研究業績
【論文】
論文
すべて
1.PCA-based unsupervised feature extraction for gene expression analysis of
COVID-19 patients
Kota Fujisawa, Mamoru Shimo, Y.-H. Taguchi, Shinya Ikematsu, Ryota Miyata
Scientific Reports 11(1),17351(令和3年12月)
2.Screening of novel Midkine binding protein by BioID2-based proximity labeling.
Yosuke Komata, Shoma Tsubota, Kazuma Sakamoto, Shinya Ikematsu, Kenji Kadomatsu
Nagoya journal of medical science 83(3),495~508頁(令和3年8月)
Jasmine F. Millman, Shiki Okamoto, Taiki Teruya, Tsugumi Uema,
Shinya Ikematsu, Michio Shimabukuro, Hiroaki Masuzaki
Nutrition Reviews 79(12),1~13頁(令和3年2月)
4.Gut microbial composition of elderly women born in the Japanese longevity village Ogimi
HirotoMORITA, Mutsuki ICHISHIMA, Ipputa TADA, Hirotsugu SHIROMA, Makoto MIYAGI, Teppei NAKAMURA, Hiroshi TANAKA, Shinya IKEMATSU
Biosci Microbiota Food Health 40(1),75~79頁(令和2年8月)
Kuniaki Nerome, Taku Ito-Kureha, Tiziana Paganini, Takao Fukuda, Yasuhiro Igarashi, Hiroto Ashitomi, Shinya Ikematsu, Tadashi Yamamoto
American Journal of Cancer Research 10(2),581~594頁(令和2年2月)
6.Metabolically and immunologically beneficial impact of extra virgin olive and flaxseed oils on composition of gut microbiota in mice
Millman J , Okamoto S , Kimura A , Uema T , Higa M , Yonamine M , Namba T , Ogata E , Yamazaki S, Shimabukuro M , TsuTsui M , Matsushita M , Ikematsu S , Masuzaki H
Eur J Nutr. 59(6),2411~2425頁(令和元年9月)
7.Changing industrial waste into healthy ingredients-Generating amino acids from soy pulp
Hinako Kawamitsu, Sakura Aragaki, Naruse Shingaki, Yoshiteru Iinuma,
Yuta Yabe, Aoki Kimura, Shinya Ikematsu
journal of Environment and Safety 10(2) ,17~20頁(令和元年6月)
8.Two-dimensional NMR data of a water-soluble β-(1→3, 1→6)-glucan from Aureobasidium pullulans and schizophyllan from Schizophyllum commune
Hiroyuki Kono, Nobuhiro Kondo, Katsuki Hirabayashi, Makoto Ogata, Kazuhide Totani,Shinya Ikematsu, Mitsumasa Osada
Data in Brief,Vol.15, 382~388頁(平成29年12月)
9.NMR spectroscopic structural characterization of a water-soluble β-(1→3, 1→6)-glucan from Aureobasidium pullulans
Kono H , Kondo N , Hirabayashi K , Ogata M , Totani K , Ikematsu S ,
Osada M
Carbohydrate Polymers, Vol.174, 876~886頁(平成29年10月)
10.Efficacy of urinary midkine as a biomarker in patients with acute kidney injury
Hayashi H , Sato W , Kosugi T , Nishimura K , Sugiyama D , Asano N , Ikematsu S , Komori K , Nishiwaki K , Kadomatsu K , Matsuo S , Maruyama S , Yuzawa Y
Clinical and Experimental Nephrology, Vol.21(4),597~607頁
(平成29年8月)
11.Genome Sequence of Lactobacillus paracasei Strain LC-Ikematsu, Isolated from a Pineapple in Okinawa, Japan
Ipputa Tada, Seikoh Saitoh, Hiroaki Aoyama, Naoya Shinzato, Norikuni Yamamoto, Masanori Arita, Shinya Ikematsu
Genome Announcements,Vol.5(5), e01583-16頁(平成29年2月)
