ivy and neurogliaform interneurons are a major target of μ-opioid receptor modulation."

J Neurosci. 2011 Oct 19;31(42):14861-70. doi: 10.1523/JNEUROSCI.2269-11.2011.


  • Krook-Magnuson EI, Li P, Paluszkiewicz SM, Huntsman MM.

"Tonically active inhibition selectively controls feedforward circuits in mouse barrel cortex."

J Neurophysiol. 2008 Aug;100(2):932-44. doi: 10.1152/jn.01360.2007. Epub 2008 May 28.


  • Krook-Magnuson EI, Huntsman MM.

"Excitability of cortical neurons depends upon a powerful tonic conductance in inhibitory networks."

Thalamus Relat Syst. 2005 Jun;3(2):115-120.

Reviews & Book Chapters

  • Streng ML, Krook-Magnuson E

"The cerebellum and epilepsy"

Epilepsy & Behavior; https://doi.org/10.1016/j.yebeh.2020.106909


  • Christenson Wick Z and Krook-Magnuson E.

"Specificity, Versatility, and Continual Development: The Power of Optogenetics for Epilepsy Research"

Front. Cell. Neurosci. (2018) doi: 10.3389/fncel.2018.00151


  • Yu W and Krook-Magnuson E.

"Cognitive collaborations: bidirectional functional connectivity between the cerebellum and the hippocampus"

Frontiers in Systems Neuroscience. (2015) doi: 10.3389/fnsys.2015.00177


  • Krook-Magnuson E and Soltesz I

"Beyond the hammer and the scalpel: selective circuit control for the epilepsies."

Nature Neuroscience 18, 331–338 (2015) doi:10.1038/nn.3943


  • Krook-Magnuson E, Gelinas J, Soltesz I, Buzsaki G.

"Neuroelectronics and bio-optics: Closed-loop technologies in neurological disorders."

JAMA Neurology (2015) doi:10.1001/jamaneurol.2015.0608


  • Nagaraj V, Lee S, Krook-Magnuson E, Soltesz I, Benquet P, Irazoqui P, Netoff T.

"Future of Seizure Prediction and Intervention: Closing the loop."

Journal of Clinical Neurophysiology. (2015) doi: 10.1097/WNP.0000000000000139


  • Krook-Magnuson E, Ledri M, Soltesz I, Kokaia M.

"How might novel technologies such as optogenetics lead to better treatments in epilepsy?"

Adv Exp Med Biol. 2014;813:319-36. doi: 10.1007/978-94-017-8914-1_26.


  • Armstrong C, Krook-Magnuson E, Soltesz I.

"Neurogliaform and Ivy Cells: A Major Family of nNOS Expressing GABAergic Neurons."

Front Neural Circuits. 2012 May 16;6:23. doi: 10.3389/fncir.2012.00023. eCollection 2012.


  • Krook-Magnuson E, Varga C, Lee SH, Soltesz I.

"New dimensions of interneuronal specialization unmasked by principal cell heterogeneity."

Trends Neurosci. 2012 Mar;35(3):175-84. doi: 10.1016/j.tins.2011.10.005. Epub 2011 Nov 24.


  • Krook-Magnuson E, Huntsman MM.

"The transience of interneuron circuit diversity just "sped" up."

Proc Natl Acad Sci U S A. 2007 Oct 23;104(43):16723-4. Epub 2007 Oct 15.

Commentaries

  • Krook-Magnuson E.

The Devil’s in the Details: How to Harness Inhibition for Seizure Control

Epilepsy Currents (first published Feb 2020); Vol 20, Issue 2, 2020


  • Krook-Magnuson E.

From Point A to Point B, and What it Means for Epilepsy.

Epilepsy Currents (first published Dec 2019); Vol 20, Issue 1, 2020


  • Christenson Wick Z and Krook-Magnuson E.

Seizing Sequencing Data to Consider Cell and Circuity Complexity

Epilepsy Currents March/April 2019, Vol 19, No. 2, pp. 124-125.


  • Richner TJ, Krook-Magnuson E.

"Progress Toward Precise Genetic Repair in Neurons"

Epilepsy Currents March/April 2018, Vol 18, No. 2, pp. 121-122.


  • Zeidler Z, Krook-Magnuson E.

"Back to the Dentate: Network Changes of Early- and Late-Born Dentate Granule Cells"

Epilepsy Currents Jan/Feb 2018, Vol. 18, No. 1, pp. 49-50


  • Yu W. Krook-Magnuson E.

"Targeting Newly Generated Granule Cells: A Double-Edged Sword"

Epilepsy Currents: March/April, Vol. 17, No. 2, pp. 121-123. (2017)



  • Krook-Magnuson E.

"The Gate and the Source? The Dentate Gyrus Takes Central Stage in Temporal Lobe Epilepsy"

Epilepsy Currents: January/February, Vol. 17, No. 1, pp. 48-49. (2017)



  • Krook-Magnuson E.

"Downsides and Downstream Effects of Interictal Epileptiform Discharges"

Epilepsy Currents: September/October, Vol. 16, No. 5, pp. 325-326. (2016)



  • Zeidler Z and Krook-Magnuson E.

"One Site to Rule Them All: Toward a Master Regulator of Ictal Activity"

Epilepsy Currents. (2016) doi: 10.5698/1535-7511-16.3.170