12. The CCR4-NOT deadenylase activity contributes to generation of induced pluripotent stem cells
Zukeran A , Takahashi A , Takaoka S , Mohamed HMA ,Suzuki T , Ikematsu S , Yamamoto T
Biochemical and Biophysical Research Communications, 474, 233~239頁
(平成28年5月)
13. Biocompatibility Evaluation of Cellulose Hydrogel Film Regenerated from Sugar Cane Bagasse Waste and Its in Vivo Behavior in Mice
Kazuki Nakasone, Shinya Ikematsu, and Takaomi Kobayashi
Ind. Eng. Chem. Res., Vol.55(1), 30~37頁
(平成28年1月)
14. Expression of midkine in normal human skin, dermatitis, and neoplasms: Association with differentiation of keratinocytes
Fumiko Monma, Yutaka Hozumi, Shinya Ikematsu, Masakazu Kawaguchi, Kenji Kadomatsu, Tamio Suzuki
The Journal of Dermatology, 2013, Dec; 40(12), 980~986頁
(平成25年12月)
15. 血中・尿中ミッドカイン測定系“ミッドカイン”―機能解析から臨床応用へ
池松真也
医学のあゆみ、230(4),285~289頁
(平成21年7月)
16. The growth factor midkine regulates the renin-angiotensin system in mice
Hobo A, Yuzawa Y, Kosugi T, Kato N, Asai N, Sato W, Maruyama S, Ito Y, Kobori H, Ikematsu S, Nishiyama
JClin Invest. 119(6), 1616~1625頁
(平成21年6月)
17. Plasma midkine level is a prognostic factor for human neuroblastoma
Ikematsu S, Nakagawara A, Nakamura Y, Ohira M, Shinjo M, Kishida S,
Kadomatsu K
Cancer Science 99(10), 2070~2074頁
(平成20年10月)
18. Midkine and its clinical significance in endometrial cancer
Tanabe Kojiro,Matsumoto Mitsuyo, Akahira Junichi,Suzuki Takashi,Kadomatsu Kenji,Ikematsu Shinya,Sasano Hironobu,Hayashi Shinichi,Yaegashi Nobuo
Cancer Science 99(6), 1125~1130頁
(平成20年6月)
19. Expression of the Heparin-Binding Growth Factor Midkine in the Cerebrospinal Fluid of Patients with Neurological Disorders
Yoshida Yoshihiro, Ikematsu Shinya, Muramatsu Hisako, Sakakima Harutoshi, Mizuma Nobuhisa, Matsuda Fumiyo, Sonoda Ken, Umehara Fujio, Ohkubo Ryuichi, Matsuura Eiji, Goto Masamichi, Osame Mitsuhiro,Muramatsu Takashi
Internal Medicine、Vol.47 (2), 83~89頁
(平成19年10月)
20. Midkine and LDL receptor-related protein 1 contribute to the anchorage-independent cell growth of cancer cells
Chen S., Bu G., Takei Y., Sakamoto K., Ikematsu S., Muramatsu T., Kadomatsu K.
J Cell Science, Vol.120 (Pt22), 4009~4015頁
(平成19年10月)
21. Midkine as a novel target for antibody therapy in osteosarcoma
Maehara H., Kaname T., Yanagi K., Hanzawa H., Owan I., Kinjou T., Kadomatsu K., Ikematsu S., Iwamasa T., Kanaya F., Naritomi K.
Biochem Biophys Res Commun、Vol.358, 757~762頁
(平成19年7月)
22. Protein tyrosine phosphatase receptor type Z is inactivated by ligand-induced oligomerization
Fukada M., Fujikawa A., Chow JP., Ikematsu S., Sakuma S., Noda M
FEBS Letters, Vol.580, 4051~4056頁
(平成18年6月)
23. Doxorubicin-Conjugated Anti-Midkine Monoclonal Antibody as a Potential Anti-Tumor Drug
Inoh K., Muramatsu H., Torii S., Ikematsu S., Oda M., Kumai H., Sakuma S., Inui T., Kimura T., Muramatsu T.
Jpn J Clin Oncol,Vol.36, 207~211頁
(平成18年4月)
24. Midkine protects hepatocellular carcinoma cells against TRAIL-mediated apoptosis through down-regulation of caspase-3 activity.
Ohuchida,T.,Okamoto,K.,Akahane,K.,Higure,A.,Todoroki,H.,Abe,Y.,
Kikuchi,M.,Ikematsu,S.,Muramatsu,T.,Itoh,H.
Cancer. 2004; 100(11): 2430~2436頁
(平成16年11月)
25. Correlation of elevated level of blood midkine with poor prognostic factors of human neuroblastomas.
Ikematsu S., Nakagawara A., Nakamura Y., Sakuma S., Wakai K., Muramatsu T., Kadomatsu K.
Br J Cancer, Vol.88(10): 1522~1526頁,名古屋大学学位論文
(平成15年10月)
26. Preoperative serum Midkine concentration is a prognostic marker for esophageal squamous cell carcinoma.
Shimada H., Nabeya Y., Tagawa M., Okazumi S., Matsubara H., Kadomatsu K., Muramatsu T., Ikematsu S., Sakuma S., Ochiai T.
Cancer Sci. Vol.94, No. 7: 628~632頁
(平成15年7月)
27. Utilization of the promoter region of the midkine gene as a tool to drive therapeutic genes in a tumor specific manner.
Sakiyama S., Yu L., Tomizawa M., Shimada H., Kadomatsu K., Muramatsu T., Ikematsu S., Nakagawara A., Tagawa M.
Adv.Enzyme Regul. Vol.43, 57~66頁
(平成15年7月)
28. Increased serum midkine concentration as a possible tumor markerin patients with superficial esophageal cancer.
Shimada H., Nabeya Y., Okazumi S., Matsubara H., Kadomatsu K., Muramatsu T., Ikematsu S., Sakuma S., Ochiai T.
Oncol.Rep. Vol.10, No. 2, 411~414頁
(平成15年2月)
29. Receptor-type protein Tyrosine phosphatase zeta as a component of the signaling receptor complex for midkine-dependent survival of embryonic neurons.
Sakaguchi N., Muramatsu H., Ichihara-Tanaka K., Maeda N., Noda M., Yamamoto T., Michikawa M., Ikematsu S., Sakuma S., Muramatsu T.
Neurosci.Res. Vol.45, No. 2, 219~224頁
(平成15年2月)
30. High levels of urinary midkine in various cancer patients.
Ikematsu S., Okamoto K., Yoshida Y., Oda M., Sugano-Nagano H., Ashida K., Kumai H., Kadomatsu K., Muramatsu H., Muramatsu T., Sakuma S.
Biochem.Biophys.Res. Commun., Vol.306, No. 2, 329~332頁
(平成15年2月)
31. Glycosaminoglycan structures required for strong binding to midkine, a heparin-binding growth factor.
Zou P., Zou K., Muramatsu H., Ichihara-Tanaka K., Habuchi O., Ohtake S., Ikematsu S., Sakuma S., Muramatsu T.
Glycobiology, Vol.13, No. 1, 35~42頁
(平成15年1月)
32. Glypican-2 binds to midkine: the role of glypican-2 in neuronal cell adhesion and neurite outgrowth.
Kurosawa N., Chen GY., Kadomatsu K., Ikematsu S., Sakuma S., Muramatsu T.
Glycoconj.J., Vol.18,No. 6, 499~507頁
(平成13年6月)
33. Haptotactic migration induced by midkine. Involvement of protein-tyrosine phosphatase zeta. Mitogen-activated protein kinase, and phosphatidylinositol 3-kinase.
Qi M., Ikematsu S., Maeda N., Ichihara-Tanaka K., Sakuma S., Noda M., Muramatsu T., Kadomatsu K.
J.Biol.Chem., Vol.276, No.19, 15868~15875頁
(平成13年5月)
34. Intraventricular administration of the neurotrophic factor midkine ameliorates hippocampal delayed neuronal death following transient forebrain ischemia in gerbils.
Yoshida Y., Ikematsu S., Moritoyo T., Goto M., Tsutsui J., Sakuma S., Osame M., Muramatsu T.
Brain Res., Vol.894,No.1, 46~55頁
(平成13年1月)
35. Overexpression of midkine in pancreatic duct adenocarcinomas induced by N-Nitrosobis (2-oxopropyl)amine in hamsters and their cell lines.
Tsutsumi M., Kadomatsu K., Tsujiuchi T., Sakitani H., Ikematsu S., Kubozoe T., Yoshimoto M., Muramatsu T., Sakuma S., Konishi Y.
Jpn.J.Cancer Res., Vol.91, No.10, 979~986頁
(平成12年10月)
36. 神経栄養因子ミドカイン(MK)のスナネズミ遅発性神経細胞死に対する抑制作用
吉田義弘、池松真也、森豊隆志、後藤正道、筒井順一郎、佐久間貞俊、納光弘、
村松喬
Brain Hypoxia,Vol.14,55~61頁
(平成12年8月)
37. A heparin-binding growth factor, midkine, binds to a chondroitin sulfate proteoglycan, PG-M/versican.
Zou K., Muramatsu H., Ikematsu S., Sakuma S., Salama RH., Shinomura T., Kimata K., Muramatsu T.
Eur.J.Biochem., Vol.267, No.13, 4046~4053頁
(平成12年7月)
38. Serum midkine levels are increased in patients with various types of carcinomas.
Ikematsu S., Yano A., Aridome K., Kikuchi M., Kumai H., Nagano H., Okamoto K., Oda M., Sakuma S., Aikou T., Muramatsu H., Kadomatsu K., Muramatsu T.
Br.J.Cancer, Vol.83, No. 6, 701 ~ 706頁
(平成12年6月)
39. An approach to the removal of Yeast specific O-linked oligo-mannoses from human midkine expressed in Pichia pastoris using site-specific mutagenesis.
Asami Y., Nagano H., Ikematsu S., Murasugi A.
J.Biochem., Vol.128, No. 5, 823 ~ 826頁
(平成12年5月)
40. Neointima formation ina restenosis model is suppressed in midkine-deficient mice.
Horiba M., Kadomatsu K., Nakamura E., Muramatsu H., Ikematsu S., Sakuma S., Hayashi K., Yuzawa Y., Matsuo S., Kuzuya M., Kaname T., Hirai M., Saito H., Muramatsu T.
J.Clin.Invest., Vol.105, No. 4, 489 ~ 495頁
(平成12年4月)
41. LDL receptor-related protein as a component of the midkine receptor.
Muramatsu H., Zou K., Sakaguchi N., Ikematsu S., Sakuma S., Muramatsu T.
Biochem.Biophys.Res. Commun., Vol.270, No. 3, 936 ~ 941頁
(平成12年3月)
42. Midkine rescues Wilms’tumor cells from cisplatin-induced apoptosis:regulation of Bcl-2 expression by Midkine.
Qi M., Ikematsu S., Ichihara-Tanaka K., Sakuma S., Muramatsu T., Kadomatsu K.
J.Biochem. Vol.127, No. 2, 269 ~ 277頁
(平成12年2月)
43. Midkine binds specifically to sulfatide the role of sulfatide in cell attachment to midkine-coated surfaces.
Kurosawa N., Kadomatsu K., Ikematsu S., Sakuma S., Kimura T., Muramatsu T.
Eur.J.Biochem., Vol.267, No. 2, 344 ~ 351頁
(平成12年2月)
44. Frequent expression of midkine gene in esophageal cancer suggests a potential usage of its promoter for suicide gene therapy.
Miyauchi M., Shimada H., Kadomatsu K., Muramatsu T., Matsubara S.,Ikematsu S., Takenaga K., Asano T., Ochiai T., Sakiyama S., Tagawa M.
Jpn.J.Cancer Res., Vol.90, No. 4, 469 ~ 475頁
(平成11年4月)
45. Overexpression of midkine in lung tumors induced by N-nitrosobis(2-hydroxypropyl)amine in rats and its increase with progression
Sakitani H., Tsutsumi M., Kadomatsu K., Ikematsu S., Takahama M., Iki K., Tsujiuchi T., Muramatsu T., Sakuma S., SakakiT., Konishi Y.
Carcinogenesis,Vol.20, No. 3, 465 ~ 469頁
(平成11年3月)
46. 神経栄養因子ミドカイン(MK)のスナネズミ遅発性神経細胞死に対する抑制作用
吉田義弘、池松真也、王沙燕、後藤正道、筒井順一郎、村松喬、納光弘
脳卒中20巻、6号,720 ~ 724頁
(平成10年6月)
47. transgenic mouse line with alpha-1,3/4-fucosyltransferase cDNA production
and characteristics.
Obama H., Kaname T., Sudou A., Yanagida T., Ikematsu S.,Ozawa M., Yoshida H., Kannagi R., Yamamura K., Muramatsu T.
Glycoconjugate J.Vol.12, No. 6, 795 ~ 801頁
(平成7年6月)
48. Transgenic mouse Lines with ectopic Expression of alpha-1,3-galactosyltransferase: production and characteristics.
Ikematsu S., Kaname T., Ozawa M., Yonezawa S., Sato E., Uehara F., Obama H., Yamamura K., Muramatsu T
Glycobiology,Vol.3(6), 575 ~ 580頁,鹿児島大学修士論文
(平成5年6月)
2023年度
バイオインフォマティクスによる天然物由来の評価と化粧品・機能性素材への応用
池松真也
Cosmetic stage / 技術情報協会 編 (4), 37-41, 2023-04
「ライフサイエンス研究拠点」構築に挑む
池松真也, 村山裕子, 安田直子, 河本絵美
日本高専学会誌 Journal of the Japan Association for Collage of Technology 28 (2), 19-22, 2023-04
バイオインフォマティクスによる天然物由来の評価と化粧品・機能性素材への応用
池松 真也
コスメティックステージ 17(4) 37-41 2023年4月25日 筆頭著者
ブルーゾーン大宜味村の腸内細菌叢解析から見えてくるもの
池松 真也
アグリバイオ 7(5) 33-38 2023年5月 筆頭著者
2022年度
2021年度
Extra-virgin olive oil and the gut-brain axis: influence on gut microbiota, mucosal immunity, and cardiometabolic and cognitive health
Jasmine F. Millman, Shiki Okamoto, Taiki Teruya, Tsugumi Uema, Shinya Ikematsu, Michio Shimabukuro, Hiroaki Masuzaki
Nutrition Reviews 1-13 2021年2月12日
水熱処理黒酵母β-グルカン「KBG」の開発と応用研究について【総説:―受賞論文―】
近藤 修啓, 甲野 裕之, 池松 真也, 戸谷 一英, 尾形 慎
応用糖質科学 11(1) 50-55 2021年2月20日
PCA-based unsupervised feature extraction for gene expression analysis of COVID-19 patients
Kota Fujisawa, Mamoru Shimo, Y.-H. Taguchi, Shinya Ikematsu, Ryota Miyata
Scientific Reports 11(1) 2021年12月
Screening of novel Midkine binding protein by BioID2-based proximity labeling
Yosuke Komata, Shoma Tsubota, Kazuma Sakamoto, Shinya Ikematsu, Kenji Kadomatsu
Nagoya journal of medical science 83(3) 495-508 2021年8月
2020年度
Potent and broad anticancer activities of leaf extracts from Melia azedarach L. of the subtropical Okinawa islands
Kuniaki Nerome, Taku Ito-Kureha, Tiziana Paganini, Takao Fukuda, Yasuhiro Igarashi, Hiroto Ashitomi, Shinya Ikematsu, Tadashi Yamamoto
American Journal of Cancer Research 10(2) 581-594 2020年2月15日
バイオインダストリー
池松真也
"琉れん草" 有効成分を活用したサプリメント開発 (沖縄生物資源の産業利用) 37(12) 11-19 2020年12月
Gut microbial composition of elderly women born in the Japanese longevity village Ogimi
Hiroto MORITA, Mutsuki ICHISHIMA, Ipputa TADA, Hirotsugu SHIROYAMA, Makoto MIYAGI, Teppei NAKAMURA, Hiroshi TANAKA, Shinya IKEMATSU
Biosci Microbita Food Health 40(1) 75-79 2020年8月
2019年度
Metabolically and immunologically beneficial impact of extra virgin olive and flaxseed oils on composition of gut microbiota in mice
Millman J, Okamoto S, Kimura A, Uema T, Higa M, Yonamine M, Namba T, Ogata E, Yamazaki S, Shimabukuro M, Tsutsui M, Matsushita M, Ikematsu S, Masuzaki H
Eur J Nutr 2019年9月
journal of Environment and Safety 10(2) 17-20 2019年6月Eur J Nutr 2019年9月
Changing industrial waste into healthy ingredients-Generating amino acids from soy pulp
journal of Environment and Safety 10(2) 17-20 2019年6月
2017年度
腸内細菌と治療 (1)腸内細菌に対する食物の影響
池松 真也
臨牀消化器内科 32(10) 1383-1388 2017年8月
Functional genomics of the Lactobacillus paracasei strain LC-Ikematsu isolated from the Okinawan natural environment
池松 真也
沖縄工業高等専門学校紀要 11 1-8 2017年3月
Genome Sequence of Lactobacillus paracasei Strain LC-Ikematsu, Isolated from a Pineapple in Okinawa, Japan
池松 真也
Genome Announcements 5(5) e01583-16 2017年2月
NMR spectroscopic structural characterization of a water-soluble β-(1→3, 1→6)-glucan from Aureobasidium pullulans
池松 真也
Carbohydrate Polymers 174 876-886 2017年
Two-dimensional NMR data of a water-soluble β-(1→3,1→6)-glucan from Aureobasidium pullulans and schizophyllan from Schizophyllum commune
Hiroyuki Kono, Nobuhiro Kondo, Katsuki Hirabayashi, Makoto Ogata, Kazuhide Totani, Shinya Ikematsu, Mitsumasa Osada
Data in Brief 15 382-388 2017年12月1日
Efficacy of urinary midkine as a biomarker in patients with acute kindney injury.
Hiroki Hayashi, Waichi Sato, Tomoki Kosugi, Kunihiro Nishimura, Daisuke Sugiyama, Naoko Asano, Shinya Ikematsu, Kimihiro Komori, Kimitoshi Nishiwaki, Kenji Kadomatsu, Seiichi Matsuo, Shoichi Mayuyama, Yukio Yazawa
CLINICAL AND EXPERIMENTAL NEPHROLOGY 21(4) 597-607 2017年8月
2016年度
The CCR4-NOT deadenylase activity contributes to generation of induced pluripotent stem cells
池松 真也
Biochemical and Biophysical Research Communications 474(2) 233-239 2016年
Analysis of lipids produced by microalgae isolated from the area around okinawa,japan
Shinya Ikematsu, Ipputa Tada, Yasuma Nagasaki
Applied Environmental Materials Science for Sustinabillity 222-233 2016年12月21日
2014年度
シークヮーサ種子を用いた抗酸化作用と美白効果素材の研究
池松 真也
化学と生物 52 2014年2月
2013年度
Expression of midkine in normal human skin, dermatitis, and neoplasms: Association with differentiation of keratinocytes
池松 真也
The Journal of Dermatology 40(12) 980-986 2013年
TEACHING STRATEGIES AND METHODS FOR GLOBAL EDUCATION THROUGH A SELF=EDUCATION BASED STUDENT EXCHANGE PROGRAM
池松真也
ISATE2013 2013年7月
Biotechnology Camp 2012 "carried out in collaboration with Nanyang Polytechnic and Okinawa National Collage of Technology
池松真也
ISATE2013 2013年7月
2009年度
中・尿中ミッドカイン測定系“ミッドカイン”―機能解析から臨床応用へ
池松 真也
医学のあゆみ 230(4) 285-289 2009年7月
The growth factor midkine regulates the renin-angiotensin system in mice
池松 真也
JClin Invest 119(6) 1616-1625 2009年6月
2008年度
Plasma midkine level is a prognostic factor for human neuroblastoma
池松 真也
Cancer Science 99(10) 2070-2074 2008年10月
Expression of the Heparin-Binding Growth Factor Midkine in the Cerebrospinal Fluid of Patients with Neurological Disorders
池松 真也
Internal Medicine 47(2) 83-89 2008年
Expression of the heparin-binding growth factor midkine in the cerebrospinal fluid of patients with neurological disorders
Yoshihiro Yoshida, Shinya Ikematsu, Hisako Muramatsu, Harutoshi Sakakima, Nobuhisa Mizuma, Fumiyo Matsuda, Ken Sonoda, Fujio Umehara, Ryuichi Ohkubo, Eiji Matsuura, Masamichi Goto, Mitsuhiro Osame, Takashi Muramatsu
INTERNAL MEDICINE 47(2) 83-89 2008年
2007年度
Midkine as a novel targetfor antibody therapy in osteosarcoma.
池松 真也
Biochem Biophys Res Commun 358(3) 757-762 2007年
新規な成長因子ミッドカインの体外診断への応用
池松 真也
沖縄工業高等専門学校紀要 1 17-23 2007年
Midkine and LDL-receptor-related protein 1 contribute to the auchorage-independent cell growth of cancer cells
Sen Chen, Guojun Bu, Yoshifumi Takei, Kazuma Sakamoto, Shinya Ikematsu, Takashi Muramatsu, Kenji Kadomatsu
JOURNAL OF CELL SCIENCE 120(22) 4009-4015 2007年11月
子宮内膜癌におけるミッドカインのマーカーとしての有用性
田辺廉二郎廉次郎,松本光代,赤平純一,鈴木貴,門松健治、,池松真也,笹野公伸,林慎一,八重樫伸生
日本癌学会総会記事 66回 503-503 2007年8月
2006年度
Protein tyrosine phosphatase receptor type Z is inactivated by ligand-induced oligomerzation
Masahide Fukada, Akihiro Fujikawa, Jeremy P.H. Chow, Shinya Ikematsu, Sasatoshi Sakuma, Masaharu Noda
FEBS Letters 580(17) 4051-4056 2006年7月24日
Doxorubicin-conjugated anti-midkine monoclonal antibody as a potential anti-tumor drug
K Inoh, H Muramatsu, S Torii, S Ikematsu, M Oda, H Kumai, S Sakuma, T Inui, T Kimura, T Muramatsu
JAPANESE JOURNAL OF CLINICAL ONCOLOGY 36(4) 207-211 2006年4月
2004年度
Midkine protects hepatocellular carcinoma cells against TRAIL-mediated apoptosis through down-regulation of caspase-3 activity.
池松 真也
Cancer 100(11) 2430-2436 2004年
2003年度
Correlation of elevated level of blood midkine with poor prognostic factors of human neuroblastomas.
池松 真也
Nagoya University 88(10) 1522-1526 2003年
Utilization of the promoter region of the midkine gene as a tool to drive therapeutic genes in a tumor specific manner.
池松 真也
Adv.Enzyme Regul. 57-66 2003年
Preoperative serum Midkine ncentration is a prognostic marker for esophageal squamous cell carcinoma.
池松 真也
Cancer Sci. 94(7) 628-632 2003年
High levels of urinary midkine in various cancer patients.
池松 真也
Biochem.Biophys.Res.Commun. 306(2) 329-332 2003年
Receptor-type protein Tyrosine phatase zeta as a component of the signaling receptor complex for idkine-dependent survival of mbryonic neurons.
池松 真也
Neurosci.Res. 45(2) 219-224 2003年
Increased serum midkine concentration as a possible tumor markerin patients with superficial esophageal cancer.
池松 真也
Oncol.Rep. 10(2) 411-414 2003年
Glycosaminoglycan structures required for strong binding to midkine, a heparin-binding growth factor.
池松 真也
Glycobiology 13(1) 35-42 2003年
Glypican-2 binds to midkine: The role of glypican-2 in neuronal cell adhesion and neurite outgrowth
N Kurosawa, GY Chen, K Kadomatsu, S Ikematsu, S Sakuma, T Muramatsu
GLYCOCONJUGATE JOURNAL 18(6) 499-507 2001年6月
2001年度
Glypican-2 binds to midkine: the role of glypican-2 in neuronal cell adhesion and neurite outgrowth.
池松 真也
Glycoconj.J. 18(6) 499-507 2001年
Haptotactic migration induced by midkine. Involvement of protein-tyrosine phosphatase zeta. Mitogen-activated protein kinase, and phosphatidylinositol 3-kinase.
池松 真也
J.Biol.Chem. 276(19) 15868-15875 2001年
Intraventricular administration of the neurotrophic factor midkine ameliorates hippocampal delayed neuronal death following transient forebrain ischemia in gerbils.
池松 真也
Brain Res. 894(1) 46-55 2001年
2000年度
Overexpression of midkine in pancreatic duct adenocarcinomas induced by N-Nitrosobis (2-oxopropyl)amine in hamsters and their cell lines.
池松 真也
Jpn.J.Cancer Res. 91(10) 979-986 2000年
神経栄養因子ミドカイン(MK)のスナネズミ遅発性神経細胞死に対する抑制作用
池松 真也
Brain Hypoxia 14 55-61 2000年
A heparin-binding growth factor, midkine, binds to a chondroitin sulfate proteoglycan, PG-M/versican.
池松 真也
Eur.J.Biochem. 267(13) 4046-4053 2000年
Serum midkine levels are increased in patients with various types of carcinomas.
池松 真也
Nagoya University 83(6) 701-706 2000年
An approach to the removal of Yeast specific O-linked oligo-mannoses from human midkine expressed in Pichia pastoris using site-specific mutagenesis.
池松 真也
J.Biochem. 128(5) 823-826 2000年
Neointima formation ina restenosis model is suppressed in midkine-deficient mice.
池松 真也
J.Clin.Invest. 105(4) 489-495 2000年
LDL receptor-related protein as a component of the midkine receptor.
池松 真也
Biochem.Biophys.Res.Commun. 270(3) 936-941 2000年
Midkine binds specifically to sulfatide the role of sulfatide in cell attachment to midkine-coated surfaces.
池松 真也
Eur.J.Biochem. 267(2) 344-351 2000年
Midkine rescues Wilms’tumor cells from cisplatin-induced apoptosis:regulation of Bcl-2 expression by Midkine.
池松 真也
J.Biochem. 127(2) 269-277 2000年
A heparin-binding growth factor midkine, binds to a chondrotin sulfate proteoglycan, PG-M/versican
K Zou, H Muramatsu, S Ikematsu, S Sakuma, RHM Satama, T Shinomura, K Kimata, T Muramatsu
EUROPEAN JOURNAL OF BIOCHEMISTORY 267(13) 4046-4053 2000年7月
1999年度
Frequent expression of midkine gene in esophageal cancer suggests a potential usage of its promoter for suicide gene therapy
池松 真也
Jpn.J.Cancer Res. 90(4) 469-475 1999年
Overexpression of midkine in lung tumors induced by N-nitrosobis(2-hydroxypropyl)amine in rats and its increase with progression
池松 真也
Carcinogenesis 20(3) 465-469 1999年
1998年度
神経栄養因子ミドカイン(MK)のスナネズミ遅発性神経細胞死に対する抑制作用
池松 真也
脳卒中 20(6) 720-724 1998年
1995年度
A Transgenic mouse line with alpha-1,3/4-fucosyltransferase cDNA production and characteristics.
池松 真也
Glycoconjugate J. 12(6) 795-801 1995年
1993年度
Transgenic mouse Lines with ectopic Expression of alpha-1,3-galactosyltransferase: production and characteristics.
池松 真也
Glycobiology 3(6) 575-580 1993年